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The map label for this gene is nahR [H]

Identifier: 116690429

GI number: 116690429

Start: 2669886

End: 2670812

Strand: Direct

Name: nahR [H]

Synonym: Bcen2424_2409

Alternate gene names: 116690429

Gene position: 2669886-2670812 (Clockwise)

Preceding gene: 116690427

Following gene: 116690430

Centisome position: 76.63

GC content: 70.12

Gene sequence:

>927_bases
ATGATGCATCCCGATCTGCGCCGCCTCGACCTGAATCTGCTGCTCGTATTCGACGCGCTGTACCGCCATCGGTCTGTCGC
GGCGGCCGCGCATGAGCTCGCGTTGAGCCCGTCGGCGTTGAGCCACGCGCTCGCCCGGCTGCGCGACGCGATCGGCGATG
CGCTGTTCGTGCGCCTCGGCAACGAGATGCAGCCGACCGTGCGCGCCGACGACATCGCCACCTGGGCCGGCGACGCGCTC
GACGCGATGTCGAAAGGGCTCGCCCGCGCGCGCCGCTTCGATCCCGCGCAAAGCGACCGCACGTTCGTGTTCGCCGCGAC
CGACTACACGGCGTTCGCGGTGCTGCCGGCGTTCCTCGCCCGCATCCAGCACGTGGCGCCGCACCTGCGGGTCCGCGTCG
TCCATTCGGACCGCAAGATTTCCGTCGACGAACTCGCGGCCGGCCGCATCGACTTCGCGCTCGGCTACCACGAGGAATCG
GCGGCCGACGCGCCGGGCATCGAGGATTTCGACTGGTTCTCCGACGACTACGTCGTGATCGCGAGCGCCGCGCATCCGGA
CATCCGGCGGCGGCTGACGCTCGACCAGTACCTGGCGGCCCGCCACGTGGTCGTCACGCCATGGAACGAGTCGCGCGGTG
TCGTCGACTACGTGCTCGACCGGCTCGGTCTCGCGCGGCATGTGGCCGTGCAGTTGCCGACCGTGCTGGCCGCGCCGTTC
GTGATCGCGGAGTCGGCACTCCTGATGACGGTGCCGAACCGCGCCGCGCAGGCGCTGCGGCATGCGGCGCCGATCCGCAT
CTTCCCCGCGCCGTTCGAGATCCCGCGCTACACGGTGAAGGTCTACTCGCACGCGAAGCATGCGCGCACCGATGCGCACC
GCTGGATTCGCGCCCAGTTACTCGACGCACGGCCGCCCCCAGACTAA

Upstream 100 bases:

>100_bases
GGAAAACGGTGCCGCGCACCCGCGCTGGCGCCGTTCGAACCGTCATGCTACGTTCACGCCACGCCTGCAGGAAGTGCAGT
TTCTTCATCCAGACCTGAAC

Downstream 100 bases:

>100_bases
GCGCGGCGCGTTGCGGGGCGGGGGGTTTCAGGCGTCGATCGGCGCTGTCGGCAATCGCCCGAATCATTACGAAATACTTA
CCAATTTCGCGACTTTCACG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MMHPDLRRLDLNLLLVFDALYRHRSVAAAAHELALSPSALSHALARLRDAIGDALFVRLGNEMQPTVRADDIATWAGDAL
DAMSKGLARARRFDPAQSDRTFVFAATDYTAFAVLPAFLARIQHVAPHLRVRVVHSDRKISVDELAAGRIDFALGYHEES
AADAPGIEDFDWFSDDYVVIASAAHPDIRRRLTLDQYLAARHVVVTPWNESRGVVDYVLDRLGLARHVAVQLPTVLAAPF
VIAESALLMTVPNRAAQALRHAAPIRIFPAPFEIPRYTVKVYSHAKHARTDAHRWIRAQLLDARPPPD

Sequences:

>Translated_308_residues
MMHPDLRRLDLNLLLVFDALYRHRSVAAAAHELALSPSALSHALARLRDAIGDALFVRLGNEMQPTVRADDIATWAGDAL
DAMSKGLARARRFDPAQSDRTFVFAATDYTAFAVLPAFLARIQHVAPHLRVRVVHSDRKISVDELAAGRIDFALGYHEES
AADAPGIEDFDWFSDDYVVIASAAHPDIRRRLTLDQYLAARHVVVTPWNESRGVVDYVLDRLGLARHVAVQLPTVLAAPF
VIAESALLMTVPNRAAQALRHAAPIRIFPAPFEIPRYTVKVYSHAKHARTDAHRWIRAQLLDARPPPD
>Mature_308_residues
MMHPDLRRLDLNLLLVFDALYRHRSVAAAAHELALSPSALSHALARLRDAIGDALFVRLGNEMQPTVRADDIATWAGDAL
DAMSKGLARARRFDPAQSDRTFVFAATDYTAFAVLPAFLARIQHVAPHLRVRVVHSDRKISVDELAAGRIDFALGYHEES
AADAPGIEDFDWFSDDYVVIASAAHPDIRRRLTLDQYLAARHVVVTPWNESRGVVDYVLDRLGLARHVAVQLPTVLAAPF
VIAESALLMTVPNRAAQALRHAAPIRIFPAPFEIPRYTVKVYSHAKHARTDAHRWIRAQLLDARPPPD

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=308, Percent_Identity=26.2987012987013, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI87081766, Length=271, Percent_Identity=25.4612546125461, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790147, Length=271, Percent_Identity=27.3062730627306, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786820, Length=62, Percent_Identity=46.7741935483871, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34253; Mature: 34253

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMHPDLRRLDLNLLLVFDALYRHRSVAAAAHELALSPSALSHALARLRDAIGDALFVRLG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEEEHCC
NEMQPTVRADDIATWAGDALDAMSKGLARARRFDPAQSDRTFVFAATDYTAFAVLPAFLA
CCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHH
RIQHVAPHLRVRVVHSDRKISVDELAAGRIDFALGYHEESAADAPGIEDFDWFSDDYVVI
HHHHHCCCEEEEEEECCCCCCHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEE
ASAAHPDIRRRLTLDQYLAARHVVVTPWNESRGVVDYVLDRLGLARHVAVQLPTVLAAPF
EECCCCHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIAESALLMTVPNRAAQALRHAAPIRIFPAPFEIPRYTVKVYSHAKHARTDAHRWIRAQL
HHHCCEEEEECCHHHHHHHHHCCCCEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHH
LDARPPPD
HCCCCCCC
>Mature Secondary Structure
MMHPDLRRLDLNLLLVFDALYRHRSVAAAAHELALSPSALSHALARLRDAIGDALFVRLG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEEEHCC
NEMQPTVRADDIATWAGDALDAMSKGLARARRFDPAQSDRTFVFAATDYTAFAVLPAFLA
CCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHH
RIQHVAPHLRVRVVHSDRKISVDELAAGRIDFALGYHEESAADAPGIEDFDWFSDDYVVI
HHHHHCCCEEEEEEECCCCCCHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEE
ASAAHPDIRRRLTLDQYLAARHVVVTPWNESRGVVDYVLDRLGLARHVAVQLPTVLAAPF
EECCCCHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIAESALLMTVPNRAAQALRHAAPIRIFPAPFEIPRYTVKVYSHAKHARTDAHRWIRAQL
HHHCCEEEEECCHHHHHHHHHCCCCEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHH
LDARPPPD
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]