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The map label for this gene is mdcB [H]

Identifier: 116689296

GI number: 116689296

Start: 1404349

End: 1405215

Strand: Direct

Name: mdcB [H]

Synonym: Bcen2424_1274

Alternate gene names: 116689296

Gene position: 1404349-1405215 (Clockwise)

Preceding gene: 116689295

Following gene: 116689297

Centisome position: 40.31

GC content: 74.74

Gene sequence:

>867_bases
ATGAACGCACGGGCTGCCTGCCGCGTAGCGGCGCCGTCCGACGCCGAACGCATCGCCGCGCTGGCCGAGCGCAGCCTCGT
GCTCGAGATCGACACCTATCCGAAGCCGGGCCTCGTCAGTCACGTCGACACCGGCAGTCACACGGACATGGATGCCGCGA
CGTTCGCGCGCAGCGCCGCCGTGCTGCGGCCGTACTTCGCGGAACTCGCCGACGCGGGCGCCCGCGACGCGGACATGGCC
GTGCTGCGCAAGATCGGCCTGCGTGCCGAGCACGCGATGCTCGCCGCGACCGGCGGCGTCAATACGCATCGCGGCGCGAT
CTTCGGGCTCGGGCTGCTGTGCGCGGCTGCCGGCCGGCGCGCACTGTCGGGCGCGGTGCTGGACGGGACGACGCTCGGCG
CGTTCGTATCCCGTCGCTGGGGCGTCGAGATCCTCGGCGGCCCGCGTTTGCCGGACAGCCACGGCGAGTGCGCGAGCCGC
CGCTACGGTGTGGGCGGTGCGCGTCGCGAGGCGGCCGACGGCTTTCCGACCGTGTACGCGGTCGGGTTGCCCGCGCTGCG
CGGCGCCCAGCGCGACTTGCCGGACGATCCGGAAGCCGCGCGGGTCGCCGCGTGCTTCGCGCTGATCGCCGCGCTCGACG
ACACGAATCTGCTGCACCGGGGCGGGCAGGACGGCCTCGATTTCGCTCGCGCGACCGCTCGTGCCTTCGTCGCGCGCGGC
GGCGTGCGGGCGCCCGACTGGCGGCTGCGCGCGGCGGCCGCGCATCGGGCGTTCGTCGCACGCCGGCTGAGCCCGGGCGG
GGCGGCCGACCTGCTCGCGATGAGCGTGTTCGTCGATGCGCTCGAAGCCGAAGGGCACGCACGATGA

Upstream 100 bases:

>100_bases
TCAACTGGCGCGAACTGCACGCGCGCTTGCCCGAAGTCGCGGTGAAGACCGCGATTGCGGTCGAATTGATACGCGCCGAT
GCCTTCACCGGAGGCCTGCG

Downstream 100 bases:

>100_bases
CGCTGGCCATCCTGTGTTCGGGGCAAGGCGCGCAACGCGCCGACATGTTCGATCTGACCGGGTCGGCGCCGCAGGCCGAC
GCATTGTTCGCGCATGCGGG

Product: triphosphoribosyl-dephospho-CoA synthase

Products: NA

Alternate protein names: 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MNARAACRVAAPSDAERIAALAERSLVLEIDTYPKPGLVSHVDTGSHTDMDAATFARSAAVLRPYFAELADAGARDADMA
VLRKIGLRAEHAMLAATGGVNTHRGAIFGLGLLCAAAGRRALSGAVLDGTTLGAFVSRRWGVEILGGPRLPDSHGECASR
RYGVGGARREAADGFPTVYAVGLPALRGAQRDLPDDPEAARVAACFALIAALDDTNLLHRGGQDGLDFARATARAFVARG
GVRAPDWRLRAAAAHRAFVARRLSPGGAADLLAMSVFVDALEAEGHAR

Sequences:

>Translated_288_residues
MNARAACRVAAPSDAERIAALAERSLVLEIDTYPKPGLVSHVDTGSHTDMDAATFARSAAVLRPYFAELADAGARDADMA
VLRKIGLRAEHAMLAATGGVNTHRGAIFGLGLLCAAAGRRALSGAVLDGTTLGAFVSRRWGVEILGGPRLPDSHGECASR
RYGVGGARREAADGFPTVYAVGLPALRGAQRDLPDDPEAARVAACFALIAALDDTNLLHRGGQDGLDFARATARAFVARG
GVRAPDWRLRAAAAHRAFVARRLSPGGAADLLAMSVFVDALEAEGHAR
>Mature_288_residues
MNARAACRVAAPSDAERIAALAERSLVLEIDTYPKPGLVSHVDTGSHTDMDAATFARSAAVLRPYFAELADAGARDADMA
VLRKIGLRAEHAMLAATGGVNTHRGAIFGLGLLCAAAGRRALSGAVLDGTTLGAFVSRRWGVEILGGPRLPDSHGECASR
RYGVGGARREAADGFPTVYAVGLPALRGAQRDLPDDPEAARVAACFALIAALDDTNLLHRGGQDGLDFARATARAFVARG
GVRAPDWRLRAAAAHRAFVARRLSPGGAADLLAMSVFVDALEAEGHAR

Specific function: Involved in the formation of 2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase [H]

COG id: COG1767

COG function: function code H; Triphosphoribosyl-dephospho-CoA synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitG/MdcB family [H]

Homologues:

Organism=Escherichia coli, GI1786830, Length=285, Percent_Identity=34.7368421052632, Blast_Score=136, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002736
- InterPro:   IPR017555 [H]

Pfam domain/function: PF01874 CitG [H]

EC number: =2.7.8.25 [H]

Molecular weight: Translated: 29966; Mature: 29966

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNARAACRVAAPSDAERIAALAERSLVLEIDTYPKPGLVSHVDTGSHTDMDAATFARSAA
CCCCCEEEECCCCCHHHHHHHHHCCEEEEEECCCCCCCCEECCCCCCCCCHHHHHHHHHH
VLRPYFAELADAGARDADMAVLRKIGLRAEHAMLAATGGVNTHRGAIFGLGLLCAAAGRR
HHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHH
ALSGAVLDGTTLGAFVSRRWGVEILGGPRLPDSHGECASRRYGVGGARREAADGFPTVYA
HHCCCEECCHHHHHHHHHHCCEEEECCCCCCCCCCCHHHHHCCCCCCHHHHCCCCCEEEE
VGLPALRGAQRDLPDDPEAARVAACFALIAALDDTNLLHRGGQDGLDFARATARAFVARG
CCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHCC
GVRAPDWRLRAAAAHRAFVARRLSPGGAADLLAMSVFVDALEAEGHAR
CCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNARAACRVAAPSDAERIAALAERSLVLEIDTYPKPGLVSHVDTGSHTDMDAATFARSAA
CCCCCEEEECCCCCHHHHHHHHHCCEEEEEECCCCCCCCEECCCCCCCCCHHHHHHHHHH
VLRPYFAELADAGARDADMAVLRKIGLRAEHAMLAATGGVNTHRGAIFGLGLLCAAAGRR
HHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHH
ALSGAVLDGTTLGAFVSRRWGVEILGGPRLPDSHGECASRRYGVGGARREAADGFPTVYA
HHCCCEECCHHHHHHHHHHCCEEEECCCCCCCCCCCHHHHHCCCCCCHHHHCCCCCEEEE
VGLPALRGAQRDLPDDPEAARVAACFALIAALDDTNLLHRGGQDGLDFARATARAFVARG
CCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHCC
GVRAPDWRLRAAAAHRAFVARRLSPGGAADLLAMSVFVDALEAEGHAR
CCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10561613 [H]