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The map label for this gene is qseC [H]

Identifier: 116688098

GI number: 116688098

Start: 76270

End: 77754

Strand: Reverse

Name: qseC [H]

Synonym: Bcen2424_0074

Alternate gene names: 116688098

Gene position: 77754-76270 (Counterclockwise)

Preceding gene: 116688099

Following gene: 116688089

Centisome position: 2.23

GC content: 70.44

Gene sequence:

>1485_bases
ATGTCTCCTGATCCGGCTGTGACCACCAGCCTGCGCCGCTCGCTGCTCCGGCGCCTCGCCGCCCCGCTGTCGATGCTCGC
GCTGATGAGCGGCCTGATCGCCTACTGGCTCGCGTGGCAATACACGCAGCACGTGATCGACCGCTCGCTCGCCGATCTCG
CGACCGCCATCTCCAAACAGATCCAGATCGCCGGCCCCGACGCGCCGTTCACGGTGCCGCCGCTCGCACAGGCGATGTTC
TCCGATCCGGCCGAAGCGCTGATCTACCGGATCAGCGACGGCGAGCAGGAACTCGCCGGCGACCCGAAGCTGCCGCTGCA
GGGCATCAACGTGCGCCGCATGCATCACGCGTACGTGTTCGAGGCCGAGTACGACAACCGCGCGGTGCGGGTCGCGCAGG
TGCGCGTCGACGACGTCGAGGGCGGCAAGCCGATGGTCGTCGAAGTCGCGCAGCCGGTGCGGCACCGCTACCGGATCGCG
GCTGAATTCCTCGTTGCGATCATGATGCCGCTGCTCCTGCTGCTGCTCGCCGGCTGGGGCATCGTGTGGCGCGTGGTGAA
CCAGCAGCTCGGCCCGCTCACGCATCTCGCCGATTCGCTGAACCGGCAGACCCACACGTCGCTGGAGCCGGTCGACGAAA
CCGACGTGCCGCTGGAGATCCGGCCGCTGACGAGCGCGATGAACGCGCTGCTCGGCCGCCTCAAGACCGCGCTCGACGCG
CAGCGCAAGTTCATCGCCGATGCCGCTCACCAGTTGCGCACGCCGCTCACCGCGGTGAAGCTACATGCCGAGCAGGCGGC
CGTCGCGCGCGACCCGCACCAGACCTTCGCCGCGGTGCGTGAGCTGCGCGCAGCGGCCGACCGGGCGGTGCGGCTGTCCA
ACCAGTTGCTGTCGCTCGCGCGGGCCGAGCCGGGCGAGCAGGCCGCGCGCTTCGTCGACGTCGATCTCGCGGCGATGGCG
TTCGAGACCGGCGCCGAATGGGTGCCGCGCGCGCTCGCGTCGCATGTCGACCTCGGCTTCCAGCGCAGCGACGAGCCGGG
CGACGACGAGAAGCTGATCGTACGCGGCAACCCCGTGCTGTTGCGCGAGGTGATCGCGAACCTGCTCGACAATGCGCTGA
AGTACGTGCCGCTCGCGCGGCCGGACGGCGCGCGGATCACGGTGAACGTCGCGCGCGCCTCGCTCGAGGGCAGCCAGCCG
GCCGCCGAGATCGTCGTCGAGGACAACGGCCCCGGCGTGCCCGCGAACCAGCAGGCCGACCTGTTCAAGCGCTTCTTCCG
CGGCGACGCGCAAAGCGGCAATGGTGTCGAGACGGGCGCCGGGCTCGGGCTCGCCATCGTGCACGACATCATCGCGATGC
ATGGCGGCACCGTGTCGTACGAGGATGCATCGGAAGGCGGCTCGCGCTTCGTGGTGAGGGTACCGCTCGCCGCGCATACG
GAGCGGCCGGCCAGCGAAACGCCGGCTGCGGCGCCGACGCACTGA

Upstream 100 bases:

>100_bases
CCGCGTGCCGCCGACGCGCATGCGTACGGCTTCCGCGTCGCCGCCCCGCGCACGACCGCGCCGCTCCCCGTGAGCGGCGC
TTATCCATTTGCCCGTCGAA

Downstream 100 bases:

>100_bases
GCAACGCGATTGTCGGCGGGCAACGGTTGGCCCGTCGACCGGGCCGCCCGCCGGAACAGGAACGGAAAGACGGAAAGCGG
ATGACGCGCCGCGACGACGC

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 494; Mature: 493

Protein sequence:

>494_residues
MSPDPAVTTSLRRSLLRRLAAPLSMLALMSGLIAYWLAWQYTQHVIDRSLADLATAISKQIQIAGPDAPFTVPPLAQAMF
SDPAEALIYRISDGEQELAGDPKLPLQGINVRRMHHAYVFEAEYDNRAVRVAQVRVDDVEGGKPMVVEVAQPVRHRYRIA
AEFLVAIMMPLLLLLLAGWGIVWRVVNQQLGPLTHLADSLNRQTHTSLEPVDETDVPLEIRPLTSAMNALLGRLKTALDA
QRKFIADAAHQLRTPLTAVKLHAEQAAVARDPHQTFAAVRELRAAADRAVRLSNQLLSLARAEPGEQAARFVDVDLAAMA
FETGAEWVPRALASHVDLGFQRSDEPGDDEKLIVRGNPVLLREVIANLLDNALKYVPLARPDGARITVNVARASLEGSQP
AAEIVVEDNGPGVPANQQADLFKRFFRGDAQSGNGVETGAGLGLAIVHDIIAMHGGTVSYEDASEGGSRFVVRVPLAAHT
ERPASETPAAAPTH

Sequences:

>Translated_494_residues
MSPDPAVTTSLRRSLLRRLAAPLSMLALMSGLIAYWLAWQYTQHVIDRSLADLATAISKQIQIAGPDAPFTVPPLAQAMF
SDPAEALIYRISDGEQELAGDPKLPLQGINVRRMHHAYVFEAEYDNRAVRVAQVRVDDVEGGKPMVVEVAQPVRHRYRIA
AEFLVAIMMPLLLLLLAGWGIVWRVVNQQLGPLTHLADSLNRQTHTSLEPVDETDVPLEIRPLTSAMNALLGRLKTALDA
QRKFIADAAHQLRTPLTAVKLHAEQAAVARDPHQTFAAVRELRAAADRAVRLSNQLLSLARAEPGEQAARFVDVDLAAMA
FETGAEWVPRALASHVDLGFQRSDEPGDDEKLIVRGNPVLLREVIANLLDNALKYVPLARPDGARITVNVARASLEGSQP
AAEIVVEDNGPGVPANQQADLFKRFFRGDAQSGNGVETGAGLGLAIVHDIIAMHGGTVSYEDASEGGSRFVVRVPLAAHT
ERPASETPAAAPTH
>Mature_493_residues
SPDPAVTTSLRRSLLRRLAAPLSMLALMSGLIAYWLAWQYTQHVIDRSLADLATAISKQIQIAGPDAPFTVPPLAQAMFS
DPAEALIYRISDGEQELAGDPKLPLQGINVRRMHHAYVFEAEYDNRAVRVAQVRVDDVEGGKPMVVEVAQPVRHRYRIAA
EFLVAIMMPLLLLLLAGWGIVWRVVNQQLGPLTHLADSLNRQTHTSLEPVDETDVPLEIRPLTSAMNALLGRLKTALDAQ
RKFIADAAHQLRTPLTAVKLHAEQAAVARDPHQTFAAVRELRAAADRAVRLSNQLLSLARAEPGEQAARFVDVDLAAMAF
ETGAEWVPRALASHVDLGFQRSDEPGDDEKLIVRGNPVLLREVIANLLDNALKYVPLARPDGARITVNVARASLEGSQPA
AEIVVEDNGPGVPANQQADLFKRFFRGDAQSGNGVETGAGLGLAIVHDIIAMHGGTVSYEDASEGGSRFVVRVPLAAHTE
RPASETPAAAPTH

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=470, Percent_Identity=28.2978723404255, Blast_Score=135, Evalue=9e-33,
Organism=Escherichia coli, GI1790551, Length=323, Percent_Identity=30.9597523219814, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1786783, Length=340, Percent_Identity=26.7647058823529, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1786600, Length=285, Percent_Identity=31.9298245614035, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786912, Length=245, Percent_Identity=31.8367346938775, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788393, Length=299, Percent_Identity=27.0903010033445, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI145693157, Length=243, Percent_Identity=27.9835390946502, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790346, Length=271, Percent_Identity=27.3062730627306, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789149, Length=255, Percent_Identity=27.0588235294118, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1788713, Length=276, Percent_Identity=24.2753623188406, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787894, Length=268, Percent_Identity=27.9850746268657, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1790861, Length=294, Percent_Identity=27.5510204081633, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1789808, Length=309, Percent_Identity=26.8608414239482, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1790436, Length=254, Percent_Identity=28.740157480315, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87081816, Length=366, Percent_Identity=26.775956284153, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87082128, Length=481, Percent_Identity=24.948024948025, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1788549, Length=236, Percent_Identity=26.6949152542373, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53527; Mature: 53396

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPDPAVTTSLRRSLLRRLAAPLSMLALMSGLIAYWLAWQYTQHVIDRSLADLATAISKQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IQIAGPDAPFTVPPLAQAMFSDPAEALIYRISDGEQELAGDPKLPLQGINVRRMHHAYVF
EEEECCCCCCCCCHHHHHHHCCCHHHEEEEECCCCHHHCCCCCCCCCCCCCEEEEEEEEE
EAEYDNRAVRVAQVRVDDVEGGKPMVVEVAQPVRHRYRIAAEFLVAIMMPLLLLLLAGWG
EEECCCCEEEEEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVWRVVNQQLGPLTHLADSLNRQTHTSLEPVDETDVPLEIRPLTSAMNALLGRLKTALDA
HHHHHHHHHHCHHHHHHHHHCHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
QRKFIADAAHQLRTPLTAVKLHAEQAAVARDPHQTFAAVRELRAAADRAVRLSNQLLSLA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAEPGEQAARFVDVDLAAMAFETGAEWVPRALASHVDLGFQRSDEPGDDEKLIVRGNPVL
HCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCHHH
LREVIANLLDNALKYVPLARPDGARITVNVARASLEGSQPAAEIVVEDNGPGVPANQQAD
HHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEHHCCCCCCCEEEEEECCCCCCCCCCHHH
LFKRFFRGDAQSGNGVETGAGLGLAIVHDIIAMHGGTVSYEDASEGGSRFVVRVPLAAHT
HHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEECCCCCCCCCEEEEEECHHHCC
ERPASETPAAAPTH
CCCCCCCCCCCCCC
>Mature Secondary Structure 
SPDPAVTTSLRRSLLRRLAAPLSMLALMSGLIAYWLAWQYTQHVIDRSLADLATAISKQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IQIAGPDAPFTVPPLAQAMFSDPAEALIYRISDGEQELAGDPKLPLQGINVRRMHHAYVF
EEEECCCCCCCCCHHHHHHHCCCHHHEEEEECCCCHHHCCCCCCCCCCCCCEEEEEEEEE
EAEYDNRAVRVAQVRVDDVEGGKPMVVEVAQPVRHRYRIAAEFLVAIMMPLLLLLLAGWG
EEECCCCEEEEEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVWRVVNQQLGPLTHLADSLNRQTHTSLEPVDETDVPLEIRPLTSAMNALLGRLKTALDA
HHHHHHHHHHCHHHHHHHHHCHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
QRKFIADAAHQLRTPLTAVKLHAEQAAVARDPHQTFAAVRELRAAADRAVRLSNQLLSLA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAEPGEQAARFVDVDLAAMAFETGAEWVPRALASHVDLGFQRSDEPGDDEKLIVRGNPVL
HCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCHHH
LREVIANLLDNALKYVPLARPDGARITVNVARASLEGSQPAAEIVVEDNGPGVPANQQAD
HHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEHHCCCCCCCEEEEEECCCCCCCCCCHHH
LFKRFFRGDAQSGNGVETGAGLGLAIVHDIIAMHGGTVSYEDASEGGSRFVVRVPLAAHT
HHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEECCCCCCCCCEEEEEECHHHCC
ERPASETPAAAPTH
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]