Click here to switch to the map view.

The map label for this gene is kdpE [H]

Identifier: 116690305

GI number: 116690305

Start: 2537773

End: 2538471

Strand: Reverse

Name: kdpE [H]

Synonym: Bcen2424_2284

Alternate gene names: 116690305

Gene position: 2538471-2537773 (Counterclockwise)

Preceding gene: 116690306

Following gene: 116690304

Centisome position: 72.86

GC content: 69.67

Gene sequence:

>699_bases
ATGAGTGAACCCAGCCTGACCGTCGTCCTGATCGAGGACGAAAAGCAGATCCGCCGCTTCGTGCGCGCCGCGCTCGAAGA
GGAGGACATCGCGGTGTTCGAGGCCGAGACGGGCAAGCAGGGGCTGATCGACGCGGCGACGCGCAAGCCCGATCTCGTGA
TCGTCGATCTCGGCCTGCCCGATACCGACGGCCTCGACGTGATCCGCGAGCTGCGCGGCTGGTCCGAGGTGCCGGTGATC
GTGCTGTCCGCCCGCACGCAGGAAGAGGAGAAGGTCGCGGCGCTCGACGCGGGCGCCGACGACTACCTGACCAAGCCGTT
CGGCGTGTCCGAACTGCGTGCGCGGATGCGCGCGCAACTGCGCCGGCGCAACCAGGGCGGCGCGAACGAGTCGCCGAAGG
TGAGCTTCGGCACCGTGACCGTCGATCTCGCGCTGCGCCAGGTGTGGCGCGACGACGCGATCGTCCACCTGACGCCGCTC
GAATACCGGCTGCTCGCGACGCTCGTGCGTCACGCGGGGCGCGTGCTCACGCACCGCCAGCTGCTGCGCGACGTGTGGGG
GCCGTCGCACGTCGAGAGCCATCACTATCTGCGCATCTACATGGCGCACCTGCGCCAGAAGCTCGAGGCCGATCCCGCGC
AGCCCGAGCACATCGTCACCGAGACGGGCGTCGGCTACCGGCTCGTCGGCGCCGTGTGA

Upstream 100 bases:

>100_bases
TTCACGCTGCCGGTCGACACGCCGCCGGCCGCCCCCGCCGTGCCCGACGACGAATCCGACCTGCCGGGCGCATCGCCCCC
ATCCGAGTCATTGCCAGACC

Downstream 100 bases:

>100_bases
CGGGCGGTGGGTAGCGGCGCATGCGGCCGTGACGCCGCGCATCGGCGGGGTTGCGCCGGCGCGACAGCCTCGCGATGAGC
GCCGGCCCTGCACACCGGCT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MSEPSLTVVLIEDEKQIRRFVRAALEEEDIAVFEAETGKQGLIDAATRKPDLVIVDLGLPDTDGLDVIRELRGWSEVPVI
VLSARTQEEEKVAALDAGADDYLTKPFGVSELRARMRAQLRRRNQGGANESPKVSFGTVTVDLALRQVWRDDAIVHLTPL
EYRLLATLVRHAGRVLTHRQLLRDVWGPSHVESHHYLRIYMAHLRQKLEADPAQPEHIVTETGVGYRLVGAV

Sequences:

>Translated_232_residues
MSEPSLTVVLIEDEKQIRRFVRAALEEEDIAVFEAETGKQGLIDAATRKPDLVIVDLGLPDTDGLDVIRELRGWSEVPVI
VLSARTQEEEKVAALDAGADDYLTKPFGVSELRARMRAQLRRRNQGGANESPKVSFGTVTVDLALRQVWRDDAIVHLTPL
EYRLLATLVRHAGRVLTHRQLLRDVWGPSHVESHHYLRIYMAHLRQKLEADPAQPEHIVTETGVGYRLVGAV
>Mature_231_residues
SEPSLTVVLIEDEKQIRRFVRAALEEEDIAVFEAETGKQGLIDAATRKPDLVIVDLGLPDTDGLDVIRELRGWSEVPVIV
LSARTQEEEKVAALDAGADDYLTKPFGVSELRARMRAQLRRRNQGGANESPKVSFGTVTVDLALRQVWRDDAIVHLTPLE
YRLLATLVRHAGRVLTHRQLLRDVWGPSHVESHHYLRIYMAHLRQKLEADPAQPEHIVTETGVGYRLVGAV

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=63.2286995515695, Blast_Score=290, Evalue=4e-80,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=37.3873873873874, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=35.3982300884956, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=34.6666666666667, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=32.8888888888889, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=35.1111111111111, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1789809, Length=235, Percent_Identity=31.9148936170213, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=30.8370044052863, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=32.4444444444444, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=35.1111111111111, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=30.5676855895196, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=30.5676855895196, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=29.6943231441048, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=29.3103448275862, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=33.0188679245283, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=31.404958677686, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1790437, Length=159, Percent_Identity=27.0440251572327, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26034; Mature: 25903

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPSLTVVLIEDEKQIRRFVRAALEEEDIAVFEAETGKQGLIDAATRKPDLVIVDLGLP
CCCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHCCCCCEEEEECCCC
DTDGLDVIRELRGWSEVPVIVLSARTQEEEKVAALDAGADDYLTKPFGVSELRARMRAQL
CCCHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHCCCCCHHCCCCCCHHHHHHHHHHHH
RRRNQGGANESPKVSFGTVTVDLALRQVWRDDAIVHLTPLEYRLLATLVRHAGRVLTHRQ
HHHCCCCCCCCCCEEEEEEHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHH
LLRDVWGPSHVESHHYLRIYMAHLRQKLEADPAQPEHIVTETGVGYRLVGAV
HHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCEEEECCC
>Mature Secondary Structure 
SEPSLTVVLIEDEKQIRRFVRAALEEEDIAVFEAETGKQGLIDAATRKPDLVIVDLGLP
CCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHCCCCCEEEEECCCC
DTDGLDVIRELRGWSEVPVIVLSARTQEEEKVAALDAGADDYLTKPFGVSELRARMRAQL
CCCHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHCCCCCHHCCCCCCHHHHHHHHHHHH
RRRNQGGANESPKVSFGTVTVDLALRQVWRDDAIVHLTPLEYRLLATLVRHAGRVLTHRQ
HHHCCCCCCCCCCEEEEEEHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHH
LLRDVWGPSHVESHHYLRIYMAHLRQKLEADPAQPEHIVTETGVGYRLVGAV
HHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]