Click here to switch to the map view.

The map label for this gene is erg3 [H]

Identifier: 116690640

GI number: 116690640

Start: 2902955

End: 2903869

Strand: Direct

Name: erg3 [H]

Synonym: Bcen2424_2620

Alternate gene names: 116690640

Gene position: 2902955-2903869 (Clockwise)

Preceding gene: 116690639

Following gene: 116690641

Centisome position: 83.32

GC content: 65.36

Gene sequence:

>915_bases
ATGCGATTCGACGTCGAATTGCTTCTGCTCGCGCTGGCGCCCGTCTTCCTGCTCTGCATCGCGTGGGAGGCCTGGCACCT
CGCCCGCACCCGTGCGCAGGACCGCATCTATGCGTGGCGCGACACGCTGTGCAACGCGGCGCTCGCGCTGATGCACCAGG
GCGCCGACAAGCTCGCGTGGCTGTTCGTGATTCCCGTCTATGCGTACTGCTACCGGCACTATCGCGTCTACACGTGGCAC
GACGGCTGGCTGTCGTTCGCGGTGCTGTTCGTCGCGCAGGACTTCCTCTACTACGTATTCCATCGCGCGAGCCATCGCGT
GCGCTGGCTGTGGGCCGCGCACGTCGTGCACCACTCGTCCGAGCGGATGAATTTCTCGACCGCCTTCCGCCAGAGCCTGA
TGTACCCGGTCGCGGGCATGTGGCTGTTCTGGCTGCCGCTCGCGTTCGCCGGCTTTCCGCCGCAACAGGTCGTCGGCATC
GTGCTGATCAACCTCGCGTTCCAGTTCTTCGTGCACACGCAGGCGATCGGCAAGCTCGGCTGGCTCGAATACGTGCTCAA
CACGCCGTCGATCCACCGTGCGCACCATGCGCGCAACGCGCGCTACATCGATCGTAATTACGCAGGCGTCCTGGTGATCT
GGGATCGCCTGTTCGGCAGCTATGTCGAGGAAACGCCCGACGATCCGCCGCAGTACGGCATCGTCGAGCGGCTCGGCTCG
AACAACCCGTTCGTCGCGACGTTTCACGAGTGGGTGTCGATGGCGTCCGACGCGTTGCGCGTCGACGGATGGCGCAACAA
GCTGCGCGCGATTTTCGGCCCGCCCGAATGGGCGAGCGCTTATCATGCGCAGATTGCCGAGGCCGCGAACCAGGGTCCGC
GCACCGAGCCGCTGGCGGCTGCGCGCGATCGATAA

Upstream 100 bases:

>100_bases
TAGCGCGTAGCGATTGCGTAGGCTGTTGGCCTGACGATATCTACAACGGGCCACACGCCCGGCCTGATGGCTTGCAGGGG
AACGAAGGAGACACACGCCC

Downstream 100 bases:

>100_bases
ACCGTTTCAGCCAACGGCCGCCGCGCAGCCCGGAACCGAGCAGGCACGCGGCAGATGAGAAACACATCAGGCCATATCTA
CGAGGAGATCGAACGATGCA

Product: sterol desaturase-like protein

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MRFDVELLLLALAPVFLLCIAWEAWHLARTRAQDRIYAWRDTLCNAALALMHQGADKLAWLFVIPVYAYCYRHYRVYTWH
DGWLSFAVLFVAQDFLYYVFHRASHRVRWLWAAHVVHHSSERMNFSTAFRQSLMYPVAGMWLFWLPLAFAGFPPQQVVGI
VLINLAFQFFVHTQAIGKLGWLEYVLNTPSIHRAHHARNARYIDRNYAGVLVIWDRLFGSYVEETPDDPPQYGIVERLGS
NNPFVATFHEWVSMASDALRVDGWRNKLRAIFGPPEWASAYHAQIAEAANQGPRTEPLAAARDR

Sequences:

>Translated_304_residues
MRFDVELLLLALAPVFLLCIAWEAWHLARTRAQDRIYAWRDTLCNAALALMHQGADKLAWLFVIPVYAYCYRHYRVYTWH
DGWLSFAVLFVAQDFLYYVFHRASHRVRWLWAAHVVHHSSERMNFSTAFRQSLMYPVAGMWLFWLPLAFAGFPPQQVVGI
VLINLAFQFFVHTQAIGKLGWLEYVLNTPSIHRAHHARNARYIDRNYAGVLVIWDRLFGSYVEETPDDPPQYGIVERLGS
NNPFVATFHEWVSMASDALRVDGWRNKLRAIFGPPEWASAYHAQIAEAANQGPRTEPLAAARDR
>Mature_304_residues
MRFDVELLLLALAPVFLLCIAWEAWHLARTRAQDRIYAWRDTLCNAALALMHQGADKLAWLFVIPVYAYCYRHYRVYTWH
DGWLSFAVLFVAQDFLYYVFHRASHRVRWLWAAHVVHHSSERMNFSTAFRQSLMYPVAGMWLFWLPLAFAGFPPQQVVGI
VLINLAFQFFVHTQAIGKLGWLEYVLNTPSIHRAHHARNARYIDRNYAGVLVIWDRLFGSYVEETPDDPPQYGIVERLGS
NNPFVATFHEWVSMASDALRVDGWRNKLRAIFGPPEWASAYHAQIAEAANQGPRTEPLAAARDR

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=215, Percent_Identity=41.3953488372093, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI25144659, Length=256, Percent_Identity=35.15625, Blast_Score=141, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 35292; Mature: 35292

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFDVELLLLALAPVFLLCIAWEAWHLARTRAQDRIYAWRDTLCNAALALMHQGADKLAW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LFVIPVYAYCYRHYRVYTWHDGWLSFAVLFVAQDFLYYVFHRASHRVRWLWAAHVVHHSS
HHHHHHHHHHHHHCEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCH
ERMNFSTAFRQSLMYPVAGMWLFWLPLAFAGFPPQQVVGIVLINLAFQFFVHTQAIGKLG
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLEYVLNTPSIHRAHHARNARYIDRNYAGVLVIWDRLFGSYVEETPDDPPQYGIVERLGS
HHHHHHCCCCHHHHHHHCCCCEECCCCCCCEEEHHHHHHHHHHCCCCCCCCHHHHHHHCC
NNPFVATFHEWVSMASDALRVDGWRNKLRAIFGPPEWASAYHAQIAEAANQGPRTEPLAA
CCCEEEHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
ARDR
CCCC
>Mature Secondary Structure
MRFDVELLLLALAPVFLLCIAWEAWHLARTRAQDRIYAWRDTLCNAALALMHQGADKLAW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
LFVIPVYAYCYRHYRVYTWHDGWLSFAVLFVAQDFLYYVFHRASHRVRWLWAAHVVHHSS
HHHHHHHHHHHHHCEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCH
ERMNFSTAFRQSLMYPVAGMWLFWLPLAFAGFPPQQVVGIVLINLAFQFFVHTQAIGKLG
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLEYVLNTPSIHRAHHARNARYIDRNYAGVLVIWDRLFGSYVEETPDDPPQYGIVERLGS
HHHHHHCCCCHHHHHHHCCCCEECCCCCCCEEEHHHHHHHHHHCCCCCCCCHHHHHHHCC
NNPFVATFHEWVSMASDALRVDGWRNKLRAIFGPPEWASAYHAQIAEAANQGPRTEPLAA
CCCEEEHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
ARDR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]