Click here to switch to the map view.

The map label for this gene is prc [C]

Identifier: 116688741

GI number: 116688741

Start: 797680

End: 799374

Strand: Reverse

Name: prc [C]

Synonym: Bcen2424_0718

Alternate gene names: 116688741

Gene position: 799374-797680 (Counterclockwise)

Preceding gene: 116688742

Following gene: 116688736

Centisome position: 22.94

GC content: 72.04

Gene sequence:

>1695_bases
ATGCGCGGGCCGCCGTCGTGTGGCGCGCCAACGGCTCGGCCGGCGCCGTCGCGGGTGTCGGCTACAATCGTCACCGCCCT
GCGCCGTCGCATGCCGACCACGCGCCGGCCGGGCAAACCCCTCCCTCGCCATCCGTCCGAGCGTGCGGTCCCGATGATGC
TTCCCATGCGTGTCGTTCGTCGCCTCGCCGCCTGCGCAGCCGCCGCAGCCGCGTTCCCGTATGCGTCGCTCGTCGGTGCG
CAACCGGCATCCGCGCCGCCTGCCGTTGCACCTGCCCCCGCTTCGGTGCCCGCCGCCCAACCGCCGTCACCCTGCCCGCC
CGACTGGGAACCGCAGCTCTGCGAACTCAAAGCGGCCGTCGAAGTGCTGAAGCGGCAACACCTGACCGACGTCGACATCG
GCGCGCTGCTCGACGCCGCGACCCACGAAGGCATCAAGACGCTGCCGTACGCGCGCTTCTTCAACGCGAAGGAGGAGCAG
GAACGACGCGACGACGAGCGGCGCGCACGCGACGGCACACCGGGCATCGGCATCGTGTTCGAGACGCGGCCCGACGGGCT
GCACATCATCGACGTGATTCCCGATGCGCCGGCCGAAAAGGCCGGTGTGCGGCCCGACGACCTCGTCGTCGCGATGAACG
ACAGGAGCGTCGTCGGCATCGACGGCGGCGAGTTGATGAAGCTCGCGAAGGGCGACGCGGGCGTGCCGCTGAAGCTCACG
GTGCAGCGCGGCCCGCAGCATGCGGTGCTGACCTTCGCGCCCGTGCGCGCGATCGTCAAGCCGCATCCGGCGACCGCGAA
GCGGCTCGACGGCGACATCCTGTACACGCGGCTGTCGAGCTTTCCGGAGTCGGCGGTCGGCGACTATATCGACGCGGTGC
AGGCCACGCGCCGCGCGGGCCCGCCGGTGAAGCAGATGATCCTCGACCTGCGCATCAACGGCGGCGGCGCGCTGAATGCG
GCGATCGGCATCACCGCGCTGTTCGCGGGACGCGACCGAACCGCGATGGTGACGGTCGAGCGCGACGGCACGCACCGCCG
CCGCTACACGACCAACTGGCCCGACTACGAACTGCCCGTCATGCACGGCCAGGACCCGCTCGCGCCGCTACAGGCCGACG
ACTGGTGGCGCACCGTGCCGCTCATCGTGCTCGTCGACGGCCAGAGCGCGTCGGCCGCCGAAGCGACCGCGGCGGCGCTG
AAGGATCTCGGCCGCGCGACACTGCTTGGCATGCCGACCTACGGGAAAGGGCTCGCGCAAACGGGCGTCGACCTGATCGA
CGGCACGCGCCTGAATTTCACGTTCGCGCGCAACCTGCGGCCGAACGGGTGCCCGATGGATGGTTACGGCGTCGTGCCGG
ACCGGCTCGTGCCGCCGCGCCGCGACGCGGACGTCGACGGCGTGCTGCTGTGGTACCGGGAAGTCGATCTCGCCCGCGCG
CCCTATGCGGACCGGCAGGCGCCCGACCCGTTCGCGCAGGTGCGCAAGGCCCGCCAGAAGCTGCGCGAAGCGCGCGTGCG
CGCGAAGGTCGATACGGCGAGGAGCGCGGCGCTGCCGCAGCGCGCATTCGGCACGGCGGCCGACTGGCAGCTCCGTCAGG
CGCTCAATGCCCTCGCCGGCCGCCCGGTGCAGACCATCGCCGCGCCCGCGCAACTGATGCCGGCGCAACCGGTCTGCGAG
CGCGGCGGCAACTGA

Upstream 100 bases:

>100_bases
CCGCGCACGATCCGGACGATCCGAACGCCGGCGCGCAGGTTTAAGCGCCACGCCATTTCGGTATCGAAGCAAAGCCGGCC
CGTCTGGGTCGGCTTTTTTT

Downstream 100 bases:

>100_bases
CGCGCCGGCCGCCCTCTTTCACCGAAACCCGAACCGCCGCCGCAGCACGACCAGCGCCGCGAGGCTCAGCACGGCCGCGA
ACATCAGATAGAAGCTCGGC

Product: peptidase S41

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 564; Mature: 564

Protein sequence:

>564_residues
MRGPPSCGAPTARPAPSRVSATIVTALRRRMPTTRRPGKPLPRHPSERAVPMMLPMRVVRRLAACAAAAAAFPYASLVGA
QPASAPPAVAPAPASVPAAQPPSPCPPDWEPQLCELKAAVEVLKRQHLTDVDIGALLDAATHEGIKTLPYARFFNAKEEQ
ERRDDERRARDGTPGIGIVFETRPDGLHIIDVIPDAPAEKAGVRPDDLVVAMNDRSVVGIDGGELMKLAKGDAGVPLKLT
VQRGPQHAVLTFAPVRAIVKPHPATAKRLDGDILYTRLSSFPESAVGDYIDAVQATRRAGPPVKQMILDLRINGGGALNA
AIGITALFAGRDRTAMVTVERDGTHRRRYTTNWPDYELPVMHGQDPLAPLQADDWWRTVPLIVLVDGQSASAAEATAAAL
KDLGRATLLGMPTYGKGLAQTGVDLIDGTRLNFTFARNLRPNGCPMDGYGVVPDRLVPPRRDADVDGVLLWYREVDLARA
PYADRQAPDPFAQVRKARQKLREARVRAKVDTARSAALPQRAFGTAADWQLRQALNALAGRPVQTIAAPAQLMPAQPVCE
RGGN

Sequences:

>Translated_564_residues
MRGPPSCGAPTARPAPSRVSATIVTALRRRMPTTRRPGKPLPRHPSERAVPMMLPMRVVRRLAACAAAAAAFPYASLVGA
QPASAPPAVAPAPASVPAAQPPSPCPPDWEPQLCELKAAVEVLKRQHLTDVDIGALLDAATHEGIKTLPYARFFNAKEEQ
ERRDDERRARDGTPGIGIVFETRPDGLHIIDVIPDAPAEKAGVRPDDLVVAMNDRSVVGIDGGELMKLAKGDAGVPLKLT
VQRGPQHAVLTFAPVRAIVKPHPATAKRLDGDILYTRLSSFPESAVGDYIDAVQATRRAGPPVKQMILDLRINGGGALNA
AIGITALFAGRDRTAMVTVERDGTHRRRYTTNWPDYELPVMHGQDPLAPLQADDWWRTVPLIVLVDGQSASAAEATAAAL
KDLGRATLLGMPTYGKGLAQTGVDLIDGTRLNFTFARNLRPNGCPMDGYGVVPDRLVPPRRDADVDGVLLWYREVDLARA
PYADRQAPDPFAQVRKARQKLREARVRAKVDTARSAALPQRAFGTAADWQLRQALNALAGRPVQTIAAPAQLMPAQPVCE
RGGN
>Mature_564_residues
MRGPPSCGAPTARPAPSRVSATIVTALRRRMPTTRRPGKPLPRHPSERAVPMMLPMRVVRRLAACAAAAAAFPYASLVGA
QPASAPPAVAPAPASVPAAQPPSPCPPDWEPQLCELKAAVEVLKRQHLTDVDIGALLDAATHEGIKTLPYARFFNAKEEQ
ERRDDERRARDGTPGIGIVFETRPDGLHIIDVIPDAPAEKAGVRPDDLVVAMNDRSVVGIDGGELMKLAKGDAGVPLKLT
VQRGPQHAVLTFAPVRAIVKPHPATAKRLDGDILYTRLSSFPESAVGDYIDAVQATRRAGPPVKQMILDLRINGGGALNA
AIGITALFAGRDRTAMVTVERDGTHRRRYTTNWPDYELPVMHGQDPLAPLQADDWWRTVPLIVLVDGQSASAAEATAAAL
KDLGRATLLGMPTYGKGLAQTGVDLIDGTRLNFTFARNLRPNGCPMDGYGVVPDRLVPPRRDADVDGVLLWYREVDLARA
PYADRQAPDPFAQVRKARQKLREARVRAKVDTARSAALPQRAFGTAADWQLRQALNALAGRPVQTIAAPAQLMPAQPVCE
RGGN

Specific function: Involved In The Cleavage Of A C-Terminal Peptide Of 11 Residues From The Precursor Form Of Penicillin-Binding Protein 3 (Pbp3). May Be Involved In Protection Of The Bacterium From Thermal And Osmotic Stresses. [C]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=180, Percent_Identity=33.8888888888889, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR002477 [H]

Pfam domain/function: PF00595 PDZ; PF03572 Peptidase_S41; PF01471 PG_binding_1 [H]

EC number: 3.4.21.102 [C]

Molecular weight: Translated: 60616; Mature: 60616

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGPPSCGAPTARPAPSRVSATIVTALRRRMPTTRRPGKPLPRHPSERAVPMMLPMRVVR
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
RLAACAAAAAAFPYASLVGAQPASAPPAVAPAPASVPAAQPPSPCPPDWEPQLCELKAAV
HHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
EVLKRQHLTDVDIGALLDAATHEGIKTLPYARFFNAKEEQERRDDERRARDGTPGIGIVF
HHHHHHCCCCCCHHHHHHHHHHCCCHHCCHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEE
ETRPDGLHIIDVIPDAPAEKAGVRPDDLVVAMNDRSVVGIDGGELMKLAKGDAGVPLKLT
ECCCCCEEEEEECCCCCHHHCCCCCCCEEEEECCCEEEECCCHHHHHHHCCCCCCCEEEE
VQRGPQHAVLTFAPVRAIVKPHPATAKRLDGDILYTRLSSFPESAVGDYIDAVQATRRAG
ECCCCCEEEEEEHHHHHHHCCCCCHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
PPVKQMILDLRINGGGALNAAIGITALFAGRDRTAMVTVERDGTHRRRYTTNWPDYELPV
CCHHHEEEEEEECCCCCCHHHHHEEHEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCCE
MHGQDPLAPLQADDWWRTVPLIVLVDGQSASAAEATAAALKDLGRATLLGMPTYGKGLAQ
ECCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCHHH
TGVDLIDGTRLNFTFARNLRPNGCPMDGYGVVPDRLVPPRRDADVDGVLLWYREVDLARA
CCCHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEHHHHHCC
PYADRQAPDPFAQVRKARQKLREARVRAKVDTARSAALPQRAFGTAADWQLRQALNALAG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHC
RPVQTIAAPAQLMPAQPVCERGGN
CCHHHHHCCHHHCCCCHHHHCCCC
>Mature Secondary Structure
MRGPPSCGAPTARPAPSRVSATIVTALRRRMPTTRRPGKPLPRHPSERAVPMMLPMRVVR
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
RLAACAAAAAAFPYASLVGAQPASAPPAVAPAPASVPAAQPPSPCPPDWEPQLCELKAAV
HHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
EVLKRQHLTDVDIGALLDAATHEGIKTLPYARFFNAKEEQERRDDERRARDGTPGIGIVF
HHHHHHCCCCCCHHHHHHHHHHCCCHHCCHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEE
ETRPDGLHIIDVIPDAPAEKAGVRPDDLVVAMNDRSVVGIDGGELMKLAKGDAGVPLKLT
ECCCCCEEEEEECCCCCHHHCCCCCCCEEEEECCCEEEECCCHHHHHHHCCCCCCCEEEE
VQRGPQHAVLTFAPVRAIVKPHPATAKRLDGDILYTRLSSFPESAVGDYIDAVQATRRAG
ECCCCCEEEEEEHHHHHHHCCCCCHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
PPVKQMILDLRINGGGALNAAIGITALFAGRDRTAMVTVERDGTHRRRYTTNWPDYELPV
CCHHHEEEEEEECCCCCCHHHHHEEHEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCCE
MHGQDPLAPLQADDWWRTVPLIVLVDGQSASAAEATAAALKDLGRATLLGMPTYGKGLAQ
ECCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCHHH
TGVDLIDGTRLNFTFARNLRPNGCPMDGYGVVPDRLVPPRRDADVDGVLLWYREVDLARA
CCCHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEHHHHHCC
PYADRQAPDPFAQVRKARQKLREARVRAKVDTARSAALPQRAFGTAADWQLRQALNALAG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHC
RPVQTIAAPAQLMPAQPVCERGGN
CCHHHHHCCHHHCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Cleavage of the C-terminal peptide from the precursor form of penicillin-binding protein 3 [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA