BacMap

Definition	Burkholderia cenocepacia HI2424 chromosome 1, complete sequence.
Accession	NC_008542
Length	3,483,902

Click here to switch to the map view.

The map label for this gene is cpnA [H]

Identifier: 116688647

GI number: 116688647

Start: 696210

End: 697025

Strand: Direct

Name: cpnA [H]

Synonym: Bcen2424_0624

Alternate gene names: 116688647

Gene position: 696210-697025 (Clockwise)

Preceding gene: 116688646

Following gene: 116688648

Centisome position: 19.98

GC content: 70.22

Gene sequence:

>816_bases
ATGACCATCGATACTTCCGCGCCTGACTCGCAGGCTACGCACGCCGCGAGCGACGCGCGTTTCGCGCGCTACCCGAGCCT
CGAGGATCGCGCGGTGCTGATCACGGGCGGCGCGACCGGCATCGGCGCGTCGTTCGTCGAGCACTTCGCCGAACAGGGCG
CGCGCGTCGCGTTCGTCGACCTCGATGCGGCGGCCGGCGCCGCGCTCGCGGAACGCCTCGCGCACGTACGCCATGCGCCG
CTGTTTCTCTCGTGCGACCTGACCGACATCGATGCGCTGCGCCATGCGATCGATGCGATCCGCGCGCGCATCGGCGCGAT
CGCGGTACTCGTGAACAACGCGGCGAACGACGCGCGCCACGCGATCGGCGACGTGACGCCCGCGTCGTTCGACGCGGGCA
TCGCGGTGAACCTGCGTCACCAGTTCTTTGCCGCGCAGGCGGTGATCGACGACATGAAACGGCAGGGCGGCGGCGCGATC
ATCAATCTCGGCTCGATCAGCTGGATGCTGAAGAACGGCGGCTATCCGGTCTACGTGATGGCGAAGGCGGCCGTGCAGGG
CCTGACGCGCGGCCTCGCGCGCGATCTCGGCCCGTTCGGCATCCGCGTGAATTCGCTGGTGCCCGGCTGGGTGATGACCG
ACAAGCAGCGCCGGCTGTGGCTCGACGACGCGGGCCGCGCGGCGATCAAGGCCGGCCAGTGCCTCGACGCCGAACTGCTG
CCGGCCGACCTCGCGCGGATGGCGCTGTTTCTCGCGGCCGACGACAGCCGGATGATCACCGCGCAGGACGTGATCGTCGA
CGGCGGCTGGGCCTGA

Upstream 100 bases:

>100_bases
CTGGTGCGTGGCGCGATCCTGCTCGCGGCCGTGCTGCTCGACCAGCTGAAGAACCGCGGCGTACGCGACTGACCGACCTG
TTTCCACGGAGACGACCTGC

Downstream 100 bases:

>100_bases
CCGCTCGCACGACCTGCATCGTTTCTTCGACGAAGGAAAGGAGCTCACCATGACGGCCACGTCCTCGCGCGCATCGTCGT
CCACCAGCCAGTCGCGCCGC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MTIDTSAPDSQATHAASDARFARYPSLEDRAVLITGGATGIGASFVEHFAEQGARVAFVDLDAAAGAALAERLAHVRHAP
LFLSCDLTDIDALRHAIDAIRARIGAIAVLVNNAANDARHAIGDVTPASFDAGIAVNLRHQFFAAQAVIDDMKRQGGGAI
INLGSISWMLKNGGYPVYVMAKAAVQGLTRGLARDLGPFGIRVNSLVPGWVMTDKQRRLWLDDAGRAAIKAGQCLDAELL
PADLARMALFLAADDSRMITAQDVIVDGGWA

Sequences:

>Translated_271_residues
MTIDTSAPDSQATHAASDARFARYPSLEDRAVLITGGATGIGASFVEHFAEQGARVAFVDLDAAAGAALAERLAHVRHAP
LFLSCDLTDIDALRHAIDAIRARIGAIAVLVNNAANDARHAIGDVTPASFDAGIAVNLRHQFFAAQAVIDDMKRQGGGAI
INLGSISWMLKNGGYPVYVMAKAAVQGLTRGLARDLGPFGIRVNSLVPGWVMTDKQRRLWLDDAGRAAIKAGQCLDAELL
PADLARMALFLAADDSRMITAQDVIVDGGWA
>Mature_270_residues
TIDTSAPDSQATHAASDARFARYPSLEDRAVLITGGATGIGASFVEHFAEQGARVAFVDLDAAAGAALAERLAHVRHAPL
FLSCDLTDIDALRHAIDAIRARIGAIAVLVNNAANDARHAIGDVTPASFDAGIAVNLRHQFFAAQAVIDDMKRQGGGAII
NLGSISWMLKNGGYPVYVMAKAAVQGLTRGLARDLGPFGIRVNSLVPGWVMTDKQRRLWLDDAGRAAIKAGQCLDAELLP
ADLARMALFLAADDSRMITAQDVIVDGGWA

Specific function: Reduces cyclopentanol to cyclopentanone. The enzyme also shows considerable activity toward cyclohexanol [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=261, Percent_Identity=29.8850574712644, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI15277342, Length=250, Percent_Identity=32.8, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI31542939, Length=193, Percent_Identity=32.6424870466321, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI7705925, Length=253, Percent_Identity=32.8063241106719, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI59889578, Length=233, Percent_Identity=29.6137339055794, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI19923817, Length=254, Percent_Identity=25.9842519685039, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=27.0491803278689, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI126723750, Length=268, Percent_Identity=24.6268656716418, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI10190704, Length=248, Percent_Identity=29.8387096774194, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI66933014, Length=232, Percent_Identity=29.3103448275862, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI224922801, Length=171, Percent_Identity=31.5789473684211, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI4758504, Length=205, Percent_Identity=29.7560975609756, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI126723191, Length=225, Percent_Identity=27.1111111111111, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI1787335, Length=247, Percent_Identity=30.7692307692308, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1790717, Length=244, Percent_Identity=29.9180327868852, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1789208, Length=246, Percent_Identity=29.6747967479675, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI87082100, Length=251, Percent_Identity=28.6852589641434, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=28.9156626506024, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI87082160, Length=256, Percent_Identity=29.296875, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1786812, Length=248, Percent_Identity=29.0322580645161, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI2367365, Length=242, Percent_Identity=30.1652892561983, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1789378, Length=253, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1788891, Length=194, Percent_Identity=31.9587628865979, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789057, Length=255, Percent_Identity=29.8039215686275, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI2367175, Length=188, Percent_Identity=28.1914893617021, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=27.6679841897233, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=30.8943089430894, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=30, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI72000259, Length=266, Percent_Identity=29.3233082706767, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=255, Percent_Identity=28.6274509803922, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=272, Percent_Identity=29.4117647058824, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=27.6422764227642, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=277, Percent_Identity=28.5198555956679, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=271, Percent_Identity=27.3062730627306, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=246, Percent_Identity=26.8292682926829, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=28.1368821292776, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=269, Percent_Identity=28.6245353159851, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=268, Percent_Identity=29.8507462686567, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17567345, Length=190, Percent_Identity=26.3157894736842, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=271, Percent_Identity=29.1512915129151, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=244, Percent_Identity=25.4098360655738, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=254, Percent_Identity=25.1968503937008, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=26.9961977186312, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=277, Percent_Identity=26.7148014440433, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=263, Percent_Identity=26.2357414448669, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=273, Percent_Identity=27.8388278388278, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=276, Percent_Identity=27.8985507246377, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=273, Percent_Identity=27.1062271062271, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508651, Length=245, Percent_Identity=26.1224489795918, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=270, Percent_Identity=26.6666666666667, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=201, Percent_Identity=27.363184079602, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=30, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=29.6, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI23397609, Length=198, Percent_Identity=31.3131313131313, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=29.5546558704453, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24644337, Length=245, Percent_Identity=30.6122448979592, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281364892, Length=182, Percent_Identity=31.3186813186813, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24639444, Length=256, Percent_Identity=27.734375, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21355319, Length=263, Percent_Identity=25.8555133079848, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24644339, Length=246, Percent_Identity=26.8292682926829, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.163 [H]

Molecular weight: Translated: 28581; Mature: 28450

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIDTSAPDSQATHAASDARFARYPSLEDRAVLITGGATGIGASFVEHFAEQGARVAFVD
CCCCCCCCCCHHHHHHCCCHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEE
LDAAAGAALAERLAHVRHAPLFLSCDLTDIDALRHAIDAIRARIGAIAVLVNNAANDARH
CCHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHEEEEEEECCCCHHHH
AIGDVTPASFDAGIAVNLRHQFFAAQAVIDDMKRQGGGAIINLGSISWMLKNGGYPVYVM
HHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEEECCCCEEEEE
AKAAVQGLTRGLARDLGPFGIRVNSLVPGWVMTDKQRRLWLDDAGRAAIKAGQCLDAELL
HHHHHHHHHHHHHHCCCCCCEEECCCCCCCEEECCCCEEEECCCCCHHHHCCCCCCCCCC
PADLARMALFLAADDSRMITAQDVIVDGGWA
HHHHHHHEEEEECCCCCEEEEEEEEECCCCC
>Mature Secondary Structure 
TIDTSAPDSQATHAASDARFARYPSLEDRAVLITGGATGIGASFVEHFAEQGARVAFVD
CCCCCCCCCHHHHHHCCCHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEE
LDAAAGAALAERLAHVRHAPLFLSCDLTDIDALRHAIDAIRARIGAIAVLVNNAANDARH
CCHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHEEEEEEECCCCHHHH
AIGDVTPASFDAGIAVNLRHQFFAAQAVIDDMKRQGGGAIINLGSISWMLKNGGYPVYVM
HHCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEEECCCCEEEEE
AKAAVQGLTRGLARDLGPFGIRVNSLVPGWVMTDKQRRLWLDDAGRAAIKAGQCLDAELL
HHHHHHHHHHHHHHCCCCCCEEECCCCCCCEEECCCCEEEECCCCCHHHHCCCCCCCCCC
PADLARMALFLAADDSRMITAQDVIVDGGWA
HHHHHHHEEEEECCCCCEEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12406764 [H]