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The map label for this gene is nadB1 [H]

Identifier: 116690524

GI number: 116690524

Start: 2771999

End: 2773585

Strand: Direct

Name: nadB1 [H]

Synonym: Bcen2424_2504

Alternate gene names: 116690524

Gene position: 2771999-2773585 (Clockwise)

Preceding gene: 116690523

Following gene: 116690531

Centisome position: 79.57

GC content: 67.04

Gene sequence:

>1587_bases
ATGAAATTCGACGTGGCGATCGTCGGCAGCGGCCTGGCAGGGCTGTCGGTCGCACTCAACCTGGCCAGCACGCGACGTGT
CGCACTGATCGCGAAACGTTCGATGATGGAGGGGGCGAGCGATAACGCGCAAGGCGGCATCGCGGCGGTCCTCGACTCGG
CGGACAGTATCGAGAACCACGTCGACGACACGCTGGTCGCCGGCGGCGGCCTGTGCGACGAAGGCGCGACGCGCTACATC
GTCGAGCACGGGCGCGAAGCCATCGAATGGCTGATCTCGCAAGGCGTCCCGTTCACGAAGGACGACGCGGCCGAACTCGG
CTTTCACCTGACGCGCGAAGGCGGCCACAGCCACCGGCGAATCATCCATGCGGCCGATGCGACCGGCCATGCGGTGCTCG
CGACGCTGTCGGAACGGGCGCGCCAGCATCCGAACATCACGTTCTTCGAAAACCACCACGCAATCGACCTGATCACGTCC
GACCGGCTCGGCCTGCCCGGCCGCCGCTGTCACGGCCTGTATGCGCTCGACGTCGACAACGACCGCACGATCACGATCGA
GGCGCCGCACACCGTGCTCGCCACCGGCGGCGCCGGCAAGGTCTACCTGTACACGACGAACCCCGACACCGCGACCGGCG
ACGGCATCGCGATGGCATGGCGGGCGGGCTGCCGCGTGTCGAACATGGAATTCATCCAGTTCCACCCGACCTGCCTGTTC
CATCCGTATGCGAAGTCGTTCCTGATTTCGGAGGCCGTGCGCGGCGAAGGCGGCCTGCTGAAGCTGCCCGACGGCACCCG
CTTCATGCCCTCGCACGATCCGCGCGCGGAGCTCGCGCCGCGCGACATCGTCGCGCGCGCGATCGACTTCGAGATCAAGA
AGCGCGGGATCGACTGCGTGTATCTCGACATCAGCCATCAGCCGGAAGCGTTCCTGCGCGAACACTTCCCGATGATTCAT
GCGCGCTGCCTCGAATTCGGCATCGACATCGCGAAACAGCCGATTCCCGTCGTGCCGGCCGCGCACTATACGTGCGGCGG
CGTCGTCACCGATCTCGCGGGGCGCACCGATCTCGCCGGCCTGTATGCGGTCGGCGAAACGTCGTACACGGGGCTGCACG
GCGCGAACCGGCTCGCGAGCAACTCGCTGCTCGAATGTCTCGTGATCGGCCGCGCGGCAGCCGAGGCGATCGAGGCGGCG
GGCTTCGACGCCGACACGCCGGCCACGCTGCCCGCGTGGGACGAAAGCCGTGTGTCGGATGCGGACGAGGAAGTCGTCGT
CGCACACAACTGGGACGAACTGCGCCGCCTGATGTGGAACTATGTCGGCATCGTGCGCACCGACAAGCGCCTCGAACGCG
CGAAACATCGCCTGTCGCTGCTGCGCGACGAGATCCACGAGTACTACGCGAACTTCCGCGTGACACGCGATCTGCTCGAA
CTGCGCAACCTGGTCGACGTGGCCACGCTGATCGTCAAGAGTGCGCACTCCCGCCGCGAAAGCCGCGGGTTGCACTACAG
CCGCGACTGGCCGCATACGCTGCCGAAGGCGTTGCCGAGCGTGCTCACGCCGCGCGTGCGCCGCTGA

Upstream 100 bases:

>100_bases
TTTGCGCGCACGCTCGAGCCCGACGCGGTATGCTCTCCCCTTTCCGCGGCCGCGGCCGCCGGAACGCACAAGATCAAAAG
CGTAACGATGGAGATGCAGC

Downstream 100 bases:

>100_bases
GCGGCGCGCCGCCCTGCCCGGCGGCGGCCGCAGCACAAGAAAAAAGCCGTTGGCGTTTGCGCGCCAACGGCTTTTTGTCT
GATCGGACGACGTTCGGTCA

Product: L-aspartate oxidase

Products: NA

Alternate protein names: LASPO 1; Quinolinate synthase B 1 [H]

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MKFDVAIVGSGLAGLSVALNLASTRRVALIAKRSMMEGASDNAQGGIAAVLDSADSIENHVDDTLVAGGGLCDEGATRYI
VEHGREAIEWLISQGVPFTKDDAAELGFHLTREGGHSHRRIIHAADATGHAVLATLSERARQHPNITFFENHHAIDLITS
DRLGLPGRRCHGLYALDVDNDRTITIEAPHTVLATGGAGKVYLYTTNPDTATGDGIAMAWRAGCRVSNMEFIQFHPTCLF
HPYAKSFLISEAVRGEGGLLKLPDGTRFMPSHDPRAELAPRDIVARAIDFEIKKRGIDCVYLDISHQPEAFLREHFPMIH
ARCLEFGIDIAKQPIPVVPAAHYTCGGVVTDLAGRTDLAGLYAVGETSYTGLHGANRLASNSLLECLVIGRAAAEAIEAA
GFDADTPATLPAWDESRVSDADEEVVVAHNWDELRRLMWNYVGIVRTDKRLERAKHRLSLLRDEIHEYYANFRVTRDLLE
LRNLVDVATLIVKSAHSRRESRGLHYSRDWPHTLPKALPSVLTPRVRR

Sequences:

>Translated_528_residues
MKFDVAIVGSGLAGLSVALNLASTRRVALIAKRSMMEGASDNAQGGIAAVLDSADSIENHVDDTLVAGGGLCDEGATRYI
VEHGREAIEWLISQGVPFTKDDAAELGFHLTREGGHSHRRIIHAADATGHAVLATLSERARQHPNITFFENHHAIDLITS
DRLGLPGRRCHGLYALDVDNDRTITIEAPHTVLATGGAGKVYLYTTNPDTATGDGIAMAWRAGCRVSNMEFIQFHPTCLF
HPYAKSFLISEAVRGEGGLLKLPDGTRFMPSHDPRAELAPRDIVARAIDFEIKKRGIDCVYLDISHQPEAFLREHFPMIH
ARCLEFGIDIAKQPIPVVPAAHYTCGGVVTDLAGRTDLAGLYAVGETSYTGLHGANRLASNSLLECLVIGRAAAEAIEAA
GFDADTPATLPAWDESRVSDADEEVVVAHNWDELRRLMWNYVGIVRTDKRLERAKHRLSLLRDEIHEYYANFRVTRDLLE
LRNLVDVATLIVKSAHSRRESRGLHYSRDWPHTLPKALPSVLTPRVRR
>Mature_528_residues
MKFDVAIVGSGLAGLSVALNLASTRRVALIAKRSMMEGASDNAQGGIAAVLDSADSIENHVDDTLVAGGGLCDEGATRYI
VEHGREAIEWLISQGVPFTKDDAAELGFHLTREGGHSHRRIIHAADATGHAVLATLSERARQHPNITFFENHHAIDLITS
DRLGLPGRRCHGLYALDVDNDRTITIEAPHTVLATGGAGKVYLYTTNPDTATGDGIAMAWRAGCRVSNMEFIQFHPTCLF
HPYAKSFLISEAVRGEGGLLKLPDGTRFMPSHDPRAELAPRDIVARAIDFEIKKRGIDCVYLDISHQPEAFLREHFPMIH
ARCLEFGIDIAKQPIPVVPAAHYTCGGVVTDLAGRTDLAGLYAVGETSYTGLHGANRLASNSLLECLVIGRAAAEAIEAA
GFDADTPATLPAWDESRVSDADEEVVVAHNWDELRRLMWNYVGIVRTDKRLERAKHRLSLLRDEIHEYYANFRVTRDLLE
LRNLVDVATLIVKSAHSRRESRGLHYSRDWPHTLPKALPSVLTPRVRR

Specific function: Catalyzes the oxidation of L-aspartate to iminoaspartate [H]

COG id: COG0029

COG function: function code H; Aspartate oxidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily [H]

Homologues:

Organism=Homo sapiens, GI156416003, Length=506, Percent_Identity=34.5849802371541, Blast_Score=241, Evalue=1e-63,
Organism=Escherichia coli, GI1788928, Length=524, Percent_Identity=59.9236641221374, Blast_Score=644, Evalue=0.0,
Organism=Escherichia coli, GI1790597, Length=524, Percent_Identity=36.4503816793893, Blast_Score=259, Evalue=4e-70,
Organism=Escherichia coli, GI1786942, Length=551, Percent_Identity=33.7568058076225, Blast_Score=224, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17550100, Length=528, Percent_Identity=33.7121212121212, Blast_Score=238, Evalue=7e-63,
Organism=Caenorhabditis elegans, GI17505833, Length=529, Percent_Identity=32.8922495274102, Blast_Score=236, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI71986328, Length=468, Percent_Identity=28.2051282051282, Blast_Score=98, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6322701, Length=527, Percent_Identity=33.2068311195446, Blast_Score=228, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6322416, Length=514, Percent_Identity=33.0739299610895, Blast_Score=223, Evalue=6e-59,
Organism=Saccharomyces cerevisiae, GI6322511, Length=483, Percent_Identity=27.7432712215321, Blast_Score=113, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6320788, Length=476, Percent_Identity=27.9411764705882, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI17137288, Length=533, Percent_Identity=33.2082551594747, Blast_Score=237, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24655642, Length=533, Percent_Identity=33.2082551594747, Blast_Score=237, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24655647, Length=533, Percent_Identity=33.2082551594747, Blast_Score=237, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24663005, Length=551, Percent_Identity=32.8493647912886, Blast_Score=228, Evalue=5e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953
- InterPro:   IPR013027
- InterPro:   IPR015939
- InterPro:   IPR004112
- InterPro:   IPR005288 [H]

Pfam domain/function: PF00890 FAD_binding_2; PF02910 Succ_DH_flav_C [H]

EC number: =1.4.3.16 [H]

Molecular weight: Translated: 57974; Mature: 57974

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFDVAIVGSGLAGLSVALNLASTRRVALIAKRSMMEGASDNAQGGIAAVLDSADSIENH
CEEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHH
VDDTLVAGGGLCDEGATRYIVEHGREAIEWLISQGVPFTKDDAAELGFHLTREGGHSHRR
HCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCEEEECCCCCCCEE
IIHAADATGHAVLATLSERARQHPNITFFENHHAIDLITSDRLGLPGRRCHGLYALDVDN
EEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCCCCHHCEEEEEECCC
DRTITIEAPHTVLATGGAGKVYLYTTNPDTATGDGIAMAWRAGCRVSNMEFIQFHPTCLF
CCEEEEECCCEEEEECCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCEEEEEECCCEEE
HPYAKSFLISEAVRGEGGLLKLPDGTRFMPSHDPRAELAPRDIVARAIDFEIKKRGIDCV
CHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEE
YLDISHQPEAFLREHFPMIHARCLEFGIDIAKQPIPVVPAAHYTCGGVVTDLAGRTDLAG
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCCE
LYAVGETSYTGLHGANRLASNSLLECLVIGRAAAEAIEAAGFDADTPATLPAWDESRVSD
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
ADEEVVVAHNWDELRRLMWNYVGIVRTDKRLERAKHRLSLLRDEIHEYYANFRVTRDLLE
CCCCEEEEECHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRNLVDVATLIVKSAHSRRESRGLHYSRDWPHTLPKALPSVLTPRVRR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKFDVAIVGSGLAGLSVALNLASTRRVALIAKRSMMEGASDNAQGGIAAVLDSADSIENH
CEEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHH
VDDTLVAGGGLCDEGATRYIVEHGREAIEWLISQGVPFTKDDAAELGFHLTREGGHSHRR
HCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCEEEECCCCCCCEE
IIHAADATGHAVLATLSERARQHPNITFFENHHAIDLITSDRLGLPGRRCHGLYALDVDN
EEEECCCCCHHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCCCCHHCEEEEEECCC
DRTITIEAPHTVLATGGAGKVYLYTTNPDTATGDGIAMAWRAGCRVSNMEFIQFHPTCLF
CCEEEEECCCEEEEECCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCEEEEEECCCEEE
HPYAKSFLISEAVRGEGGLLKLPDGTRFMPSHDPRAELAPRDIVARAIDFEIKKRGIDCV
CHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEE
YLDISHQPEAFLREHFPMIHARCLEFGIDIAKQPIPVVPAAHYTCGGVVTDLAGRTDLAG
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCCE
LYAVGETSYTGLHGANRLASNSLLECLVIGRAAAEAIEAAGFDADTPATLPAWDESRVSD
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
ADEEVVVAHNWDELRRLMWNYVGIVRTDKRLERAKHRLSLLRDEIHEYYANFRVTRDLLE
CCCCEEEEECHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRNLVDVATLIVKSAHSRRESRGLHYSRDWPHTLPKALPSVLTPRVRR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]