Click here to switch to the map view.

The map label for this gene is murA [H]

Identifier: 116688447

GI number: 116688447

Start: 472863

End: 474212

Strand: Direct

Name: murA [H]

Synonym: Bcen2424_0423

Alternate gene names: 116688447

Gene position: 472863-474212 (Clockwise)

Preceding gene: 116688446

Following gene: 116688448

Centisome position: 13.57

GC content: 68.15

Gene sequence:

>1350_bases
GTGCAAGTCACCGTCAACGAGCGCGACGCCGTCCAGAGCGTCGCCACGGCACACCCGGCCGCCAACGGGGAATCGCAGGG
ACAGGGGATGGACAAGCTCGCGATCGAAGGCGGTAACCGCCTGTCGGGCGAGATCGTCGTGTCGGGCGCGAAGAACGCCG
CGCTGCCGATCCTGTGCGCGGGGCTGCTCACCGCCGATCCGGTCGATCTCGACAACGTGCCGAACCTGAAGGACGTGCGC
ACGACGCTGAAGGTGCTGAACCAGATGGGGGTGAAGAGCGAGACCGACGGCTGCCGCGTGCAGCTCGACGCGTCGCGCGT
CGACAACCTCGTCGCGCCGTACGAGCTCGTGAAGACGATGCGCGCGTCGATCCTCGTGCTCGGGCCGCTGCTCGCGCGCT
TCGGCGAGGCGAAGGTGTCGCTGCCGGGCGGCTGCGCGATCGGCGCGCGACCGGTCGACCAGCACATCAAGGGCCTGCAG
GCGATGGGCGCGGAGATCAGCATCGAGCACGGCTTCATCGAAGCGCGCGCGAAGCGCCTGAAAGGCGCGCGCATCGTGAC
CGACATGATCACGGTGACGGGGACCGAAAACCTGCTGATGGCCGCGACGCTCGCCGACGGCGAGACGGTGATCGAAAACG
CCGCGCGCGAGCCGGAAGTGAGCGATCTCGCACACTTGCTGGTCGCGATGGGCGCGAAAATCGATGGCATCGGCACCGAT
CGCCTCGTGATCCAGGGCGTCGAGCGGCTGCACGGCGCGCGTCATTCGGTGATCCCCGACCGTATCGAGGCCGGCACGTT
CCTGTGCGCGGTCGCGGCGGCCGGCGGCGACGTGATGCTGACGGGCGTGCGCCCGCACATCCTCGACGCGGTGATCGACA
AGCTGCGCGAAGCCGGCGTGTCGATCGAGGAAGGCGACAGCTGGCTGCGCGTGAAGATGGACCGCCGCCCGTCGGCGGTG
ACGATCCGCACGTCGGAATATCCGGCGTTCCCGACCGACATGCAGGCGCAGTTCATGGCCCTCAATACGGTCGCGACGGG
CACCGCGCAGGTCGTCGAAACCATTTTCGAGAACCGCTTCATGCACGTGCAGGAGCTGAACCGGCTCGGCGCGAACATCA
CGATCGACGGCAACACGGCGCTCGTAACCGGCGTCGACAAGCTGTCCGGCGCGAACGTGATGGCGACCGACCTGCGTGCG
TCGGCGAGCCTCGTGATCGCCGGTCTGCGCGCCGACGGCGAAACGCTCGTCGACCGCATCTATCACCTGGACCGCGGCTA
CGACCGCATGGAAGCCAAACTGACCGCCGTCGGCGCGAACGTGCGCCGCCTTTCCGGGAGCCAAGCATGA

Upstream 100 bases:

>100_bases
ATGCGGCGCTCGGCGATCGCATGAAGCAGGAAATTCACGCGCTCAGCATGAAGACGCTGACGCCCGCCGAATGGCAGAAC
GCATAAACGGAAATCACTGA

Downstream 100 bases:

>100_bases
CCGCGCCGCTGACCCTCGCCCTGTCGAAGGGCCGGATTTTCGAGGAAACCCTGCCGCTGTTGGCAGCCGCCGGCGTGCAG
GTGGCCGAGGACCCGGAAAC

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MQVTVNERDAVQSVATAHPAANGESQGQGMDKLAIEGGNRLSGEIVVSGAKNAALPILCAGLLTADPVDLDNVPNLKDVR
TTLKVLNQMGVKSETDGCRVQLDASRVDNLVAPYELVKTMRASILVLGPLLARFGEAKVSLPGGCAIGARPVDQHIKGLQ
AMGAEISIEHGFIEARAKRLKGARIVTDMITVTGTENLLMAATLADGETVIENAAREPEVSDLAHLLVAMGAKIDGIGTD
RLVIQGVERLHGARHSVIPDRIEAGTFLCAVAAAGGDVMLTGVRPHILDAVIDKLREAGVSIEEGDSWLRVKMDRRPSAV
TIRTSEYPAFPTDMQAQFMALNTVATGTAQVVETIFENRFMHVQELNRLGANITIDGNTALVTGVDKLSGANVMATDLRA
SASLVIAGLRADGETLVDRIYHLDRGYDRMEAKLTAVGANVRRLSGSQA

Sequences:

>Translated_449_residues
MQVTVNERDAVQSVATAHPAANGESQGQGMDKLAIEGGNRLSGEIVVSGAKNAALPILCAGLLTADPVDLDNVPNLKDVR
TTLKVLNQMGVKSETDGCRVQLDASRVDNLVAPYELVKTMRASILVLGPLLARFGEAKVSLPGGCAIGARPVDQHIKGLQ
AMGAEISIEHGFIEARAKRLKGARIVTDMITVTGTENLLMAATLADGETVIENAAREPEVSDLAHLLVAMGAKIDGIGTD
RLVIQGVERLHGARHSVIPDRIEAGTFLCAVAAAGGDVMLTGVRPHILDAVIDKLREAGVSIEEGDSWLRVKMDRRPSAV
TIRTSEYPAFPTDMQAQFMALNTVATGTAQVVETIFENRFMHVQELNRLGANITIDGNTALVTGVDKLSGANVMATDLRA
SASLVIAGLRADGETLVDRIYHLDRGYDRMEAKLTAVGANVRRLSGSQA
>Mature_449_residues
MQVTVNERDAVQSVATAHPAANGESQGQGMDKLAIEGGNRLSGEIVVSGAKNAALPILCAGLLTADPVDLDNVPNLKDVR
TTLKVLNQMGVKSETDGCRVQLDASRVDNLVAPYELVKTMRASILVLGPLLARFGEAKVSLPGGCAIGARPVDQHIKGLQ
AMGAEISIEHGFIEARAKRLKGARIVTDMITVTGTENLLMAATLADGETVIENAAREPEVSDLAHLLVAMGAKIDGIGTD
RLVIQGVERLHGARHSVIPDRIEAGTFLCAVAAAGGDVMLTGVRPHILDAVIDKLREAGVSIEEGDSWLRVKMDRRPSAV
TIRTSEYPAFPTDMQAQFMALNTVATGTAQVVETIFENRFMHVQELNRLGANITIDGNTALVTGVDKLSGANVMATDLRA
SASLVIAGLRADGETLVDRIYHLDRGYDRMEAKLTAVGANVRRLSGSQA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=419, Percent_Identity=58.7112171837709, Blast_Score=498, Evalue=1e-142,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 47572; Mature: 47572

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVTVNERDAVQSVATAHPAANGESQGQGMDKLAIEGGNRLSGEIVVSGAKNAALPILCA
CEEECCHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCEECCEEEEECCCCCCHHHHHH
GLLTADPVDLDNVPNLKDVRTTLKVLNQMGVKSETDGCRVQLDASRVDNLVAPYELVKTM
HHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHCCCCCHHHHHHHH
RASILVLGPLLARFGEAKVSLPGGCAIGARPVDQHIKGLQAMGAEISIEHGFIEARAKRL
HHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHC
KGARIVTDMITVTGTENLLMAATLADGETVIENAAREPEVSDLAHLLVAMGAKIDGIGTD
CCCEEEEEEEEECCCCCEEEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCC
RLVIQGVERLHGARHSVIPDRIEAGTFLCAVAAAGGDVMLTGVRPHILDAVIDKLREAGV
HHHHHHHHHHCCCCCCCCCCHHCCCCEEEEEEECCCCEEEECCCHHHHHHHHHHHHHCCC
SIEEGDSWLRVKMDRRPSAVTIRTSEYPAFPTDMQAQFMALNTVATGTAQVVETIFENRF
CEECCCCEEEEEECCCCCEEEEECCCCCCCCCCCCHHHEEEHHHCCCHHHHHHHHHHHCC
MHVQELNRLGANITIDGNTALVTGVDKLSGANVMATDLRASASLVIAGLRADGETLVDRI
HHHHHHHHCCCEEEECCCEEEEEECHHHCCCCEEEHHHHCCCEEEEEEECCCHHHHHHHH
YHLDRGYDRMEAKLTAVGANVRRLSGSQA
HHHCCCHHHHHHHHHHHCCCHHHCCCCCC
>Mature Secondary Structure
MQVTVNERDAVQSVATAHPAANGESQGQGMDKLAIEGGNRLSGEIVVSGAKNAALPILCA
CEEECCHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCEECCEEEEECCCCCCHHHHHH
GLLTADPVDLDNVPNLKDVRTTLKVLNQMGVKSETDGCRVQLDASRVDNLVAPYELVKTM
HHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHCCCCCHHHHHHHH
RASILVLGPLLARFGEAKVSLPGGCAIGARPVDQHIKGLQAMGAEISIEHGFIEARAKRL
HHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHC
KGARIVTDMITVTGTENLLMAATLADGETVIENAAREPEVSDLAHLLVAMGAKIDGIGTD
CCCEEEEEEEEECCCCCEEEEEEECCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCC
RLVIQGVERLHGARHSVIPDRIEAGTFLCAVAAAGGDVMLTGVRPHILDAVIDKLREAGV
HHHHHHHHHHCCCCCCCCCCHHCCCCEEEEEEECCCCEEEECCCHHHHHHHHHHHHHCCC
SIEEGDSWLRVKMDRRPSAVTIRTSEYPAFPTDMQAQFMALNTVATGTAQVVETIFENRF
CEECCCCEEEEEECCCCCEEEEECCCCCCCCCCCCHHHEEEHHHCCCHHHHHHHHHHHCC
MHVQELNRLGANITIDGNTALVTGVDKLSGANVMATDLRASASLVIAGLRADGETLVDRI
HHHHHHHHCCCEEEECCCEEEEEECHHHCCCCEEEHHHHCCCEEEEEEECCCHHHHHHHH
YHLDRGYDRMEAKLTAVGANVRRLSGSQA
HHHCCCHHHHHHHHHHHCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA