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The map label for this gene is kbaZ [H]

Identifier: 116690616

GI number: 116690616

Start: 2874164

End: 2875516

Strand: Reverse

Name: kbaZ [H]

Synonym: Bcen2424_2596

Alternate gene names: 116690616

Gene position: 2875516-2874164 (Counterclockwise)

Preceding gene: 116690617

Following gene: 116690615

Centisome position: 82.54

GC content: 71.69

Gene sequence:

>1353_bases
ATGTCCGGCCTGACGACCGTTGCCGAACGCCCGCGCACCGCGCACGCGGACACCGTGCTGCGGATGATCTTCGACGCGAA
CCGCGCGGACGCGCAGCGCGGCATCTATTCGGTCTGCAGCGCGCACCGGCTGGTGCTGGAGGCCGCGTGCGAAGCCGCGC
GCGCGGACGGCTCGCCGCTCTTGATCGAGGCGACCTGCAATCAGGTCAACCATCTCGGCGGCTATACGGGCATGACGCCG
GCCGATTTTCGTCGCGACGTCGATGCGATTGCCGCGCGCTGCGGGCTCGCGTCGTCGGCGCTCGTGCTCGGCGGCGACCA
TCTCGGCCCGAACCCGTGGCGGCACCGTCGCGCGGCCGACGCGATGCGGGAAGCCGCTGCGATGGTCGCCGCGTATGTCG
AAGCCGGTTTCGAAAAGATCCACCTCGATGCGAGCATGGCGTGCGCGGACGATCCGGCACGGCTCGACGATCGCACGATC
GCCGCGCGCGCGGCGGAGCTGTGCCGTGTCGCGGAAGACGCGGCGGCGCGCGTCGGGATCGCGCCCGTCTACGTGATCGG
CACCGAGGTGCCGACGCCGGGCGGCGAGGTGAGCGGCGACGCAAGTAACGATGCGATCGCGCAGATCGCGGTCACGCGCA
GCGACAGCATCGCGGCGACGCTCGACGCGCACCGCCGCGCGTTCTCGGCGGCCGGGCTCGACGACGCGTGGACGCGCGTC
GTCGCGATCGTCGCGCAGCCGGGCGTCGACTTCGACGATCGCCACGTGCTCGATTACGACAGTGCCAAGGCCGCGTCACT
GGGCGCGAGTATCCTGCAGACACCGCGCCTCGTGTTCGAAGCGCATTCGACCGATTACCAGACGGAAGCCGCGCTCGCCG
CGCTGGTGCGCGACCACTTCGCGGTGCTGAAGGTCGGCCCCGCGCTGACGTTCGCGCTGCGCGAGGCGCTGTTCGCGCTG
ACGTTCATCGAGGACGCGCTGATCGACGACGTCGCGCAGCGCTCGCGGTTGCGCGACGTCGTCGATGCGGCGATGCGCGC
GCAGCCCGAACACTGGGCGCCGTACTACCGCGGCGACGAGACCGCGCAGCGGCTCGCGCGCCAGTTCAGCTACAGCGACC
GCATCCGCTATTACTGGCTGCAGCCGGCCGTCGCGGCCGCGGTCGAGCAGCTGTTCGGCAACCTCGCGCGGCAGCCGGTG
CCGGAGACGCTCGTCGCGCAGTGGCTGCCGGATGTCTACGCGGCGTGCCGCGCGGGCGGCCTCGCGAAAGAGCCGCGCGC
ATGGGTGCGCCACCGGATACGCGACGTGATCGCGCACTATGCGCGCGCGTGCGGGATGCAGCGGCCGGCATGA

Upstream 100 bases:

>100_bases
CGAACGCGGCCGGCGCGATCGCGGTCACGCGGCGCGGCCCGATGGAAGGCAACAGCAGCGCGGCCGAGATCGACCGCTTC
CTGACCGAACGGGGGATCGC

Downstream 100 bases:

>100_bases
CGGGCCGCGAAGGAAACGACGCAACACCGACACAAGACCGACGACATTTCGAACAATCACAGGAGACATGCCATGCAACG
AAAGATGCTCGACGCCGCCG

Product: tagatose-6-phosphate kinase

Products: ADP; D-tagatose 1,6-bisphosphate

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MSGLTTVAERPRTAHADTVLRMIFDANRADAQRGIYSVCSAHRLVLEAACEAARADGSPLLIEATCNQVNHLGGYTGMTP
ADFRRDVDAIAARCGLASSALVLGGDHLGPNPWRHRRAADAMREAAAMVAAYVEAGFEKIHLDASMACADDPARLDDRTI
AARAAELCRVAEDAAARVGIAPVYVIGTEVPTPGGEVSGDASNDAIAQIAVTRSDSIAATLDAHRRAFSAAGLDDAWTRV
VAIVAQPGVDFDDRHVLDYDSAKAASLGASILQTPRLVFEAHSTDYQTEAALAALVRDHFAVLKVGPALTFALREALFAL
TFIEDALIDDVAQRSRLRDVVDAAMRAQPEHWAPYYRGDETAQRLARQFSYSDRIRYYWLQPAVAAAVEQLFGNLARQPV
PETLVAQWLPDVYAACRAGGLAKEPRAWVRHRIRDVIAHYARACGMQRPA

Sequences:

>Translated_450_residues
MSGLTTVAERPRTAHADTVLRMIFDANRADAQRGIYSVCSAHRLVLEAACEAARADGSPLLIEATCNQVNHLGGYTGMTP
ADFRRDVDAIAARCGLASSALVLGGDHLGPNPWRHRRAADAMREAAAMVAAYVEAGFEKIHLDASMACADDPARLDDRTI
AARAAELCRVAEDAAARVGIAPVYVIGTEVPTPGGEVSGDASNDAIAQIAVTRSDSIAATLDAHRRAFSAAGLDDAWTRV
VAIVAQPGVDFDDRHVLDYDSAKAASLGASILQTPRLVFEAHSTDYQTEAALAALVRDHFAVLKVGPALTFALREALFAL
TFIEDALIDDVAQRSRLRDVVDAAMRAQPEHWAPYYRGDETAQRLARQFSYSDRIRYYWLQPAVAAAVEQLFGNLARQPV
PETLVAQWLPDVYAACRAGGLAKEPRAWVRHRIRDVIAHYARACGMQRPA
>Mature_449_residues
SGLTTVAERPRTAHADTVLRMIFDANRADAQRGIYSVCSAHRLVLEAACEAARADGSPLLIEATCNQVNHLGGYTGMTPA
DFRRDVDAIAARCGLASSALVLGGDHLGPNPWRHRRAADAMREAAAMVAAYVEAGFEKIHLDASMACADDPARLDDRTIA
ARAAELCRVAEDAAARVGIAPVYVIGTEVPTPGGEVSGDASNDAIAQIAVTRSDSIAATLDAHRRAFSAAGLDDAWTRVV
AIVAQPGVDFDDRHVLDYDSAKAASLGASILQTPRLVFEAHSTDYQTEAALAALVRDHFAVLKVGPALTFALREALFALT
FIEDALIDDVAQRSRLRDVVDAAMRAQPEHWAPYYRGDETAQRLARQFSYSDRIRYYWLQPAVAAAVEQLFGNLARQPVP
ETLVAQWLPDVYAACRAGGLAKEPRAWVRHRIRDVIAHYARACGMQRPA

Specific function: Component of the tagatose-1,6-bisphosphate aldolase kbaYZ that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of kbaY. When expressed alone, kbaZ does not show any aldol

COG id: COG4573

COG function: function code G; Predicted tagatose 6-phosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gatZ/kbaZ family. KbaZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789520, Length=423, Percent_Identity=51.063829787234, Blast_Score=411, Evalue=1e-116,
Organism=Escherichia coli, GI1788411, Length=426, Percent_Identity=46.9483568075117, Blast_Score=367, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012062 [H]

Pfam domain/function: PF08013 Tagatose_6_P_K [H]

EC number: 2.7.1.144

Molecular weight: Translated: 48606; Mature: 48475

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGLTTVAERPRTAHADTVLRMIFDANRADAQRGIYSVCSAHRLVLEAACEAARADGSPL
CCCCCHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
LIEATCNQVNHLGGYTGMTPADFRRDVDAIAARCGLASSALVLGGDHLGPNPWRHRRAAD
EEEEHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHH
AMREAAAMVAAYVEAGFEKIHLDASMACADDPARLDDRTIAARAAELCRVAEDAAARVGI
HHHHHHHHHHHHHHHCHHHEECCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
APVYVIGTEVPTPGGEVSGDASNDAIAQIAVTRSDSIAATLDAHRRAFSAAGLDDAWTRV
CEEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHH
VAIVAQPGVDFDDRHVLDYDSAKAASLGASILQTPRLVFEAHSTDYQTEAALAALVRDHF
HHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHCCHHHEEECCCCCHHHHHHHHHHHHHH
AVLKVGPALTFALREALFALTFIEDALIDDVAQRSRLRDVVDAAMRAQPEHWAPYYRGDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
TAQRLARQFSYSDRIRYYWLQPAVAAAVEQLFGNLARQPVPETLVAQWLPDVYAACRAGG
HHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
LAKEPRAWVRHRIRDVIAHYARACGMQRPA
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SGLTTVAERPRTAHADTVLRMIFDANRADAQRGIYSVCSAHRLVLEAACEAARADGSPL
CCCCHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
LIEATCNQVNHLGGYTGMTPADFRRDVDAIAARCGLASSALVLGGDHLGPNPWRHRRAAD
EEEEHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHH
AMREAAAMVAAYVEAGFEKIHLDASMACADDPARLDDRTIAARAAELCRVAEDAAARVGI
HHHHHHHHHHHHHHHCHHHEECCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
APVYVIGTEVPTPGGEVSGDASNDAIAQIAVTRSDSIAATLDAHRRAFSAAGLDDAWTRV
CEEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHH
VAIVAQPGVDFDDRHVLDYDSAKAASLGASILQTPRLVFEAHSTDYQTEAALAALVRDHF
HHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHCCHHHEEECCCCCHHHHHHHHHHHHHH
AVLKVGPALTFALREALFALTFIEDALIDDVAQRSRLRDVVDAAMRAQPEHWAPYYRGDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
TAQRLARQFSYSDRIRYYWLQPAVAAAVEQLFGNLARQPVPETLVAQWLPDVYAACRAGG
HHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
LAKEPRAWVRHRIRDVIAHYARACGMQRPA
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; D-tagatose 6-phosphate

Specific reaction: ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate

General reaction: Phospho group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA