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The map label for this gene is pabB [H]

Identifier: 116688777

GI number: 116688777

Start: 844905

End: 846818

Strand: Direct

Name: pabB [H]

Synonym: Bcen2424_0754

Alternate gene names: 116688777

Gene position: 844905-846818 (Clockwise)

Preceding gene: 116688776

Following gene: 116688784

Centisome position: 24.25

GC content: 70.22

Gene sequence:

>1914_bases
ATGACTGAAGGCAACGAGAGCGCGTCGTTCGCGCTCTTGGACGATTGCGACTCGACCGCGTCCGCGCGGTCGAGTCGTTT
GTATTCGGGCTTCGTGCGCGAACGCGTGTGCACGGACCCGGCGCAGCTCGACGCCATCGATGCGGCGCTCGCGCAGGATC
TGCGCGACGGGCTGCATGCGGTCGTCGTCGGCGACTACGCATTCGGACGCAACCTGCAACGGGCGCAGCCGGGCCATGCC
CCGCTGCGCTTTTTGCTGTATGCGCGCTGCGAGCGGCTGTCGCGCGACGAAGTCGACGCGTGGCTCGCGCAGCAGGATGG
CGGCGGCACGCCGTCGATCGCGGGTGTCGCGCATGTCGCGAAGAGCGTGTCGCGCGATGCGTTCGACGCGGCGATCGGCG
CGGTGCACGACGCGCTGCGCGCGGGCGATTCGTATCAGGTCAACTACACGTACCGGCTGAATTTCGACGTGTTCGGCACG
CCGCTCGCGCTGTACCGGCGGCTGCGCGCGCGCCAGCCCGTGCGGTACGGCGCGCTGATCGCGCTGCCCGGCGGCGCGTG
GGTCGTATCGTGCTCGCCCGAGCTGTTCGTCGAGAAGCAGGGCGACGTGCTGCGCGCGCGGCCGATGAAGGGCACCGCGC
CGCGTTCGGCCGACCCGCGCGAAGACGCGGCGGCCGCTGCGTTCCTCGCGAGCGATCCGAAGAATCGCGCGGAGAACGTG
ATGATCGTCGACCTGCTGCGCAACGACGTGTCGCGGATCGCGCGCACGGGCACCGTCAAGGTGCCGGCGCTCTTCTCCGT
CGAGCCGTATGCGTCGGTGTGGCAGATGACGTCGACGGTCGAAGCCGGCTGGCGCGACGGCACGACGTTCGCGCAGATGC
TGCGCGCGCTGTTTCCGTGCGGATCGATCACCGGTGCGCCGAAGTACAAGACGATGGAATTGATCGACGCGATCGAGTCG
ACGCCGCGCGGGCTCTATACGGGTGCGATCGGCTGGCTCGATGCGCCGAAGGACGAGGCTGGGCAGGCAGGCGCTGCAGC
GTCCGGCGGCGTGGCCGGTTGCGGCGATTTCTGCCTGTCGGTCGCGATCCGGACGCTGACACTCGATGCGGTCGAGGGCG
ACGGCGACGACACGGACGGCACGGGCACCGCCACCGTCGGCCGGCGGCGCGGCACGATGGGCGTCGGCGCGGGCATCGTG
CTCGACAGCGTCGCGGCCGACGAATATGCGGAGTGCGAATTGAAAGCGCGATTCCTGACGGACGCCGACCCCGGCTTCCA
GTTGTTCGAAACGACGGCCGCCACGCGGGCGGACGGCATCCGCCATCTCGATCGTCATCTCGCGCGGCTGCAGCGCAGCG
CCGATGCATTCGGCTTCCGCTTCGATGCCGACGCATTGCGTCGCGAGATCGATGCACGCTGCGCGGCGCTCGACGGCGAC
GGCGCGTACCGGATGAAGCTCACGCTGGCGAAGGACGGGGCGACCGAGATCGTCGCGGCGCCGCTCAAGCCGCTGCCGGC
AGGGCCGGTCGGCGTGCTGCTGGCCTGCGAGCACGGCTTCGCGCCGACCCGCGCGAGCGATGCACTGCTGCTGCACAAGA
CCACGCGCCGGGCCGAATACGACCGCGCGTGGCAGGCCGCGGAGGCACTCGGCGGGTTCGACATGCTATTCGTCAACGAG
CGCGGCGAGGTGACGGAAGGCGGGCGCTCGAACTTGTTCGTGAAGCTCGACGGCCAGTGGGTGACGCCGCCGCTGGCGTC
CGGCGTGCTGCCGGGCGTGATGCGCGGGGTGCTGCTCGACGATCCCGCATTCGGGGCCGTGGAGCGCGTCGTGACCCGCG
ATGATCTGGCGCGCGCGCAGGGGCTGCTGCTGACCAATGCACTGCGTGGTGCGCTCGACACGGTGCTGAAGTGA

Upstream 100 bases:

>100_bases
CTCAAGCAGTTCGAGAAGTCGCTGGCCGAAGGCGGTGCGCGGCACAGCCCGCAGAGCAAAAGCTGGTTCGACCGTGTGAA
GAGCTTCTTCGAGTAACGGC

Downstream 100 bases:

>100_bases
CGAGGTGACGGAGCGGGCGCCGTATGCTTGCTCCGGTGCCTCGTTCATCCACGCGGCGCACAAACAAAAAAGCGCGGCGC
CCCGCAAAGGGCGCCGCGCT

Product: para-aminobenzoate synthase, subunit I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 637; Mature: 636

Protein sequence:

>637_residues
MTEGNESASFALLDDCDSTASARSSRLYSGFVRERVCTDPAQLDAIDAALAQDLRDGLHAVVVGDYAFGRNLQRAQPGHA
PLRFLLYARCERLSRDEVDAWLAQQDGGGTPSIAGVAHVAKSVSRDAFDAAIGAVHDALRAGDSYQVNYTYRLNFDVFGT
PLALYRRLRARQPVRYGALIALPGGAWVVSCSPELFVEKQGDVLRARPMKGTAPRSADPREDAAAAAFLASDPKNRAENV
MIVDLLRNDVSRIARTGTVKVPALFSVEPYASVWQMTSTVEAGWRDGTTFAQMLRALFPCGSITGAPKYKTMELIDAIES
TPRGLYTGAIGWLDAPKDEAGQAGAAASGGVAGCGDFCLSVAIRTLTLDAVEGDGDDTDGTGTATVGRRRGTMGVGAGIV
LDSVAADEYAECELKARFLTDADPGFQLFETTAATRADGIRHLDRHLARLQRSADAFGFRFDADALRREIDARCAALDGD
GAYRMKLTLAKDGATEIVAAPLKPLPAGPVGVLLACEHGFAPTRASDALLLHKTTRRAEYDRAWQAAEALGGFDMLFVNE
RGEVTEGGRSNLFVKLDGQWVTPPLASGVLPGVMRGVLLDDPAFGAVERVVTRDDLARAQGLLLTNALRGALDTVLK

Sequences:

>Translated_637_residues
MTEGNESASFALLDDCDSTASARSSRLYSGFVRERVCTDPAQLDAIDAALAQDLRDGLHAVVVGDYAFGRNLQRAQPGHA
PLRFLLYARCERLSRDEVDAWLAQQDGGGTPSIAGVAHVAKSVSRDAFDAAIGAVHDALRAGDSYQVNYTYRLNFDVFGT
PLALYRRLRARQPVRYGALIALPGGAWVVSCSPELFVEKQGDVLRARPMKGTAPRSADPREDAAAAAFLASDPKNRAENV
MIVDLLRNDVSRIARTGTVKVPALFSVEPYASVWQMTSTVEAGWRDGTTFAQMLRALFPCGSITGAPKYKTMELIDAIES
TPRGLYTGAIGWLDAPKDEAGQAGAAASGGVAGCGDFCLSVAIRTLTLDAVEGDGDDTDGTGTATVGRRRGTMGVGAGIV
LDSVAADEYAECELKARFLTDADPGFQLFETTAATRADGIRHLDRHLARLQRSADAFGFRFDADALRREIDARCAALDGD
GAYRMKLTLAKDGATEIVAAPLKPLPAGPVGVLLACEHGFAPTRASDALLLHKTTRRAEYDRAWQAAEALGGFDMLFVNE
RGEVTEGGRSNLFVKLDGQWVTPPLASGVLPGVMRGVLLDDPAFGAVERVVTRDDLARAQGLLLTNALRGALDTVLK
>Mature_636_residues
TEGNESASFALLDDCDSTASARSSRLYSGFVRERVCTDPAQLDAIDAALAQDLRDGLHAVVVGDYAFGRNLQRAQPGHAP
LRFLLYARCERLSRDEVDAWLAQQDGGGTPSIAGVAHVAKSVSRDAFDAAIGAVHDALRAGDSYQVNYTYRLNFDVFGTP
LALYRRLRARQPVRYGALIALPGGAWVVSCSPELFVEKQGDVLRARPMKGTAPRSADPREDAAAAAFLASDPKNRAENVM
IVDLLRNDVSRIARTGTVKVPALFSVEPYASVWQMTSTVEAGWRDGTTFAQMLRALFPCGSITGAPKYKTMELIDAIEST
PRGLYTGAIGWLDAPKDEAGQAGAAASGGVAGCGDFCLSVAIRTLTLDAVEGDGDDTDGTGTATVGRRRGTMGVGAGIVL
DSVAADEYAECELKARFLTDADPGFQLFETTAATRADGIRHLDRHLARLQRSADAFGFRFDADALRREIDARCAALDGDG
AYRMKLTLAKDGATEIVAAPLKPLPAGPVGVLLACEHGFAPTRASDALLLHKTTRRAEYDRAWQAAEALGGFDMLFVNER
GEVTEGGRSNLFVKLDGQWVTPPLASGVLPGVMRGVLLDDPAFGAVERVVTRDDLARAQGLLLTNALRGALDTVLK

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=322, Percent_Identity=35.0931677018634, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI1787518, Length=302, Percent_Identity=29.1390728476821, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1786809, Length=172, Percent_Identity=26.1627906976744, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320935, Length=303, Percent_Identity=29.7029702970297, Blast_Score=113, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6324361, Length=235, Percent_Identity=30.2127659574468, Blast_Score=95, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 67941; Mature: 67810

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEGNESASFALLDDCDSTASARSSRLYSGFVRERVCTDPAQLDAIDAALAQDLRDGLHA
CCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEE
VVVGDYAFGRNLQRAQPGHAPLRFLLYARCERLSRDEVDAWLAQQDGGGTPSIAGVAHVA
EEEECHHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHH
KSVSRDAFDAAIGAVHDALRAGDSYQVNYTYRLNFDVFGTPLALYRRLRARQPVRYGALI
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECEECCCHHHHHHHHHHCCCCCCCEEE
ALPGGAWVVSCSPELFVEKQGDVLRARPMKGTAPRSADPREDAAAAAFLASDPKNRAENV
EECCCCEEEECCCCEEEECCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHCCE
MIVDLLRNDVSRIARTGTVKVPALFSVEPYASVWQMTSTVEAGWRDGTTFAQMLRALFPC
EEHHHHHHHHHHHHHCCCEECCEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
GSITGAPKYKTMELIDAIESTPRGLYTGAIGWLDAPKDEAGQAGAAASGGVAGCGDFCLS
CCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
VAIRTLTLDAVEGDGDDTDGTGTATVGRRRGTMGVGAGIVLDSVAADEYAECELKARFLT
HHHHHHEEEEECCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHCCCHHHHEEEEEEEC
DADPGFQLFETTAATRADGIRHLDRHLARLQRSADAFGFRFDADALRREIDARCAALDGD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCEEECHHHHHHHHHHHHEEECCC
GAYRMKLTLAKDGATEIVAAPLKPLPAGPVGVLLACEHGFAPTRASDALLLHKTTRRAEY
CEEEEEEEEECCCCCCEEECCCCCCCCCCCEEEEEECCCCCCCCCCCEEEEEHHHHHHHH
DRAWQAAEALGGFDMLFVNERGEVTEGGRSNLFVKLDGQWVTPPLASGVLPGVMRGVLLD
HHHHHHHHHHCCEEEEEECCCCCCCCCCCCCEEEEECCEECCCHHHHHHHHHHHHHHHCC
DPAFGAVERVVTRDDLARAQGLLLTNALRGALDTVLK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TEGNESASFALLDDCDSTASARSSRLYSGFVRERVCTDPAQLDAIDAALAQDLRDGLHA
CCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEE
VVVGDYAFGRNLQRAQPGHAPLRFLLYARCERLSRDEVDAWLAQQDGGGTPSIAGVAHVA
EEEECHHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHH
KSVSRDAFDAAIGAVHDALRAGDSYQVNYTYRLNFDVFGTPLALYRRLRARQPVRYGALI
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECEECCCHHHHHHHHHHCCCCCCCEEE
ALPGGAWVVSCSPELFVEKQGDVLRARPMKGTAPRSADPREDAAAAAFLASDPKNRAENV
EECCCCEEEECCCCEEEECCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHCCE
MIVDLLRNDVSRIARTGTVKVPALFSVEPYASVWQMTSTVEAGWRDGTTFAQMLRALFPC
EEHHHHHHHHHHHHHCCCEECCEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
GSITGAPKYKTMELIDAIESTPRGLYTGAIGWLDAPKDEAGQAGAAASGGVAGCGDFCLS
CCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
VAIRTLTLDAVEGDGDDTDGTGTATVGRRRGTMGVGAGIVLDSVAADEYAECELKARFLT
HHHHHHEEEEECCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHCCCHHHHEEEEEEEC
DADPGFQLFETTAATRADGIRHLDRHLARLQRSADAFGFRFDADALRREIDARCAALDGD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCEEECHHHHHHHHHHHHEEECCC
GAYRMKLTLAKDGATEIVAAPLKPLPAGPVGVLLACEHGFAPTRASDALLLHKTTRRAEY
CEEEEEEEEECCCCCCEEECCCCCCCCCCCEEEEEECCCCCCCCCCCEEEEEHHHHHHHH
DRAWQAAEALGGFDMLFVNERGEVTEGGRSNLFVKLDGQWVTPPLASGVLPGVMRGVLLD
HHHHHHHHHHCCEEEEEECCCCCCCCCCCCCEEEEECCEECCCHHHHHHHHHHHHHHHCC
DPAFGAVERVVTRDDLARAQGLLLTNALRGALDTVLK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]