Click here to switch to the map view.

The map label for this gene is yhfN [H]

Identifier: 116689100

GI number: 116689100

Start: 1189137

End: 1190396

Strand: Reverse

Name: yhfN [H]

Synonym: Bcen2424_1077

Alternate gene names: 116689100

Gene position: 1190396-1189137 (Counterclockwise)

Preceding gene: 116689102

Following gene: 116689099

Centisome position: 34.17

GC content: 66.35

Gene sequence:

>1260_bases
ATGTCACCCTTTTCGTTCACCCTGCTGTTCGCGATCGCCGTACTCGCGATGGTCGTCACCAAGCTGTGGCTCGCGTCGCG
GCAGATCCGCTTCGTCGCCGCGCACCGCAACGGCGTGCCCGCGCAATTCAGCGCCACCATCCCGCTGACCGCCCACCAGC
GCGCGGCCGACTACACGGTCGAGCGCACCCGGCTGACGATGCTCGAGATCGTCGTCAGCGCGGCCGTGCTGGTCGGCCTC
ACGCTGCTCGGCGGCGTCGGCGCGCTCGACACACTGCTGACCGGCTGGCTTGGCCGCGGCTACGGGCAGCAGGTCGCGCT
GGTCGCCGCGGTGCTCGTGATCACGGGCGTGATCGACGTGCCGTTCGAGTATTACCGCCAGTTCGGCATCGAGCAGCGTT
TCGGCTTCAACCGGATGACGAAGCGGCTGTTCTTCACCGACATGCTGAAGAATTCGCTGCTCGGCGCCGTGCTCGGCCTG
CCGCTGCTGTTCGTCGTGCTGTGGCTGATGAACCAGGCCGGCAGCCTGTGGTGGCTGTGGACCTGGATCGTGTGGGTCGC
GTTCCAGATGCTCGTGCTGCTGATCTACCCGACCTTCATCGCGCCGCTTTTCAACAAGTTCGAGCCGCTGAAGGACGACG
CGCTGCGCGCGCGCATCGAGTCGCTGATGAAGCGCTGCGGTTTCGCGGCGAAGGGGCTGTTCGTAATGGACGGCAGCCGC
CGCTCCGCGCACGGCAACGCGTATTTCACGGGCTTCGGCGCCTCGAAGCGGATCGTGTTCTTCGACACGCTGCTCGCGCG
CCTGTCCGGCCAGGAAATCGAAGCCGTACTCGCGCACGAACTCGGCCACTTCAAGCGCCGCCACGTGATGAAGCGGATGC
TCGTGTCGTTCGTGCTGAGCCTCGTGCTGCTCGCGCTGCTCGGCTGGCTCGCGCAACGCACGTGGTTCTACACGGGGCTC
GGCGTCACGCCGTCGCTCGACACCAGCAACGCGGGCGCGGCGCTCATCCTGTTCTTCCTCGCGATTCCGGTATTCCTGTT
CTTCGCGACGCCGTTCAGCAGCCTCACGTCGCGCAAGCACGAATTCGAGGCCGACGCGTTCGCGGCCAGCCAGACCGACG
CGCAGGATCTCGTCAGCGCGCTCGTGAAACTCTACGAGGACAACGCGTCGACGCTGACGCCCGACCCCGTCTACACGGCT
TTCTACTACTCGCATCCGCCCGCCTCGCAGCGGATCGACCGCCTGCTGCAGCACGCATGA

Upstream 100 bases:

>100_bases
GGCCTCGCCGATGCAGCGCCGCCCGGGCGGCCGGCATCGCATCAGCGGGGCCGGTCCGCAAGAACATATAATTCTCGCAT
AGAACCCTTTGGCGCCTTCG

Downstream 100 bases:

>100_bases
GCCGGCCGACTTCCCGCAAGCCGGCCCCGCGCGCATCGGGCGCGCAACGGGCCGAAGGCCGCGTGATCGCGGCGCACGGC
CGCCACTACATCGTCGCCCC

Product: Ste24 endopeptidase

Products: NA

Alternate protein names: PSP23 [H]

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MSPFSFTLLFAIAVLAMVVTKLWLASRQIRFVAAHRNGVPAQFSATIPLTAHQRAADYTVERTRLTMLEIVVSAAVLVGL
TLLGGVGALDTLLTGWLGRGYGQQVALVAAVLVITGVIDVPFEYYRQFGIEQRFGFNRMTKRLFFTDMLKNSLLGAVLGL
PLLFVVLWLMNQAGSLWWLWTWIVWVAFQMLVLLIYPTFIAPLFNKFEPLKDDALRARIESLMKRCGFAAKGLFVMDGSR
RSAHGNAYFTGFGASKRIVFFDTLLARLSGQEIEAVLAHELGHFKRRHVMKRMLVSFVLSLVLLALLGWLAQRTWFYTGL
GVTPSLDTSNAGAALILFFLAIPVFLFFATPFSSLTSRKHEFEADAFAASQTDAQDLVSALVKLYEDNASTLTPDPVYTA
FYYSHPPASQRIDRLLQHA

Sequences:

>Translated_419_residues
MSPFSFTLLFAIAVLAMVVTKLWLASRQIRFVAAHRNGVPAQFSATIPLTAHQRAADYTVERTRLTMLEIVVSAAVLVGL
TLLGGVGALDTLLTGWLGRGYGQQVALVAAVLVITGVIDVPFEYYRQFGIEQRFGFNRMTKRLFFTDMLKNSLLGAVLGL
PLLFVVLWLMNQAGSLWWLWTWIVWVAFQMLVLLIYPTFIAPLFNKFEPLKDDALRARIESLMKRCGFAAKGLFVMDGSR
RSAHGNAYFTGFGASKRIVFFDTLLARLSGQEIEAVLAHELGHFKRRHVMKRMLVSFVLSLVLLALLGWLAQRTWFYTGL
GVTPSLDTSNAGAALILFFLAIPVFLFFATPFSSLTSRKHEFEADAFAASQTDAQDLVSALVKLYEDNASTLTPDPVYTA
FYYSHPPASQRIDRLLQHA
>Mature_418_residues
SPFSFTLLFAIAVLAMVVTKLWLASRQIRFVAAHRNGVPAQFSATIPLTAHQRAADYTVERTRLTMLEIVVSAAVLVGLT
LLGGVGALDTLLTGWLGRGYGQQVALVAAVLVITGVIDVPFEYYRQFGIEQRFGFNRMTKRLFFTDMLKNSLLGAVLGLP
LLFVVLWLMNQAGSLWWLWTWIVWVAFQMLVLLIYPTFIAPLFNKFEPLKDDALRARIESLMKRCGFAAKGLFVMDGSRR
SAHGNAYFTGFGASKRIVFFDTLLARLSGQEIEAVLAHELGHFKRRHVMKRMLVSFVLSLVLLALLGWLAQRTWFYTGLG
VTPSLDTSNAGAALILFFLAIPVFLFFATPFSSLTSRKHEFEADAFAASQTDAQDLVSALVKLYEDNASTLTPDPVYTAF
YYSHPPASQRIDRLLQHA

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Homo sapiens, GI18379366, Length=443, Percent_Identity=28.2167042889391, Blast_Score=182, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI17505484, Length=421, Percent_Identity=29.6912114014252, Blast_Score=190, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6322577, Length=309, Percent_Identity=39.1585760517799, Blast_Score=216, Evalue=5e-57,
Organism=Drosophila melanogaster, GI19922414, Length=442, Percent_Identity=30.9954751131222, Blast_Score=199, Evalue=3e-51,
Organism=Drosophila melanogaster, GI78707252, Length=411, Percent_Identity=25.3041362530414, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI78707254, Length=411, Percent_Identity=25.3041362530414, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24654305, Length=438, Percent_Identity=26.9406392694064, Blast_Score=120, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 46764; Mature: 46633

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SPFSFTLLFAIAVLAMVVTKLWLASRQIRFVAAHRNGVPAQFSATIPLTAHQRAADYTV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEECCCCHHHHHHHHHH
ERTRLTMLEIVVSAAVLVGLTLLGGVGALDTLLTGWLGRGYGQQVALVAAVLVITGVIDV
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHC
PFEYYRQFGIEQRFGFNRMTKRLFFTDMLKNSLLGAVLGLPLLFVVLWLMNQAGSLWWLW
CHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
TWIVWVAFQMLVLLIYPTFIAPLFNKFEPLKDDALRARIESLMKRCGFAAKGLFVMDGSR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHCCEEEECCCC
RSAHGNAYFTGFGASKRIVFFDTLLARLSGQEIEAVLAHELGHFKRRHVMKRMLVSFVLS
CCCCCCEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVLLALLGWLAQRTWFYTGLGVTPSLDTSNAGAALILFFLAIPVFLFFATPFSSLTSRKH
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
EFEADAFAASQTDAQDLVSALVKLYEDNASTLTPDPVYTAFYYSHPPASQRIDRLLQHA
HCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 3145906 [H]