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The map label for this gene is pcaR [H]

Identifier: 116688837

GI number: 116688837

Start: 913543

End: 914334

Strand: Direct

Name: pcaR [H]

Synonym: Bcen2424_0814

Alternate gene names: 116688837

Gene position: 913543-914334 (Clockwise)

Preceding gene: 116688835

Following gene: 116688838

Centisome position: 26.22

GC content: 70.33

Gene sequence:

>792_bases
ATGACACTTTCAACCATCGACGACACCACGATCGACGAGCGCAAGTTCGTCGTCGCGCTCGCGCGCGGGCTCGACCTGCT
GCGCGCCTTCCGGCCCGGCGAGACGATGCTGGGCAATCGCGATTTCGCGGAACGCACGGGGCTGCCGAAGGCGACGGTGA
ACCGGCTTGCCTATACGCTGACCGTGCTCGGCTATCTGCGCTACGACGAGACGCTCGGCAAGTATGCGCTGGACGCCGGT
GTGCTGTCGCTCGGCTACGCGCTGCTGTCGGGCTCGGGCACGATCGATCTCGCGCGGCCGCACATGCAGGCGCTCGCGCG
CGAGATCGGCGCGGCCGTGTCGCTCGGCTGCCGCGACGGGCTCGACATGATCTATCTGGAGACGATCCGCAGCGAGACCG
CGTTGACGCTCGGGCTCGCGCCCGGTTCGCGACTGTCGATGCTGACGAGCTCGATGGGGCGCGCGTACCTGGCCGTGCAG
CCGGAGGACGTGCGCCGCGCGCTCTATGCCGAACTGCACCGCGCGACCGGCGGCGCGGCCGACGCCGATGCGCTCGTCGC
CGCCGCGCAGCAGGCGGTGGCCGAATTCTCGGCGAGCGGCTGCTGCTATTCGTTTCGCGCGTGGCACACGGACGTGAACG
CGGCGGCCGTGCCGTTTCGCGAGCCGCGCGAGGGGCGCTGGCTGATCCTGAGCTGCAGCGGCCCGGCGTCGTCGATGGAC
GAAGACGTGTTTCGCACGCAGGTCGGGCCGCAACTGAAGGCGCTCGCGCAGCGGCTCGGGCAGACGGTCTGA

Upstream 100 bases:

>100_bases
GCGCTGCAGCGCTTGCTCCGGGCTGATGCCTGAAGTTCGCTTGACTTGCGTTCCGCTGTGCGGAACAATGTTTTGCAAAT
CGAACCCAGTGTAGCACCGG

Downstream 100 bases:

>100_bases
GAGCGACGAGCTCGCGGGTGTTGCCGTCGCGCGGCAACCGATCCGTGTGTGACGGATGTGGGCGCAGAGGCGATGCGGTG
CCGTTGCGTATTGCGCGACG

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MTLSTIDDTTIDERKFVVALARGLDLLRAFRPGETMLGNRDFAERTGLPKATVNRLAYTLTVLGYLRYDETLGKYALDAG
VLSLGYALLSGSGTIDLARPHMQALAREIGAAVSLGCRDGLDMIYLETIRSETALTLGLAPGSRLSMLTSSMGRAYLAVQ
PEDVRRALYAELHRATGGAADADALVAAAQQAVAEFSASGCCYSFRAWHTDVNAAAVPFREPREGRWLILSCSGPASSMD
EDVFRTQVGPQLKALAQRLGQTV

Sequences:

>Translated_263_residues
MTLSTIDDTTIDERKFVVALARGLDLLRAFRPGETMLGNRDFAERTGLPKATVNRLAYTLTVLGYLRYDETLGKYALDAG
VLSLGYALLSGSGTIDLARPHMQALAREIGAAVSLGCRDGLDMIYLETIRSETALTLGLAPGSRLSMLTSSMGRAYLAVQ
PEDVRRALYAELHRATGGAADADALVAAAQQAVAEFSASGCCYSFRAWHTDVNAAAVPFREPREGRWLILSCSGPASSMD
EDVFRTQVGPQLKALAQRLGQTV
>Mature_262_residues
TLSTIDDTTIDERKFVVALARGLDLLRAFRPGETMLGNRDFAERTGLPKATVNRLAYTLTVLGYLRYDETLGKYALDAGV
LSLGYALLSGSGTIDLARPHMQALAREIGAAVSLGCRDGLDMIYLETIRSETALTLGLAPGSRLSMLTSSMGRAYLAVQP
EDVRRALYAELHRATGGAADADALVAAAQQAVAEFSASGCCYSFRAWHTDVNAAAVPFREPREGRWLILSCSGPASSMDE
DVFRTQVGPQLKALAQRLGQTV

Specific function: Positive regulator of all genes within the pca regulon, pcaBDC, pcaIJ and pcaF. Also required for the chemotactic response to aromatic compounds [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI87082359, Length=233, Percent_Identity=27.4678111587983, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28266; Mature: 28134

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSTIDDTTIDERKFVVALARGLDLLRAFRPGETMLGNRDFAERTGLPKATVNRLAYTL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHHHCCCCHHHHHHHHHHH
TVLGYLRYDETLGKYALDAGVLSLGYALLSGSGTIDLARPHMQALAREIGAAVSLGCRDG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHCCCCCCC
LDMIYLETIRSETALTLGLAPGSRLSMLTSSMGRAYLAVQPEDVRRALYAELHRATGGAA
CHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHCCCCC
DADALVAAAQQAVAEFSASGCCYSFRAWHTDVNAAAVPFREPREGRWLILSCSGPASSMD
CHHHHHHHHHHHHHHHHCCCCEEEHHHHCCCCCCEECCCCCCCCCCEEEEECCCCCCCHH
EDVFRTQVGPQLKALAQRLGQTV
HHHHHHHCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
TLSTIDDTTIDERKFVVALARGLDLLRAFRPGETMLGNRDFAERTGLPKATVNRLAYTL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHHHCCCCHHHHHHHHHHH
TVLGYLRYDETLGKYALDAGVLSLGYALLSGSGTIDLARPHMQALAREIGAAVSLGCRDG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHCCCCCCC
LDMIYLETIRSETALTLGLAPGSRLSMLTSSMGRAYLAVQPEDVRRALYAELHRATGGAA
CHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHCCCCC
DADALVAAAQQAVAEFSASGCCYSFRAWHTDVNAAAVPFREPREGRWLILSCSGPASSMD
CHHHHHHHHHHHHHHHHCCCCEEEHHHHCCCCCCEECCCCCCCCCCEEEEECCCCCCCHH
EDVFRTQVGPQLKALAQRLGQTV
HHHHHHHCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083169 [H]