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The map label for this gene is can [H]

Identifier: 116690278

GI number: 116690278

Start: 2512156

End: 2512800

Strand: Direct

Name: can [H]

Synonym: Bcen2424_2257

Alternate gene names: 116690278

Gene position: 2512156-2512800 (Clockwise)

Preceding gene: 116690277

Following gene: 116690279

Centisome position: 72.11

GC content: 70.7

Gene sequence:

>645_bases
ATGAATCGCCCCAAGAGCATGCTGGTTGCCAACATTGCCTGGGCCCGCGAGACGCGCGAACACACGCCCGGCTTTTTCGA
CGCGCTCGCGCGCGGCCAGAATCCGCGCGTACTGTGGATCGGTTGCGCGGACAGCCGCGTGCCAGCCGAAACCATCACGC
ACTGCGCGCCCGGCGAGCTGTTCGTCCATCGCAACATCGCGAACCTGTTCCACCCCGACGACGACAATTCCGCCAGCGTG
CTCGAGTACGCGGTGCGGGTGCTGAAGGTCGACCACGTGATCGTGTGCGGTCACTACGGGTGCGGCGGCGTGCGTGCATC
GCTGCTGCCGCCGCCCGCCGACCTGCCACACGTCGCGCGCCGCATCGCGCCGCTCTGCGCACTCGCGCGGCGCCATCGCG
ACACGCTCGACGGGCTCGACGACATGGCCGCCGCCGACCGCCTCGCCGAGCTGAACGTGCTCGAACAGGTGCGGCTGCTG
CGCGCGTCGCCGATCGTGCGCGGCCGCGAGCGGCCACCGCTCGTGCATGGCTGGATCTTTTCGCTCGCCGACGGCCGCCT
GAAGGAGCTCGATTCCGGCTATGCGGCGTCGCCGACCGAAGCCGAGCCCGAGCCCGAGCGCGCTGCCGCCGTCGCGCTCG
GTTGA

Upstream 100 bases:

>100_bases
ACCCCTAATATCAGTCGAAAATCCAACCTTTCAATTTAGAAAGCATGCGATTGCGCCATTTCGTTCGATATTTATTTGCC
TTTATCAAAAAGGAGTCCTC

Downstream 100 bases:

>100_bases
CCCGCGCCCTGCCCCTCCACGCCAACGAAACCACCCCAACCATGAAACTGAACGAGCGCCTATCCACCCTGCCGCGCGAC
ATCGTCGCCGGCATCGTCGT

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MNRPKSMLVANIAWARETREHTPGFFDALARGQNPRVLWIGCADSRVPAETITHCAPGELFVHRNIANLFHPDDDNSASV
LEYAVRVLKVDHVIVCGHYGCGGVRASLLPPPADLPHVARRIAPLCALARRHRDTLDGLDDMAAADRLAELNVLEQVRLL
RASPIVRGRERPPLVHGWIFSLADGRLKELDSGYAASPTEAEPEPERAAAVALG

Sequences:

>Translated_214_residues
MNRPKSMLVANIAWARETREHTPGFFDALARGQNPRVLWIGCADSRVPAETITHCAPGELFVHRNIANLFHPDDDNSASV
LEYAVRVLKVDHVIVCGHYGCGGVRASLLPPPADLPHVARRIAPLCALARRHRDTLDGLDDMAAADRLAELNVLEQVRLL
RASPIVRGRERPPLVHGWIFSLADGRLKELDSGYAASPTEAEPEPERAAAVALG
>Mature_214_residues
MNRPKSMLVANIAWARETREHTPGFFDALARGQNPRVLWIGCADSRVPAETITHCAPGELFVHRNIANLFHPDDDNSASV
LEYAVRVLKVDHVIVCGHYGCGGVRASLLPPPADLPHVARRIAPLCALARRHRDTLDGLDDMAAADRLAELNVLEQVRLL
RASPIVRGRERPPLVHGWIFSLADGRLKELDSGYAASPTEAEPEPERAAAVALG

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=194, Percent_Identity=43.8144329896907, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI1786534, Length=198, Percent_Identity=31.8181818181818, Blast_Score=89, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6324292, Length=203, Percent_Identity=29.5566502463054, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 23390; Mature: 23390

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRPKSMLVANIAWARETREHTPGFFDALARGQNPRVLWIGCADSRVPAETITHCAPGEL
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEEECCCCCCCHHHHHCCCCCCE
FVHRNIANLFHPDDDNSASVLEYAVRVLKVDHVIVCGHYGCGGVRASLLPPPADLPHVAR
EEECCHHHHCCCCCCCHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCCCCHHHHHH
RIAPLCALARRHRDTLDGLDDMAAADRLAELNVLEQVRLLRASPIVRGRERPPLVHGWIF
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
SLADGRLKELDSGYAASPTEAEPEPERAAAVALG
HHCCCHHHHHCCCCCCCCCCCCCCHHHHHEECCC
>Mature Secondary Structure
MNRPKSMLVANIAWARETREHTPGFFDALARGQNPRVLWIGCADSRVPAETITHCAPGEL
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEEECCCCCCCHHHHHCCCCCCE
FVHRNIANLFHPDDDNSASVLEYAVRVLKVDHVIVCGHYGCGGVRASLLPPPADLPHVAR
EEECCHHHHCCCCCCCHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCCCCHHHHHH
RIAPLCALARRHRDTLDGLDDMAAADRLAELNVLEQVRLLRASPIVRGRERPPLVHGWIF
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
SLADGRLKELDSGYAASPTEAEPEPERAAAVALG
HHCCCHHHHHCCCCCCCCCCCCCCHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]