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The map label for this gene is upp [H]

Identifier: 116690314

GI number: 116690314

Start: 2548938

End: 2549654

Strand: Direct

Name: upp [H]

Synonym: Bcen2424_2293

Alternate gene names: 116690314

Gene position: 2548938-2549654 (Clockwise)

Preceding gene: 116690297

Following gene: 116690315

Centisome position: 73.16

GC content: 67.5

Gene sequence:

>717_bases
ATGAGCGACGACCGGCCCATGCCCGCCGCCGCCCCCGATCCCCTTTTGCCGCCAAGGCACCCCGTCATGAAACAGGACAG
CCGTTTCCCGAACCTCTTCATCACCGATCACCCGCTGATCCAGCACAAGCTCACGCACATGCGCGACAAGGACACGTCCA
CGCGCACGTTCCGCGAACTGCTGCGCGAGATCACGCTGCTGATGGGCTATGAGATCACCCGCAACCTGCCGATCACGACC
AAGCGGGTCGAAACCCCGCTGGTGGCGGTCGACGCGCCGGTGATCGCCGGCAAGAAGCTCGCGATCGTGCCTGTGCTGCG
CGCGGGCATCGGGATGTCGGACGGCCTGCTCGATCTGGTGCCGTCCGCGCGCGTCGGCCACATCGGCGTGTACCGCGCCG
AGGACCACCGTCCGGTCGAATACCTGGTGCGCCTGCCGGACCTGGAAGACCGCATCTTCATCCTGTGCGACCCGATGGTC
GCGACCGGCTATTCGGCCGTGCATGCGGTCGACGTGCTCAAGCGCCGCAACGTGCCGGCCGCGAACATCATGTTCGTCGC
GCTGGTCGCCGCGCCCGAGGGCGTGCAGGTGTTCCAGGACGCGCACCCCGACGTGAAGCTGTTCGTCGCGTCGCTCGACT
CGCACCTGAACGAGCACGCGTACATCGTGCCGGGCCTGGGCGACGCCGGCGACCGCCTGTTCGGCACCAAGAACTGA

Upstream 100 bases:

>100_bases
GGCCGCCGGCGGCGGGCAAACGGGCGTGCGCGGCACGCGGATTGTCGTGAGACGTCGATAATATCCGGATCGCGCGGCGC
GCCTTGGTAAAATTGCGGGC

Downstream 100 bases:

>100_bases
GCGCACCGGGCGTCGGGCGCCGCCATGCCGCGCGCCCCGGCGCGCCGCGACGGCCGGCCCGGCCGTTCGGCCATGCGCGG
CGGCCCCGAAGCGGCGGTCG

Product: uracil phosphoribosyltransferase

Products: NA

Alternate protein names: UMP pyrophosphorylase; UPRTase [H]

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MSDDRPMPAAAPDPLLPPRHPVMKQDSRFPNLFITDHPLIQHKLTHMRDKDTSTRTFRELLREITLLMGYEITRNLPITT
KRVETPLVAVDAPVIAGKKLAIVPVLRAGIGMSDGLLDLVPSARVGHIGVYRAEDHRPVEYLVRLPDLEDRIFILCDPMV
ATGYSAVHAVDVLKRRNVPAANIMFVALVAAPEGVQVFQDAHPDVKLFVASLDSHLNEHAYIVPGLGDAGDRLFGTKN

Sequences:

>Translated_238_residues
MSDDRPMPAAAPDPLLPPRHPVMKQDSRFPNLFITDHPLIQHKLTHMRDKDTSTRTFRELLREITLLMGYEITRNLPITT
KRVETPLVAVDAPVIAGKKLAIVPVLRAGIGMSDGLLDLVPSARVGHIGVYRAEDHRPVEYLVRLPDLEDRIFILCDPMV
ATGYSAVHAVDVLKRRNVPAANIMFVALVAAPEGVQVFQDAHPDVKLFVASLDSHLNEHAYIVPGLGDAGDRLFGTKN
>Mature_237_residues
SDDRPMPAAAPDPLLPPRHPVMKQDSRFPNLFITDHPLIQHKLTHMRDKDTSTRTFRELLREITLLMGYEITRNLPITTK
RVETPLVAVDAPVIAGKKLAIVPVLRAGIGMSDGLLDLVPSARVGHIGVYRAEDHRPVEYLVRLPDLEDRIFILCDPMVA
TGYSAVHAVDVLKRRNVPAANIMFVALVAAPEGVQVFQDAHPDVKLFVASLDSHLNEHAYIVPGLGDAGDRLFGTKN

Specific function: Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate [H]

COG id: COG0035

COG function: function code F; Uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPRTase family [H]

Homologues:

Organism=Homo sapiens, GI57863312, Length=202, Percent_Identity=32.6732673267327, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI301129207, Length=202, Percent_Identity=32.6732673267327, Blast_Score=88, Evalue=7e-18,
Organism=Escherichia coli, GI87082118, Length=203, Percent_Identity=47.7832512315271, Blast_Score=196, Evalue=8e-52,
Organism=Caenorhabditis elegans, GI17539894, Length=212, Percent_Identity=28.7735849056604, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17539892, Length=212, Percent_Identity=28.7735849056604, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6321920, Length=192, Percent_Identity=36.4583333333333, Blast_Score=114, Evalue=1e-26,
Organism=Drosophila melanogaster, GI45550449, Length=207, Percent_Identity=34.2995169082126, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28573516, Length=207, Percent_Identity=34.2995169082126, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28573514, Length=207, Percent_Identity=34.2995169082126, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28573512, Length=207, Percent_Identity=34.2995169082126, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21358379, Length=171, Percent_Identity=30.4093567251462, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: 2580 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005765 [H]

Pfam domain/function: NA

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 26322; Mature: 26191

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDDRPMPAAAPDPLLPPRHPVMKQDSRFPNLFITDHPLIQHKLTHMRDKDTSTRTFREL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCHHHHHHHH
LREITLLMGYEITRNLPITTKRVETPLVAVDAPVIAGKKLAIVPVLRAGIGMSDGLLDLV
HHHHHHHHCHHHHCCCCCCHHHCCCCEEEECCCEECCCCEEEHHHHHHCCCCCCCHHHHC
PSARVGHIGVYRAEDHRPVEYLVRLPDLEDRIFILCDPMVATGYSAVHAVDVLKRRNVPA
CCCCCCEEEEEECCCCCCHHHEEECCCCCCCEEEEECCHHHCCHHHHHHHHHHHHCCCCH
ANIMFVALVAAPEGVQVFQDAHPDVKLFVASLDSHLNEHAYIVPGLGDAGDRLFGTKN
HHEEEEEEEECCCCHHHHHCCCCCCEEHHHHHHHHCCCCEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
SDDRPMPAAAPDPLLPPRHPVMKQDSRFPNLFITDHPLIQHKLTHMRDKDTSTRTFREL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCHHHHHHHH
LREITLLMGYEITRNLPITTKRVETPLVAVDAPVIAGKKLAIVPVLRAGIGMSDGLLDLV
HHHHHHHHCHHHHCCCCCCHHHCCCCEEEECCCEECCCCEEEHHHHHHCCCCCCCHHHHC
PSARVGHIGVYRAEDHRPVEYLVRLPDLEDRIFILCDPMVATGYSAVHAVDVLKRRNVPA
CCCCCCEEEEEECCCCCCHHHEEECCCCCCCEEEEECCHHHCCHHHHHHHHHHHHCCCCH
ANIMFVALVAAPEGVQVFQDAHPDVKLFVASLDSHLNEHAYIVPGLGDAGDRLFGTKN
HHEEEEEEEECCCCHHHHHCCCCCCEEHHHHHHHHCCCCEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA