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The map label for this gene is udg [H]

Identifier: 116689074

GI number: 116689074

Start: 1165247

End: 1166647

Strand: Direct

Name: udg [H]

Synonym: Bcen2424_1051

Alternate gene names: 116689074

Gene position: 1165247-1166647 (Clockwise)

Preceding gene: 116689073

Following gene: 116689075

Centisome position: 33.45

GC content: 66.88

Gene sequence:

>1401_bases
ATGAAAATCACCATCATCGGCACCGGCTATGTCGGCCTCGTCACGGGCGCCTGCCTCGCGGAGATCGGTCACGACGTCTT
CTGTCTCGATGTCGATCCGCGCAAGATCGACATCCTGAACAACGGCGGGATGCCGATTCACGAACCGGGGCTGCTGGACA
TCATCGCGCGCAACCGCACGGCGGGGCGCCTGCGTTTCTCGACCGACATCGAGGCGAGCGTCGCGCATGGCGAGATCCAG
TTCATCGCCGTCGGCACGCCGCCTGACGAGGACGGCTCGGCCGACCTGCAATACGTGCTCGAGGCCGCGCGCAACATCGG
CCGCCACATGACGGGCTTCAAGGTGATCGTCGACAAGTCGACGGTGCCGGTCGGCACCGCGCGGCGCGTGCACGGCGTGG
TCGACGAGGCGCTTGCCGCACGCGGGCTCGCGGGCAGCGTCGCGCATCGCTTCTCGGTCGTGTCGAACCCGGAATTCCTG
AAGGAAGGCGCGGCGGTCGAGGACTTCATGCGCCCGGACCGGATCATCATCGGTGTCGACGACGACGAAACCGGCACGAT
CGCGCGCGAGAAGATGAAGAAGCTCTACGCGCCGTTCAACCGCAACCACGAACGCACGATCTACATGGACGTGCGTTCGG
CGGAATTCGCGAAGTATGCGGCGAACGCGATGCTCGCGACGCGCATCTCGTTCATGAACGAGATGTCGAATCTCGCCGAC
AAGGTCGGCGCCGACATCGAGGCCGTGCGCCGCGGGATCGGCTCCGATCCGCGCATCGGCTATCACTTCCTGTATGCCGG
CGTCGGCTACGGCGGCTCGTGCTTCCCGAAGGACGTGCAGGCGCTGATCCGCACCGCCGGCGAGAACGGCCAGCCGCTGC
GTATCCTGGAGGCTGTCGAGGCCGCCAACCATGCGCAGAAGGACGTGCTGATCGGCAAGATCGAGCAGCGCTTCGGCGCC
GACCTGACGGGCCGCGAGTTCGCGGTCTGGGGCCTCGCGTTCAAGCCGAACACCGACGACATGCGCGAGGCGCCGAGCCG
CCGCCTGATCGCCGCGCTGCTCGAACGCGGTGCGACCGTGCGCGCCTACGATCCGGTCGCCATCGACGAAGCGCGGCGCG
TGTTCGCGCTGGATTTCGGCGACGATGCGAAGGCGCTGGCGCGGCTGCATCTCGTCGACACGCAGGACGCCGCGGTCACG
GGCGCGGACGCCCTCGTGATCGTCACCGAATGGAAGGAATTCCGCAGCCCCGATTTCACGCGCCTGAAGGCCGAGCTGAA
GGCGCCGGTGATCTTCGACGGGCGCAACCTGTACGAGCCGGATGCGATGGCCGAGCTGGGCATCGACTATTACGCGATTG
GCCGGCCGTATGTCGATCCCCAGTCGTCCTCCCGTGGCTGA

Upstream 100 bases:

>100_bases
GCCGGGCTGATCCCGGCACGCGGAGCCAACGCGCTGCGGTTGCCGCCGGGCTCGTCCCGGCGGCCAAGTTAGTCAATTAC
CGGGAAGTACCGGAACATCT

Downstream 100 bases:

>100_bases
ACGTACGATGAATACTCTTCGCGAAGTCGTTCCGGTGCCGCGCGAGCAACTCGCGCGCTCGCGTGTGCTCGTCGTCGGCG
ACGTGATGCTCGACCGTTAC

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MKITIIGTGYVGLVTGACLAEIGHDVFCLDVDPRKIDILNNGGMPIHEPGLLDIIARNRTAGRLRFSTDIEASVAHGEIQ
FIAVGTPPDEDGSADLQYVLEAARNIGRHMTGFKVIVDKSTVPVGTARRVHGVVDEALAARGLAGSVAHRFSVVSNPEFL
KEGAAVEDFMRPDRIIIGVDDDETGTIAREKMKKLYAPFNRNHERTIYMDVRSAEFAKYAANAMLATRISFMNEMSNLAD
KVGADIEAVRRGIGSDPRIGYHFLYAGVGYGGSCFPKDVQALIRTAGENGQPLRILEAVEAANHAQKDVLIGKIEQRFGA
DLTGREFAVWGLAFKPNTDDMREAPSRRLIAALLERGATVRAYDPVAIDEARRVFALDFGDDAKALARLHLVDTQDAAVT
GADALVIVTEWKEFRSPDFTRLKAELKAPVIFDGRNLYEPDAMAELGIDYYAIGRPYVDPQSSSRG

Sequences:

>Translated_466_residues
MKITIIGTGYVGLVTGACLAEIGHDVFCLDVDPRKIDILNNGGMPIHEPGLLDIIARNRTAGRLRFSTDIEASVAHGEIQ
FIAVGTPPDEDGSADLQYVLEAARNIGRHMTGFKVIVDKSTVPVGTARRVHGVVDEALAARGLAGSVAHRFSVVSNPEFL
KEGAAVEDFMRPDRIIIGVDDDETGTIAREKMKKLYAPFNRNHERTIYMDVRSAEFAKYAANAMLATRISFMNEMSNLAD
KVGADIEAVRRGIGSDPRIGYHFLYAGVGYGGSCFPKDVQALIRTAGENGQPLRILEAVEAANHAQKDVLIGKIEQRFGA
DLTGREFAVWGLAFKPNTDDMREAPSRRLIAALLERGATVRAYDPVAIDEARRVFALDFGDDAKALARLHLVDTQDAAVT
GADALVIVTEWKEFRSPDFTRLKAELKAPVIFDGRNLYEPDAMAELGIDYYAIGRPYVDPQSSSRG
>Mature_466_residues
MKITIIGTGYVGLVTGACLAEIGHDVFCLDVDPRKIDILNNGGMPIHEPGLLDIIARNRTAGRLRFSTDIEASVAHGEIQ
FIAVGTPPDEDGSADLQYVLEAARNIGRHMTGFKVIVDKSTVPVGTARRVHGVVDEALAARGLAGSVAHRFSVVSNPEFL
KEGAAVEDFMRPDRIIIGVDDDETGTIAREKMKKLYAPFNRNHERTIYMDVRSAEFAKYAANAMLATRISFMNEMSNLAD
KVGADIEAVRRGIGSDPRIGYHFLYAGVGYGGSCFPKDVQALIRTAGENGQPLRILEAVEAANHAQKDVLIGKIEQRFGA
DLTGREFAVWGLAFKPNTDDMREAPSRRLIAALLERGATVRAYDPVAIDEARRVFALDFGDDAKALARLHLVDTQDAAVT
GADALVIVTEWKEFRSPDFTRLKAELKAPVIFDGRNLYEPDAMAELGIDYYAIGRPYVDPQSSSRG

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=471, Percent_Identity=34.1825902335456, Blast_Score=241, Evalue=8e-64,
Organism=Homo sapiens, GI296040438, Length=373, Percent_Identity=34.3163538873995, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI296040443, Length=315, Percent_Identity=35.5555555555556, Blast_Score=170, Evalue=2e-42,
Organism=Escherichia coli, GI1788340, Length=375, Percent_Identity=28, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI48994968, Length=424, Percent_Identity=25.4716981132075, Blast_Score=126, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17560350, Length=470, Percent_Identity=35.531914893617, Blast_Score=254, Evalue=1e-67,
Organism=Drosophila melanogaster, GI17136908, Length=472, Percent_Identity=35.3813559322034, Blast_Score=254, Evalue=1e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 50848; Mature: 50848

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITIIGTGYVGLVTGACLAEIGHDVFCLDVDPRKIDILNNGGMPIHEPGLLDIIARNRT
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCCCCCCCEEEEECCCC
AGRLRFSTDIEASVAHGEIQFIAVGTPPDEDGSADLQYVLEAARNIGRHMTGFKVIVDKS
CCEEEEECCCCEEEECCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECC
TVPVGTARRVHGVVDEALAARGLAGSVAHRFSVVSNPEFLKEGAAVEDFMRPDRIIIGVD
CCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHCCCCHHHHCCCCEEEEECC
DDETGTIAREKMKKLYAPFNRNHERTIYMDVRSAEFAKYAANAMLATRISFMNEMSNLAD
CCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVGADIEAVRRGIGSDPRIGYHFLYAGVGYGGSCFPKDVQALIRTAGENGQPLRILEAVE
HHCCCHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHH
AANHAQKDVLIGKIEQRFGADLTGREFAVWGLAFKPNTDDMREAPSRRLIAALLERGATV
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHCCHHHHHHHHHHCCCEE
RAYDPVAIDEARRVFALDFGDDAKALARLHLVDTQDAAVTGADALVIVTEWKEFRSPDFT
EEECCCCCCCCCEEEEEECCCCHHHHHEEEEECCCCCEEECCCEEEEEECHHHHCCCCHH
RLKAELKAPVIFDGRNLYEPDAMAELGIDYYAIGRPYVDPQSSSRG
HHHHHHCCCEEECCCCCCCCHHHHHHCCCEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MKITIIGTGYVGLVTGACLAEIGHDVFCLDVDPRKIDILNNGGMPIHEPGLLDIIARNRT
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCCCCCCCEEEEECCCC
AGRLRFSTDIEASVAHGEIQFIAVGTPPDEDGSADLQYVLEAARNIGRHMTGFKVIVDKS
CCEEEEECCCCEEEECCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECC
TVPVGTARRVHGVVDEALAARGLAGSVAHRFSVVSNPEFLKEGAAVEDFMRPDRIIIGVD
CCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHCCCCHHHHCCCCEEEEECC
DDETGTIAREKMKKLYAPFNRNHERTIYMDVRSAEFAKYAANAMLATRISFMNEMSNLAD
CCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVGADIEAVRRGIGSDPRIGYHFLYAGVGYGGSCFPKDVQALIRTAGENGQPLRILEAVE
HHCCCHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHH
AANHAQKDVLIGKIEQRFGADLTGREFAVWGLAFKPNTDDMREAPSRRLIAALLERGATV
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHCCHHHHHHHHHHCCCEE
RAYDPVAIDEARRVFALDFGDDAKALARLHLVDTQDAAVTGADALVIVTEWKEFRSPDFT
EEECCCCCCCCCEEEEEECCCCHHHHHEEEEECCCCCEEECCCEEEEEECHHHHCCCCHH
RLKAELKAPVIFDGRNLYEPDAMAELGIDYYAIGRPYVDPQSSSRG
HHHHHHCCCEEECCCCCCCCHHHHHHCCCEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]