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The map label for this gene is pilC [H]

Identifier: 116688601

GI number: 116688601

Start: 648400

End: 649611

Strand: Reverse

Name: pilC [H]

Synonym: Bcen2424_0577

Alternate gene names: 116688601

Gene position: 649611-648400 (Counterclockwise)

Preceding gene: 116688602

Following gene: 116688600

Centisome position: 18.65

GC content: 73.02

Gene sequence:

>1212_bases
ATGAGCATGCGCACGCCACCGCGCGAAACCCGCTTTGCATGGCGCGGCCGCCGTCGCGACGGCTCGCCCCGCCGCGGGAC
CGTCATCGCCTTCGACGCCGCGGCCGCGCGCGCCACGCTCGCGCGCGAAGGCATTGCGGTACTGTCGCTCGACGTTCGCG
GGCCGGCCCGTCCGCCTGCGGCGGCCGCGCGCGACATCACACGCTTCACGCGCCAGCTCGCGAGCCTGCTGCAGGCCGGC
CTGCCGCTCGCGCCGTCGCTCGAGATGCTCGCGCGCACCCGCACGCGCGACGGCGTGCCCCGCATCGCCGCGGGGCTCGC
CCGCGAGATCGTCGGCGGCCGGCGCTTCGCCGATGCACTCGCACGCTATCCATCGCAATTCGGCACGCTGTATCGCCAGT
TGATCGAGGTCGGCGAGGCGTCCGGTTCGCTCGGCATCGTACTGACGCGGGTTGCGGAACACCGCGAGCGCGCCGATGCG
CAATGGCGCAAGCTGCGTGCCGCGCTCGCGTATCCGGCCGCCGTCATCCTGTTCGCACTCGCGATCTCGGCGGCATTGAT
GGTGTGGGTCGTGCCGACCTTCCGGCAGATCTTCGACGGCTTCGGCGCCGCCCTGCCCGCGCCGACCCGCGCACTGCTCG
CGCTGTCCTCCGCGCTGTCGGCATGGGGCGGCGTGTTCCTGGCCGGTGCGGCCGCCACGGGGCTTGCCGCACAGCACGCG
CTTCGGCGCTCGGCCGCGCTACGCCATGTGCTAGCGCGGCGCCTGCTGCGCGCGCCGCTCGCGGGCAGCGCGCTGGAACG
GTTCGCGGCCGCACGCTGGTGCCGGTCGCTGGCGACCCTGCTCGGCGCCGGCGTGCCGCTCGCCGATGCGTTCGCCACGC
TCGAGCGCACCGCCGGCCATCCGGTGTTCGCGCACGCCACCGCGCACATCGCCGCACGCGTGCTGCGCGGCGTGCGTCTG
GCCGATGCGATGCATTCGGCCGGCTGCTTTCCGGACGACGTCGTGCAACCGATCGCCGTCGCCGAGGAAACCGGTGCGCT
CGACACGATGCTCGCCGACATCGCCGCATTGTGCGAACGCCAGCTCGACGCGCGTCTCGATACGCTCGCGGCGCTGGGTG
AACCGTTGATCGTGATCGTCCTGGGCGCACTCGTCGGCGGCCTTGTGATCGCGATGTACCTGCCGATCCTTCAGCTCGGC
AACGTGGTGTAG

Upstream 100 bases:

>100_bases
TGGCGGCCGAGGGCGTGCGCAGCCTGCGCGACGCGGCATTCGCGCGCGTCCTGGACGGCACGACGAGCATCGCGGAAGCC
GTCGCCGCCACACCTGCGGC

Downstream 100 bases:

>100_bases
CATCGCAACCGATTCTGTCGCCTTTTAGTCCAACCTCGAGCCTCATGACGCCAGTGCCCCTGTCCACCGTTTCCGATTCG
CCCGAGGGCACGCTGCTCGC

Product: type II secretion system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MSMRTPPRETRFAWRGRRRDGSPRRGTVIAFDAAAARATLAREGIAVLSLDVRGPARPPAAAARDITRFTRQLASLLQAG
LPLAPSLEMLARTRTRDGVPRIAAGLAREIVGGRRFADALARYPSQFGTLYRQLIEVGEASGSLGIVLTRVAEHRERADA
QWRKLRAALAYPAAVILFALAISAALMVWVVPTFRQIFDGFGAALPAPTRALLALSSALSAWGGVFLAGAAATGLAAQHA
LRRSAALRHVLARRLLRAPLAGSALERFAAARWCRSLATLLGAGVPLADAFATLERTAGHPVFAHATAHIAARVLRGVRL
ADAMHSAGCFPDDVVQPIAVAEETGALDTMLADIAALCERQLDARLDTLAALGEPLIVIVLGALVGGLVIAMYLPILQLG
NVV

Sequences:

>Translated_403_residues
MSMRTPPRETRFAWRGRRRDGSPRRGTVIAFDAAAARATLAREGIAVLSLDVRGPARPPAAAARDITRFTRQLASLLQAG
LPLAPSLEMLARTRTRDGVPRIAAGLAREIVGGRRFADALARYPSQFGTLYRQLIEVGEASGSLGIVLTRVAEHRERADA
QWRKLRAALAYPAAVILFALAISAALMVWVVPTFRQIFDGFGAALPAPTRALLALSSALSAWGGVFLAGAAATGLAAQHA
LRRSAALRHVLARRLLRAPLAGSALERFAAARWCRSLATLLGAGVPLADAFATLERTAGHPVFAHATAHIAARVLRGVRL
ADAMHSAGCFPDDVVQPIAVAEETGALDTMLADIAALCERQLDARLDTLAALGEPLIVIVLGALVGGLVIAMYLPILQLG
NVV
>Mature_402_residues
SMRTPPRETRFAWRGRRRDGSPRRGTVIAFDAAAARATLAREGIAVLSLDVRGPARPPAAAARDITRFTRQLASLLQAGL
PLAPSLEMLARTRTRDGVPRIAAGLAREIVGGRRFADALARYPSQFGTLYRQLIEVGEASGSLGIVLTRVAEHRERADAQ
WRKLRAALAYPAAVILFALAISAALMVWVVPTFRQIFDGFGAALPAPTRALLALSSALSAWGGVFLAGAAATGLAAQHAL
RRSAALRHVLARRLLRAPLAGSALERFAAARWCRSLATLLGAGVPLADAFATLERTAGHPVFAHATAHIAARVLRGVRLA
DAMHSAGCFPDDVVQPIAVAEETGALDTMLADIAALCERQLDARLDTLAALGEPLIVIVLGALVGGLVIAMYLPILQLGN
VV

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=399, Percent_Identity=28.8220551378446, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1786295, Length=388, Percent_Identity=27.5773195876289, Blast_Score=124, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 42623; Mature: 42492

Theoretical pI: Translated: 11.88; Mature: 11.88

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMRTPPRETRFAWRGRRRDGSPRRGTVIAFDAAAARATLAREGIAVLSLDVRGPARPPA
CCCCCCCHHHHHHHCCCCCCCCCCCCEEEEECHHHHHHHHHHCCCEEEEEECCCCCCCCH
AAARDITRFTRQLASLLQAGLPLAPSLEMLARTRTRDGVPRIAAGLAREIVGGRRFADAL
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHH
ARYPSQFGTLYRQLIEVGEASGSLGIVLTRVAEHRERADAQWRKLRAALAYPAAVILFAL
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AISAALMVWVVPTFRQIFDGFGAALPAPTRALLALSSALSAWGGVFLAGAAATGLAAQHA
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRRSAALRHVLARRLLRAPLAGSALERFAAARWCRSLATLLGAGVPLADAFATLERTAGH
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
PVFAHATAHIAARVLRGVRLADAMHSAGCFPDDVVQPIAVAEETGALDTMLADIAALCER
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLDARLDTLAALGEPLIVIVLGALVGGLVIAMYLPILQLGNVV
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SMRTPPRETRFAWRGRRRDGSPRRGTVIAFDAAAARATLAREGIAVLSLDVRGPARPPA
CCCCCCHHHHHHHCCCCCCCCCCCCEEEEECHHHHHHHHHHCCCEEEEEECCCCCCCCH
AAARDITRFTRQLASLLQAGLPLAPSLEMLARTRTRDGVPRIAAGLAREIVGGRRFADAL
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHH
ARYPSQFGTLYRQLIEVGEASGSLGIVLTRVAEHRERADAQWRKLRAALAYPAAVILFAL
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AISAALMVWVVPTFRQIFDGFGAALPAPTRALLALSSALSAWGGVFLAGAAATGLAAQHA
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRRSAALRHVLARRLLRAPLAGSALERFAAARWCRSLATLLGAGVPLADAFATLERTAGH
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
PVFAHATAHIAARVLRGVRLADAMHSAGCFPDDVVQPIAVAEETGALDTMLADIAALCER
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLDARLDTLAALGEPLIVIVLGALVGGLVIAMYLPILQLGNVV
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]