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The map label for this gene is hrcA [H]

Identifier: 116688768

GI number: 116688768

Start: 837186

End: 838208

Strand: Direct

Name: hrcA [H]

Synonym: Bcen2424_0745

Alternate gene names: 116688768

Gene position: 837186-838208 (Clockwise)

Preceding gene: 116688765

Following gene: 116688769

Centisome position: 24.03

GC content: 66.76

Gene sequence:

>1023_bases
ATGCTAGATCCTCGCGCACGAACCCTCCTGAAAACCCTGATCGAACGGTATATCGCCGACGGTCAGCCGGTCGGCTCGCG
CACGTTGTCCCGTTATTCCGGGCTCGAGCTGAGCCCGGCGACGATCCGCAACGTGATGTCCGACCTGGAGGAGCTCGGCC
TCGTGTCGAGCCCGCACACGTCGGCCGGCCGCGTGCCGACGCCGCGCGGGTACCGGCTGTTCGTCGATACGATGCTGACG
GTCGAGGCGCCGATCGACGCCGAGGCCGTCGCGCGCCAGGTGCAGAACACGCTGCAGGCCGGCGAGCCGCAGCAGCGGGT
GGTCGCGGCCGCCGCGAGCGTGCTGTCGAACCTGTCGCAGTTCGCGGGCGTCGTGCTGACGCCGCGCCGCAGCCACGTGT
TCAAGCAGATCGAGTTCATGCGCCTGTCCGACAAGCGCATCCTGCTGATCATTGTCACGCCCGAGGGCGACGTGCAGAAC
CGCATGCTCGCGACGCCGCGCGACTATTCGCCGTCGCAGCTGACCGAGGCGTCCAACTACATCAATGCGCATTTCGCCGG
CCTGTCGTTCGACGAGGTGCGCCGCCGCCTGCGCGACGAGATCGACCAGTTGCGCGGCGACATGACGACGCTGATGCACG
CGGCCGTGACGGCCAGCACCGAGGTGCCCGACACCGAGGACACCGTGCTGATTTCCGGCGAGCGCAACCTGCTCGAGGTG
GCGGATCTTTCTTCCGACATGGCGCGGCTGCGCAAGCTGTTCGACGTATTCGACCAAAAGACGGGCCTCCTGCAACTGCT
CGACGTGTCGAGCCACGCCCAAGGCGTGCAGATCTTCATCGGCGGCGAATCGACGCTCGTGCCGATCGAGGAAATGAGCG
TCGTCACCGCGCCGTACGAGGTGAACGGGCAGATCGTCGGCACGCTCGGCGTGATCGGCCCGACCCGCATGGCGTACAAC
CGCGTGATTCCGATCGTCGACATCACCGCGCGCCTGCTGTCGCTCACGCTGAGCCAGCAATAA

Upstream 100 bases:

>100_bases
AGAACCGGCTGTGCGCCGACGGGGCCGGATCGGGCCGCCCCGCGCAACGGTGGCCGACGGTACTCGCCGCAGTCGCGCGG
TTGCGCTAAAATTTTCCACC

Downstream 100 bases:

>100_bases
CCGGTGACCCGCCAGCGGTGGCGGACAATCGCCTGCCCGATCCCGCCCCGCTATCGTGCCGCGCCGCCGCTCGCGGCGAC
AGTCGGCCGAACGGCACGGG

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MLDPRARTLLKTLIERYIADGQPVGSRTLSRYSGLELSPATIRNVMSDLEELGLVSSPHTSAGRVPTPRGYRLFVDTMLT
VEAPIDAEAVARQVQNTLQAGEPQQRVVAAAASVLSNLSQFAGVVLTPRRSHVFKQIEFMRLSDKRILLIIVTPEGDVQN
RMLATPRDYSPSQLTEASNYINAHFAGLSFDEVRRRLRDEIDQLRGDMTTLMHAAVTASTEVPDTEDTVLISGERNLLEV
ADLSSDMARLRKLFDVFDQKTGLLQLLDVSSHAQGVQIFIGGESTLVPIEEMSVVTAPYEVNGQIVGTLGVIGPTRMAYN
RVIPIVDITARLLSLTLSQQ

Sequences:

>Translated_340_residues
MLDPRARTLLKTLIERYIADGQPVGSRTLSRYSGLELSPATIRNVMSDLEELGLVSSPHTSAGRVPTPRGYRLFVDTMLT
VEAPIDAEAVARQVQNTLQAGEPQQRVVAAAASVLSNLSQFAGVVLTPRRSHVFKQIEFMRLSDKRILLIIVTPEGDVQN
RMLATPRDYSPSQLTEASNYINAHFAGLSFDEVRRRLRDEIDQLRGDMTTLMHAAVTASTEVPDTEDTVLISGERNLLEV
ADLSSDMARLRKLFDVFDQKTGLLQLLDVSSHAQGVQIFIGGESTLVPIEEMSVVTAPYEVNGQIVGTLGVIGPTRMAYN
RVIPIVDITARLLSLTLSQQ
>Mature_340_residues
MLDPRARTLLKTLIERYIADGQPVGSRTLSRYSGLELSPATIRNVMSDLEELGLVSSPHTSAGRVPTPRGYRLFVDTMLT
VEAPIDAEAVARQVQNTLQAGEPQQRVVAAAASVLSNLSQFAGVVLTPRRSHVFKQIEFMRLSDKRILLIIVTPEGDVQN
RMLATPRDYSPSQLTEASNYINAHFAGLSFDEVRRRLRDEIDQLRGDMTTLMHAAVTASTEVPDTEDTVLISGERNLLEV
ADLSSDMARLRKLFDVFDQKTGLLQLLDVSSHAQGVQIFIGGESTLVPIEEMSVVTAPYEVNGQIVGTLGVIGPTRMAYN
RVIPIVDITARLLSLTLSQQ

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005104
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03444 DUF293; PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 37367; Mature: 37367

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDPRARTLLKTLIERYIADGQPVGSRTLSRYSGLELSPATIRNVMSDLEELGLVSSPHT
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCC
SAGRVPTPRGYRLFVDTMLTVEAPIDAEAVARQVQNTLQAGEPQQRVVAAAASVLSNLSQ
CCCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
FAGVVLTPRRSHVFKQIEFMRLSDKRILLIIVTPEGDVQNRMLATPRDYSPSQLTEASNY
HCCEEECCHHHHHHHHHHHHEECCCEEEEEEECCCCCCCCCEECCCCCCCHHHHHHHHHH
INAHFAGLSFDEVRRRLRDEIDQLRGDMTTLMHAAVTASTEVPDTEDTVLISGERNLLEV
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHH
ADLSSDMARLRKLFDVFDQKTGLLQLLDVSSHAQGVQIFIGGESTLVPIEEMSVVTAPYE
HHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCEEEHHHCEEEECCEE
VNGQIVGTLGVIGPTRMAYNRVIPIVDITARLLSLTLSQQ
ECCEEEEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLDPRARTLLKTLIERYIADGQPVGSRTLSRYSGLELSPATIRNVMSDLEELGLVSSPHT
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCC
SAGRVPTPRGYRLFVDTMLTVEAPIDAEAVARQVQNTLQAGEPQQRVVAAAASVLSNLSQ
CCCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
FAGVVLTPRRSHVFKQIEFMRLSDKRILLIIVTPEGDVQNRMLATPRDYSPSQLTEASNY
HCCEEECCHHHHHHHHHHHHEECCCEEEEEEECCCCCCCCCEECCCCCCCHHHHHHHHHH
INAHFAGLSFDEVRRRLRDEIDQLRGDMTTLMHAAVTASTEVPDTEDTVLISGERNLLEV
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHH
ADLSSDMARLRKLFDVFDQKTGLLQLLDVSSHAQGVQIFIGGESTLVPIEEMSVVTAPYE
HHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCEEEHHHCEEEECCEE
VNGQIVGTLGVIGPTRMAYNRVIPIVDITARLLSLTLSQQ
ECCEEEEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA