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The map label for this gene is yjcC [H]

Identifier: 116689240

GI number: 116689240

Start: 1348705

End: 1349985

Strand: Reverse

Name: yjcC [H]

Synonym: Bcen2424_1218

Alternate gene names: 116689240

Gene position: 1349985-1348705 (Counterclockwise)

Preceding gene: 116689241

Following gene: 116689235

Centisome position: 38.75

GC content: 69.95

Gene sequence:

>1281_bases
ATGAAGTCCACCCGCGACCTGTCGCTCGACGCCCTGCTCGAACGCCTCACGCCGACGCCTCAGGGCTGGCTCGCCACCTA
TCGCACCACGACCTTGCGCAGCGTGTTCCAGCCCGTGCTGTCGATCACGCACAAGCGTGTCGTCGGCTACGAGGCACTGC
TGCGCGTCGTCGACGGCAACGGCGCGCTGGCGTCGCCTACCGCCCTGTTCGACAAGGCGCGCGGCGACGCCGACGCGCTG
CTGCTCGACCGGCTCGCGCGCTGCCTGCACACGGCCAACTTCGTCGCGCAGGGGATCGGCGACGGCTGGCTGTTCCTGAA
CGTGACGCCGCGCGTGCTGGACACGGGCCTCGTGCAGCGCGAGTTCGTCGAGGCGCTGTGCCGGCATTTCGCACTGCCGC
CGAATCGCATCGTGCTGGAGGTGATCGAGCAGCCGGCGCGCGACGAAGCCGCGCTCGCCCGCACGATCGACATGATCCAG
CATCGCGATTTCCTGATCGCGATCGACGATTTCGGCACCGGCTTCTCGAACTTCGACCGCGTGTGGCGGGCACGGCCCGA
CATCGTGAAGCTCGACCGTTCGCTCGTCGAGCGATCGACCGGCTCGGCCGAGGATCGCCGCATCATGCATCACCTCGTGT
CGATGCTGCACCAGGCCGGCGCGATGGTGCTGGCCGAAGGCGTCGAAAGCGACGACGCGCTGCAGGCGCTGATGGAAGCC
GACATCGATTTCGTGCAGGGTTTCCAGTTCGGCCAGCCCGATGCATCGATCGCGCACGCGAGCGCCGCGGCACCCGCGAT
GCTCGATGCCGCGTGGCGGCGCTTCCTCGCCCGCCGGCACACGCCGGTGGCCCCCGAGCAGCCCGGCTTCGACGCGATCG
AACGGCTCGTGCTCGGCGGCGCGGCCGCGTTTTCAGCGAGCGGCAACCTGCAGGACGCCGCGCAACGCGTGTTCGCGGTG
CCGGCCGCGCGTCGCGTGTTCGTCACGGACGAGACCGGCGAACAGTTCCTGCCGTCGATCGGCGCACCGCCCGACGACAG
CCAGGCGAGCGTGACGCGTCTCGCGCCGCTGTTCCCGGAAACCCACAGCAACTGGTCGCGACGCCCGTATTTCCAGCGCG
CGATCGCCGCCCCCGGGCGCGTCGCGCTGATGGGGCCGCACTTCTCGCTGACGGAAGGCCGCGACTGCTATACGGCCGCC
GTCGCGATCCGCGCGCAGAGCCGGCTCGTCGTGTTCTGCGTCGACTTCGTGCTCGACAGCGCCGGAACCGTGATGCGGTA
G

Upstream 100 bases:

>100_bases
GTCTCGATGCTCCACGTTCTTTTGCGTCCGCCTGCGCATGCGGCTGCATCGGCGTGGCGATGCGCCGCCGCCCCGCCGCC
CGCTGCCGGGCACCGTTGAC

Downstream 100 bases:

>100_bases
CCGGCGCGCACGGCGCACGTTCGCCTGCGACCCGCACCGGCCCTTCGCTCGTCAGTCGATCACCTTCCCTCGTCCTGACT
TCACCGTGCTGCGGCGCGAC

Product: diguanylate phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MKSTRDLSLDALLERLTPTPQGWLATYRTTTLRSVFQPVLSITHKRVVGYEALLRVVDGNGALASPTALFDKARGDADAL
LLDRLARCLHTANFVAQGIGDGWLFLNVTPRVLDTGLVQREFVEALCRHFALPPNRIVLEVIEQPARDEAALARTIDMIQ
HRDFLIAIDDFGTGFSNFDRVWRARPDIVKLDRSLVERSTGSAEDRRIMHHLVSMLHQAGAMVLAEGVESDDALQALMEA
DIDFVQGFQFGQPDASIAHASAAAPAMLDAAWRRFLARRHTPVAPEQPGFDAIERLVLGGAAAFSASGNLQDAAQRVFAV
PAARRVFVTDETGEQFLPSIGAPPDDSQASVTRLAPLFPETHSNWSRRPYFQRAIAAPGRVALMGPHFSLTEGRDCYTAA
VAIRAQSRLVVFCVDFVLDSAGTVMR

Sequences:

>Translated_426_residues
MKSTRDLSLDALLERLTPTPQGWLATYRTTTLRSVFQPVLSITHKRVVGYEALLRVVDGNGALASPTALFDKARGDADAL
LLDRLARCLHTANFVAQGIGDGWLFLNVTPRVLDTGLVQREFVEALCRHFALPPNRIVLEVIEQPARDEAALARTIDMIQ
HRDFLIAIDDFGTGFSNFDRVWRARPDIVKLDRSLVERSTGSAEDRRIMHHLVSMLHQAGAMVLAEGVESDDALQALMEA
DIDFVQGFQFGQPDASIAHASAAAPAMLDAAWRRFLARRHTPVAPEQPGFDAIERLVLGGAAAFSASGNLQDAAQRVFAV
PAARRVFVTDETGEQFLPSIGAPPDDSQASVTRLAPLFPETHSNWSRRPYFQRAIAAPGRVALMGPHFSLTEGRDCYTAA
VAIRAQSRLVVFCVDFVLDSAGTVMR
>Mature_426_residues
MKSTRDLSLDALLERLTPTPQGWLATYRTTTLRSVFQPVLSITHKRVVGYEALLRVVDGNGALASPTALFDKARGDADAL
LLDRLARCLHTANFVAQGIGDGWLFLNVTPRVLDTGLVQREFVEALCRHFALPPNRIVLEVIEQPARDEAALARTIDMIQ
HRDFLIAIDDFGTGFSNFDRVWRARPDIVKLDRSLVERSTGSAEDRRIMHHLVSMLHQAGAMVLAEGVESDDALQALMEA
DIDFVQGFQFGQPDASIAHASAAAPAMLDAAWRRFLARRHTPVAPEQPGFDAIERLVLGGAAAFSASGNLQDAAQRVFAV
PAARRVFVTDETGEQFLPSIGAPPDDSQASVTRLAPLFPETHSNWSRRPYFQRAIAAPGRVALMGPHFSLTEGRDCYTAA
VAIRAQSRLVVFCVDFVLDSAGTVMR

Specific function: Overexpression reduces biofilm formation [H]

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1790496, Length=223, Percent_Identity=26.457399103139, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI87081845, Length=232, Percent_Identity=27.1551724137931, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1788849, Length=225, Percent_Identity=26.2222222222222, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081743, Length=226, Percent_Identity=25.6637168141593, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082096, Length=130, Percent_Identity=29.2307692307692, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787055, Length=225, Percent_Identity=26.2222222222222, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI87081980, Length=251, Percent_Identity=24.7011952191235, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1786507, Length=120, Percent_Identity=29.1666666666667, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 46692; Mature: 46692

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSTRDLSLDALLERLTPTPQGWLATYRTTTLRSVFQPVLSITHKRVVGYEALLRVVDGN
CCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GALASPTALFDKARGDADALLLDRLARCLHTANFVAQGIGDGWLFLNVTPRVLDTGLVQR
CCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHH
EFVEALCRHFALPPNRIVLEVIEQPARDEAALARTIDMIQHRDFLIAIDDFGTGFSNFDR
HHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHH
VWRARPDIVKLDRSLVERSTGSAEDRRIMHHLVSMLHQAGAMVLAEGVESDDALQALMEA
HHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHEECCCCCCHHHHHHHHHH
DIDFVQGFQFGQPDASIAHASAAAPAMLDAAWRRFLARRHTPVAPEQPGFDAIERLVLGG
CHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCC
AAAFSASGNLQDAAQRVFAVPAARRVFVTDETGEQFLPSIGAPPDDSQASVTRLAPLFPE
HHHHCCCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHCCCCCCCCCCCHHHHHHHHCCCC
THSNWSRRPYFQRAIAAPGRVALMGPHFSLTEGRDCYTAAVAIRAQSRLVVFCVDFVLDS
CCCCCCCCHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHC
AGTVMR
CCCCCC
>Mature Secondary Structure
MKSTRDLSLDALLERLTPTPQGWLATYRTTTLRSVFQPVLSITHKRVVGYEALLRVVDGN
CCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GALASPTALFDKARGDADALLLDRLARCLHTANFVAQGIGDGWLFLNVTPRVLDTGLVQR
CCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHH
EFVEALCRHFALPPNRIVLEVIEQPARDEAALARTIDMIQHRDFLIAIDDFGTGFSNFDR
HHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHH
VWRARPDIVKLDRSLVERSTGSAEDRRIMHHLVSMLHQAGAMVLAEGVESDDALQALMEA
HHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHEECCCCCCHHHHHHHHHH
DIDFVQGFQFGQPDASIAHASAAAPAMLDAAWRRFLARRHTPVAPEQPGFDAIERLVLGG
CHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCC
AAAFSASGNLQDAAQRVFAVPAARRVFVTDETGEQFLPSIGAPPDDSQASVTRLAPLFPE
HHHHCCCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHCCCCCCCCCCCHHHHHHHHCCCC
THSNWSRRPYFQRAIAAPGRVALMGPHFSLTEGRDCYTAAVAIRAQSRLVVFCVDFVLDS
CCCCCCCCHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHC
AGTVMR
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]