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The map label for this gene is hisE [H]

Identifier: 116688457

GI number: 116688457

Start: 481604

End: 481969

Strand: Direct

Name: hisE [H]

Synonym: Bcen2424_0433

Alternate gene names: 116688457

Gene position: 481604-481969 (Clockwise)

Preceding gene: 116688456

Following gene: 116688458

Centisome position: 13.82

GC content: 67.21

Gene sequence:

>366_bases
ATGACGCAATCGACCGAAGACACGCTGCTGCGCCTCGCGGCCGTGATCGACAGCCGCAAGGGCGGCGATCCCGATCAATC
GTACGTATCGCGCCTGTTCCACAAGGGCGACGACGCGGTGCTGAAGAAGATCGGCGAAGAGGCGACGGAAGTCGTGCTGG
CCGCGAAGGACGTGCGCCAGGGCGGCGCGCCGAGCGCGCTGGTCGGCGAGGTGGCCGACCTGTGGTTCCACTGCCTCGTG
ATGCTGTCGCATTTCGACCTGAGCCCGGCCGACGTGATCGCCGAGCTCGAGCGTCGCGAAGGCTTGTCGGGCATCGAGGA
AAAAGCGCTGCGCAAGCGCCGCGAGCGCGAGGAAAACGGCGGGTGA

Upstream 100 bases:

>100_bases
GCCGGCATTCGTGCTTCTTCCAGAAATTCGAAGGTACGGTGGACGGCGGCGACTGGGTCGCGGTCGAGCCGGTGCTGAAA
GACCCCGAACACATCTACAA

Downstream 100 bases:

>100_bases
CACGCAGACCCCGCCGCGGTGGCAACAGTGGGGTAAGCTGTAAGAATTGTCATCTAACGGGGGTAGCATCATGAACGATA
CGTCGAACCAGTTCCCGACG

Product: phosphoribosyl-ATP pyrophosphatase

Products: NA

Alternate protein names: PRA-PH [H]

Number of amino acids: Translated: 121; Mature: 120

Protein sequence:

>121_residues
MTQSTEDTLLRLAAVIDSRKGGDPDQSYVSRLFHKGDDAVLKKIGEEATEVVLAAKDVRQGGAPSALVGEVADLWFHCLV
MLSHFDLSPADVIAELERREGLSGIEEKALRKRREREENGG

Sequences:

>Translated_121_residues
MTQSTEDTLLRLAAVIDSRKGGDPDQSYVSRLFHKGDDAVLKKIGEEATEVVLAAKDVRQGGAPSALVGEVADLWFHCLV
MLSHFDLSPADVIAELERREGLSGIEEKALRKRREREENGG
>Mature_120_residues
TQSTEDTLLRLAAVIDSRKGGDPDQSYVSRLFHKGDDAVLKKIGEEATEVVLAAKDVRQGGAPSALVGEVADLWFHCLVM
LSHFDLSPADVIAELERREGLSGIEEKALRKRREREENGG

Specific function: Histidine biosynthesis; second step. Histidine biosynthesis; third step. [C]

COG id: COG0140

COG function: function code E; Phosphoribosyl-ATP pyrophosphohydrolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PRA-PH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008179
- InterPro:   IPR021130 [H]

Pfam domain/function: PF01503 PRA-PH [H]

EC number: =3.6.1.31 [H]

Molecular weight: Translated: 13274; Mature: 13143

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQSTEDTLLRLAAVIDSRKGGDPDQSYVSRLFHKGDDAVLKKIGEEATEVVLAAKDVRQ
CCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
GGAPSALVGEVADLWFHCLVMLSHFDLSPADVIAELERREGLSGIEEKALRKRREREENG
CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
G
C
>Mature Secondary Structure 
TQSTEDTLLRLAAVIDSRKGGDPDQSYVSRLFHKGDDAVLKKIGEEATEVVLAAKDVRQ
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
GGAPSALVGEVADLWFHCLVMLSHFDLSPADVIAELERREGLSGIEEKALRKRREREENG
CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA