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The map label for this gene is ppaX [H]

Identifier: 116626916

GI number: 116626916

Start: 9898105

End: 9898794

Strand: Direct

Name: ppaX [H]

Synonym: Acid_7893

Alternate gene names: 116626916

Gene position: 9898105-9898794 (Clockwise)

Preceding gene: 116626905

Following gene: 116626926

Centisome position: 99.32

GC content: 62.75

Gene sequence:

>690_bases
TTGAGCCAAACTAAATTCATGCCCTTCCGTACTGTCCTCTTCGATTGGGACGGGACCCTCTGCGATTCCGGCGCCGCCCT
CTACCGCGCCTTCGAAAAATCCCTTGCCGATTTCGGCCTCTCCTTTACCCTCGACGAATACCAGCAGGTCTACACCCCCG
CCTGGTACCGCATGTATGAGGCCTTCAATCTCCCCAAGGAATCCTGGAGCCTGTGCGATCGCCGCTGGCTCCAACACTAC
GAAGGCGAGGAGCCGAACCTCCTTCCCGGCGCCCTCGCCGTCATCGACCACTGCCGCGCCGCCGGACTTCAGCTCGGGAT
CGTCACCGGCGCCAATCGCGACCGCATCCGCCAGGAATTCGCGCGGCTCGACCTCGCCTTCCCCGCCATCATTTGTCACG
AGGATGTCGTCGATCGCAAGCCGCATCCCGAAGGAATCGCCCGCGCCCTCGGAATCCTGAACGCACCGGCCTCCGGCTGC
TGCTTCGTCGGCGACGCTCCCGAGGATATCGAAATGGGGAAGCGCGCCGGAGTCTTCACCATCGGCGTGGTCAGCGAGTA
TATTCACCGCGCACGTCTCGAAGCCGCCGCGCCTGACCTGCTGCTCGAGACCATCGCCGATCTCCCTGGCGCGCTCGCTC
TTACAGGGAATTCAGATACGCAATCAGATCGGACATCTGTGGCGCCGTAA

Upstream 100 bases:

>100_bases
GTACTCACAACGGGCCGCGACCGTAAGGGAGCGCCGGTGCGCCCGACCATCCCGCTCACCCTCCCGCGCGAATCGCGACC
GTCAGGGAGCGATCTCTTAT

Downstream 100 bases:

>100_bases
ACCGCGGCCACGCCAGCTTCTTCTGCTTCATCATCTCGAGCATCTGCGGGCCGTGATCCCATAGCGCCGCAACCAGCGTG
ATGTCCGAATACGCCTCTTT

Product: HAD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MSQTKFMPFRTVLFDWDGTLCDSGAALYRAFEKSLADFGLSFTLDEYQQVYTPAWYRMYEAFNLPKESWSLCDRRWLQHY
EGEEPNLLPGALAVIDHCRAAGLQLGIVTGANRDRIRQEFARLDLAFPAIICHEDVVDRKPHPEGIARALGILNAPASGC
CFVGDAPEDIEMGKRAGVFTIGVVSEYIHRARLEAAAPDLLLETIADLPGALALTGNSDTQSDRTSVAP

Sequences:

>Translated_229_residues
MSQTKFMPFRTVLFDWDGTLCDSGAALYRAFEKSLADFGLSFTLDEYQQVYTPAWYRMYEAFNLPKESWSLCDRRWLQHY
EGEEPNLLPGALAVIDHCRAAGLQLGIVTGANRDRIRQEFARLDLAFPAIICHEDVVDRKPHPEGIARALGILNAPASGC
CFVGDAPEDIEMGKRAGVFTIGVVSEYIHRARLEAAAPDLLLETIADLPGALALTGNSDTQSDRTSVAP
>Mature_228_residues
SQTKFMPFRTVLFDWDGTLCDSGAALYRAFEKSLADFGLSFTLDEYQQVYTPAWYRMYEAFNLPKESWSLCDRRWLQHYE
GEEPNLLPGALAVIDHCRAAGLQLGIVTGANRDRIRQEFARLDLAFPAIICHEDVVDRKPHPEGIARALGILNAPASGCC
FVGDAPEDIEMGKRAGVFTIGVVSEYIHRARLEAAAPDLLLETIADLPGALALTGNSDTQSDRTSVAP

Specific function: Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool [H]

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. PpaX family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=253, Percent_Identity=28.4584980237154, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 25311; Mature: 25180

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQTKFMPFRTVLFDWDGTLCDSGAALYRAFEKSLADFGLSFTLDEYQQVYTPAWYRMYE
CCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
AFNLPKESWSLCDRRWLQHYEGEEPNLLPGALAVIDHCRAAGLQLGIVTGANRDRIRQEF
HHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHH
ARLDLAFPAIICHEDVVDRKPHPEGIARALGILNAPASGCCFVGDAPEDIEMGKRAGVFT
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEECCCCHHHHHCCCCCEEH
IGVVSEYIHRARLEAAAPDLLLETIADLPGALALTGNSDTQSDRTSVAP
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
SQTKFMPFRTVLFDWDGTLCDSGAALYRAFEKSLADFGLSFTLDEYQQVYTPAWYRMYE
CCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
AFNLPKESWSLCDRRWLQHYEGEEPNLLPGALAVIDHCRAAGLQLGIVTGANRDRIRQEF
HHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHH
ARLDLAFPAIICHEDVVDRKPHPEGIARALGILNAPASGCCFVGDAPEDIEMGKRAGVFT
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEECCCCHHHHHCCCCCEEH
IGVVSEYIHRARLEAAAPDLLLETIADLPGALALTGNSDTQSDRTSVAP
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]