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The map label for this gene is lolC [H]

Identifier: 116690135

GI number: 116690135

Start: 2345948

End: 2347201

Strand: Reverse

Name: lolC [H]

Synonym: Bcen2424_2114

Alternate gene names: 116690135

Gene position: 2347201-2345948 (Counterclockwise)

Preceding gene: 116690141

Following gene: 116690134

Centisome position: 67.37

GC content: 66.75

Gene sequence:

>1254_bases
TTGAAACTTCCGTACGAATGGCAGATCGGCTGGCGCTACACGCGCGCCGGCAAACGCACGACCGGCAACGGCTTCATTTC
CTTCATCGCGCTCGTCTCGATGCTCGGGATCGCGCTCGGCGTCGCGGCGCTGATCGTCGTGCTGTCGGTGATGAACGGCT
TCCAGAAGGAAGTGCGCGACCGCATGCTGTCGGTGCTCGCGCACGTCGAGGTATTCTCGCCGACGGGGTCGATGCCCGAC
TGGCAACTGACCGCGCAGGAAGCGCGCCGCAATCCGTCGGTGATCGGCGCCGCGCCGTACGTCGACGCGCAGGCGCTGCT
CACGCGCCAGGACGCCGTGAGCGGCGTGATGCTGCGCGGCGTCGAGCCGTCGCTCGAGCCGCAGGTGTCCGACATCGGCA
AGGACATGAAGGCCGGCCAGCTCGGCGCGCTCGTGCCGGGCCAGTTCGGCATCGTGCTCGGCGACGCGCTCGCCGGCAAC
CTCGGCGTGACGGTCGGCGACAAGGTCACGCTCGTCGCGCCCGAAGGCTCGATCACGCCGGCCGGGATGATGCCGCGCCT
GAAGCAGTTCACGGTGGTCGGCGTGTTCGAGTCGGGCCACTACGAATACGACAGCACGCTCGCGATGATCAACATCCGCG
ACGCCGAGGCGCTGTTCCGGATGAGCGCGCCGACCGGCGTGCGGCTGCGGCTCACCGATATGCAGAAGGCGCCGCAAGTC
GCGGTCGAGCTGTCGCATACGCTGTCGGGCAGCCTGTACATTCGCGACTGGACCCAGCAGAACAAGACGTGGTTCTCGGC
CGTGCAGATCGAGAAGCGGATGATGTTCATCATCCTCACGCTGATCATCGCGGTGGCCGCGTTCAACCTCGTGTCGTCGC
TCGTGATGACGGTGACCAACAAGCAGGCCGACATCGCGATCCTGCGCACGCTCGGCGCGCAGCCGGGGTCGATCATGAAG
ATCTTCGTCGTGCAGGGCGTGACGATCGGCTTCGTCGGCACCGCGTCCGGCGTCGCGCTCGGCTGCCTGATCGCGTGGAG
CATCCCGTGGCTGATCCCGATGATCGAGCACCTGTTCGGCGTGCAGTTCCTGCCGCCGTCGGTGTATTTCATCAGCGAGC
TACCGTCCGAACTCGTCGCGAGCGACGTGATCCGGATCGGGCTGATCGCGTTCGCGCTGTCGGCCGTCGCGACGCTTTAT
CCGAGCTGGCGCGGCGCGAAGGTGAAGCCGGCGGAGGCGCTCCGCTATGAATGA

Upstream 100 bases:

>100_bases
TCCGGCGGCCGTTTTTCGACCGTGCCCGGGCTGCCGGCCGCCGCCCGGCGGCGGTCCGGCCGCGGCGCGCCTCCCGCCGT
AACCAGCAGAAAGGATTCGC

Downstream 100 bases:

>100_bases
CCGCGCGGCCGCATTCGCGGATTCACGACAACAACACAACAGACAGGATTCGGCAGGTATGCAGGAATACGTGCTTCAGG
CGCGCGGGATCACGAAGGCG

Product: LolC/E family lipoprotein releasing system, transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MKLPYEWQIGWRYTRAGKRTTGNGFISFIALVSMLGIALGVAALIVVLSVMNGFQKEVRDRMLSVLAHVEVFSPTGSMPD
WQLTAQEARRNPSVIGAAPYVDAQALLTRQDAVSGVMLRGVEPSLEPQVSDIGKDMKAGQLGALVPGQFGIVLGDALAGN
LGVTVGDKVTLVAPEGSITPAGMMPRLKQFTVVGVFESGHYEYDSTLAMINIRDAEALFRMSAPTGVRLRLTDMQKAPQV
AVELSHTLSGSLYIRDWTQQNKTWFSAVQIEKRMMFIILTLIIAVAAFNLVSSLVMTVTNKQADIAILRTLGAQPGSIMK
IFVVQGVTIGFVGTASGVALGCLIAWSIPWLIPMIEHLFGVQFLPPSVYFISELPSELVASDVIRIGLIAFALSAVATLY
PSWRGAKVKPAEALRYE

Sequences:

>Translated_417_residues
MKLPYEWQIGWRYTRAGKRTTGNGFISFIALVSMLGIALGVAALIVVLSVMNGFQKEVRDRMLSVLAHVEVFSPTGSMPD
WQLTAQEARRNPSVIGAAPYVDAQALLTRQDAVSGVMLRGVEPSLEPQVSDIGKDMKAGQLGALVPGQFGIVLGDALAGN
LGVTVGDKVTLVAPEGSITPAGMMPRLKQFTVVGVFESGHYEYDSTLAMINIRDAEALFRMSAPTGVRLRLTDMQKAPQV
AVELSHTLSGSLYIRDWTQQNKTWFSAVQIEKRMMFIILTLIIAVAAFNLVSSLVMTVTNKQADIAILRTLGAQPGSIMK
IFVVQGVTIGFVGTASGVALGCLIAWSIPWLIPMIEHLFGVQFLPPSVYFISELPSELVASDVIRIGLIAFALSAVATLY
PSWRGAKVKPAEALRYE
>Mature_417_residues
MKLPYEWQIGWRYTRAGKRTTGNGFISFIALVSMLGIALGVAALIVVLSVMNGFQKEVRDRMLSVLAHVEVFSPTGSMPD
WQLTAQEARRNPSVIGAAPYVDAQALLTRQDAVSGVMLRGVEPSLEPQVSDIGKDMKAGQLGALVPGQFGIVLGDALAGN
LGVTVGDKVTLVAPEGSITPAGMMPRLKQFTVVGVFESGHYEYDSTLAMINIRDAEALFRMSAPTGVRLRLTDMQKAPQV
AVELSHTLSGSLYIRDWTQQNKTWFSAVQIEKRMMFIILTLIIAVAAFNLVSSLVMTVTNKQADIAILRTLGAQPGSIMK
IFVVQGVTIGFVGTASGVALGCLIAWSIPWLIPMIEHLFGVQFLPPSVYFISELPSELVASDVIRIGLIAFALSAVATLY
PSWRGAKVKPAEALRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=416, Percent_Identity=33.6538461538462, Blast_Score=221, Evalue=5e-59,
Organism=Escherichia coli, GI1787360, Length=421, Percent_Identity=36.8171021377672, Blast_Score=205, Evalue=4e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45070; Mature: 45070

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLPYEWQIGWRYTRAGKRTTGNGFISFIALVSMLGIALGVAALIVVLSVMNGFQKEVRD
CCCCCEEEECEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMLSVLAHVEVFSPTGSMPDWQLTAQEARRNPSVIGAAPYVDAQALLTRQDAVSGVMLRG
HHHHHHHHHHEECCCCCCCCCEEEHHHHCCCCCEEECCCCCCHHHHHHHHHHHCCCEEEC
VEPSLEPQVSDIGKDMKAGQLGALVPGQFGIVLGDALAGNLGVTVGDKVTLVAPEGSITP
CCCCCCCCHHHHCCCCCCCCCCCCCCCCCCEEEECHHCCCCCEEECCEEEEECCCCCCCC
AGMMPRLKQFTVVGVFESGHYEYDSTLAMINIRDAEALFRMSAPTGVRLRLTDMQKAPQV
CCCCCHHHHEEEEEEEECCCEECCCEEEEEEECCHHHHHEECCCCCEEEEECCCCCCCHH
AVELSHTLSGSLYIRDWTQQNKTWFSAVQIEKRMMFIILTLIIAVAAFNLVSSLVMTVTN
HHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KQADIAILRTLGAQPGSIMKIFVVQGVTIGFVGTASGVALGCLIAWSIPWLIPMIEHLFG
CCHHHHHHHHHCCCCCCEEEEEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHC
VQFLPPSVYFISELPSELVASDVIRIGLIAFALSAVATLYPSWRGAKVKPAEALRYE
CCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCC
>Mature Secondary Structure
MKLPYEWQIGWRYTRAGKRTTGNGFISFIALVSMLGIALGVAALIVVLSVMNGFQKEVRD
CCCCCEEEECEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMLSVLAHVEVFSPTGSMPDWQLTAQEARRNPSVIGAAPYVDAQALLTRQDAVSGVMLRG
HHHHHHHHHHEECCCCCCCCCEEEHHHHCCCCCEEECCCCCCHHHHHHHHHHHCCCEEEC
VEPSLEPQVSDIGKDMKAGQLGALVPGQFGIVLGDALAGNLGVTVGDKVTLVAPEGSITP
CCCCCCCCHHHHCCCCCCCCCCCCCCCCCCEEEECHHCCCCCEEECCEEEEECCCCCCCC
AGMMPRLKQFTVVGVFESGHYEYDSTLAMINIRDAEALFRMSAPTGVRLRLTDMQKAPQV
CCCCCHHHHEEEEEEEECCCEECCCEEEEEEECCHHHHHEECCCCCEEEEECCCCCCCHH
AVELSHTLSGSLYIRDWTQQNKTWFSAVQIEKRMMFIILTLIIAVAAFNLVSSLVMTVTN
HHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KQADIAILRTLGAQPGSIMKIFVVQGVTIGFVGTASGVALGCLIAWSIPWLIPMIEHLFG
CCHHHHHHHHHCCCCCCEEEEEEECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHC
VQFLPPSVYFISELPSELVASDVIRIGLIAFALSAVATLYPSWRGAKVKPAEALRYE
CCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]