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The map label for this gene is pntB [H]

Identifier: 116688725

GI number: 116688725

Start: 781370

End: 782824

Strand: Direct

Name: pntB [H]

Synonym: Bcen2424_0702

Alternate gene names: 116688725

Gene position: 781370-782824 (Clockwise)

Preceding gene: 116688724

Following gene: 116688727

Centisome position: 22.43

GC content: 65.7

Gene sequence:

>1455_bases
ATGAGCATGAACGTCGTTACGCTGCTGTACCTCGTCGCGTCGGTGTGCTTCATCCAGGCGCTGAAGGGGCTGTCGAACCC
GAAGAGCGCGCGCCGCGGCAACCTGTTCGGGATGGTCGGGATGGCCATCGCGATCCTCACGACGATCGCGCTGATCGTCA
AGCAGGCCGCGTGGCTCGGCGCGAACCTGCCGCTCGGCCTCGCGCTCGTGCTCGGCGCGCTGATCGTCGGCGGAGGTGTC
GGGGCATTCGTCGCCGCGCGCGTCGAGATGACGAAGATGCCGGAACTCGTCGCGGCGATGCACTCGTTGATCGGTCTCGC
GGCCGTGTGCATCGCGTATGCGGTCGTGTCGGAGCCGGAAGCGTTCGGGCTCGTGCCGCAGGACGCGGTGTCGTCGAGCT
TCATCCCGTACGGCAACCGCGTCGAGCTGTTCATCGGCACGTTCGTCGGCGCGATCACGTTCTCCGGGTCGGTGATCGCG
TTCGGCAAGCTGTCGGGCAAGTACAAGTTCCGGCTGTTCCAGGGCGCGCCGGTCGTGTATGCCGGCCAGCACCTGATCAA
CCTGATGCTCGCGATCGCGATGCTCGGCTTCGGCATCCTGTTCTTCATCACGCAGGCGTGGCTGCCGTTCATCATCATGA
CGGCGATCGCGTTCGTGCTCGGCGTGCTGATCATCATCCCGATCGGCGGCGCGGACATGCCGGTGGTCGTGTCGATGCTG
AACTCGTACTCGGGCTGGGCCGCGGCCGGCATCGGCTTCTCGCTGAACAACGCGATGCTGATCATCGCCGGCTCGCTGGT
CGGCTCGTCGGGTGCGATCCTGTCGTACATCATGTGCCACGCGATGAACCGCTCGTTCTTCAACGTGATCCTCGGCGGGT
TCGGCGGCGAAGCGGCGGCCGGCGGCGCGGCGGGCGCGCAGGAGCAGCGGCCGGTGAAGTCGGGCTCGGCCGACGACGCG
GCGTTCATGCTCGGCAACGCGGAATCGGTCGTGATCGTGCCGGGTTACGGCCTTGCCGTCGCCCGGGCGCAGCACGCGCT
GAAGGAGCTGACCGACAAGCTGGTCGAGAAGGGCATCGACGTGAAGTACGCGATCCACCCGGTCGCGGGGCGGATGCCGG
GCCACATGAACGTGCTGCTCGCGGAAGCGGAAGTGCCGTACGAGATCGTGCACGAGATGGAGGACATCAACGGCGAATTC
GGCCAGGTGGACGTGGTGCTCGTGCTCGGCGCGAACGACGTCGTGAACCCGGCCGCGAAGAACGATCCGAAATCGCCGAT
CGCGGGGATGCCGATCATCGAGGCGTACAAGGCGCGCACGGTGATCGTCAACAAGCGCTCGATGGCGGCCGGCTACGCGG
GCCTCGACAACTACCTGTTCTACATGGACAAGACGATGATGGTGTTCGGCGATGCGAAGAAGGTCATCGAGGACATGGTG
AAGGCCGTCGAATAA

Upstream 100 bases:

>100_bases
CCGTCAACGTGTTCGGCGGCTTTCTCGTGACGAGGCGCATGCTCGAGATGTTCCGCAAGAAGGAGCCCAAGCGTATCGAG
GGCAGCAAGGAGGGTGCGCG

Downstream 100 bases:

>100_bases
CGCACGCCCCGGCTACGCGGTGCCCGCTTCGATGCGCGGGCGCAGCGCTCCCGGCAGGCCCGACCGGTACAAGAAGCCGG
CCGGGCCTTTTTCATGGGGC

Product: NAD(P) transhydrogenase, beta subunit

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Proton-translocating transhydrogenase NADP(H)-binding component; Pyridine nucleotide transhydrogenase subunit beta; dIII [H]

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MSMNVVTLLYLVASVCFIQALKGLSNPKSARRGNLFGMVGMAIAILTTIALIVKQAAWLGANLPLGLALVLGALIVGGGV
GAFVAARVEMTKMPELVAAMHSLIGLAAVCIAYAVVSEPEAFGLVPQDAVSSSFIPYGNRVELFIGTFVGAITFSGSVIA
FGKLSGKYKFRLFQGAPVVYAGQHLINLMLAIAMLGFGILFFITQAWLPFIIMTAIAFVLGVLIIIPIGGADMPVVVSML
NSYSGWAAAGIGFSLNNAMLIIAGSLVGSSGAILSYIMCHAMNRSFFNVILGGFGGEAAAGGAAGAQEQRPVKSGSADDA
AFMLGNAESVVIVPGYGLAVARAQHALKELTDKLVEKGIDVKYAIHPVAGRMPGHMNVLLAEAEVPYEIVHEMEDINGEF
GQVDVVLVLGANDVVNPAAKNDPKSPIAGMPIIEAYKARTVIVNKRSMAAGYAGLDNYLFYMDKTMMVFGDAKKVIEDMV
KAVE

Sequences:

>Translated_484_residues
MSMNVVTLLYLVASVCFIQALKGLSNPKSARRGNLFGMVGMAIAILTTIALIVKQAAWLGANLPLGLALVLGALIVGGGV
GAFVAARVEMTKMPELVAAMHSLIGLAAVCIAYAVVSEPEAFGLVPQDAVSSSFIPYGNRVELFIGTFVGAITFSGSVIA
FGKLSGKYKFRLFQGAPVVYAGQHLINLMLAIAMLGFGILFFITQAWLPFIIMTAIAFVLGVLIIIPIGGADMPVVVSML
NSYSGWAAAGIGFSLNNAMLIIAGSLVGSSGAILSYIMCHAMNRSFFNVILGGFGGEAAAGGAAGAQEQRPVKSGSADDA
AFMLGNAESVVIVPGYGLAVARAQHALKELTDKLVEKGIDVKYAIHPVAGRMPGHMNVLLAEAEVPYEIVHEMEDINGEF
GQVDVVLVLGANDVVNPAAKNDPKSPIAGMPIIEAYKARTVIVNKRSMAAGYAGLDNYLFYMDKTMMVFGDAKKVIEDMV
KAVE
>Mature_483_residues
SMNVVTLLYLVASVCFIQALKGLSNPKSARRGNLFGMVGMAIAILTTIALIVKQAAWLGANLPLGLALVLGALIVGGGVG
AFVAARVEMTKMPELVAAMHSLIGLAAVCIAYAVVSEPEAFGLVPQDAVSSSFIPYGNRVELFIGTFVGAITFSGSVIAF
GKLSGKYKFRLFQGAPVVYAGQHLINLMLAIAMLGFGILFFITQAWLPFIIMTAIAFVLGVLIIIPIGGADMPVVVSMLN
SYSGWAAAGIGFSLNNAMLIIAGSLVGSSGAILSYIMCHAMNRSFFNVILGGFGGEAAAGGAAGAQEQRPVKSGSADDAA
FMLGNAESVVIVPGYGLAVARAQHALKELTDKLVEKGIDVKYAIHPVAGRMPGHMNVLLAEAEVPYEIVHEMEDINGEFG
QVDVVLVLGANDVVNPAAKNDPKSPIAGMPIIEAYKARTVIVNKRSMAAGYAGLDNYLFYMDKTMMVFGDAKKVIEDMVK
AVE

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=493, Percent_Identity=45.4361054766734, Blast_Score=397, Evalue=1e-110,
Organism=Homo sapiens, GI122939153, Length=493, Percent_Identity=45.4361054766734, Blast_Score=397, Evalue=1e-110,
Organism=Escherichia coli, GI1787886, Length=488, Percent_Identity=49.7950819672131, Blast_Score=451, Evalue=1e-128,
Organism=Caenorhabditis elegans, GI17550456, Length=481, Percent_Identity=42.8274428274428, Blast_Score=358, Evalue=4e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 50704; Mature: 50572

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMNVVTLLYLVASVCFIQALKGLSNPKSARRGNLFGMVGMAIAILTTIALIVKQAAWLG
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
ANLPLGLALVLGALIVGGGVGAFVAARVEMTKMPELVAAMHSLIGLAAVCIAYAVVSEPE
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
AFGLVPQDAVSSSFIPYGNRVELFIGTFVGAITFSGSVIAFGKLSGKYKFRLFQGAPVVY
HCCCCCHHHHCCCCCCCCCEEEEHHHHHHHHHHCCCCEEEEEECCCEEEEEEEECCCEEE
AGQHLINLMLAIAMLGFGILFFITQAWLPFIIMTAIAFVLGVLIIIPIGGADMPVVVSML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHH
NSYSGWAAAGIGFSLNNAMLIIAGSLVGSSGAILSYIMCHAMNRSFFNVILGGFGGEAAA
HCCCCCCHHCCCEECCCEEEEEEECCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCCCC
GGAAGAQEQRPVKSGSADDAAFMLGNAESVVIVPGYGLAVARAQHALKELTDKLVEKGID
CCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
VKYAIHPVAGRMPGHMNVLLAEAEVPYEIVHEMEDINGEFGQVDVVLVLGANDVVNPAAK
EEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCC
NDPKSPIAGMPIIEAYKARTVIVNKRSMAAGYAGLDNYLFYMDKTMMVFGDAKKVIEDMV
CCCCCCCCCCCHHHHHCCEEEEEECHHHHCCCCCHHHHHHHCCCCCEEECCHHHHHHHHH
KAVE
HHCC
>Mature Secondary Structure 
SMNVVTLLYLVASVCFIQALKGLSNPKSARRGNLFGMVGMAIAILTTIALIVKQAAWLG
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
ANLPLGLALVLGALIVGGGVGAFVAARVEMTKMPELVAAMHSLIGLAAVCIAYAVVSEPE
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
AFGLVPQDAVSSSFIPYGNRVELFIGTFVGAITFSGSVIAFGKLSGKYKFRLFQGAPVVY
HCCCCCHHHHCCCCCCCCCEEEEHHHHHHHHHHCCCCEEEEEECCCEEEEEEEECCCEEE
AGQHLINLMLAIAMLGFGILFFITQAWLPFIIMTAIAFVLGVLIIIPIGGADMPVVVSML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHH
NSYSGWAAAGIGFSLNNAMLIIAGSLVGSSGAILSYIMCHAMNRSFFNVILGGFGGEAAA
HCCCCCCHHCCCEECCCEEEEEEECCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCCCC
GGAAGAQEQRPVKSGSADDAAFMLGNAESVVIVPGYGLAVARAQHALKELTDKLVEKGID
CCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
VKYAIHPVAGRMPGHMNVLLAEAEVPYEIVHEMEDINGEFGQVDVVLVLGANDVVNPAAK
EEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCC
NDPKSPIAGMPIIEAYKARTVIVNKRSMAAGYAGLDNYLFYMDKTMMVFGDAKKVIEDMV
CCCCCCCCCCCHHHHHCCEEEEEECHHHHCCCCCHHHHHHHCCCCCEEECCHHHHHHHHH
KAVE
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]