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The map label for this gene is ykoU [H]

Identifier: 116626869

GI number: 116626869

Start: 9839542

End: 9841434

Strand: Direct

Name: ykoU [H]

Synonym: Acid_7844

Alternate gene names: 116626869

Gene position: 9839542-9841434 (Clockwise)

Preceding gene: 116626868

Following gene: 116626871

Centisome position: 98.73

GC content: 60.8

Gene sequence:

>1893_bases
ATGCCTGCGGAAATGCCGGCGTCGATCGAGCCGATGAAGGCGACGATTGCCGAGCGCGTGCCGCGTGGGGACGAGTGGCT
GTTCGAGATTAAATGGGATGGGGTGCGAGCGGTCGCTTTTTTGGATAACGAAGAAGTGCGGCTGCAGGCGCGGAGCGGAT
TGCGCTGCGAGCGGCAATACCCGGAGCTGGCGGTGCTGCCGCATCACGTGGCCGCGGCGCGCGCGATTCTGGACGGCGAA
ATCGCGGTGCTGGATGCCAAAGGCGTTTCCCAGTTTCATTTGATTCAGCCGCGCATCGCGAATAGCGATCCGAATACGAT
TGCCCATCTGGTGCGCTCCACGCCGGTGGTGTATTTCGCGTTCGACCTGCTCTACCTGGATGGCTACGATCTGCGCAACG
TGGACCTGGCGAAGCGTCGCGAACTGTTGGAGCGAGTGCTGACGCCGGGAGCGCAAGTACGAGTCTCCGATGTGTTTCCC
GGCGCGGGAGAGGCCCTGCTGGAAGCGGCACGGGAGAACGGGCTCGAGGGCATCATCGCCAAGCATCCGCGGAGCTGCTA
CGAATCCAGGCGAAGCCGCGAGTGGCTAAAGATCAAGATTGTCACCGAGCAGGAATTCGTGATCGGCGGGTTCACGGAAC
CCCAAGGCGACCGGCAGTACTTCGGCGCGCTTGTGCTGGGGGTGCAAAAGGCGGGCGCCCTGCGCTGGGTCGGCAATGTG
GGCACGGGCTTCGATCAAAAGCTGCTGGCGAGCCTATACGCGCGGCTCGAGCCACTGATCACCACTAAGTGCCCGTTCGT
CGAGCGGCCCAAGCCGGATCGAGGGATGACGTGGGTAAGGCCGGAGCTGGTATGCCAGGTGAAATACGGCAACTGGACCC
CGGACGACCGGCTGCGCGCACCGGTCTTCATCGGGCTGCGCAACGACAAGCCCGTGGTGGAGGTGGAGAAAGAGACGACG
GGTGAACTGCTTCCGAAGAGCAAGGAGGCGACGCTACCGATCGACGGGCGCACGCTCAAGTTCACGAATCTCTCTAAGCT
GTATTACCCCGACGATGGGGTCAGCAAGCGGGACGTGATCAACTACTACGACTCGGTGGCGGATTTGATTCTGCCGCATC
TGAGAGACCGGCCGCTTTCTCTGAAGCGATATCCGAACGGCATCAAGGAGGATTTTTTCTTCCAAAAGAATACGCCGGAG
ACGTATCCTGCGTGGATGCGGACGGAGCTGATCGACAGCGACCACGCGGGGGCGATCAACTACGTGTTCGCGGATGACCG
GGCAAGCCTGCTGTACCTGGTGAATCTGGGATGCATCGACCAGAATCCGTGGATCAGCCGGTCGGGATCGCTGGACAATC
CGGATTTCGTTCTAATCGACCTGGATCCGCAAGAGTGCGCATACGATTTGATTGTGGAAGCGGCGGTGATGGTGAAGGAA
ATTCTAGACCGGATCGGGCTGAAGGGTTATCCGAAGACAACAGGCGGGGACGGGATGCACGTGTACATTCCGGTGGAAGC
GGTGTACAGCTATGAGGAGACGCGGATCTTCGCGGAACTGATCGCGCGGCTGGTGACGCAGCGGAAGCCGCAGATGTACA
CAACGCCGCGCTCGGTGAGCAAGCGACAGAAGAACCGGGTGTATTTCGATTACTTGCAGAACGGGAAATCGAAGACGATC
GCGGCGCCGTATGTGCTGCGGGCGTACCCTGGGGCCCCGGTGGCAACTCCGCTGGAGTGGAGCGAGGTTAAGCCCGGGCT
GGACCCGAAGCAGTTTCACATCGGGAATGCACGGGAGCGGTTCCGGAAGAAGGGCGATCTGTTCCGTGGAGTGTTGGATG
CGCCGCAGAATCTTTACGATGCGCTGGGCAAGCTGGAGAAGCTTTTCCGGTAA

Upstream 100 bases:

>100_bases
GTCCGGCAAAGCGCGCGGGGAACACGGCGGCGAGCACGGCTGCCAAAGCTGCGCCGGCAAAAAAAAAACTGAAATCGAGC
TCGGGACAATAAAGGGCGCG

Downstream 100 bases:

>100_bases
CCTACTGCTCGGTGGTAAGGAAGATGACGACGCCATTGCCGCGGAATAGCAGGTCGGCGGAGGCCTTGTGGGCGGCGTCG
GCTTTGCGGGGAACGACACG

Product: ATP dependent DNA ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 630; Mature: 629

Protein sequence:

>630_residues
MPAEMPASIEPMKATIAERVPRGDEWLFEIKWDGVRAVAFLDNEEVRLQARSGLRCERQYPELAVLPHHVAAARAILDGE
IAVLDAKGVSQFHLIQPRIANSDPNTIAHLVRSTPVVYFAFDLLYLDGYDLRNVDLAKRRELLERVLTPGAQVRVSDVFP
GAGEALLEAARENGLEGIIAKHPRSCYESRRSREWLKIKIVTEQEFVIGGFTEPQGDRQYFGALVLGVQKAGALRWVGNV
GTGFDQKLLASLYARLEPLITTKCPFVERPKPDRGMTWVRPELVCQVKYGNWTPDDRLRAPVFIGLRNDKPVVEVEKETT
GELLPKSKEATLPIDGRTLKFTNLSKLYYPDDGVSKRDVINYYDSVADLILPHLRDRPLSLKRYPNGIKEDFFFQKNTPE
TYPAWMRTELIDSDHAGAINYVFADDRASLLYLVNLGCIDQNPWISRSGSLDNPDFVLIDLDPQECAYDLIVEAAVMVKE
ILDRIGLKGYPKTTGGDGMHVYIPVEAVYSYEETRIFAELIARLVTQRKPQMYTTPRSVSKRQKNRVYFDYLQNGKSKTI
AAPYVLRAYPGAPVATPLEWSEVKPGLDPKQFHIGNARERFRKKGDLFRGVLDAPQNLYDALGKLEKLFR

Sequences:

>Translated_630_residues
MPAEMPASIEPMKATIAERVPRGDEWLFEIKWDGVRAVAFLDNEEVRLQARSGLRCERQYPELAVLPHHVAAARAILDGE
IAVLDAKGVSQFHLIQPRIANSDPNTIAHLVRSTPVVYFAFDLLYLDGYDLRNVDLAKRRELLERVLTPGAQVRVSDVFP
GAGEALLEAARENGLEGIIAKHPRSCYESRRSREWLKIKIVTEQEFVIGGFTEPQGDRQYFGALVLGVQKAGALRWVGNV
GTGFDQKLLASLYARLEPLITTKCPFVERPKPDRGMTWVRPELVCQVKYGNWTPDDRLRAPVFIGLRNDKPVVEVEKETT
GELLPKSKEATLPIDGRTLKFTNLSKLYYPDDGVSKRDVINYYDSVADLILPHLRDRPLSLKRYPNGIKEDFFFQKNTPE
TYPAWMRTELIDSDHAGAINYVFADDRASLLYLVNLGCIDQNPWISRSGSLDNPDFVLIDLDPQECAYDLIVEAAVMVKE
ILDRIGLKGYPKTTGGDGMHVYIPVEAVYSYEETRIFAELIARLVTQRKPQMYTTPRSVSKRQKNRVYFDYLQNGKSKTI
AAPYVLRAYPGAPVATPLEWSEVKPGLDPKQFHIGNARERFRKKGDLFRGVLDAPQNLYDALGKLEKLFR
>Mature_629_residues
PAEMPASIEPMKATIAERVPRGDEWLFEIKWDGVRAVAFLDNEEVRLQARSGLRCERQYPELAVLPHHVAAARAILDGEI
AVLDAKGVSQFHLIQPRIANSDPNTIAHLVRSTPVVYFAFDLLYLDGYDLRNVDLAKRRELLERVLTPGAQVRVSDVFPG
AGEALLEAARENGLEGIIAKHPRSCYESRRSREWLKIKIVTEQEFVIGGFTEPQGDRQYFGALVLGVQKAGALRWVGNVG
TGFDQKLLASLYARLEPLITTKCPFVERPKPDRGMTWVRPELVCQVKYGNWTPDDRLRAPVFIGLRNDKPVVEVEKETTG
ELLPKSKEATLPIDGRTLKFTNLSKLYYPDDGVSKRDVINYYDSVADLILPHLRDRPLSLKRYPNGIKEDFFFQKNTPET
YPAWMRTELIDSDHAGAINYVFADDRASLLYLVNLGCIDQNPWISRSGSLDNPDFVLIDLDPQECAYDLIVEAAVMVKEI
LDRIGLKGYPKTTGGDGMHVYIPVEAVYSYEETRIFAELIARLVTQRKPQMYTTPRSVSKRQKNRVYFDYLQNGKSKTIA
APYVLRAYPGAPVATPLEWSEVKPGLDPKQFHIGNARERFRKKGDLFRGVLDAPQNLYDALGKLEKLFR

Specific function: Probably involved in the repair of DNA double-strand breaks by non-homologous-end joining (NHEJ) during spore germination [H]

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012310
- InterPro:   IPR014146
- InterPro:   IPR014145
- InterPro:   IPR014143 [H]

Pfam domain/function: PF01068 DNA_ligase_A_M [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 71354; Mature: 71222

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: PS00697 DNA_LIGASE_A1 ; PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAEMPASIEPMKATIAERVPRGDEWLFEIKWDGVRAVAFLDNEEVRLQARSGLRCERQY
CCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCEEEEEEECCCCEEEEECCCCEEHHCC
PELAVLPHHVAAARAILDGEIAVLDAKGVSQFHLIQPRIANSDPNTIAHLVRSTPVVYFA
CCEEECCHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHCCEEEEE
FDLLYLDGYDLRNVDLAKRRELLERVLTPGAQVRVSDVFPGAGEALLEAARENGLEGIIA
EEHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCCCHHH
KHPRSCYESRRSREWLKIKIVTEQEFVIGGFTEPQGDRQYFGALVLGVQKAGALRWVGNV
CCCHHHHHHHCCCCEEEEEEEECCEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEECCC
GTGFDQKLLASLYARLEPLITTKCPFVERPKPDRGMTWVRPELVCQVKYGNWTPDDRLRA
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCEEEEEEECCCCCCCCCCCC
PVFIGLRNDKPVVEVEKETTGELLPKSKEATLPIDGRTLKFTNLSKLYYPDDGVSKRDVI
CEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEECCCCCCCHHHHH
NYYDSVADLILPHLRDRPLSLKRYPNGIKEDFFFQKNTPETYPAWMRTELIDSDHAGAIN
HHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHEEECCCCCCCCHHHHHHHCCCCCCCEEE
YVFADDRASLLYLVNLGCIDQNPWISRSGSLDNPDFVLIDLDPQECAYDLIVEAAVMVKE
EEEECCCCEEEEEEEECEECCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHH
ILDRIGLKGYPKTTGGDGMHVYIPVEAVYSYEETRIFAELIARLVTQRKPQMYTTPRSVS
HHHHCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHH
KRQKNRVYFDYLQNGKSKTIAAPYVLRAYPGAPVATPLEWSEVKPGLDPKQFHIGNARER
HHHHCCEEEEHHHCCCCCEEECCEEEEECCCCCCCCCCCHHHCCCCCCCCCEECCCHHHH
FRKKGDLFRGVLDAPQNLYDALGKLEKLFR
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
PAEMPASIEPMKATIAERVPRGDEWLFEIKWDGVRAVAFLDNEEVRLQARSGLRCERQY
CCCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCEEEEEEECCCCEEEEECCCCEEHHCC
PELAVLPHHVAAARAILDGEIAVLDAKGVSQFHLIQPRIANSDPNTIAHLVRSTPVVYFA
CCEEECCHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHCCEEEEE
FDLLYLDGYDLRNVDLAKRRELLERVLTPGAQVRVSDVFPGAGEALLEAARENGLEGIIA
EEHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCCCHHH
KHPRSCYESRRSREWLKIKIVTEQEFVIGGFTEPQGDRQYFGALVLGVQKAGALRWVGNV
CCCHHHHHHHCCCCEEEEEEEECCEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEECCC
GTGFDQKLLASLYARLEPLITTKCPFVERPKPDRGMTWVRPELVCQVKYGNWTPDDRLRA
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCEEEEEEECCCCCCCCCCCC
PVFIGLRNDKPVVEVEKETTGELLPKSKEATLPIDGRTLKFTNLSKLYYPDDGVSKRDVI
CEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEECCCCCCCHHHHH
NYYDSVADLILPHLRDRPLSLKRYPNGIKEDFFFQKNTPETYPAWMRTELIDSDHAGAIN
HHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHEEECCCCCCCCHHHHHHHCCCCCCCEEE
YVFADDRASLLYLVNLGCIDQNPWISRSGSLDNPDFVLIDLDPQECAYDLIVEAAVMVKE
EEEECCCCEEEEEEEECEECCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHH
ILDRIGLKGYPKTTGGDGMHVYIPVEAVYSYEETRIFAELIARLVTQRKPQMYTTPRSVS
HHHHCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHH
KRQKNRVYFDYLQNGKSKTIAAPYVLRAYPGAPVATPLEWSEVKPGLDPKQFHIGNARER
HHHHCCEEEEHHHCCCCCEEECCEEEEECCCCCCCCCCCHHHCCCCCCCCCEECCCHHHH
FRKKGDLFRGVLDAPQNLYDALGKLEKLFR
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]