| Definition | Burkholderia cenocepacia HI2424 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_008542 |
| Length | 3,483,902 |
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The map label for this gene is gno [H]
Identifier: 116688664
GI number: 116688664
Start: 714186
End: 714959
Strand: Direct
Name: gno [H]
Synonym: Bcen2424_0641
Alternate gene names: 116688664
Gene position: 714186-714959 (Clockwise)
Preceding gene: 116688662
Following gene: 116688665
Centisome position: 20.5
GC content: 68.86
Gene sequence:
>774_bases ATGACCCATGCGCTTGACCGATTCCGCCTCGACGGCCGCCGCGCGCTGATTACCGGTTCCGGCCGCGGGATCGGGCTGAC GCTCGCCCGCGGGCTCGCGGAAGCGGGCGCGGCGATCGTCATCAACGATCGCAATGAAGAGAAGGCCGCGACGCTCGCGC GCCAGTTCCGCGACGAAGGCTTCGCGGCCGACCATGCGGTGTTCGACGTGGCCGAGCACGCGCAGGTACGTGCGGCGATC GACGACTTCGAGACACGCGTCGGCGCGATCGACATCCTCGTGAACAACGCGGGCATCCAGCGCCGCGCGCCGCTCGACGC TTTCGACCCGGACGACTGGCATGCACTGATGCGCGTGAATCTCGACGGCGTGTTCAACGTCGCGCAGGCCGTCGCGCGGC ACATGATCGCGCGCCGCCACGGCAAGATCATCAACGTCTGCTCGGTGCAGAGCGAACTCGCGCGGCCGACGATCGCGCCG TATGCGGCGACCAAGGGCGCGGTGCGGATGCTGACCAAGGGGATGTGCGCCGACTGGGCGCGTCACGGCATCCAGGCGAA CGGCCTCGCGCCCGGCTATTTCGAAACCGAACTGAATCGCGCGCTGGTCGACGACGCGGCGTTTTCGGACTGGCTGTGCA AGCGCACGCCGGCCGGTCGTTGGGGGCAGGTCGACGAGCTGTGCGGCGCGGCGATCTTCCTCGCGTCGGCCGCGTCCGAT TTCGTGAACGGCCAGACGCTGTTCGTCGACGGCGGGCTGACCAGTGCCGTCTAA
Upstream 100 bases:
>100_bases AAAAGACCATTGGCGCGGGCCGGGCCGGCGACCGAAGATAGCGTGAACGCGAGACCGGCCGCGACAAGGCAGCCGGCTCG ACTGGCACGAGGAGACATCC
Downstream 100 bases:
>100_bases CCAGGAGCGCGTCATGCGGTTGCGTTGCATGTGTGTGGTGATCCACGGGCCGAACGACCTGCGGGTCGAGGAGCAGGACG CGGGCGAGATCGGCCCGGGC
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 5-keto-D-gluconate 5-reductase [H]
Number of amino acids: Translated: 257; Mature: 256
Protein sequence:
>257_residues MTHALDRFRLDGRRALITGSGRGIGLTLARGLAEAGAAIVINDRNEEKAATLARQFRDEGFAADHAVFDVAEHAQVRAAI DDFETRVGAIDILVNNAGIQRRAPLDAFDPDDWHALMRVNLDGVFNVAQAVARHMIARRHGKIINVCSVQSELARPTIAP YAATKGAVRMLTKGMCADWARHGIQANGLAPGYFETELNRALVDDAAFSDWLCKRTPAGRWGQVDELCGAAIFLASAASD FVNGQTLFVDGGLTSAV
Sequences:
>Translated_257_residues MTHALDRFRLDGRRALITGSGRGIGLTLARGLAEAGAAIVINDRNEEKAATLARQFRDEGFAADHAVFDVAEHAQVRAAI DDFETRVGAIDILVNNAGIQRRAPLDAFDPDDWHALMRVNLDGVFNVAQAVARHMIARRHGKIINVCSVQSELARPTIAP YAATKGAVRMLTKGMCADWARHGIQANGLAPGYFETELNRALVDDAAFSDWLCKRTPAGRWGQVDELCGAAIFLASAASD FVNGQTLFVDGGLTSAV >Mature_256_residues THALDRFRLDGRRALITGSGRGIGLTLARGLAEAGAAIVINDRNEEKAATLARQFRDEGFAADHAVFDVAEHAQVRAAID DFETRVGAIDILVNNAGIQRRAPLDAFDPDDWHALMRVNLDGVFNVAQAVARHMIARRHGKIINVCSVQSELARPTIAPY AATKGAVRMLTKGMCADWARHGIQANGLAPGYFETELNRALVDDAAFSDWLCKRTPAGRWGQVDELCGAAIFLASAASDF VNGQTLFVDGGLTSAV
Specific function: Involved in the non-phosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate. Dependent on NADP, almost inactive with NAD [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI7705925, Length=246, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=1e-26, Organism=Homo sapiens, GI19923817, Length=254, Percent_Identity=29.9212598425197, Blast_Score=112, Evalue=4e-25, Organism=Homo sapiens, GI40254992, Length=239, Percent_Identity=30.9623430962343, Blast_Score=109, Evalue=2e-24, Organism=Homo sapiens, GI15277342, Length=254, Percent_Identity=29.9212598425197, Blast_Score=102, Evalue=4e-22, Organism=Homo sapiens, GI66933014, Length=251, Percent_Identity=31.0756972111554, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI32483357, Length=251, Percent_Identity=27.8884462151394, Blast_Score=99, Evalue=4e-21, Organism=Homo sapiens, GI4503301, Length=224, Percent_Identity=25.8928571428571, Blast_Score=96, Evalue=4e-20, Organism=Homo sapiens, GI59889578, Length=232, Percent_Identity=31.4655172413793, Blast_Score=95, Evalue=8e-20, Organism=Homo sapiens, GI10190704, Length=245, Percent_Identity=28.5714285714286, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI4504505, Length=230, Percent_Identity=30.4347826086957, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI20149619, Length=195, Percent_Identity=29.7435897435897, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI210032110, Length=207, Percent_Identity=27.0531400966184, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI7706318, Length=191, Percent_Identity=28.2722513089005, Blast_Score=81, Evalue=8e-16, Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=25.2032520325203, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=25.6, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI4758504, Length=260, Percent_Identity=28.8461538461538, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI7705855, Length=199, Percent_Identity=27.6381909547739, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI4557649, Length=203, Percent_Identity=28.0788177339901, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI31542939, Length=213, Percent_Identity=25.3521126760563, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI226371731, Length=201, Percent_Identity=26.3681592039801, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI209862901, Length=197, Percent_Identity=28.4263959390863, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI19923983, Length=197, Percent_Identity=28.4263959390863, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI4503817, Length=180, Percent_Identity=26.6666666666667, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI109715829, Length=208, Percent_Identity=27.4038461538462, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI142976729, Length=193, Percent_Identity=25.3886010362694, Blast_Score=65, Evalue=7e-11, Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=56.3492063492063, Blast_Score=301, Evalue=4e-83, Organism=Escherichia coli, GI87082160, Length=249, Percent_Identity=36.9477911646586, Blast_Score=165, Evalue=2e-42, Organism=Escherichia coli, GI1789208, Length=254, Percent_Identity=40.5511811023622, Blast_Score=162, Evalue=1e-41, Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=34.1463414634146, Blast_Score=149, Evalue=3e-37, Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=36.8627450980392, Blast_Score=132, Evalue=2e-32, Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=34.4262295081967, Blast_Score=128, Evalue=4e-31, Organism=Escherichia coli, GI1787905, Length=247, Percent_Identity=32.7935222672065, Blast_Score=116, Evalue=1e-27, Organism=Escherichia coli, GI1786812, Length=253, Percent_Identity=29.6442687747036, Blast_Score=106, Evalue=1e-24, Organism=Escherichia coli, GI2367175, Length=247, Percent_Identity=30.7692307692308, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI2367365, Length=242, Percent_Identity=30.5785123966942, Blast_Score=83, Evalue=1e-17, Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=27.5303643724696, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1789057, Length=256, Percent_Identity=26.171875, Blast_Score=77, Evalue=9e-16, Organism=Escherichia coli, GI1787820, Length=178, Percent_Identity=26.9662921348315, Blast_Score=69, Evalue=2e-13, Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=30.9236947791165, Blast_Score=119, Evalue=1e-27, Organism=Caenorhabditis elegans, GI17555706, Length=250, Percent_Identity=31.6, Blast_Score=117, Evalue=6e-27, Organism=Caenorhabditis elegans, GI17560676, Length=245, Percent_Identity=27.7551020408163, Blast_Score=107, Evalue=7e-24, Organism=Caenorhabditis elegans, GI17561402, Length=250, Percent_Identity=28.4, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17531453, Length=265, Percent_Identity=30.188679245283, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI71994604, Length=245, Percent_Identity=31.8367346938775, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17562906, Length=263, Percent_Identity=28.8973384030418, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI71994600, Length=246, Percent_Identity=30.4878048780488, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI17562904, Length=265, Percent_Identity=30.188679245283, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17536025, Length=253, Percent_Identity=28.4584980237154, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17536651, Length=253, Percent_Identity=28.0632411067194, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17560220, Length=262, Percent_Identity=29.0076335877863, Blast_Score=100, Evalue=8e-22, Organism=Caenorhabditis elegans, GI17560150, Length=263, Percent_Identity=29.6577946768061, Blast_Score=100, Evalue=8e-22, Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=29.2682926829268, Blast_Score=100, Evalue=9e-22, Organism=Caenorhabditis elegans, GI17562910, Length=272, Percent_Identity=28.6764705882353, Blast_Score=97, Evalue=8e-21, Organism=Caenorhabditis elegans, GI17560332, Length=268, Percent_Identity=29.1044776119403, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=27.5471698113208, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17561272, Length=255, Percent_Identity=29.0196078431373, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI193204405, Length=261, Percent_Identity=28.3524904214559, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=29.2307692307692, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI17538480, Length=264, Percent_Identity=28.4090909090909, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=28.4615384615385, Blast_Score=91, Evalue=8e-19, Organism=Caenorhabditis elegans, GI17565030, Length=263, Percent_Identity=30.4182509505703, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=29.1666666666667, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17568967, Length=212, Percent_Identity=31.1320754716981, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17563726, Length=267, Percent_Identity=27.3408239700375, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=27.5471698113208, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=29.1666666666667, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI72000259, Length=269, Percent_Identity=27.1375464684015, Blast_Score=86, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17564282, Length=204, Percent_Identity=29.4117647058824, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17538182, Length=262, Percent_Identity=29.3893129770992, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI193203117, Length=162, Percent_Identity=28.3950617283951, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI193203115, Length=158, Percent_Identity=29.1139240506329, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI32563809, Length=220, Percent_Identity=25, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17507613, Length=220, Percent_Identity=25.4545454545455, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17508895, Length=193, Percent_Identity=27.4611398963731, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI71997099, Length=267, Percent_Identity=28.8389513108614, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI115534660, Length=197, Percent_Identity=27.4111675126904, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI71982365, Length=195, Percent_Identity=26.6666666666667, Blast_Score=67, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=190, Percent_Identity=27.3684210526316, Blast_Score=74, Evalue=2e-14, Organism=Saccharomyces cerevisiae, GI6324126, Length=252, Percent_Identity=24.2063492063492, Blast_Score=73, Evalue=4e-14, Organism=Saccharomyces cerevisiae, GI6323882, Length=198, Percent_Identity=29.7979797979798, Blast_Score=69, Evalue=1e-12, Organism=Drosophila melanogaster, GI24639444, Length=248, Percent_Identity=35.8870967741936, Blast_Score=128, Evalue=4e-30, Organism=Drosophila melanogaster, GI28571526, Length=242, Percent_Identity=33.0578512396694, Blast_Score=111, Evalue=5e-25, Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=27.4193548387097, Blast_Score=110, Evalue=1e-24, Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=29.718875502008, Blast_Score=107, Evalue=9e-24, Organism=Drosophila melanogaster, GI21357041, Length=242, Percent_Identity=31.8181818181818, Blast_Score=103, Evalue=9e-23, Organism=Drosophila melanogaster, GI24644339, Length=246, Percent_Identity=30.4878048780488, Blast_Score=100, Evalue=7e-22, Organism=Drosophila melanogaster, GI24643142, Length=248, Percent_Identity=30.241935483871, Blast_Score=100, Evalue=8e-22, Organism=Drosophila melanogaster, GI24644337, Length=248, Percent_Identity=30.241935483871, Blast_Score=89, Evalue=4e-18, Organism=Drosophila melanogaster, GI24584744, Length=199, Percent_Identity=30.1507537688442, Blast_Score=88, Evalue=6e-18, Organism=Drosophila melanogaster, GI28574402, Length=199, Percent_Identity=30.1507537688442, Blast_Score=88, Evalue=6e-18, Organism=Drosophila melanogaster, GI24584748, Length=191, Percent_Identity=31.9371727748691, Blast_Score=85, Evalue=4e-17, Organism=Drosophila melanogaster, GI161076933, Length=191, Percent_Identity=31.9371727748691, Blast_Score=85, Evalue=4e-17, Organism=Drosophila melanogaster, GI21358495, Length=201, Percent_Identity=30.3482587064677, Blast_Score=84, Evalue=6e-17, Organism=Drosophila melanogaster, GI17737361, Length=255, Percent_Identity=28.2352941176471, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI24640442, Length=196, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI21357673, Length=193, Percent_Identity=29.5336787564767, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI18859837, Length=226, Percent_Identity=29.2035398230088, Blast_Score=77, Evalue=9e-15, Organism=Drosophila melanogaster, GI24640492, Length=178, Percent_Identity=27.5280898876405, Blast_Score=76, Evalue=3e-14, Organism=Drosophila melanogaster, GI24584752, Length=197, Percent_Identity=29.9492385786802, Blast_Score=75, Evalue=6e-14, Organism=Drosophila melanogaster, GI281364892, Length=172, Percent_Identity=31.3953488372093, Blast_Score=75, Evalue=6e-14, Organism=Drosophila melanogaster, GI21356301, Length=203, Percent_Identity=28.0788177339901, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24641232, Length=201, Percent_Identity=28.3582089552239, Blast_Score=72, Evalue=2e-13, Organism=Drosophila melanogaster, GI24581726, Length=199, Percent_Identity=30.1507537688442, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24665243, Length=209, Percent_Identity=26.3157894736842, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI221331218, Length=204, Percent_Identity=26.9607843137255, Blast_Score=64, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.69 [H]
Molecular weight: Translated: 27653; Mature: 27521
Theoretical pI: Translated: 6.63; Mature: 6.63
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTHALDRFRLDGRRALITGSGRGIGLTLARGLAEAGAAIVINDRNEEKAATLARQFRDEG CCCCCHHHEECCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCC FAADHAVFDVAEHAQVRAAIDDFETRVGAIDILVNNAGIQRRAPLDAFDPDDWHALMRVN CCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEC LDGVFNVAQAVARHMIARRHGKIINVCSVQSELARPTIAPYAATKGAVRMLTKGMCADWA CHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH RHGIQANGLAPGYFETELNRALVDDAAFSDWLCKRTPAGRWGQVDELCGAAIFLASAASD HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH FVNGQTLFVDGGLTSAV HCCCCEEEEECCHHCCC >Mature Secondary Structure THALDRFRLDGRRALITGSGRGIGLTLARGLAEAGAAIVINDRNEEKAATLARQFRDEG CCCCHHHEECCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCC FAADHAVFDVAEHAQVRAAIDDFETRVGAIDILVNNAGIQRRAPLDAFDPDDWHALMRVN CCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEC LDGVFNVAQAVARHMIARRHGKIINVCSVQSELARPTIAPYAATKGAVRMLTKGMCADWA CHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH RHGIQANGLAPGYFETELNRALVDDAAFSDWLCKRTPAGRWGQVDELCGAAIFLASAASD HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH FVNGQTLFVDGGLTSAV HCCCCEEEEECCHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7751271 [H]