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The map label for this gene is hitA [H]

Identifier: 116688459

GI number: 116688459

Start: 482464

End: 482829

Strand: Direct

Name: hitA [H]

Synonym: Bcen2424_0435

Alternate gene names: 116688459

Gene position: 482464-482829 (Clockwise)

Preceding gene: 116688458

Following gene: 116688460

Centisome position: 13.85

GC content: 68.31

Gene sequence:

>366_bases
ATGAGTCACGATCCGAATTGCCTGTTCTGCAAGATCGCTGCAGGCGAGATCCCGAGCACGAAGGTGCACGAGGACGACGA
ATTCGTCGCGTTCCGCGACATCCGCCCGGCGGCCGACACGCACGTGCTCGTGATTCCGCGCCGGCACCTGCCGACGCTGT
CGGCGGCGAGCGAGGCCGATGCGCCGATGCTCGGCCGGCTGATGCTGCTCGTCGCACGTCTGGCCGATCAGCTCGGCGTC
GCGTATACGGGCGGCGAAACCGGTTTTCGCACGGTGATCAACACGGGCCCGGGCGGCGGGCAGGAGGTCTACCACCTGCA
CGCGCATATCCTGGCCGGCCCGCGCCCGTGGCAGCGGATGGGTTGA

Upstream 100 bases:

>100_bases
TACCGTATCATCAAGGGTTGGCTGTACCTGAACGACAACAAGACGCTCGATCCGCAGGCGTGGTTCTGACCGGCGCGCGC
GGGCGTTTCGCAGGAGCAAC

Downstream 100 bases:

>100_bases
CGCAGCGGGGCGTTTCCCCGCATCGATAGTCGAAGCCGGCGCGTCGCCGGCGATTTACGCCGCCCCGCGGCGTGGTTGAG
GAGAGGTTTCATCATGGGTG

Product: histidine triad (HIT) protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 121; Mature: 120

Protein sequence:

>121_residues
MSHDPNCLFCKIAAGEIPSTKVHEDDEFVAFRDIRPAADTHVLVIPRRHLPTLSAASEADAPMLGRLMLLVARLADQLGV
AYTGGETGFRTVINTGPGGGQEVYHLHAHILAGPRPWQRMG

Sequences:

>Translated_121_residues
MSHDPNCLFCKIAAGEIPSTKVHEDDEFVAFRDIRPAADTHVLVIPRRHLPTLSAASEADAPMLGRLMLLVARLADQLGV
AYTGGETGFRTVINTGPGGGQEVYHLHAHILAGPRPWQRMG
>Mature_120_residues
SHDPNCLFCKIAAGEIPSTKVHEDDEFVAFRDIRPAADTHVLVIPRRHLPTLSAASEADAPMLGRLMLLVARLADQLGVA
YTGGETGFRTVINTGPGGGQEVYHLHAHILAGPRPWQRMG

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI4885413, Length=108, Percent_Identity=43.5185185185185, Blast_Score=97, Evalue=3e-21,
Organism=Homo sapiens, GI14211923, Length=107, Percent_Identity=39.2523364485981, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1787346, Length=112, Percent_Identity=45.5357142857143, Blast_Score=87, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17506713, Length=108, Percent_Identity=44.4444444444444, Blast_Score=101, Evalue=7e-23,
Organism=Drosophila melanogaster, GI28574010, Length=108, Percent_Identity=49.0740740740741, Blast_Score=102, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24581222, Length=108, Percent_Identity=49.0740740740741, Blast_Score=102, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 13105; Mature: 12974

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHDPNCLFCKIAAGEIPSTKVHEDDEFVAFRDIRPAADTHVLVIPRRHLPTLSAASEAD
CCCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCC
APMLGRLMLLVARLADQLGVAYTGGETGFRTVINTGPGGGQEVYHLHAHILAGPRPWQRM
CCHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEECCCCCCCEEEEEEEEEECCCCCCCCC
G
C
>Mature Secondary Structure 
SHDPNCLFCKIAAGEIPSTKVHEDDEFVAFRDIRPAADTHVLVIPRRHLPTLSAASEAD
CCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCC
APMLGRLMLLVARLADQLGVAYTGGETGFRTVINTGPGGGQEVYHLHAHILAGPRPWQRM
CCHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEECCCCCCCEEEEEEEEEECCCCCCCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA