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The map label for this gene is moaE [H]

Identifier: 116689871

GI number: 116689871

Start: 2055122

End: 2055598

Strand: Reverse

Name: moaE [H]

Synonym: Bcen2424_1850

Alternate gene names: 116689871

Gene position: 2055598-2055122 (Counterclockwise)

Preceding gene: 116689872

Following gene: 116689869

Centisome position: 59.0

GC content: 67.92

Gene sequence:

>477_bases
ATGGCGACGATACGAGTCCAGACCGACGATTTCGACCTGAATGCCGAAGTGGCGGCATTGCGTGCGCGCAACCCGAAGAT
CGGTGCGCTCGCGTGCTTCGTCGGCACGGTGCGCGACCTGAACGAAGGCGATGCGGTCGCCGCGATGGAGCTCGAGCACT
ATCCCGGCATGACCGAGAAGGCGCTCGAGCGGATCGCGGCCGAGGCCGGCCGGCGCTGGCCGGGCATCGACGTCGCGATC
GTGCATCGCGTCGGCAGGCTGCTGCCGCTCGACCAGATCGTGATGGTCGCGACGGTCGCGTCGCACCGCGGCGATGCATT
CGCGTCGTGCGAATTCGTGATGGACTATCTGAAGACCGAAGCGCCGTTCTGGAAGAAGGAAACGACGCCGGACGGCGAGC
GCTGGGTCGATGCGCGCAGTACCGACGACGCCGCGCTCGCGCGCTGGGGCGTCGAGTCGGGCAACACGCCGCGCTGA

Upstream 100 bases:

>100_bases
ATGGCGTGCAACCACGAGATGACCGATCCCGACACGCGGCTCACCGAGGGCTGCGAGGTCGCGTTCTTCCCGCCGGTGAC
GGGTGGTTGAGGCGGCTGTC

Downstream 100 bases:

>100_bases
GCTGAGCGCGGCGCGCGGGCGGTGCGGCGATGTGTCGCATGCGCGCCGGTGTCGCACACGACGGGCGTTACGCGTCCGGG
TCGATGCCGCGCCCGATGAT

Product: molybdopterin biosynthesis MoaE

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MATIRVQTDDFDLNAEVAALRARNPKIGALACFVGTVRDLNEGDAVAAMELEHYPGMTEKALERIAAEAGRRWPGIDVAI
VHRVGRLLPLDQIVMVATVASHRGDAFASCEFVMDYLKTEAPFWKKETTPDGERWVDARSTDDAALARWGVESGNTPR

Sequences:

>Translated_158_residues
MATIRVQTDDFDLNAEVAALRARNPKIGALACFVGTVRDLNEGDAVAAMELEHYPGMTEKALERIAAEAGRRWPGIDVAI
VHRVGRLLPLDQIVMVATVASHRGDAFASCEFVMDYLKTEAPFWKKETTPDGERWVDARSTDDAALARWGVESGNTPR
>Mature_157_residues
ATIRVQTDDFDLNAEVAALRARNPKIGALACFVGTVRDLNEGDAVAAMELEHYPGMTEKALERIAAEAGRRWPGIDVAIV
HRVGRLLPLDQIVMVATVASHRGDAFASCEFVMDYLKTEAPFWKKETTPDGERWVDARSTDDAALARWGVESGNTPR

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=113, Percent_Identity=32.7433628318584, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1787003, Length=146, Percent_Identity=50.6849315068493, Blast_Score=151, Evalue=2e-38,
Organism=Drosophila melanogaster, GI21356259, Length=128, Percent_Identity=32.8125, Blast_Score=73, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 17369; Mature: 17238

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00018 EF_HAND_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIRVQTDDFDLNAEVAALRARNPKIGALACFVGTVRDLNEGDAVAAMELEHYPGMTEK
CCEEEEECCCCCCCHHHHEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEEHHHCCCCHHH
ALERIAAEAGRRWPGIDVAIVHRVGRLLPLDQIVMVATVASHRGDAFASCEFVMDYLKTE
HHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
APFWKKETTPDGERWVDARSTDDAALARWGVESGNTPR
CCCCCCCCCCCHHHEECCCCCCHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ATIRVQTDDFDLNAEVAALRARNPKIGALACFVGTVRDLNEGDAVAAMELEHYPGMTEK
CEEEEECCCCCCCHHHHEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEEHHHCCCCHHH
ALERIAAEAGRRWPGIDVAIVHRVGRLLPLDQIVMVATVASHRGDAFASCEFVMDYLKTE
HHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
APFWKKETTPDGERWVDARSTDDAALARWGVESGNTPR
CCCCCCCCCCCHHHEECCCCCCHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]