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The map label for this gene is rocA [H]

Identifier: 116688567

GI number: 116688567

Start: 603251

End: 604957

Strand: Reverse

Name: rocA [H]

Synonym: Bcen2424_0543

Alternate gene names: 116688567

Gene position: 604957-603251 (Counterclockwise)

Preceding gene: 116688572

Following gene: 116688566

Centisome position: 17.36

GC content: 67.31

Gene sequence:

>1707_bases
ATGACCCACGCACTGTTCACGAAGCACGAAGACACGCTGAAACACGCACTCGCCGCCATCGAGAGCCGCGGGTACTGGAG
CCCGTTCGCCGAAATGCCGAGCCCCAAAGTGTACGGGGAAAGCGCCAGCGCGGACGGTGAGGCCGCGTTCAAGTCACACC
TCGACAAGACCTTCGTGCTCGACCAGCCGGCGACCGGTGAAACGGTCGGCGCCGAGCGCTCGCCGTACGGCATCGCGCTG
GGCGTCCGGTACCCGAAATCGGCGCCCGACGCACTGATCGCTGCTGCCGCCGCCGCGCAACGCACGTGGCGCGAAGCCGG
CCCGAGCGCATGGGTCGGCGTCAGCCTCGAAATCCTCGCGCGCCTGAACCGTGCAAGCTTCGAAATTGCCTACAGCGTGA
TGCACACCACCGGGCAAGCCTTCATGATGGCGTTTCAGGCCGGCGGCCCGCACGCGCAGGACCGCGCCCTCGAGGCGGTC
GCCTATGCGTGGGACGAACTGCGCCGCATCCCGGCCGATGCGCACTGGGAAAAACCGCAAGGCAAGAACCCGCCGCTCGC
GATGCACAAGCGCTACACGATCGTGCCGCGCGGCACGGGCCTCGTGCTCGGCTGCTGCACGTTCCCGACCTGGAACGGCT
ACCCGGGCCTGTTCGCCGACCTGGCAACCGGTAATACCGTGATCGTCAAACCGCACCCCGGCGCGATCCTGCCGCTCGCC
ATCACGGTGCGGATCGCCCGCGACGTGCTGCGCGAAGCCGGGTTCGATCCGAACGTCGTCACGCTCCTCGCGACCGAACC
CAACGACGGCGCCCTCGTCCAGGACCTCGCGCTGCGCCCCGAGATCAAGCTGATCGACTTCACCGGCAGCACGCAGAACG
GCACGTGGCTCGAACGCCATGCCCACCAGGCACAGGTCTATACCGAGAAAGCCGGCGTCAACCAGATCGTGATCGACTCG
ACCGACGACCTGAAGGCCGCCGCCAAGAACATCGCGTTCTCGCTGGCGCTGTACTCCGGCCAGATGTGCACGGCACCGCA
GAACATCTACGTGCCACGCGGCGGCATCCGGACGACCGACGGCCATGCGAGCTTCGACGAAGTCGCGCAGGCGATCGCGG
TTGCCGTGCAAAAACTCACCGGCGATCCAGCTCGCTCGGTCGAACTGATCGGTGCGATCCAGAATGAAGGCGTGACTGCG
CGCATCGACGACGCGCGCAAGCTCGGCCGCGTACTCGCGGACAGCGTGACGCTCCAGCATCCCGCCTTCCCCGATGCGCG
CGTGCGTACGCCGCTCGTGCTGCAACTCGACGTGGCCGACCGAGAGAAATTCACCCAGGAGTGGTTCGGCCCGATCTCGT
TCGTGATCGCGACCGACTCGACCGCGCAGTCGCTCGATCTCGCCGGTGAAATCGCAGCCGAGCATGGCGCACTGACCCTC
TCCGTCTACAGCACGGACGACGCAATCGTCGACGCCGCACACGACGCGGCAGTGCGTGGCGGCGTCGCGCTGTCGATCAA
CCTCACGGGCGGCGTATTCGTCAACCAGTCGGCCGCGTTCTCCGACTTCCACGGCACGGGCGCGAACCCGGCAGCCAACG
CAGCGCTGGCCGACCCGGCATTCGTCGCCAACCGGTTCCGCGTGGTGCAAAGCCGCGTCCATGTTGCCCCGAAGGCGGCA
CCCGCGGAAGCTGGCCAGACGGCATAA

Upstream 100 bases:

>100_bases
ACGCCTCGCACATGCGAATAGTTTGATGCTACCATTCTCCGACCAACCGGTCGGTTAATTAATCGATCCAATCCCTCTCA
ACGTTCATCAGGCCGCCGCC

Downstream 100 bases:

>100_bases
CCCGATTGACCGACGTGCAAACGCCACTACGTTCTCTACCATGAACGAATCCGCCACCCGGCAGGTTCGTCACTCACCGA
TACGCTCATGACAGACGCCT

Product: phenylacetic acid degradation protein paaN

Products: NA

Alternate protein names: P5C dehydrogenase [H]

Number of amino acids: Translated: 568; Mature: 567

Protein sequence:

>568_residues
MTHALFTKHEDTLKHALAAIESRGYWSPFAEMPSPKVYGESASADGEAAFKSHLDKTFVLDQPATGETVGAERSPYGIAL
GVRYPKSAPDALIAAAAAAQRTWREAGPSAWVGVSLEILARLNRASFEIAYSVMHTTGQAFMMAFQAGGPHAQDRALEAV
AYAWDELRRIPADAHWEKPQGKNPPLAMHKRYTIVPRGTGLVLGCCTFPTWNGYPGLFADLATGNTVIVKPHPGAILPLA
ITVRIARDVLREAGFDPNVVTLLATEPNDGALVQDLALRPEIKLIDFTGSTQNGTWLERHAHQAQVYTEKAGVNQIVIDS
TDDLKAAAKNIAFSLALYSGQMCTAPQNIYVPRGGIRTTDGHASFDEVAQAIAVAVQKLTGDPARSVELIGAIQNEGVTA
RIDDARKLGRVLADSVTLQHPAFPDARVRTPLVLQLDVADREKFTQEWFGPISFVIATDSTAQSLDLAGEIAAEHGALTL
SVYSTDDAIVDAAHDAAVRGGVALSINLTGGVFVNQSAAFSDFHGTGANPAANAALADPAFVANRFRVVQSRVHVAPKAA
PAEAGQTA

Sequences:

>Translated_568_residues
MTHALFTKHEDTLKHALAAIESRGYWSPFAEMPSPKVYGESASADGEAAFKSHLDKTFVLDQPATGETVGAERSPYGIAL
GVRYPKSAPDALIAAAAAAQRTWREAGPSAWVGVSLEILARLNRASFEIAYSVMHTTGQAFMMAFQAGGPHAQDRALEAV
AYAWDELRRIPADAHWEKPQGKNPPLAMHKRYTIVPRGTGLVLGCCTFPTWNGYPGLFADLATGNTVIVKPHPGAILPLA
ITVRIARDVLREAGFDPNVVTLLATEPNDGALVQDLALRPEIKLIDFTGSTQNGTWLERHAHQAQVYTEKAGVNQIVIDS
TDDLKAAAKNIAFSLALYSGQMCTAPQNIYVPRGGIRTTDGHASFDEVAQAIAVAVQKLTGDPARSVELIGAIQNEGVTA
RIDDARKLGRVLADSVTLQHPAFPDARVRTPLVLQLDVADREKFTQEWFGPISFVIATDSTAQSLDLAGEIAAEHGALTL
SVYSTDDAIVDAAHDAAVRGGVALSINLTGGVFVNQSAAFSDFHGTGANPAANAALADPAFVANRFRVVQSRVHVAPKAA
PAEAGQTA
>Mature_567_residues
THALFTKHEDTLKHALAAIESRGYWSPFAEMPSPKVYGESASADGEAAFKSHLDKTFVLDQPATGETVGAERSPYGIALG
VRYPKSAPDALIAAAAAAQRTWREAGPSAWVGVSLEILARLNRASFEIAYSVMHTTGQAFMMAFQAGGPHAQDRALEAVA
YAWDELRRIPADAHWEKPQGKNPPLAMHKRYTIVPRGTGLVLGCCTFPTWNGYPGLFADLATGNTVIVKPHPGAILPLAI
TVRIARDVLREAGFDPNVVTLLATEPNDGALVQDLALRPEIKLIDFTGSTQNGTWLERHAHQAQVYTEKAGVNQIVIDST
DDLKAAAKNIAFSLALYSGQMCTAPQNIYVPRGGIRTTDGHASFDEVAQAIAVAVQKLTGDPARSVELIGAIQNEGVTAR
IDDARKLGRVLADSVTLQHPAFPDARVRTPLVLQLDVADREKFTQEWFGPISFVIATDSTAQSLDLAGEIAAEHGALTLS
VYSTDDAIVDAAHDAAVRGGVALSINLTGGVFVNQSAAFSDFHGTGANPAANAALADPAFVANRFRVVQSRVHVAPKAAP
AEAGQTA

Specific function: Oxidizes Proline To Glutamate For Use As A Carbon And Nitrogen Source And Also Function As A Transcriptional Repressor Of The Put Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family. RocA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787684, Length=276, Percent_Identity=25, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17564084, Length=421, Percent_Identity=22.8028503562945, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321828, Length=342, Percent_Identity=25.7309941520468, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320917, Length=192, Percent_Identity=32.8125, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323822, Length=341, Percent_Identity=27.8592375366569, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323821, Length=341, Percent_Identity=26.6862170087977, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005932 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.5.1.12 [H]

Molecular weight: Translated: 60400; Mature: 60268

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHALFTKHEDTLKHALAAIESRGYWSPFAEMPSPKVYGESASADGEAAFKSHLDKTFVL
CCCCEECCCHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHCCCCEEEE
DQPATGETVGAERSPYGIALGVRYPKSAPDALIAAAAAAQRTWREAGPSAWVGVSLEILA
CCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEECHHHHHHH
RLNRASFEIAYSVMHTTGQAFMMAFQAGGPHAQDRALEAVAYAWDELRRIPADAHWEKPQ
HHCCCHHHEEHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GKNPPLAMHKRYTIVPRGTGLVLGCCTFPTWNGYPGLFADLATGNTVIVKPHPGAILPLA
CCCCCEEECCEEEEEECCCCEEEEEECCCCCCCCCCHHEECCCCCEEEECCCCCCEEHHH
ITVRIARDVLREAGFDPNVVTLLATEPNDGALVQDLALRPEIKLIDFTGSTQNGTWLERH
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHCCCCEEEEEECCCCCCCCHHHHH
AHQAQVYTEKAGVNQIVIDSTDDLKAAAKNIAFSLALYSGQMCTAPQNIYVPRGGIRTTD
HHHHHEEHHHCCCCEEEEECCHHHHHHHHHHEEEEEEECCCEECCCCEEEECCCCCCCCC
GHASFDEVAQAIAVAVQKLTGDPARSVELIGAIQNEGVTARIDDARKLGRVLADSVTLQH
CCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHCEEECC
PAFPDARVRTPLVLQLDVADREKFTQEWFGPISFVIATDSTAQSLDLAGEIAAEHGALTL
CCCCCCCCCCCEEEEEECCCHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEE
SVYSTDDAIVDAAHDAAVRGGVALSINLTGGVFVNQSAAFSDFHGTGANPAANAALADPA
EEEECCCHHHCCHHHHHHCCCEEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCHH
FVANRFRVVQSRVHVAPKAAPAEAGQTA
HHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
THALFTKHEDTLKHALAAIESRGYWSPFAEMPSPKVYGESASADGEAAFKSHLDKTFVL
CCCEECCCHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHCCCCEEEE
DQPATGETVGAERSPYGIALGVRYPKSAPDALIAAAAAAQRTWREAGPSAWVGVSLEILA
CCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEECHHHHHHH
RLNRASFEIAYSVMHTTGQAFMMAFQAGGPHAQDRALEAVAYAWDELRRIPADAHWEKPQ
HHCCCHHHEEHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GKNPPLAMHKRYTIVPRGTGLVLGCCTFPTWNGYPGLFADLATGNTVIVKPHPGAILPLA
CCCCCEEECCEEEEEECCCCEEEEEECCCCCCCCCCHHEECCCCCEEEECCCCCCEEHHH
ITVRIARDVLREAGFDPNVVTLLATEPNDGALVQDLALRPEIKLIDFTGSTQNGTWLERH
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHCCCCEEEEEECCCCCCCCHHHHH
AHQAQVYTEKAGVNQIVIDSTDDLKAAAKNIAFSLALYSGQMCTAPQNIYVPRGGIRTTD
HHHHHEEHHHCCCCEEEEECCHHHHHHHHHHEEEEEEECCCEECCCCEEEECCCCCCCCC
GHASFDEVAQAIAVAVQKLTGDPARSVELIGAIQNEGVTARIDDARKLGRVLADSVTLQH
CCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHCEEECC
PAFPDARVRTPLVLQLDVADREKFTQEWFGPISFVIATDSTAQSLDLAGEIAAEHGALTL
CCCCCCCCCCCEEEEEECCCHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEE
SVYSTDDAIVDAAHDAAVRGGVALSINLTGGVFVNQSAAFSDFHGTGANPAANAALADPA
EEEECCCHHHCCHHHHHHCCCEEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCHH
FVANRFRVVQSRVHVAPKAAPAEAGQTA
HHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA