Click here to switch to the map view.

The map label for this gene is hmp [H]

Identifier: 116688760

GI number: 116688760

Start: 821902

End: 823110

Strand: Direct

Name: hmp [H]

Synonym: Bcen2424_0737

Alternate gene names: 116688760

Gene position: 821902-823110 (Clockwise)

Preceding gene: 116688759

Following gene: 116688765

Centisome position: 23.59

GC content: 66.58

Gene sequence:

>1209_bases
ATGACCCACCTCACCGCTGACCAGATGGCCCGTGTGAAGGCCACCGCCCCCGTCCTCGCCGAGCACGGCGCGACGATCAC
GAAACATTTCTATCAGCGCATGTTCGCGCGTCATCCGGAACTGAAAAACCTGTTCAACCAGACGCACCAGAAGACCGGGA
GCCAGCCCGAGACGCTCGCGAAGGCCGTTTATGCGTATGCGGCGAACATCGACAACCTCGGTGTGCTGGGCGGCGCGGTG
TCGCGCATCTCGCACAAGCACGCCAGCCTGAACATCCGCCCCGAGCATTACCCGATCGTCGGCGAGAACCTGCTCGCATC
GATCGTCGAAGTGCTCGGCGACGCGGTCGATGCCGACACGCTCGAGGCATGGCGCGTCGCATACGGCCAGCTCGCACGGA
TCCTGATCGGCGCCGAGGCCGATCTGTACGCGAACGCTGCGTGGAGCGGCTTCCGCCCGTTCAGGGTCGCGCGCAAGGTG
CGTGAAAGCGACGAGATCACGTCGTTCTACCTGACGCCGGCCGACGGCGGCGCGGCGCCGACGTTCGAGCCGGGCCAGTA
CATCACGGTGAAGCGCTTCGTCGGCGATCTCGGCGTCGACCAGCCGCGCCAGTACAGTCTCTCGGATGCGCCGCACGGCA
AGTGGCTGCGCATCTCGGTGAAGCGTGAGGCCGGCAAGCCGGAAGCGATTCCGGCCGGCAAGGTGTCGACGCTGATGCAT
GACGGCGTCGAAGAGGGCGCGATCGTCGAAGTGACCGCGCCGATGGGCGACTTCTCGCTGAAGCGCGACGTGGATACGCC
GGTCGTGCTGATCTCGGGCGGCGTCGGCATCACGCCGATGATGTCGATGGCGTCGACGCTGATCGCCGCGGGCAGCCGGC
GCGACGTGCGGTTCATTCACGCCTGCCGTTCGGGCGCGGTGCACGCATTCCGCGACTGGTTGAACGATACCGTCGGCGAA
CACGCGAACGTCAAGCGTACGGTGCTGTACGAGCTGGTGGGTCCGAATGATCGCGCCGGCATCGACCACGACCTCGAAGG
GCGTCTCACGCCGGAGCGCGTGAAGCACTACGCGCTGGTACCGGATGCCGATTACTACATCTGCGGGCCGGTCGCGTTCA
TGAAGGCGCAGCGCGACGCGCTCGTCGCGCTCGGCGTCGCGCCGGAACGCGTGAACACCGAGATCTTCGGGTCGGGCGCG
CTCGAGTGA

Upstream 100 bases:

>100_bases
CGCTAGCCTGCCGTCCCATTTTTGCGCACTGCGACAATTTGCCCGGCGAGCGCTCTCCTTTAAACATGTATTCTTTGTGC
ATGTTTAAAGGAGAGCGAAC

Downstream 100 bases:

>100_bases
TGTGCGCACGGACGATCTCCGGCCAATAAAAAGCCCGGCGCGAGCCGGGCTTTTTCGTTGCGACGCAGGCGATCGGTCAG
TTCCCGCTACCGCGCGCGAC

Product: globin

Products: NA

Alternate protein names: Flavohemoglobin; Hemoglobin-like protein; Nitric oxide dioxygenase; NO oxygenase; NOD [H]

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MTHLTADQMARVKATAPVLAEHGATITKHFYQRMFARHPELKNLFNQTHQKTGSQPETLAKAVYAYAANIDNLGVLGGAV
SRISHKHASLNIRPEHYPIVGENLLASIVEVLGDAVDADTLEAWRVAYGQLARILIGAEADLYANAAWSGFRPFRVARKV
RESDEITSFYLTPADGGAAPTFEPGQYITVKRFVGDLGVDQPRQYSLSDAPHGKWLRISVKREAGKPEAIPAGKVSTLMH
DGVEEGAIVEVTAPMGDFSLKRDVDTPVVLISGGVGITPMMSMASTLIAAGSRRDVRFIHACRSGAVHAFRDWLNDTVGE
HANVKRTVLYELVGPNDRAGIDHDLEGRLTPERVKHYALVPDADYYICGPVAFMKAQRDALVALGVAPERVNTEIFGSGA
LE

Sequences:

>Translated_402_residues
MTHLTADQMARVKATAPVLAEHGATITKHFYQRMFARHPELKNLFNQTHQKTGSQPETLAKAVYAYAANIDNLGVLGGAV
SRISHKHASLNIRPEHYPIVGENLLASIVEVLGDAVDADTLEAWRVAYGQLARILIGAEADLYANAAWSGFRPFRVARKV
RESDEITSFYLTPADGGAAPTFEPGQYITVKRFVGDLGVDQPRQYSLSDAPHGKWLRISVKREAGKPEAIPAGKVSTLMH
DGVEEGAIVEVTAPMGDFSLKRDVDTPVVLISGGVGITPMMSMASTLIAAGSRRDVRFIHACRSGAVHAFRDWLNDTVGE
HANVKRTVLYELVGPNDRAGIDHDLEGRLTPERVKHYALVPDADYYICGPVAFMKAQRDALVALGVAPERVNTEIFGSGA
LE
>Mature_401_residues
THLTADQMARVKATAPVLAEHGATITKHFYQRMFARHPELKNLFNQTHQKTGSQPETLAKAVYAYAANIDNLGVLGGAVS
RISHKHASLNIRPEHYPIVGENLLASIVEVLGDAVDADTLEAWRVAYGQLARILIGAEADLYANAAWSGFRPFRVARKVR
ESDEITSFYLTPADGGAAPTFEPGQYITVKRFVGDLGVDQPRQYSLSDAPHGKWLRISVKREAGKPEAIPAGKVSTLMHD
GVEEGAIVEVTAPMGDFSLKRDVDTPVVLISGGVGITPMMSMASTLIAAGSRRDVRFIHACRSGAVHAFRDWLNDTVGEH
ANVKRTVLYELVGPNDRAGIDHDLEGRLTPERVKHYALVPDADYYICGPVAFMKAQRDALVALGVAPERVNTEIFGSGAL
E

Specific function: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a centra

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1788903, Length=399, Percent_Identity=42.1052631578947, Blast_Score=293, Evalue=1e-80,
Organism=Escherichia coli, GI1787658, Length=263, Percent_Identity=25.4752851711027, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321673, Length=396, Percent_Identity=37.1212121212121, Blast_Score=244, Evalue=1e-65,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR012292
- InterPro:   IPR009050
- InterPro:   IPR000971
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00042 Globin; PF00175 NAD_binding_1 [H]

EC number: =1.14.12.17 [H]

Molecular weight: Translated: 43714; Mature: 43583

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS01033 GLOBIN ; PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHLTADQMARVKATAPVLAEHGATITKHFYQRMFARHPELKNLFNQTHQKTGSQPETLA
CCCCCHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHH
KAVYAYAANIDNLGVLGGAVSRISHKHASLNIRPEHYPIVGENLLASIVEVLGDAVDADT
HHHHHHHCCCCCCHHHHHHHHHHHHHHCEEEECCCCCCCCCHHHHHHHHHHHHCCCCHHH
LEAWRVAYGQLARILIGAEADLYANAAWSGFRPFRVARKVRESDEITSFYLTPADGGAAP
HHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCC
TFEPGQYITVKRFVGDLGVDQPRQYSLSDAPHGKWLRISVKREAGKPEAIPAGKVSTLMH
CCCCCCEEEHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHH
DGVEEGAIVEVTAPMGDFSLKRDVDTPVVLISGGVGITPMMSMASTLIAAGSRRDVRFIH
CCCCCCCEEEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHH
ACRSGAVHAFRDWLNDTVGEHANVKRTVLYELVGPNDRAGIDHDLEGRLTPERVKHYALV
HHHCCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHEEEEC
PDADYYICGPVAFMKAQRDALVALGVAPERVNTEIFGSGALE
CCCCEEEECHHHHHHHCCCEEEEECCCCHHCCCEECCCCCCC
>Mature Secondary Structure 
THLTADQMARVKATAPVLAEHGATITKHFYQRMFARHPELKNLFNQTHQKTGSQPETLA
CCCCHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHH
KAVYAYAANIDNLGVLGGAVSRISHKHASLNIRPEHYPIVGENLLASIVEVLGDAVDADT
HHHHHHHCCCCCCHHHHHHHHHHHHHHCEEEECCCCCCCCCHHHHHHHHHHHHCCCCHHH
LEAWRVAYGQLARILIGAEADLYANAAWSGFRPFRVARKVRESDEITSFYLTPADGGAAP
HHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCC
TFEPGQYITVKRFVGDLGVDQPRQYSLSDAPHGKWLRISVKREAGKPEAIPAGKVSTLMH
CCCCCCEEEHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHH
DGVEEGAIVEVTAPMGDFSLKRDVDTPVVLISGGVGITPMMSMASTLIAAGSRRDVRFIH
CCCCCCCEEEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHH
ACRSGAVHAFRDWLNDTVGEHANVKRTVLYELVGPNDRAGIDHDLEGRLTPERVKHYALV
HHHCCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHEEEEC
PDADYYICGPVAFMKAQRDALVALGVAPERVNTEIFGSGALE
CCCCEEEECHHHHHHHCCCEEEEECCCCHHCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]