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The map label for this gene is plsC [H]

Identifier: 116690724

GI number: 116690724

Start: 2995179

End: 2995943

Strand: Direct

Name: plsC [H]

Synonym: Bcen2424_2704

Alternate gene names: 116690724

Gene position: 2995179-2995943 (Clockwise)

Preceding gene: 116690723

Following gene: 116690725

Centisome position: 85.97

GC content: 65.62

Gene sequence:

>765_bases
ATGCGCTTCGTCCGCTCCCTGCTGCTGCTGATCTACTTCATCCTGTACACGGTGCCGTACGCCACCGCGTGTTTCATCGC
GTTCCCGTTCATGCGCCCCGACGCGCGCTACTGGATGGCGGCCGGCTGGTGCAAGTCGACGCTGTGGGTCGTGCGCTGGC
TGAACGGCATCCGCTACCGGATCGAAGGGTTCGAGAACCTGCCCGACGGCCCGGCCGTGCTGCTGTCGAAGCACCAGTCC
GCGTGGGAGACGCTCGCGTTTCCGGCGCTGATGCCCAAGCCGCTGTGCTATGTGTTCAAGCGCGAGCTGCTGTACGTGCC
GTTCTTCGGCTGGGCGCTCGGGCTGCTGCACATGGTCAACATCAATCGCAAGGAAGGCAAGAACGCGTTCGCGTCGGTGA
TCCGCCAGGGCAAGAAGCGCCTGTCGGAAGGCGCATGGATGATCATGTTCCCCGAAGGCACGCGCACGCCGGTCGGCAAG
CAGGGCAAATACAAGACGGGCGGCGCGCGCTTCGCGATCGAAACCGGCACGCCGGTCGTGCCGATCGCGCACAATGCAGG
TCGTGTGTGGCCGCGCAACTCGTTCACGAAATTCCCGGGCGTCGTCACGGTGTCGATCGGCAAGCCGATCGCGAGCGAAG
GGCTGACGCCCGACGCATTGAACTCGCAGGTCGAAGCGTGGATCGAAGCGGAAATGCGCCGCATCGATCCCGAGGCGTAT
CGTCAGGCGGGCAACGCCGGCACCCGCGATGCCGCGCGCGCCTGA

Upstream 100 bases:

>100_bases
GTCCACGACGATCTGCGCGCGTTTGCGCTCGATTTTCTTTCACACGAACACGAGTGATGCGGCTGCCGCGCGCATCCTCC
CCAACGCCAGACTCACGCCG

Downstream 100 bases:

>100_bases
CGCCCCGGATTGCAGCCGTTGCGTACGACAAAAAGAAGCGAACTGATGAAACAGCGTCCGCGGCCACGGCCTGCCGTCGT
GGCCCTCGATCATCGCCAGA

Product: phospholipid/glycerol acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MRFVRSLLLLIYFILYTVPYATACFIAFPFMRPDARYWMAAGWCKSTLWVVRWLNGIRYRIEGFENLPDGPAVLLSKHQS
AWETLAFPALMPKPLCYVFKRELLYVPFFGWALGLLHMVNINRKEGKNAFASVIRQGKKRLSEGAWMIMFPEGTRTPVGK
QGKYKTGGARFAIETGTPVVPIAHNAGRVWPRNSFTKFPGVVTVSIGKPIASEGLTPDALNSQVEAWIEAEMRRIDPEAY
RQAGNAGTRDAARA

Sequences:

>Translated_254_residues
MRFVRSLLLLIYFILYTVPYATACFIAFPFMRPDARYWMAAGWCKSTLWVVRWLNGIRYRIEGFENLPDGPAVLLSKHQS
AWETLAFPALMPKPLCYVFKRELLYVPFFGWALGLLHMVNINRKEGKNAFASVIRQGKKRLSEGAWMIMFPEGTRTPVGK
QGKYKTGGARFAIETGTPVVPIAHNAGRVWPRNSFTKFPGVVTVSIGKPIASEGLTPDALNSQVEAWIEAEMRRIDPEAY
RQAGNAGTRDAARA
>Mature_254_residues
MRFVRSLLLLIYFILYTVPYATACFIAFPFMRPDARYWMAAGWCKSTLWVVRWLNGIRYRIEGFENLPDGPAVLLSKHQS
AWETLAFPALMPKPLCYVFKRELLYVPFFGWALGLLHMVNINRKEGKNAFASVIRQGKKRLSEGAWMIMFPEGTRTPVGK
QGKYKTGGARFAIETGTPVVPIAHNAGRVWPRNSFTKFPGVVTVSIGKPIASEGLTPDALNSQVEAWIEAEMRRIDPEAY
RQAGNAGTRDAARA

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=194, Percent_Identity=28.8659793814433, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI15100175, Length=194, Percent_Identity=28.8659793814433, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI6041665, Length=174, Percent_Identity=28.1609195402299, Blast_Score=75, Evalue=4e-14,
Organism=Escherichia coli, GI1789395, Length=184, Percent_Identity=28.804347826087, Blast_Score=65, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17564032, Length=271, Percent_Identity=26.1992619926199, Blast_Score=81, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6320151, Length=206, Percent_Identity=26.2135922330097, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281364648, Length=223, Percent_Identity=26.457399103139, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24582856, Length=223, Percent_Identity=26.457399103139, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24582854, Length=223, Percent_Identity=26.457399103139, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641614, Length=221, Percent_Identity=26.2443438914027, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641612, Length=221, Percent_Identity=26.2443438914027, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 28620; Mature: 28620

Theoretical pI: Translated: 10.51; Mature: 10.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFVRSLLLLIYFILYTVPYATACFIAFPFMRPDARYWMAAGWCKSTLWVVRWLNGIRYR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEE
IEGFENLPDGPAVLLSKHQSAWETLAFPALMPKPLCYVFKRELLYVPFFGWALGLLHMVN
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHC
INRKEGKNAFASVIRQGKKRLSEGAWMIMFPEGTRTPVGKQGKYKTGGARFAIETGTPVV
CCHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCEE
PIAHNAGRVWPRNSFTKFPGVVTVSIGKPIASEGLTPDALNSQVEAWIEAEMRRIDPEAY
EEECCCCCCCCCCCCCCCCCEEEEECCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHH
RQAGNAGTRDAARA
HHCCCCCCCHHCCC
>Mature Secondary Structure
MRFVRSLLLLIYFILYTVPYATACFIAFPFMRPDARYWMAAGWCKSTLWVVRWLNGIRYR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEE
IEGFENLPDGPAVLLSKHQSAWETLAFPALMPKPLCYVFKRELLYVPFFGWALGLLHMVN
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHC
INRKEGKNAFASVIRQGKKRLSEGAWMIMFPEGTRTPVGKQGKYKTGGARFAIETGTPVV
CCHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCEE
PIAHNAGRVWPRNSFTKFPGVVTVSIGKPIASEGLTPDALNSQVEAWIEAEMRRIDPEAY
EEECCCCCCCCCCCCCCCCCEEEEECCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHH
RQAGNAGTRDAARA
HHCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9403685; 7812434 [H]