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The map label for this gene is tldD [H]

Identifier: 116688762

GI number: 116688762

Start: 824659

End: 826125

Strand: Reverse

Name: tldD [H]

Synonym: Bcen2424_0739

Alternate gene names: 116688762

Gene position: 826125-824659 (Counterclockwise)

Preceding gene: 116688763

Following gene: 116688761

Centisome position: 23.71

GC content: 68.51

Gene sequence:

>1467_bases
ATGAACATCATCGAACCCGGCATCCGCAACCTCGCGCTGGCGAAGGACATCCTGCTCACGCCGTACGGCCTCGACGAAAG
CCTGCTCACGCGCACGATCGCCGACATCTTCACGCATCGCGTCGACTACGCGGACCTGTATTTCCAGGCGACCCGCAGCG
AAGCGTGGAGCCTCGAGGAAGGCATCGTCAAATCGGGCAGCTTCAGCATCGACCAGGGCGTCGGCGTGCGCGCGGTCGCG
GGCGACCGCACCGCGTTCGCGTACTCGGACGACCTGTCGCCCGAGGCGATCGCGCAAGCCGCTGCCGCCACCAAGGCGAT
TGCGGCGGCCGGCGGCGGCCGCCAGAAGATCAAGGCCGCCTCGTCGCTGACGGGCATCTCGGGCCGCGACCTGTACCTGC
CGTCCGACCCGCTCGCGTCGCTCGACGCGACGGCCAAGGTCAAGCTGCTCGAACGCATCGAGCAGATGGCGCGCGGGCGC
GATCCGCGCATCACGCAGGTGATGGCCGGCCTCGCCGGCGAATACGACGTCGTGCTGGTCGCGCGCAGCGATGGCGCGCT
CGCGGCCGACATCCGGCCGCTGGTGCGCGTGTCGGTGACGGTGATCGCCGAGCAGAACGGCCGCCGCGAGATCGGCTCGG
GCGGCGGCGGCGGCCGCTTCGACTACGGCTACTTCACCGACGAAGTCCTGTCGCGCTACGTCGACGACGCCGTACACGCT
GCGCTCGTCAACCTCGACGCCCGCCCCGCGCCGGCCGGCGCGATGACGGTCGTGCTCGGGCCGGGCTGGCCGGGCGTGCT
GCTGCACGAGGCGATCGGCCACGGCCTCGAAGGCGACTTCAACCGCAAGGGTTCGTCCGCGTTCGCCGGCCGGATCGGCG
AGCAGGTCGCCGCGAAGGGCGTGACGGTGGTCGACGACGGTACGCTGCCGAACCGCCGCGGCTCGCTGAACATCGACGAC
GAGGGCAACCCGACGCAGTGCACGACGCTGATCGAGGACGGCATCCTGAAGGGCTACATCCAGGACACGCTGAACGCGCG
CCTGATGAAGATGCCGGTCACCGGCAATGCGCGGCGCGAGTCGTACGCGGCGCTGCCGATGCCGCGCATGACGAACACGT
ACATGCTGAACGGCGACAAGGACCCGCAGGAAATCATCGCATCGGTAAAGAACGGCCTGTACGCGGTGAACTTCGGCGGC
GGCCAGGTCGACATCACGAACGGCAAGTTCGTGTTCTCGGCGTCCGAGGCGTACATGATCGAGAACGGCAAGGTCACCTA
CCCGGTGAAGGGCGCGACGCTGATCGGCAGCGGCCCGGAATCGCTGAAATACGTGAGCATGATCGGCAACGACATGTCGC
TCGACACGGGCGTCGGCGTATGCGGCAAGGAAGGCCAGAGCGTGCCGGTCGGCGTCGGCCAGCCGACCCTGCGGATCGAC
AAGATGACGGTCGGCGGTACGGCATAA

Upstream 100 bases:

>100_bases
CCGCGTGCTGACCTGAATCCGCCGCACCGCTTGAAACGCCGCGCGGCCCACCCATCTGCCCGGCAGCACCCGACAACTTT
TTGAGAATCCCGATATCCGC

Downstream 100 bases:

>100_bases
CCGCATCGCGACGCAGACAATCCGCGCATTTTGACGAAAACGCGCGGATTGTCCGCATTTTTGAACGTCCCCGGTTGCCA
GCCGCGCGGGGACCGGGTAT

Product: peptidase U62, modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MNIIEPGIRNLALAKDILLTPYGLDESLLTRTIADIFTHRVDYADLYFQATRSEAWSLEEGIVKSGSFSIDQGVGVRAVA
GDRTAFAYSDDLSPEAIAQAAAATKAIAAAGGGRQKIKAASSLTGISGRDLYLPSDPLASLDATAKVKLLERIEQMARGR
DPRITQVMAGLAGEYDVVLVARSDGALAADIRPLVRVSVTVIAEQNGRREIGSGGGGGRFDYGYFTDEVLSRYVDDAVHA
ALVNLDARPAPAGAMTVVLGPGWPGVLLHEAIGHGLEGDFNRKGSSAFAGRIGEQVAAKGVTVVDDGTLPNRRGSLNIDD
EGNPTQCTTLIEDGILKGYIQDTLNARLMKMPVTGNARRESYAALPMPRMTNTYMLNGDKDPQEIIASVKNGLYAVNFGG
GQVDITNGKFVFSASEAYMIENGKVTYPVKGATLIGSGPESLKYVSMIGNDMSLDTGVGVCGKEGQSVPVGVGQPTLRID
KMTVGGTA

Sequences:

>Translated_488_residues
MNIIEPGIRNLALAKDILLTPYGLDESLLTRTIADIFTHRVDYADLYFQATRSEAWSLEEGIVKSGSFSIDQGVGVRAVA
GDRTAFAYSDDLSPEAIAQAAAATKAIAAAGGGRQKIKAASSLTGISGRDLYLPSDPLASLDATAKVKLLERIEQMARGR
DPRITQVMAGLAGEYDVVLVARSDGALAADIRPLVRVSVTVIAEQNGRREIGSGGGGGRFDYGYFTDEVLSRYVDDAVHA
ALVNLDARPAPAGAMTVVLGPGWPGVLLHEAIGHGLEGDFNRKGSSAFAGRIGEQVAAKGVTVVDDGTLPNRRGSLNIDD
EGNPTQCTTLIEDGILKGYIQDTLNARLMKMPVTGNARRESYAALPMPRMTNTYMLNGDKDPQEIIASVKNGLYAVNFGG
GQVDITNGKFVFSASEAYMIENGKVTYPVKGATLIGSGPESLKYVSMIGNDMSLDTGVGVCGKEGQSVPVGVGQPTLRID
KMTVGGTA
>Mature_488_residues
MNIIEPGIRNLALAKDILLTPYGLDESLLTRTIADIFTHRVDYADLYFQATRSEAWSLEEGIVKSGSFSIDQGVGVRAVA
GDRTAFAYSDDLSPEAIAQAAAATKAIAAAGGGRQKIKAASSLTGISGRDLYLPSDPLASLDATAKVKLLERIEQMARGR
DPRITQVMAGLAGEYDVVLVARSDGALAADIRPLVRVSVTVIAEQNGRREIGSGGGGGRFDYGYFTDEVLSRYVDDAVHA
ALVNLDARPAPAGAMTVVLGPGWPGVLLHEAIGHGLEGDFNRKGSSAFAGRIGEQVAAKGVTVVDDGTLPNRRGSLNIDD
EGNPTQCTTLIEDGILKGYIQDTLNARLMKMPVTGNARRESYAALPMPRMTNTYMLNGDKDPQEIIASVKNGLYAVNFGG
GQVDITNGKFVFSASEAYMIENGKVTYPVKGATLIGSGPESLKYVSMIGNDMSLDTGVGVCGKEGQSVPVGVGQPTLRID
KMTVGGTA

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=485, Percent_Identity=57.9381443298969, Blast_Score=540, Evalue=1e-155,
Organism=Escherichia coli, GI1790682, Length=444, Percent_Identity=24.0990990990991, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51392; Mature: 51392

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIIEPGIRNLALAKDILLTPYGLDESLLTRTIADIFTHRVDYADLYFQATRSEAWSLEE
CCCCCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCCHHHHEEEECCCHHHCHHH
GIVKSGSFSIDQGVGVRAVAGDRTAFAYSDDLSPEAIAQAAAATKAIAAAGGGRQKIKAA
HHHCCCCCCCCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
SSLTGISGRDLYLPSDPLASLDATAKVKLLERIEQMARGRDPRITQVMAGLAGEYDVVLV
HHCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEE
ARSDGALAADIRPLVRVSVTVIAEQNGRREIGSGGGGGRFDYGYFTDEVLSRYVDDAVHA
ECCCCCEECCCCCEEEEEEEEEECCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
ALVNLDARPAPAGAMTVVLGPGWPGVLLHEAIGHGLEGDFNRKGSSAFAGRIGEQVAAKG
HHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCC
VTVVDDGTLPNRRGSLNIDDEGNPTQCTTLIEDGILKGYIQDTLNARLMKMPVTGNARRE
CEEEECCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
SYAALPMPRMTNTYMLNGDKDPQEIIASVKNGLYAVNFGGGQVDITNGKFVFSASEAYMI
CEECCCCCCCCCEEEECCCCCHHHHHHHHHCCEEEEEECCCEEEEECCEEEEECCCEEEE
ENGKVTYPVKGATLIGSGPESLKYVSMIGNDMSLDTGVGVCGKEGQSVPVGVGQPTLRID
ECCEEEEEECCCEEECCCHHHHEEEEHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
KMTVGGTA
EEECCCCC
>Mature Secondary Structure
MNIIEPGIRNLALAKDILLTPYGLDESLLTRTIADIFTHRVDYADLYFQATRSEAWSLEE
CCCCCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCCHHHHEEEECCCHHHCHHH
GIVKSGSFSIDQGVGVRAVAGDRTAFAYSDDLSPEAIAQAAAATKAIAAAGGGRQKIKAA
HHHCCCCCCCCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
SSLTGISGRDLYLPSDPLASLDATAKVKLLERIEQMARGRDPRITQVMAGLAGEYDVVLV
HHCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEE
ARSDGALAADIRPLVRVSVTVIAEQNGRREIGSGGGGGRFDYGYFTDEVLSRYVDDAVHA
ECCCCCEECCCCCEEEEEEEEEECCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
ALVNLDARPAPAGAMTVVLGPGWPGVLLHEAIGHGLEGDFNRKGSSAFAGRIGEQVAAKG
HHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCC
VTVVDDGTLPNRRGSLNIDDEGNPTQCTTLIEDGILKGYIQDTLNARLMKMPVTGNARRE
CEEEECCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
SYAALPMPRMTNTYMLNGDKDPQEIIASVKNGLYAVNFGGGQVDITNGKFVFSASEAYMI
CEECCCCCCCCCEEEECCCCCHHHHHHHHHCCEEEEEECCCEEEEECCEEEEECCCEEEE
ENGKVTYPVKGATLIGSGPESLKYVSMIGNDMSLDTGVGVCGKEGQSVPVGVGQPTLRID
ECCEEEEEECCCEEECCCHHHHEEEEHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
KMTVGGTA
EEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]