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The map label for this gene is dnaX [H]

Identifier: 116689848

GI number: 116689848

Start: 2028382

End: 2030745

Strand: Reverse

Name: dnaX [H]

Synonym: Bcen2424_1827

Alternate gene names: 116689848

Gene position: 2030745-2028382 (Counterclockwise)

Preceding gene: 116689857

Following gene: 116689847

Centisome position: 58.29

GC content: 71.28

Gene sequence:

>2364_bases
ATGACCTATCAAGTTCTCGCACGCAAGTGGCGTCCGAAGGATTTCGCTTCGCTCGTCGGCCAGGAGCACGTCGTCAGGGC
GCTCACGCACGCGCTCGACGGCGAGCGTCTCCATCACGCCTATCTGTTTACCGGAACCCGCGGTGTCGGCAAGACGACGC
TGTCGCGGATCTTCGCGAAGGCGCTCAACTGTGAAACCGGCGTCACGTCGCAGCCGTGCGGCGTGTGTCGTGCCTGTCGC
GAGATCGACGAGGGCCGTTTCGTCGATTACGTCGAGATGGACGCGGCGAGCAATCGCGGCGTCGATGAAATGGCCGCGCT
GCTCGAGCGCGCGGTGTACGCGCCCGTCGATGCGCGCTTCAAGGTCTACATGATCGACGAAGTGCACATGCTGACGAATC
ACGCGTTCAACGCGATGCTGAAGACGCTCGAAGAGCCGCCGCCGCACGTCAAGTTCATCCTCGCGACGACCGATCCGCAG
AAAATCCCCGTGACTGTGCTGTCGCGCTGCCTGCAGTTCAACCTGAAGCAGATGCCGGCCGGGCACATCGTGTCGCATCT
CGAGCGGATCCTCGGCGAAGAGCAGATCACGTTCGAGCCGCAGGCGCTGCGCCTGCTCGCGCGCGCCGCGCAGGGCAGCA
TGCGCGACGCGCTGTCCCTGACCGACCAGGCGATCGCCTATTCGGCGAACGAGGTGACCGAGTCGGCGGTGTCGGGCATG
CTCGGCGCGCTCGACCAGACATACATGGTGCGCCTGCTCGACGCGCTCGCGGCGGCCAATGGCCCGGAAATCCTCGCGAT
TGCCGACGAGATGTCGTTGCGCAGCCTGTCGTTCTCGACCGCGCTGCAGGATCTCGCGAGCCTGCTGCACCGGATCGCCT
GGGCGCAGTTCGCGCCGGGCTCGGTGCTCGACGAATGGCCGGAAGCGGCCGACCTGCGTCGTTTTGCGGAGACGCTGAGC
CCCGAGCAGGTGCAATTGTTCTATCAGATCGCGACGGTCGGGCGCGCCGAGCTTGGCCTTGCGCCCGACGAATACGCCGG
TTTCACGATGACGCTGCTGCGGATGCTCGCATTCGAGCCGGCCGTTGGCGCCGGCAGCGCGCCGGGCGGCCAGCCGTCCG
TGCCGCCGCGTGCGGTGCCGGCCCCGCGTGCTGCCGCGGCGAAGCCGGTGTCGGCCACGCCCGCCGGCGCAGCGCGTCCG
CAAGCTGCGGTGCCGGCTGCACCGGTTGCGCCGGTCGCCCGTTCGGCGCCCGCGCAGTCAAGCGATGAAGCCGAACGGCC
GGCCGCCAAGCCGCCTGCCGCCCAGTCACCGGCAGAGGCTGCAGCCTCGGTACCGACAGCGGTCGACGCACAAGCGATCG
AGGAGCCGTCGCAGCCGGAAACGAAGGCGGCGCCCGCTGGCGACGTGCCGCCTCCCGCCCGGAAGGAACCCGAGCCGCCT
GCCGTTGCCGCCGTGCAGCGAAACGACGAACCGGCTCCGCAGGCCGAACCGGCGCCGCGCGCCGCATCGCCCGAGCCGGC
CGCCGCACGGCCGGCGGCGCGCGCAGGCGGTGCCGCCGCCGCGCTCGACGTGCTGCGCAATGCGGGGATGCGCGTGTCGT
CGGACCGCGGCGGGCGCGCAGGCGCAACAGCCAAACCGGCGGCGGCCCAGCCGGCCGCCGAGAAGCCGGCCGCGCCGCGT
CCGGCCGTCCAGGTGCCGACGCCGCGTGCCGCTGCCCGCGCGCCGCAAGCAGCCGAGTCGCGCCAGCCGTCGCCGCCGTG
GGAAGACATCCCGCCCGACGACTACGTGCCGCTCAGCGCCGACGAAATGTTCGGCGGTTCCGACGACGGCTTCGTGCCGG
TGTTCGACAGCGGTCCCGACGATGTGCGCGTGACGCCGAAGCCGGCGGACGCGCGTCCGGCCGCGCCGATCGACACGCGG
CCGCTGCCGCCCGCGATCGCGCTCGATCCGATCGGCTTCGACGGCGAATGGCCGGCGCTCGCCGCACGGCTGCCGCTGAA
GGGCGTCGCGTACCAGCTCGCGTTCAACAGCGAGCTGACGGCCGTCGATGCGGGCACATTGAAACTGTCCGTGCCGGTGC
CGCAGTATGCGGACGCCGCGCAGGTGACGAAGCTGAAGGCCGCACTGGCCGATGCGCTCGGCAAGCCGGTCGAGGTGAGC
GTCGAGGTCGGGCCCGCACGGCGCACCGCGGCGGCGCTCGATGCGGCCGCGCGCGCGGCGCGCCAGCGCGAAGCCGAGCA
GGAGATTCACGGCGATCCGTTCGTCCAGCAGCTCGTGCGCGACTTCGGTGCGCGCATCGTCGAGGGGTCGGTGCGTCCGC
TCGCCGATTCGGCGCCGGACGGTGTGCCGCCCACACTCCATTGA

Upstream 100 bases:

>100_bases
TTTTTATTTCTGCGTCACACTCCGTTCGACCTGCCTCTTGCCCGTCTTCCGCACCGTTTCGCGTGTCGGCGCGACGCAGC
GTTACTGATACAATTTCCCG

Downstream 100 bases:

>100_bases
ACTGACCGCCCCGCGACAGGCACAATCACGCCCCGCACACATTGGCCGGCACGCGCCGCGTGCCGGTTTTCACACGATCA
AGAAGGAGTATTCCCATGTT

Product: DNA polymerase III subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 787; Mature: 786

Protein sequence:

>787_residues
MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGERLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR
EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ
KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGM
LGALDQTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLASLLHRIAWAQFAPGSVLDEWPEAADLRRFAETLS
PEQVQLFYQIATVGRAELGLAPDEYAGFTMTLLRMLAFEPAVGAGSAPGGQPSVPPRAVPAPRAAAAKPVSATPAGAARP
QAAVPAAPVAPVARSAPAQSSDEAERPAAKPPAAQSPAEAAASVPTAVDAQAIEEPSQPETKAAPAGDVPPPARKEPEPP
AVAAVQRNDEPAPQAEPAPRAASPEPAAARPAARAGGAAAALDVLRNAGMRVSSDRGGRAGATAKPAAAQPAAEKPAAPR
PAVQVPTPRAAARAPQAAESRQPSPPWEDIPPDDYVPLSADEMFGGSDDGFVPVFDSGPDDVRVTPKPADARPAAPIDTR
PLPPAIALDPIGFDGEWPALAARLPLKGVAYQLAFNSELTAVDAGTLKLSVPVPQYADAAQVTKLKAALADALGKPVEVS
VEVGPARRTAAALDAAARAARQREAEQEIHGDPFVQQLVRDFGARIVEGSVRPLADSAPDGVPPTLH

Sequences:

>Translated_787_residues
MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGERLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR
EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ
KIPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGM
LGALDQTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLASLLHRIAWAQFAPGSVLDEWPEAADLRRFAETLS
PEQVQLFYQIATVGRAELGLAPDEYAGFTMTLLRMLAFEPAVGAGSAPGGQPSVPPRAVPAPRAAAAKPVSATPAGAARP
QAAVPAAPVAPVARSAPAQSSDEAERPAAKPPAAQSPAEAAASVPTAVDAQAIEEPSQPETKAAPAGDVPPPARKEPEPP
AVAAVQRNDEPAPQAEPAPRAASPEPAAARPAARAGGAAAALDVLRNAGMRVSSDRGGRAGATAKPAAAQPAAEKPAAPR
PAVQVPTPRAAARAPQAAESRQPSPPWEDIPPDDYVPLSADEMFGGSDDGFVPVFDSGPDDVRVTPKPADARPAAPIDTR
PLPPAIALDPIGFDGEWPALAARLPLKGVAYQLAFNSELTAVDAGTLKLSVPVPQYADAAQVTKLKAALADALGKPVEVS
VEVGPARRTAAALDAAARAARQREAEQEIHGDPFVQQLVRDFGARIVEGSVRPLADSAPDGVPPTLH
>Mature_786_residues
TYQVLARKWRPKDFASLVGQEHVVRALTHALDGERLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACRE
IDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQK
IPVTVLSRCLQFNLKQMPAGHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGML
GALDQTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLASLLHRIAWAQFAPGSVLDEWPEAADLRRFAETLSP
EQVQLFYQIATVGRAELGLAPDEYAGFTMTLLRMLAFEPAVGAGSAPGGQPSVPPRAVPAPRAAAAKPVSATPAGAARPQ
AAVPAAPVAPVARSAPAQSSDEAERPAAKPPAAQSPAEAAASVPTAVDAQAIEEPSQPETKAAPAGDVPPPARKEPEPPA
VAAVQRNDEPAPQAEPAPRAASPEPAAARPAARAGGAAAALDVLRNAGMRVSSDRGGRAGATAKPAAAQPAAEKPAAPRP
AVQVPTPRAAARAPQAAESRQPSPPWEDIPPDDYVPLSADEMFGGSDDGFVPVFDSGPDDVRVTPKPADARPAAPIDTRP
LPPAIALDPIGFDGEWPALAARLPLKGVAYQLAFNSELTAVDAGTLKLSVPVPQYADAAQVTKLKAALADALGKPVEVSV
EVGPARRTAAALDAAARAARQREAEQEIHGDPFVQQLVRDFGARIVEGSVRPLADSAPDGVPPTLH

Specific function: The gamma chain seems to interact with the delta subunit to transfer the beta subunit on the DNA [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6677723, Length=327, Percent_Identity=23.5474006116208, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI194306571, Length=325, Percent_Identity=23.0769230769231, Blast_Score=72, Evalue=3e-12,
Organism=Homo sapiens, GI194306567, Length=325, Percent_Identity=23.0769230769231, Blast_Score=72, Evalue=3e-12,
Organism=Escherichia coli, GI1786676, Length=376, Percent_Identity=55.0531914893617, Blast_Score=430, Evalue=1e-121,
Organism=Escherichia coli, GI1787341, Length=183, Percent_Identity=30.6010928961749, Blast_Score=64, Evalue=5e-11,
Organism=Escherichia coli, GI1787119, Length=303, Percent_Identity=27.7227722772277, Blast_Score=63, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71986063, Length=298, Percent_Identity=25.1677852348993, Blast_Score=70, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6324039, Length=245, Percent_Identity=25.7142857142857, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI18859927, Length=295, Percent_Identity=21.3559322033898, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI19921076, Length=305, Percent_Identity=23.2786885245902, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022001
- InterPro:   IPR022754
- InterPro:   IPR012763
- InterPro:   IPR021029 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3; PF12168 DNA_pol3_tau_4; PF12170 DNA_pol3_tau_5 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 82646; Mature: 82515

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGERLHHAYLFTGTRGVGKTTLSRIFAK
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEEECCCCCCHHHHHHHHHH
ALNCETGVTSQPCGVCRACREIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARF
HHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCE
KVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSRCLQFNLKQMPA
EEEEECHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCH
GHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGM
HHHHHHHHHHHCCCCEEECHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGALDQTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLASLLHRIAWAQFAPG
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SVLDEWPEAADLRRFAETLSPEQVQLFYQIATVGRAELGLAPDEYAGFTMTLLRMLAFEP
HHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHCHHHCCCCCHHHCHHHHHHHHHHHHCC
AVGAGSAPGGQPSVPPRAVPAPRAAAAKPVSATPAGAARPQAAVPAAPVAPVARSAPAQS
CCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCC
SDEAERPAAKPPAAQSPAEAAASVPTAVDAQAIEEPSQPETKAAPAGDVPPPARKEPEPP
CCHHHCCCCCCCCCCCHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
AVAAVQRNDEPAPQAEPAPRAASPEPAAARPAARAGGAAAALDVLRNAGMRVSSDRGGRA
CEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHCCCEEECCCCCCC
GATAKPAAAQPAAEKPAAPRPAVQVPTPRAAARAPQAAESRQPSPPWEDIPPDDYVPLSA
CCCCCCCCCCCCCCCCCCCCCCEECCCCHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCH
DEMFGGSDDGFVPVFDSGPDDVRVTPKPADARPAAPIDTRPLPPAIALDPIGFDGEWPAL
HHHCCCCCCCEEEEECCCCCCCEECCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCHH
AARLPLKGVAYQLAFNSELTAVDAGTLKLSVPVPQYADAAQVTKLKAALADALGKPVEVS
HHHCCCCCEEEEEEECCCEEEEECCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEE
VEVGPARRTAAALDAAARAARQREAEQEIHGDPFVQQLVRDFGARIVEGSVRPLADSAPD
EEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
GVPPTLH
CCCCCCC
>Mature Secondary Structure 
TYQVLARKWRPKDFASLVGQEHVVRALTHALDGERLHHAYLFTGTRGVGKTTLSRIFAK
CHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEEECCCCCCHHHHHHHHHH
ALNCETGVTSQPCGVCRACREIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARF
HHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCE
KVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSRCLQFNLKQMPA
EEEEECHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCH
GHIVSHLERILGEEQITFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTESAVSGM
HHHHHHHHHHHCCCCEEECHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGALDQTYMVRLLDALAAANGPEILAIADEMSLRSLSFSTALQDLASLLHRIAWAQFAPG
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SVLDEWPEAADLRRFAETLSPEQVQLFYQIATVGRAELGLAPDEYAGFTMTLLRMLAFEP
HHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHCHHHCCCCCHHHCHHHHHHHHHHHHCC
AVGAGSAPGGQPSVPPRAVPAPRAAAAKPVSATPAGAARPQAAVPAAPVAPVARSAPAQS
CCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCC
SDEAERPAAKPPAAQSPAEAAASVPTAVDAQAIEEPSQPETKAAPAGDVPPPARKEPEPP
CCHHHCCCCCCCCCCCHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
AVAAVQRNDEPAPQAEPAPRAASPEPAAARPAARAGGAAAALDVLRNAGMRVSSDRGGRA
CEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHCCCEEECCCCCCC
GATAKPAAAQPAAEKPAAPRPAVQVPTPRAAARAPQAAESRQPSPPWEDIPPDDYVPLSA
CCCCCCCCCCCCCCCCCCCCCCEECCCCHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCH
DEMFGGSDDGFVPVFDSGPDDVRVTPKPADARPAAPIDTRPLPPAIALDPIGFDGEWPAL
HHHCCCCCCCEEEEECCCCCCCEECCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCHH
AARLPLKGVAYQLAFNSELTAVDAGTLKLSVPVPQYADAAQVTKLKAALADALGKPVEVS
HHHCCCCCEEEEEEECCCEEEEECCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEE
VEVGPARRTAAALDAAARAARQREAEQEIHGDPFVQQLVRDFGARIVEGSVRPLADSAPD
EEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
GVPPTLH
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3534795; 3018672; 9278503; 2186364; 2187190; 2181440; 1575709 [H]