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The map label for this gene is murB [H]

Identifier: 116690574

GI number: 116690574

Start: 2829899

End: 2830948

Strand: Reverse

Name: murB [H]

Synonym: Bcen2424_2554

Alternate gene names: 116690574

Gene position: 2830948-2829899 (Counterclockwise)

Preceding gene: 116690576

Following gene: 116690572

Centisome position: 81.26

GC content: 72.0

Gene sequence:

>1050_bases
ATGCCGATGCCCCCTGACGATTCCGCCCTGTCGCTGCTTCCCGACCATCCGCTCGCCGCGCACAACACGTTCGGCATCGC
CGCGCGTGCGCGCTTCGCCGCGCGCATCACGCAGGCGGCGCAGTTCGAGGCGCTGCATCGCGACCCGCGGGTCGCGAACC
TGCCGCAGCTCGTGCTCGGCGGCGGCAGCAACATCGTGTTCACGCGCGATTTCGACGGCGTCGTGCTGCTCGACGAGATC
GCGGGCCGCCGCGTCGTGCGCGAGGACGACGACGCGTGGTACGTCGAGGCCGGCGGCGGCGAGAACTGGCACGCGTTCGT
CGCGTGGACGCTCGAGCACGGGATGCCGGGCCTCGAGAATCTCGCGCTGATCCCGGGCACCGTCGGCGCCGCGCCGATCC
AGAACATCGGCGCGTACGGCCTCGAGATGAAGGCGTATTTCGATTCGCTGGTCGCGGTGGAGCTGGCGACGGGGCGCCGC
GAGCGCTTCGACGCCGCGCGCTGCGCGTTCGGTTACCGCGACAGTTTCTTCAAGCGGGAAGGGCGCGGCCGGTTCGCGAT
CGTCGCGGTGACGTTCCGGCTGCCGAAGCAATGGACGCCGCGGCTCGGCTATGCGGACGTCACGCGCGAGCTCGACGCGC
GCGGCATCACGCCCGAGGCGGCAACGCCGCGCGACGTGTTCGATGCGGTCGTCGCGATCCGCCGCGCGAAGCTGCCCGAT
CCGCTGGTGCTCGGCAACGCGGGCAGTTTCTTCAAGAATCCGGTGATCGACGCCGCGCAATTCGATGCGCTGCGCGCTCG
CGCGCCGGATGTCGTGTCGTATCCGCAGCCGGACGGGCAGGTGAAGCTCGCGGCCGGCTGGCTGATCGACCGCTGCGGCT
GGAAGGGGCGCGCGCTCGGCGCGGCGGCCGTGCACGACCGCCAGGCGCTCGTGCTCGTCAATCGCGGCGGCGCGACCGGC
GCCGACGTGCTGGCGCTGGCGCGGGCCATCCAGGCCGACGTGCGCGCGCAGTTCGGCGTCGAGCTGGAGGCGGAACCGGT
CTGCCTGTAA

Upstream 100 bases:

>100_bases
CACGGGCACTCGCTATAATTGCGGACTGTTTGCCATTTTACCGATGCCCCTCCGTTTGCCCAAGGCCGGCCATGCGCCGC
CCGGGCCGACGTGACCGCGA

Downstream 100 bases:

>100_bases
CGTAGCGCGCGCCGGTTTTGGCGCGCCCAAACGAAAGCGCCGATCGTCGACCGGCGCTTTTTTTACGCGTGTGCGTTGAG
CGGCGCGTCAGTGCTTGAGG

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MPMPPDDSALSLLPDHPLAAHNTFGIAARARFAARITQAAQFEALHRDPRVANLPQLVLGGGSNIVFTRDFDGVVLLDEI
AGRRVVREDDDAWYVEAGGGENWHAFVAWTLEHGMPGLENLALIPGTVGAAPIQNIGAYGLEMKAYFDSLVAVELATGRR
ERFDAARCAFGYRDSFFKREGRGRFAIVAVTFRLPKQWTPRLGYADVTRELDARGITPEAATPRDVFDAVVAIRRAKLPD
PLVLGNAGSFFKNPVIDAAQFDALRARAPDVVSYPQPDGQVKLAAGWLIDRCGWKGRALGAAAVHDRQALVLVNRGGATG
ADVLALARAIQADVRAQFGVELEAEPVCL

Sequences:

>Translated_349_residues
MPMPPDDSALSLLPDHPLAAHNTFGIAARARFAARITQAAQFEALHRDPRVANLPQLVLGGGSNIVFTRDFDGVVLLDEI
AGRRVVREDDDAWYVEAGGGENWHAFVAWTLEHGMPGLENLALIPGTVGAAPIQNIGAYGLEMKAYFDSLVAVELATGRR
ERFDAARCAFGYRDSFFKREGRGRFAIVAVTFRLPKQWTPRLGYADVTRELDARGITPEAATPRDVFDAVVAIRRAKLPD
PLVLGNAGSFFKNPVIDAAQFDALRARAPDVVSYPQPDGQVKLAAGWLIDRCGWKGRALGAAAVHDRQALVLVNRGGATG
ADVLALARAIQADVRAQFGVELEAEPVCL
>Mature_348_residues
PMPPDDSALSLLPDHPLAAHNTFGIAARARFAARITQAAQFEALHRDPRVANLPQLVLGGGSNIVFTRDFDGVVLLDEIA
GRRVVREDDDAWYVEAGGGENWHAFVAWTLEHGMPGLENLALIPGTVGAAPIQNIGAYGLEMKAYFDSLVAVELATGRRE
RFDAARCAFGYRDSFFKREGRGRFAIVAVTFRLPKQWTPRLGYADVTRELDARGITPEAATPRDVFDAVVAIRRAKLPDP
LVLGNAGSFFKNPVIDAAQFDALRARAPDVVSYPQPDGQVKLAAGWLIDRCGWKGRALGAAAVHDRQALVLVNRGGATGA
DVLALARAIQADVRAQFGVELEAEPVCL

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=334, Percent_Identity=50.5988023952096, Blast_Score=324, Evalue=7e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 37729; Mature: 37598

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMPPDDSALSLLPDHPLAAHNTFGIAARARFAARITQAAQFEALHRDPRVANLPQLVLG
CCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEC
GGSNIVFTRDFDGVVLLDEIAGRRVVREDDDAWYVEAGGGENWHAFVAWTLEHGMPGLEN
CCCEEEEEECCCCEEEEEHHCCCEEEECCCCEEEEECCCCCCEEEEEEEEECCCCCCCCC
LALIPGTVGAAPIQNIGAYGLEMKAYFDSLVAVELATGRRERFDAARCAFGYRDSFFKRE
EEECCCCCCCCCHHHCCCCCEEHHHHHHHHEEEEECCCCHHHHHHHHHHCCCHHHHHHHC
GRGRFAIVAVTFRLPKQWTPRLGYADVTRELDARGITPEAATPRDVFDAVVAIRRAKLPD
CCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCC
PLVLGNAGSFFKNPVIDAAQFDALRARAPDVVSYPQPDGQVKLAAGWLIDRCGWKGRALG
CEEECCCCCHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEECEEECCCCCCCCCCC
AAAVHDRQALVLVNRGGATGADVLALARAIQADVRAQFGVELEAEPVCL
HHEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEECCCCCCC
>Mature Secondary Structure 
PMPPDDSALSLLPDHPLAAHNTFGIAARARFAARITQAAQFEALHRDPRVANLPQLVLG
CCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEC
GGSNIVFTRDFDGVVLLDEIAGRRVVREDDDAWYVEAGGGENWHAFVAWTLEHGMPGLEN
CCCEEEEEECCCCEEEEEHHCCCEEEECCCCEEEEECCCCCCEEEEEEEEECCCCCCCCC
LALIPGTVGAAPIQNIGAYGLEMKAYFDSLVAVELATGRRERFDAARCAFGYRDSFFKRE
EEECCCCCCCCCHHHCCCCCEEHHHHHHHHEEEEECCCCHHHHHHHHHHCCCHHHHHHHC
GRGRFAIVAVTFRLPKQWTPRLGYADVTRELDARGITPEAATPRDVFDAVVAIRRAKLPD
CCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCC
PLVLGNAGSFFKNPVIDAAQFDALRARAPDVVSYPQPDGQVKLAAGWLIDRCGWKGRALG
CEEECCCCCHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEECEEECCCCCCCCCCC
AAAVHDRQALVLVNRGGATGADVLALARAIQADVRAQFGVELEAEPVCL
HHEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA