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The map label for this gene is fabD [H]

Identifier: 116689144

GI number: 116689144

Start: 1233390

End: 1234322

Strand: Direct

Name: fabD [H]

Synonym: Bcen2424_1122

Alternate gene names: 116689144

Gene position: 1233390-1234322 (Clockwise)

Preceding gene: 116689143

Following gene: 116689145

Centisome position: 35.4

GC content: 68.6

Gene sequence:

>933_bases
ATGAAATTTGCATTCGTTTTTCCGGGGCAGGGTTCGCAGGCGATCGGGATGCTCGACGCATTCGCCGATCTGGCCGTCGT
GCGCGAGACGCTCCAGGAAGCATCCGATGCACTCAATCAGGATCTCGGCAAGCTGATCGCCGAAGGCCCGGCCGAAGAGC
TGAACCTGACCACCAACACGCAGCCCGTGATGCTGACCGCGGCGTACGCGTGCTATCGCGCGTGGCAGCAGGCAGGCGGC
CCGGCGCCGTCGATCGTCGCCGGCCACAGCCTCGGTGAATACACGGCGCTCGTCGCGGCCGGCGCGCTCGCGTTCAAGGA
CGCGGTGCCGCTCGTGCGCTTCCGCGCGCAGGCCATGCAGACGGCCGTGCCGGTGGGCCAGGGCGGCATGGCCGCGATCC
TGGGCCTCGACGACGACACGGTACGCGCGGTATGCGCCGAAGCCGCGGAAGCGGGCGTCGTCGAAGCGGTGAACTTCAAT
GCGCCCGCGCAGGTCGTGATCGCAGGCAGCAAGGCCGCGGTCGAAAAGGCATGCGAAATCGCGAAGGCGAAGGGCGCGAA
GCGCGCGCTGCCGCTGCCGGTGTCGGCGCCGTTCCATTCGTCGCTGCTCAAGCCGGCGTCGGATCAGTTGCGCGACTATC
TCGCGAACGTCGACGTGAAGGCGCCGCAGATTCCGGTCGTCAACAACATCGACGTCGCCGTGGTCAGCGATCCGGCCGCG
ATCAAGGATGCGCTGGTGCGCCAGGCCGCGGGCCCGGTGCGCTGGGTCGAGTGCGTGCGGCACATCGCCGGCACGGGCGT
CACGCACGTGATCGAATGCGGTCCGGGCAAGGTGCTCGCCGGCCTGACGAAGCGCATCGACGGCAACCTGGTCGGCGCCT
CGGTGTTCGATCCGGCTTCGCTCGACGAAGCGCTCAAGCTCGCGACCGCCTGA

Upstream 100 bases:

>100_bases
TCGGTCTTCCGCTTCTGATCCGCGGCGCGCATTGCCGCGCGCGGGTCCCATCGGCGCGCCGTTCGTGCGCGCCGTCCGAA
TCGATTCAATTGGGGACGAT

Downstream 100 bases:

>100_bases
CGCGGCGCCTTTTCCCAAGCAACGGATATTCGATTCATGGACAAGACTCTCGATAAACAGGTTGCGATCGTGACCGGCGC
GTCGCGCGGCATCGGCCGTT

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MKFAFVFPGQGSQAIGMLDAFADLAVVRETLQEASDALNQDLGKLIAEGPAEELNLTTNTQPVMLTAAYACYRAWQQAGG
PAPSIVAGHSLGEYTALVAAGALAFKDAVPLVRFRAQAMQTAVPVGQGGMAAILGLDDDTVRAVCAEAAEAGVVEAVNFN
APAQVVIAGSKAAVEKACEIAKAKGAKRALPLPVSAPFHSSLLKPASDQLRDYLANVDVKAPQIPVVNNIDVAVVSDPAA
IKDALVRQAAGPVRWVECVRHIAGTGVTHVIECGPGKVLAGLTKRIDGNLVGASVFDPASLDEALKLATA

Sequences:

>Translated_310_residues
MKFAFVFPGQGSQAIGMLDAFADLAVVRETLQEASDALNQDLGKLIAEGPAEELNLTTNTQPVMLTAAYACYRAWQQAGG
PAPSIVAGHSLGEYTALVAAGALAFKDAVPLVRFRAQAMQTAVPVGQGGMAAILGLDDDTVRAVCAEAAEAGVVEAVNFN
APAQVVIAGSKAAVEKACEIAKAKGAKRALPLPVSAPFHSSLLKPASDQLRDYLANVDVKAPQIPVVNNIDVAVVSDPAA
IKDALVRQAAGPVRWVECVRHIAGTGVTHVIECGPGKVLAGLTKRIDGNLVGASVFDPASLDEALKLATA
>Mature_310_residues
MKFAFVFPGQGSQAIGMLDAFADLAVVRETLQEASDALNQDLGKLIAEGPAEELNLTTNTQPVMLTAAYACYRAWQQAGG
PAPSIVAGHSLGEYTALVAAGALAFKDAVPLVRFRAQAMQTAVPVGQGGMAAILGLDDDTVRAVCAEAAEAGVVEAVNFN
APAQVVIAGSKAAVEKACEIAKAKGAKRALPLPVSAPFHSSLLKPASDQLRDYLANVDVKAPQIPVVNNIDVAVVSDPAA
IKDALVRQAAGPVRWVECVRHIAGTGVTHVIECGPGKVLAGLTKRIDGNLVGASVFDPASLDEALKLATA

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=301, Percent_Identity=32.5581395348837, Blast_Score=146, Evalue=3e-35,
Organism=Escherichia coli, GI1787334, Length=307, Percent_Identity=57.0032573289902, Blast_Score=323, Evalue=1e-89,
Organism=Caenorhabditis elegans, GI71984332, Length=265, Percent_Identity=32.0754716981132, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17550940, Length=294, Percent_Identity=29.5918367346939, Blast_Score=110, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24665753, Length=308, Percent_Identity=31.4935064935065, Blast_Score=131, Evalue=6e-31,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 31879; Mature: 31879

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFAFVFPGQGSQAIGMLDAFADLAVVRETLQEASDALNQDLGKLIAEGPAEELNLTTNT
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCEECCCC
QPVMLTAAYACYRAWQQAGGPAPSIVAGHSLGEYTALVAAGALAFKDAVPLVRFRAQAMQ
CCHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAVPVGQGGMAAILGLDDDTVRAVCAEAAEAGVVEAVNFNAPAQVVIAGSKAAVEKACEI
HHCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCEEEECCCCCEEEEEECCHHHHHHHHHH
AKAKGAKRALPLPVSAPFHSSLLKPASDQLRDYLANVDVKAPQIPVVNNIDVAVVSDPAA
HHHCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCHH
IKDALVRQAAGPVRWVECVRHIAGTGVTHVIECGPGKVLAGLTKRIDGNLVGASVFDPAS
HHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCEECCCCCCCHH
LDEALKLATA
HHHHHHHHCC
>Mature Secondary Structure
MKFAFVFPGQGSQAIGMLDAFADLAVVRETLQEASDALNQDLGKLIAEGPAEELNLTTNT
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCEECCCC
QPVMLTAAYACYRAWQQAGGPAPSIVAGHSLGEYTALVAAGALAFKDAVPLVRFRAQAMQ
CCHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAVPVGQGGMAAILGLDDDTVRAVCAEAAEAGVVEAVNFNAPAQVVIAGSKAAVEKACEI
HHCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCEEEECCCCCEEEEEECCHHHHHHHHHH
AKAKGAKRALPLPVSAPFHSSLLKPASDQLRDYLANVDVKAPQIPVVNNIDVAVVSDPAA
HHHCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCHH
IKDALVRQAAGPVRWVECVRHIAGTGVTHVIECGPGKVLAGLTKRIDGNLVGASVFDPAS
HHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCEECCCCCCCHH
LDEALKLATA
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]