Click here to switch to the map view.

The map label for this gene is clpB [H]

Identifier: 116689868

GI number: 116689868

Start: 2050984

End: 2053581

Strand: Reverse

Name: clpB [H]

Synonym: Bcen2424_1847

Alternate gene names: 116689868

Gene position: 2053581-2050984 (Counterclockwise)

Preceding gene: 116689869

Following gene: 116689865

Centisome position: 58.94

GC content: 65.67

Gene sequence:

>2598_bases
ATGAGAATCGACAAGCTCACCACCAAGTTCCAGGAAGCACTCGCGGACGCGCAAAGCCTCGCGGCAGGCCGCGACAATCA
ATACATCGAACCCGTTCACGTGCTCGCGGCACTGGTCGCGCAGCAGGACGGCTCTGCCCGCTCGCTGATGTCGCGCGCGG
GCGTTCACGTGCAGGCGCTGCAAGGCGCGCTGAACGAAGCCATTTCGCGCCTGCCGCAAGTGACGGGCACGGGCGGCGAC
ATCCAGATCGGCCGTGAACTCGCCGGGCTGCTGAACCAGGCCGACAAGGAAGCGCAGAAGCTCAACGACACGTTCATCGC
GAGCGAGATGTTCCTGCTCGCCGTGTCCGACGACAAGGGCGACGCCGGCAAGCTCGCGCGCCAGCACGGCCTCACGCGCA
AGTCGCTCGAAGCCGCGATCGCCGCGGTGCGCGGCGGCTCGCAGGTGCACAGCCAGGATGCGGAAAGCCAGCGCGAGGCG
CTGAAGAAATACACGGTCGACCTGACCGAGCGCGCCCGCGCGGGCAAGCTCGATCCGGTGATCGGCCGCGACGACGAAAT
CCGTCGCTCGATCCAGATCCTGCAGCGCCGCACCAAGAACAACCCGGTGCTGATCGGCGAGCCGGGCGTCGGCAAGACCG
CGATCGTCGAAGGGCTCGCGCAGCGGATCGTCAACGGCGAAGTGCCCGAGACGCTGAAGGGCAAGCGCGTGCTGTCGCTC
GACATGGCCGCGCTGCTCGCCGGCGCGAAGTATCGCGGCGAGTTCGAGGAGCGCCTGAAGGCGGTGCTCAACGACATCGC
GAAGGACGAAGGCCAGACGATCGTCTTCATCGACGAAATCCACACGATGGTCGGCGCGGGCAAGGCCGAAGGCGCGATGG
ATGCAGGCAACATGCTGAAGCCGGCGCTGTCGCGCGGCGAACTGCACTGCATCGGCGCGACCACGCTCGACGAATACCGC
AAGTACATCGAGAAGGACGCCGCGCTCGAACGGCGCTTCCAGAAGGTGCTCGTCGACGAGCCGAGCGTCGAGGCGACGAT
CGCGATCCTGCGCGGGCTGCAGGAGAAGTACGAACTGCACCACGGTGTCGACATCACCGACCCGGCGATCGTCGCCGCGG
CCGAGCTGTCGCATCGCTACATCACCGACCGCTTCTTGCCCGACAAGGCCATCGACCTGATCGACGAAGCCGCTTCGAAG
ATCAAGATGGAAATCGATTCGAAGCCCGAAGAGATGGACAAGCTCGACCGTCGTCTGATCCAGCTGAAGATCGAGCGCGA
AGCCGTGAAGAAGGAGCAGGACGAAGCGTCGCAGAAGCGCCTGCAGCTGATCGAGGAAGAGATCGACCGCCTCGGCCGCG
AATATGCGGACCTGGAAGAGATCTGGACCGCCGAGAAGGCCGCGGTGCAGGGCAGCGCGCAGCTCAAGGAAGAGATCGAG
AAGGTGCGGGCGGATATCGCGCGCCTGCAGCGTGAAGGCAAGCTCGAGAAGGTCGCCGAGCTGCAGTACGGCAAGCTGCC
GCAGCTCGAGGCCCAGCTGAAGCAGGTCACGCAGGCCGAAGAGCAGGAGCAGCACAACCCGACGCGTCCGCGCCTGCTGC
GCACGCAGGTCGGCGCCGAGGAAATCGCGGAAGTCGTGTCGCGTTCGACGGGCATTCCCGTGTCGCGGATGATGCAGGGC
GAACGCGAGAAGCTGCTGCACATCGAGGAAAAGCTGCACGAGCGCGTGGTCGGCCAGGACGAGGCGATCAGCGCGGTGGC
GGACGCGATCCGTCGTTCGCGCGCGGGTCTCGCCGATCCGAACCGTCCGTACGGCTCGTTCCTGTTCCTCGGCCCGACGG
GGGTCGGCAAGACCGAGCTGTGCAAGGCGCTGGCGTCGTTCCTGTTCGATTCGGAAGAGCATCTGATCCGCATCGACATG
AGCGAGTTCATGGAGAAGCACAGTGTCGCGCGGTTGATCGGCGCGCCGCCGGGCTACGTCGGCTACGAGGAAGGCGGTTA
CCTGACGGAAGCCGTGCGTCGCAAGCCGTACAGCGTGATCCTGCTCGACGAGATCGAGAAGGCGCATCCGGACGTGTTCA
ACGTGCTGCTGCAGGTGCTCGACGACGGCCGCATGACGGACGGGCAGGGGCGCACGGTCGACTTCAAGAACACGGTCATC
GTGATGACGTCGAACCTCGGCTCGCAGGTGATTCAGGCGATGACGGGCGCGCCGCAGGACGAGATCAAGGACGCGGTGTG
GCTCGAGGTGAAGCAGCATTTCCGCCCCGAGTTCCTGAACCGGATCGACGACGTCGTGGTGTTCCATGCGCTCGACCGCA
GCAACATCGAGTCGATCGCGAAGATCCAGCTGGCGCGCCTGCACGACCGGCTCGCGAAGCTCGACATGGCGCTCGACGTG
TCGCCCGCGGCGCTCGAACAGATCGCGAAGGTCGGCTACGATCCGGTGTTCGGTGCGCGGCCGCTGAAGCGCGCGATCCA
GCAGGAGATCGAGAACCCGGTCGCGAAGCTGATCCTCGCCGGCCGCTTCGGTCCGAAGGACGTGATCCCGGTCGACGTCA
ACGACGGCCAGTTCGTGTTCGACCGCGTCGTGCACTGA

Upstream 100 bases:

>100_bases
CGATCCGGCAATTTTTGCGCTGAATCAACCCGAATTTCGCTTGAAAGCCGCATAACCATCCTCATCTTGGTGTTAATCGA
AAATTGGAGGTCTCGACTAA

Downstream 100 bases:

>100_bases
TCGCCTGCCATCGGCAGCGTGCCCGGTTCGCACCGGGCGCAAAAACAAACACCCCGCCTCGGCGGGGTGTTTGCATATGG
AGCGGCCGAAACCGCTATGC

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 865; Mature: 865

Protein sequence:

>865_residues
MRIDKLTTKFQEALADAQSLAAGRDNQYIEPVHVLAALVAQQDGSARSLMSRAGVHVQALQGALNEAISRLPQVTGTGGD
IQIGRELAGLLNQADKEAQKLNDTFIASEMFLLAVSDDKGDAGKLARQHGLTRKSLEAAIAAVRGGSQVHSQDAESQREA
LKKYTVDLTERARAGKLDPVIGRDDEIRRSIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPETLKGKRVLSL
DMAALLAGAKYRGEFEERLKAVLNDIAKDEGQTIVFIDEIHTMVGAGKAEGAMDAGNMLKPALSRGELHCIGATTLDEYR
KYIEKDAALERRFQKVLVDEPSVEATIAILRGLQEKYELHHGVDITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAASK
IKMEIDSKPEEMDKLDRRLIQLKIEREAVKKEQDEASQKRLQLIEEEIDRLGREYADLEEIWTAEKAAVQGSAQLKEEIE
KVRADIARLQREGKLEKVAELQYGKLPQLEAQLKQVTQAEEQEQHNPTRPRLLRTQVGAEEIAEVVSRSTGIPVSRMMQG
EREKLLHIEEKLHERVVGQDEAISAVADAIRRSRAGLADPNRPYGSFLFLGPTGVGKTELCKALASFLFDSEEHLIRIDM
SEFMEKHSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEIEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVI
VMTSNLGSQVIQAMTGAPQDEIKDAVWLEVKQHFRPEFLNRIDDVVVFHALDRSNIESIAKIQLARLHDRLAKLDMALDV
SPAALEQIAKVGYDPVFGARPLKRAIQQEIENPVAKLILAGRFGPKDVIPVDVNDGQFVFDRVVH

Sequences:

>Translated_865_residues
MRIDKLTTKFQEALADAQSLAAGRDNQYIEPVHVLAALVAQQDGSARSLMSRAGVHVQALQGALNEAISRLPQVTGTGGD
IQIGRELAGLLNQADKEAQKLNDTFIASEMFLLAVSDDKGDAGKLARQHGLTRKSLEAAIAAVRGGSQVHSQDAESQREA
LKKYTVDLTERARAGKLDPVIGRDDEIRRSIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPETLKGKRVLSL
DMAALLAGAKYRGEFEERLKAVLNDIAKDEGQTIVFIDEIHTMVGAGKAEGAMDAGNMLKPALSRGELHCIGATTLDEYR
KYIEKDAALERRFQKVLVDEPSVEATIAILRGLQEKYELHHGVDITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAASK
IKMEIDSKPEEMDKLDRRLIQLKIEREAVKKEQDEASQKRLQLIEEEIDRLGREYADLEEIWTAEKAAVQGSAQLKEEIE
KVRADIARLQREGKLEKVAELQYGKLPQLEAQLKQVTQAEEQEQHNPTRPRLLRTQVGAEEIAEVVSRSTGIPVSRMMQG
EREKLLHIEEKLHERVVGQDEAISAVADAIRRSRAGLADPNRPYGSFLFLGPTGVGKTELCKALASFLFDSEEHLIRIDM
SEFMEKHSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEIEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVI
VMTSNLGSQVIQAMTGAPQDEIKDAVWLEVKQHFRPEFLNRIDDVVVFHALDRSNIESIAKIQLARLHDRLAKLDMALDV
SPAALEQIAKVGYDPVFGARPLKRAIQQEIENPVAKLILAGRFGPKDVIPVDVNDGQFVFDRVVH
>Mature_865_residues
MRIDKLTTKFQEALADAQSLAAGRDNQYIEPVHVLAALVAQQDGSARSLMSRAGVHVQALQGALNEAISRLPQVTGTGGD
IQIGRELAGLLNQADKEAQKLNDTFIASEMFLLAVSDDKGDAGKLARQHGLTRKSLEAAIAAVRGGSQVHSQDAESQREA
LKKYTVDLTERARAGKLDPVIGRDDEIRRSIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPETLKGKRVLSL
DMAALLAGAKYRGEFEERLKAVLNDIAKDEGQTIVFIDEIHTMVGAGKAEGAMDAGNMLKPALSRGELHCIGATTLDEYR
KYIEKDAALERRFQKVLVDEPSVEATIAILRGLQEKYELHHGVDITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAASK
IKMEIDSKPEEMDKLDRRLIQLKIEREAVKKEQDEASQKRLQLIEEEIDRLGREYADLEEIWTAEKAAVQGSAQLKEEIE
KVRADIARLQREGKLEKVAELQYGKLPQLEAQLKQVTQAEEQEQHNPTRPRLLRTQVGAEEIAEVVSRSTGIPVSRMMQG
EREKLLHIEEKLHERVVGQDEAISAVADAIRRSRAGLADPNRPYGSFLFLGPTGVGKTELCKALASFLFDSEEHLIRIDM
SEFMEKHSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEIEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVI
VMTSNLGSQVIQAMTGAPQDEIKDAVWLEVKQHFRPEFLNRIDDVVVFHALDRSNIESIAKIQLARLHDRLAKLDMALDV
SPAALEQIAKVGYDPVFGARPLKRAIQQEIENPVAKLILAGRFGPKDVIPVDVNDGQFVFDRVVH

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=298, Percent_Identity=36.241610738255, Blast_Score=196, Evalue=7e-50,
Organism=Escherichia coli, GI1788943, Length=860, Percent_Identity=66.6279069767442, Blast_Score=1170, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=398, Percent_Identity=41.4572864321608, Blast_Score=283, Evalue=4e-77,
Organism=Saccharomyces cerevisiae, GI6320464, Length=712, Percent_Identity=52.3876404494382, Blast_Score=753, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=865, Percent_Identity=42.5433526011561, Blast_Score=687, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 95881; Mature: 95881

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIDKLTTKFQEALADAQSLAAGRDNQYIEPVHVLAALVAQQDGSARSLMSRAGVHVQAL
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCHHHHH
QGALNEAISRLPQVTGTGGDIQIGRELAGLLNQADKEAQKLNDTFIASEMFLLAVSDDKG
HHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCC
DAGKLARQHGLTRKSLEAAIAAVRGGSQVHSQDAESQREALKKYTVDLTERARAGKLDPV
CHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
IGRDDEIRRSIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPETLKGKRVLSL
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCHHCCCEEHHH
DMAALLAGAKYRGEFEERLKAVLNDIAKDEGQTIVFIDEIHTMVGAGKAEGAMDAGNMLK
HHHHHHHCCHHCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCCHHHH
PALSRGELHCIGATTLDEYRKYIEKDAALERRFQKVLVDEPSVEATIAILRGLQEKYELH
HHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
HGVDITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAASKIKMEIDSKPEEMDKLDRRLI
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEHHCCCCHHHHHHHHHHHH
QLKIEREAVKKEQDEASQKRLQLIEEEIDRLGREYADLEEIWTAEKAAVQGSAQLKEEIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
KVRADIARLQREGKLEKVAELQYGKLPQLEAQLKQVTQAEEQEQHNPTRPRLLRTQVGAE
HHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHH
EIAEVVSRSTGIPVSRMMQGEREKLLHIEEKLHERVVGQDEAISAVADAIRRSRAGLADP
HHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
NRPYGSFLFLGPTGVGKTELCKALASFLFDSEEHLIRIDMSEFMEKHSVARLIGAPPGYV
CCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCC
GYEEGGYLTEAVRRKPYSVILLDEIEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVI
CCCCCCHHHHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEE
VMTSNLGSQVIQAMTGAPQDEIKDAVWLEVKQHFRPEFLNRIDDVVVFHALDRSNIESIA
EEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHH
KIQLARLHDRLAKLDMALDVSPAALEQIAKVGYDPVFGARPLKRAIQQEIENPVAKLILA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GRFGPKDVIPVDVNDGQFVFDRVVH
CCCCCCCEEEEECCCCCHHHHHHCC
>Mature Secondary Structure
MRIDKLTTKFQEALADAQSLAAGRDNQYIEPVHVLAALVAQQDGSARSLMSRAGVHVQAL
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCHHHHH
QGALNEAISRLPQVTGTGGDIQIGRELAGLLNQADKEAQKLNDTFIASEMFLLAVSDDKG
HHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCC
DAGKLARQHGLTRKSLEAAIAAVRGGSQVHSQDAESQREALKKYTVDLTERARAGKLDPV
CHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
IGRDDEIRRSIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPETLKGKRVLSL
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCHHCCCEEHHH
DMAALLAGAKYRGEFEERLKAVLNDIAKDEGQTIVFIDEIHTMVGAGKAEGAMDAGNMLK
HHHHHHHCCHHCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCCHHHH
PALSRGELHCIGATTLDEYRKYIEKDAALERRFQKVLVDEPSVEATIAILRGLQEKYELH
HHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
HGVDITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAASKIKMEIDSKPEEMDKLDRRLI
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEHHCCCCHHHHHHHHHHHH
QLKIEREAVKKEQDEASQKRLQLIEEEIDRLGREYADLEEIWTAEKAAVQGSAQLKEEIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
KVRADIARLQREGKLEKVAELQYGKLPQLEAQLKQVTQAEEQEQHNPTRPRLLRTQVGAE
HHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHH
EIAEVVSRSTGIPVSRMMQGEREKLLHIEEKLHERVVGQDEAISAVADAIRRSRAGLADP
HHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
NRPYGSFLFLGPTGVGKTELCKALASFLFDSEEHLIRIDMSEFMEKHSVARLIGAPPGYV
CCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCC
GYEEGGYLTEAVRRKPYSVILLDEIEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVI
CCCCCCHHHHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEE
VMTSNLGSQVIQAMTGAPQDEIKDAVWLEVKQHFRPEFLNRIDDVVVFHALDRSNIESIA
EEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHH
KIQLARLHDRLAKLDMALDVSPAALEQIAKVGYDPVFGARPLKRAIQQEIENPVAKLILA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GRFGPKDVIPVDVNDGQFVFDRVVH
CCCCCCCEEEEECCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]