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The map label for this gene is mdmC [H]

Identifier: 116690400

GI number: 116690400

Start: 2646299

End: 2647075

Strand: Reverse

Name: mdmC [H]

Synonym: Bcen2424_2380

Alternate gene names: 116690400

Gene position: 2647075-2646299 (Counterclockwise)

Preceding gene: 116690401

Following gene: 116690398

Centisome position: 75.98

GC content: 59.33

Gene sequence:

>777_bases
ATGGCGGATAGCGGTCGCTGGAAACGCCGTCTACGTGATCAATCTCGTCAAGGAATGCACTTGGTTTCTACCACCCACGC
TCTTTTGCAACGGCTTCATGAAGAGAGCCAGCGCGAAATCATCGCCCGCGCACGCGCGCAGTTTCAGGGGCCGAACGAGG
CGTTTCCGACGCTCGTCGACGAATACGAAGCACTCGCTCCGAGGTTGCGAGGGCGGTTTCTCGAAACGTTCGGCTTGTTC
ACCGAAGATTTCGAGTCATCGGCAGGCAGTGCTTTATCGTTGGCCGTATCGGCGGAAACGGGAAGGTTCTTGCGCAACAT
GGTGCTCGCGCAACGGCCGACCAGAATCCTCGAACTCGGCAGTTCGTGCGGCGTGTCGACTTTGTATTTCGCCGACGCGT
TGCGCACGCTGGGCCGTGGCGTGGTCATCGCGACCGAATGCGATGCGCTCAAGTGCGCGCGTTTGCGGGCTCATGTCGAA
GCTGCGGGTCTGGATGCCTATGTCGACTTGAGGGAAGGCGATGTGTTCGAGACGGTTGCCGCGCTGGATGGGACCGTCGA
CATGGTGTTTATCGATGTCTGGGCCGACGCCTATCTGAAGCTGTTCAAGCAGATCGAGCGCTTGCTGCGGCCGGGATCGG
TCGTGCTGGCTGACAACATGTACACGGCCGAGGACGCCGTTCGACCTTACAAGCGCTACCTCAACGAGGATCCGCGGTTT
TCGACCACGACGCTGGATTTTGAGTCGGGGGTTGAGTTTACGGTTGTCGTGGCTTGA

Upstream 100 bases:

>100_bases
CTTTGCGTGACGGCGTGCCCTGAACGCGCGATTACGCTTGCTCGACTGGCATAGCGTCACCCGTGTTTGCTGATGATGGA
GTGATAGCGCCGCAGGCCTG

Downstream 100 bases:

>100_bases
GGGGAGTTTCTTGTGAATCCGGAGGCATGGAGACTTGGCTGGTCCCGACAGAATTCATGCGTCAATGGCAGCGGGGAATT
GCGGACGGGTTTTGGAAATT

Product: O-methyltransferase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MADSGRWKRRLRDQSRQGMHLVSTTHALLQRLHEESQREIIARARAQFQGPNEAFPTLVDEYEALAPRLRGRFLETFGLF
TEDFESSAGSALSLAVSAETGRFLRNMVLAQRPTRILELGSSCGVSTLYFADALRTLGRGVVIATECDALKCARLRAHVE
AAGLDAYVDLREGDVFETVAALDGTVDMVFIDVWADAYLKLFKQIERLLRPGSVVLADNMYTAEDAVRPYKRYLNEDPRF
STTTLDFESGVEFTVVVA

Sequences:

>Translated_258_residues
MADSGRWKRRLRDQSRQGMHLVSTTHALLQRLHEESQREIIARARAQFQGPNEAFPTLVDEYEALAPRLRGRFLETFGLF
TEDFESSAGSALSLAVSAETGRFLRNMVLAQRPTRILELGSSCGVSTLYFADALRTLGRGVVIATECDALKCARLRAHVE
AAGLDAYVDLREGDVFETVAALDGTVDMVFIDVWADAYLKLFKQIERLLRPGSVVLADNMYTAEDAVRPYKRYLNEDPRF
STTTLDFESGVEFTVVVA
>Mature_257_residues
ADSGRWKRRLRDQSRQGMHLVSTTHALLQRLHEESQREIIARARAQFQGPNEAFPTLVDEYEALAPRLRGRFLETFGLFT
EDFESSAGSALSLAVSAETGRFLRNMVLAQRPTRILELGSSCGVSTLYFADALRTLGRGVVIATECDALKCARLRAHVEA
AGLDAYVDLREGDVFETVAALDGTVDMVFIDVWADAYLKLFKQIERLLRPGSVVLADNMYTAEDAVRPYKRYLNEDPRFS
TTTLDFESGVEFTVVVA

Specific function: 4-O-methyltransferase for the lactone ring of midecamycin and other macrolide antibiotics [H]

COG id: COG4122

COG function: function code R; Predicted O-methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. Type 3 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002935 [H]

Pfam domain/function: PF01596 Methyltransf_3 [H]

EC number: NA

Molecular weight: Translated: 28848; Mature: 28717

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADSGRWKRRLRDQSRQGMHLVSTTHALLQRLHEESQREIIARARAQFQGPNEAFPTLVD
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
EYEALAPRLRGRFLETFGLFTEDFESSAGSALSLAVSAETGRFLRNMVLAQRPTRILELG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHCCHHHHHCC
SSCGVSTLYFADALRTLGRGVVIATECDALKCARLRAHVEAAGLDAYVDLREGDVFETVA
CCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHH
ALDGTVDMVFIDVWADAYLKLFKQIERLLRPGSVVLADNMYTAEDAVRPYKRYLNEDPRF
HHCCCHHEEHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCCCCC
STTTLDFESGVEFTVVVA
CEEEEECCCCCCEEEEEC
>Mature Secondary Structure 
ADSGRWKRRLRDQSRQGMHLVSTTHALLQRLHEESQREIIARARAQFQGPNEAFPTLVD
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
EYEALAPRLRGRFLETFGLFTEDFESSAGSALSLAVSAETGRFLRNMVLAQRPTRILELG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHCCHHHHHCC
SSCGVSTLYFADALRTLGRGVVIATECDALKCARLRAHVEAAGLDAYVDLREGDVFETVA
CCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHH
ALDGTVDMVFIDVWADAYLKLFKQIERLLRPGSVVLADNMYTAEDAVRPYKRYLNEDPRF
HHCCCHHEEHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCCCCC
STTTLDFESGVEFTVVVA
CEEEEECCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1629172 [H]