| Definition | Burkholderia cenocepacia HI2424 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_008542 |
| Length | 3,483,902 |
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The map label for this gene is livF [H]
Identifier: 116688116
GI number: 116688116
Start: 95149
End: 95904
Strand: Direct
Name: livF [H]
Synonym: Bcen2424_0092
Alternate gene names: 116688116
Gene position: 95149-95904 (Clockwise)
Preceding gene: 116688115
Following gene: 116688117
Centisome position: 2.73
GC content: 66.93
Gene sequence:
>756_bases ATGACGGACACGACGATGCCGATTCTCGAAGTGCGCGGGCTGGCGGTGCGGTACGGGAAGGTCGAGGCGCTGCACGGGGC CGCAATCAAGGTCGGGGCGGGGCAGATCGTCAGCGTGATCGGCCCGAATGGCGCCGGTAAATCGACGCTGCTGAACGCGA TCATGGGGGCGCTGCCGGTAACGGGGCATGCGTCGGGCGCGGTCGTGTATCGCGGCAACGACGTCGGCGCGTTGCCGGTC GAGCAGCGTGTCGCCCGCGGCATGTGCCTCGTACCGGAGAAGCGCGAGCTGTTCAGCACGATGACGGTCGAAGACAACCT CGTGCTGGGCGCGTATCGGCGCAAGCAGGCGGGGGAATCGAACTTCCTCGATCAGCTCGATCACGTGTTCGCGCTGTTTC CGCGGCTGAAGGAGCGCCGCAGGCAGGCGGCCGGCACGTTGTCCGGCGGCGAGCGGCAGATGCTGGCGGTCGGCCGTGCG CTGATGGGCAAGCCCGACCTGCTGATGCTCGACGAGCCGAGCCTCGGGCTGGCGCCGCTGATCGTGAAGGAGATCTTTCA TATCATCAGCGCGTTGCGCGGCACCGGCGTTGCGACGCTGCTGATCGAGCAGAACGCGCGGGCTGCGTTGCAGATCTCGG ACTACGGCTACGTGCTGGAGACGGGCGAGTTTGCGCTGGAAGGGCCGGCGGCCGAGCTTGCGCAGAATCCGCAGGTGATC GAGACGTATCTCGGGTTGGCGAAGAAGACGGCTTGA
Upstream 100 bases:
>100_bases TGGTGGTGATGGAATTCGGCACGCGGATCGCGGAAGGGCTGCCGCAGGATGTGCAGCAGGACCCGGCCGTGCTGGAAGCG TATCTGGGCGGGGTGGAGTG
Downstream 100 bases:
>100_bases TTGGTGACGCGGTGGGCGGGAAACGGGCGGCGTGTTTCACGTGAAACACGCCGTTTTTGTTTGTGAGCCACGAGTGTCGA GGCTTCGACGGTTCAAGGCC
Product: ABC transporter related
Products: ADP; phosphate; L-leucine [Cytoplasm]; ADP; L-valine [Cytoplasm]; L-iso-leucine [Cytoplasm] [C]
Alternate protein names: LIV-I protein F [H]
Number of amino acids: Translated: 251; Mature: 250
Protein sequence:
>251_residues MTDTTMPILEVRGLAVRYGKVEALHGAAIKVGAGQIVSVIGPNGAGKSTLLNAIMGALPVTGHASGAVVYRGNDVGALPV EQRVARGMCLVPEKRELFSTMTVEDNLVLGAYRRKQAGESNFLDQLDHVFALFPRLKERRRQAAGTLSGGERQMLAVGRA LMGKPDLLMLDEPSLGLAPLIVKEIFHIISALRGTGVATLLIEQNARAALQISDYGYVLETGEFALEGPAAELAQNPQVI ETYLGLAKKTA
Sequences:
>Translated_251_residues MTDTTMPILEVRGLAVRYGKVEALHGAAIKVGAGQIVSVIGPNGAGKSTLLNAIMGALPVTGHASGAVVYRGNDVGALPV EQRVARGMCLVPEKRELFSTMTVEDNLVLGAYRRKQAGESNFLDQLDHVFALFPRLKERRRQAAGTLSGGERQMLAVGRA LMGKPDLLMLDEPSLGLAPLIVKEIFHIISALRGTGVATLLIEQNARAALQISDYGYVLETGEFALEGPAAELAQNPQVI ETYLGLAKKTA >Mature_250_residues TDTTMPILEVRGLAVRYGKVEALHGAAIKVGAGQIVSVIGPNGAGKSTLLNAIMGALPVTGHASGAVVYRGNDVGALPVE QRVARGMCLVPEKRELFSTMTVEDNLVLGAYRRKQAGESNFLDQLDHVFALFPRLKERRRQAAGTLSGGERQMLAVGRAL MGKPDLLMLDEPSLGLAPLIVKEIFHIISALRGTGVATLLIEQNARAALQISDYGYVLETGEFALEGPAAELAQNPQVIE TYLGLAKKTA
Specific function: Component of the leucine-specific transport system [H]
COG id: COG0410
COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI153792144, Length=165, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI45446740, Length=167, Percent_Identity=31.7365269461078, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI27436953, Length=216, Percent_Identity=28.2407407407407, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI47078218, Length=167, Percent_Identity=31.7365269461078, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI27262624, Length=175, Percent_Identity=30.8571428571429, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI27262626, Length=175, Percent_Identity=30.8571428571429, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI46592915, Length=218, Percent_Identity=28.4403669724771, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI46592956, Length=218, Percent_Identity=28.4403669724771, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI46592964, Length=218, Percent_Identity=28.4403669724771, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI46592898, Length=218, Percent_Identity=28.4403669724771, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI27881501, Length=213, Percent_Identity=28.169014084507, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI30795238, Length=213, Percent_Identity=28.169014084507, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI46592971, Length=218, Percent_Identity=28.4403669724771, Blast_Score=79, Evalue=6e-15, Organism=Homo sapiens, GI46592978, Length=218, Percent_Identity=28.4403669724771, Blast_Score=79, Evalue=6e-15, Organism=Homo sapiens, GI27477115, Length=171, Percent_Identity=30.4093567251462, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI21536376, Length=233, Percent_Identity=27.8969957081545, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI105990541, Length=159, Percent_Identity=31.4465408805031, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI31657092, Length=196, Percent_Identity=27.0408163265306, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI116734710, Length=208, Percent_Identity=29.3269230769231, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI255708477, Length=252, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI148612844, Length=252, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI11967969, Length=235, Percent_Identity=27.6595744680851, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI11967971, Length=228, Percent_Identity=25.8771929824561, Blast_Score=64, Evalue=1e-10, Organism=Escherichia coli, GI87082268, Length=238, Percent_Identity=45.3781512605042, Blast_Score=206, Evalue=1e-54, Organism=Escherichia coli, GI1789864, Length=258, Percent_Identity=32.5581395348837, Blast_Score=125, Evalue=2e-30, Organism=Escherichia coli, GI1789593, Length=240, Percent_Identity=30, Blast_Score=121, Evalue=4e-29, Organism=Escherichia coli, GI1787792, Length=258, Percent_Identity=29.8449612403101, Blast_Score=101, Evalue=4e-23, Organism=Escherichia coli, GI1787029, Length=240, Percent_Identity=27.0833333333333, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1788472, Length=247, Percent_Identity=28.3400809716599, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1790162, Length=250, Percent_Identity=26.8, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI48994943, Length=242, Percent_Identity=30.1652892561983, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI1790190, Length=212, Percent_Identity=31.6037735849057, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI87081791, Length=232, Percent_Identity=25.4310344827586, Blast_Score=88, Evalue=5e-19, Organism=Escherichia coli, GI1789991, Length=241, Percent_Identity=26.1410788381743, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1787089, Length=245, Percent_Identity=26.9387755102041, Blast_Score=85, Evalue=5e-18, Organism=Escherichia coli, GI1788761, Length=242, Percent_Identity=26.4462809917355, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1789672, Length=225, Percent_Identity=25.7777777777778, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI87081782, Length=237, Percent_Identity=29.535864978903, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI1786253, Length=228, Percent_Identity=29.3859649122807, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI1787370, Length=242, Percent_Identity=26.0330578512397, Blast_Score=81, Evalue=6e-17, Organism=Escherichia coli, GI1787105, Length=248, Percent_Identity=28.2258064516129, Blast_Score=79, Evalue=4e-16, Organism=Escherichia coli, GI48995001, Length=242, Percent_Identity=28.099173553719, Blast_Score=79, Evalue=4e-16, Organism=Escherichia coli, GI1786319, Length=200, Percent_Identity=33.5, Blast_Score=78, Evalue=4e-16, Organism=Escherichia coli, GI1787712, Length=222, Percent_Identity=28.3783783783784, Blast_Score=77, Evalue=9e-16, Organism=Escherichia coli, GI1790525, Length=246, Percent_Identity=24.7967479674797, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI87081709, Length=254, Percent_Identity=24.8031496062992, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1788225, Length=249, Percent_Identity=25.7028112449799, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1786398, Length=222, Percent_Identity=26.5765765765766, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1789586, Length=245, Percent_Identity=25.3061224489796, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1790467, Length=238, Percent_Identity=28.9915966386555, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1788210, Length=211, Percent_Identity=29.3838862559242, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1786872, Length=248, Percent_Identity=25.4032258064516, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI1787759, Length=253, Percent_Identity=25.296442687747, Blast_Score=71, Evalue=6e-14, Organism=Escherichia coli, GI87081834, Length=220, Percent_Identity=28.6363636363636, Blast_Score=71, Evalue=8e-14, Organism=Escherichia coli, GI1788053, Length=173, Percent_Identity=30.0578034682081, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1788644, Length=249, Percent_Identity=31.3253012048193, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1788897, Length=225, Percent_Identity=26.2222222222222, Blast_Score=69, Evalue=2e-13, Organism=Escherichia coli, GI1790544, Length=250, Percent_Identity=24.8, Blast_Score=69, Evalue=2e-13, Organism=Escherichia coli, GI1788450, Length=231, Percent_Identity=24.6753246753247, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI87082267, Length=222, Percent_Identity=27.4774774774775, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1786698, Length=168, Percent_Identity=32.1428571428571, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1786563, Length=218, Percent_Identity=27.5229357798165, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1787112, Length=217, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=4e-12, Organism=Escherichia coli, GI1789032, Length=242, Percent_Identity=28.5123966942149, Blast_Score=65, Evalue=6e-12, Organism=Escherichia coli, GI48994883, Length=244, Percent_Identity=25.4098360655738, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1790739, Length=237, Percent_Identity=26.1603375527426, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1788506, Length=218, Percent_Identity=25.6880733944954, Blast_Score=62, Evalue=3e-11, Organism=Escherichia coli, GI1788165, Length=244, Percent_Identity=24.5901639344262, Blast_Score=62, Evalue=3e-11, Organism=Escherichia coli, GI1787972, Length=240, Percent_Identity=25.8333333333333, Blast_Score=61, Evalue=9e-11, Organism=Caenorhabditis elegans, GI71983523, Length=213, Percent_Identity=29.1079812206573, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI71983516, Length=213, Percent_Identity=29.1079812206573, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI71983510, Length=213, Percent_Identity=29.1079812206573, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17510237, Length=231, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI193208177, Length=224, Percent_Identity=27.2321428571429, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI115533608, Length=168, Percent_Identity=30.952380952381, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI193209708, Length=223, Percent_Identity=27.8026905829596, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17565586, Length=174, Percent_Identity=29.8850574712644, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI212646699, Length=260, Percent_Identity=26.5384615384615, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI115532730, Length=222, Percent_Identity=26.5765765765766, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17552232, Length=206, Percent_Identity=28.6407766990291, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI193202349, Length=253, Percent_Identity=25.6916996047431, Blast_Score=64, Evalue=9e-11, Organism=Saccharomyces cerevisiae, GI6324498, Length=216, Percent_Identity=27.7777777777778, Blast_Score=67, Evalue=4e-12, Organism=Drosophila melanogaster, GI24666092, Length=188, Percent_Identity=31.9148936170213, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI19920532, Length=215, Percent_Identity=28.8372093023256, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI24580930, Length=215, Percent_Identity=28.8372093023256, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI221512771, Length=227, Percent_Identity=25.5506607929515, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI28574533, Length=235, Percent_Identity=28.5106382978723, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI24643674, Length=222, Percent_Identity=25.2252252252252, Blast_Score=77, Evalue=8e-15, Organism=Drosophila melanogaster, GI28574150, Length=221, Percent_Identity=25.3393665158371, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI116007328, Length=221, Percent_Identity=25.3393665158371, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI85724858, Length=206, Percent_Identity=29.126213592233, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI85724856, Length=206, Percent_Identity=29.126213592233, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI24580547, Length=206, Percent_Identity=29.126213592233, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI24580551, Length=206, Percent_Identity=29.126213592233, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI24580549, Length=206, Percent_Identity=29.126213592233, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI24580545, Length=206, Percent_Identity=29.126213592233, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI24662800, Length=247, Percent_Identity=26.7206477732794, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI85816269, Length=219, Percent_Identity=27.3972602739726, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24580553, Length=219, Percent_Identity=27.3972602739726, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI85724864, Length=219, Percent_Identity=27.3972602739726, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24580555, Length=219, Percent_Identity=27.3972602739726, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI28573573, Length=227, Percent_Identity=25.9911894273128, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI28573571, Length=227, Percent_Identity=25.9911894273128, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI161076682, Length=219, Percent_Identity=26.9406392694064, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI161076684, Length=219, Percent_Identity=26.9406392694064, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24581617, Length=219, Percent_Identity=26.9406392694064, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24581615, Length=219, Percent_Identity=26.9406392694064, Blast_Score=67, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 26699; Mature: 26568
Theoretical pI: Translated: 8.44; Mature: 8.44
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 3.2 %Met (Translated Protein) 3.6 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTDTTMPILEVRGLAVRYGKVEALHGAAIKVGAGQIVSVIGPNGAGKSTLLNAIMGALPV CCCCCCHHHHHCCCEEECCCEEEECCCEEEECCCCEEEEECCCCCCHHHHHHHHHHHCCC TGHASGAVVYRGNDVGALPVEQRVARGMCLVPEKRELFSTMTVEDNLVLGAYRRKQAGES CCCCCCEEEEECCCCCCCCHHHHHHCCCCCCCCHHHHHHHHEECCCEEEEHHHHHCCCCH NFLDQLDHVFALFPRLKERRRQAAGTLSGGERQMLAVGRALMGKPDLLMLDEPSLGLAPL HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCHHHH IVKEIFHIISALRGTGVATLLIEQNARAALQISDYGYVLETGEFALEGPAAELAQNPQVI HHHHHHHHHHHHHCCCEEEEEEECCCCEEEEECCCCEEEECCCEEECCCHHHHHCCCHHH ETYLGLAKKTA HHHHHHHHCCC >Mature Secondary Structure TDTTMPILEVRGLAVRYGKVEALHGAAIKVGAGQIVSVIGPNGAGKSTLLNAIMGALPV CCCCCHHHHHCCCEEECCCEEEECCCEEEECCCCEEEEECCCCCCHHHHHHHHHHHCCC TGHASGAVVYRGNDVGALPVEQRVARGMCLVPEKRELFSTMTVEDNLVLGAYRRKQAGES CCCCCCEEEEECCCCCCCCHHHHHHCCCCCCCCHHHHHHHHEECCCEEEEHHHHHCCCCH NFLDQLDHVFALFPRLKERRRQAAGTLSGGERQMLAVGRALMGKPDLLMLDEPSLGLAPL HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCHHHH IVKEIFHIISALRGTGVATLLIEQNARAALQISDYGYVLETGEFALEGPAAELAQNPQVI HHHHHHHHHHHHHCCCEEEEEEECCCCEEEEECCCCEEEECCCEEECCCHHHHHCCCHHH ETYLGLAKKTA HHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; L-leucine [Periplasm]; H2O; ATP; L-valine [Periplasm]; L-iso-leucine [Periplasm] [C]
Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2195019; 8041620; 9278503 [H]