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The map label for this gene is dagK [H]

Identifier: 116626793

GI number: 116626793

Start: 9748489

End: 9749349

Strand: Direct

Name: dagK [H]

Synonym: Acid_7766

Alternate gene names: 116626793

Gene position: 9748489-9749349 (Clockwise)

Preceding gene: 116626791

Following gene: 116626794

Centisome position: 97.82

GC content: 64.23

Gene sequence:

>861_bases
TTGATCGAGCGCGCCGGGCGCATCCTTACACAACAAGGTCATAATTTGACGGTGGCGCCGACCACCGGGCCGCGGGTCGC
GGGCGAGATCGCGCGCGAACACATCCAACACGGTGCGGACCTGATCGTGGTGGCGGGCGGCGACGGCACCATCAACGAAG
CCGCCGAAGGCATGCTCGGCACTGATGTCCCACTCGCGATTCTGCCCGCCGGTACCGCCAACGTGCTTGCCATGGAAACC
AAACTGGGCGGCAATCTGGAGCGCGTGGCCGCTCGCCTCGACGGGCTCAAGCCGCGCCGCATTTCGGTGGGCCGCGTCAC
CTGCGACGACGGCAAGCTCTCGCGCCACTTTCTGCTGATGGCGGGCATCGGGCTGGATGCCCACGTGGTCTATAACATCA
ACGCGGGCCTGAAGGCCAAGACCGGCAAGTTCGCCTACTGGGTGGCCGGCTGGAGCCTGCTCGGCAAGCGCCTGGCGGAA
TTCGACGTCGAGCTCGCCGGCCAGCGCCGGCGCTGCTCCTTCGCCCTCTTGAGCAAGGTGCGAAACTACGGCGGCGATTT
CGAAATCGCCCGCAGCGTCACCCTGATGGACGATGAATTCGAGGTCGTCCTCTTCGAAGGACCCAACACGACTGGCTACG
TGAAGTACTTCGCCGGCATGGCGCTCAACAAACTCGTGGGGATGAGCGGCGTGACAGTCCTGCGCGCCAGCGATATTCGC
GTGTCGAAGCCTGCCGACCGCCGTGCGTATATCCAGATCGATGGCGAATTCCTGGGGCACTTGCCGGCGGAGTTTAAGAT
CGTGCGCGACTCCCTGACCGTTCTGGTTCCCGCGGAGTACGGTTCCGTCAAAAAGTCCTGA

Upstream 100 bases:

>100_bases
AATCTAACGAGGACCGGGAGCAAACACCATCACCAGCTACAGGAAGACCGTACTGATCTTTAACCCCCGTGCGGGTAAGG
TCTTACGGACCGGAGGCGCA

Downstream 100 bases:

>100_bases
GGAACTGTCGGTAGGCGCCGCTCTGGAAGGTGGTCCACGGCTGGAAGCCGCGCTCCGTGTAGAGCTGATAGGCGAAATCG
ATATTGGCCTTGCAATCCAG

Product: diacylglycerol kinase catalytic subunit

Products: NA

Alternate protein names: DAG kinase; DAGK [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MIERAGRILTQQGHNLTVAPTTGPRVAGEIAREHIQHGADLIVVAGGDGTINEAAEGMLGTDVPLAILPAGTANVLAMET
KLGGNLERVAARLDGLKPRRISVGRVTCDDGKLSRHFLLMAGIGLDAHVVYNINAGLKAKTGKFAYWVAGWSLLGKRLAE
FDVELAGQRRRCSFALLSKVRNYGGDFEIARSVTLMDDEFEVVLFEGPNTTGYVKYFAGMALNKLVGMSGVTVLRASDIR
VSKPADRRAYIQIDGEFLGHLPAEFKIVRDSLTVLVPAEYGSVKKS

Sequences:

>Translated_286_residues
MIERAGRILTQQGHNLTVAPTTGPRVAGEIAREHIQHGADLIVVAGGDGTINEAAEGMLGTDVPLAILPAGTANVLAMET
KLGGNLERVAARLDGLKPRRISVGRVTCDDGKLSRHFLLMAGIGLDAHVVYNINAGLKAKTGKFAYWVAGWSLLGKRLAE
FDVELAGQRRRCSFALLSKVRNYGGDFEIARSVTLMDDEFEVVLFEGPNTTGYVKYFAGMALNKLVGMSGVTVLRASDIR
VSKPADRRAYIQIDGEFLGHLPAEFKIVRDSLTVLVPAEYGSVKKS
>Mature_286_residues
MIERAGRILTQQGHNLTVAPTTGPRVAGEIAREHIQHGADLIVVAGGDGTINEAAEGMLGTDVPLAILPAGTANVLAMET
KLGGNLERVAARLDGLKPRRISVGRVTCDDGKLSRHFLLMAGIGLDAHVVYNINAGLKAKTGKFAYWVAGWSLLGKRLAE
FDVELAGQRRRCSFALLSKVRNYGGDFEIARSVTLMDDEFEVVLFEGPNTTGYVKYFAGMALNKLVGMSGVTVLRASDIR
VSKPADRRAYIQIDGEFLGHLPAEFKIVRDSLTVLVPAEYGSVKKS

Specific function: Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid. Is involved in the biosynthesis of phosphatidylinositol mannosides (PIMs), probably via a role in the biosynthesis of phosphatidylinositol (PI), a PIM precursor, which is derive

COG id: COG1597

COG function: function code IR; Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase

Gene ontology:

Cell location: Secreted, cell wall (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DAGKc domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005218
- InterPro:   IPR001206 [H]

Pfam domain/function: PF00781 DAGK_cat [H]

EC number: =2.7.1.107 [H]

Molecular weight: Translated: 30791; Mature: 30791

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIERAGRILTQQGHNLTVAPTTGPRVAGEIAREHIQHGADLIVVAGGDGTINEAAEGMLG
CCCCCCCHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCCC
TDVPLAILPAGTANVLAMETKLGGNLERVAARLDGLKPRRISVGRVTCDDGKLSRHFLLM
CCCCEEEECCCCCEEEEEEECCCCCHHHHHHHHCCCCCCEEEEEEEEECCCCCCEEEEEE
AGIGLDAHVVYNINAGLKAKTGKFAYWVAGWSLLGKRLAEFDVELAGQRRRCSFALLSKV
EECCCCEEEEEEECCCCEECCCCEEEEEHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHH
RNYGGDFEIARSVTLMDDEFEVVLFEGPNTTGYVKYFAGMALNKLVGMSGVTVLRASDIR
HHCCCCEEEEEEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCEE
VSKPADRRAYIQIDGEFLGHLPAEFKIVRDSLTVLVPAEYGSVKKS
ECCCCCCEEEEEECCHHCCCCCCCEEEEECCEEEEEECCCCCCCCC
>Mature Secondary Structure
MIERAGRILTQQGHNLTVAPTTGPRVAGEIAREHIQHGADLIVVAGGDGTINEAAEGMLG
CCCCCCCHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCCC
TDVPLAILPAGTANVLAMETKLGGNLERVAARLDGLKPRRISVGRVTCDDGKLSRHFLLM
CCCCEEEECCCCCEEEEEEECCCCCHHHHHHHHCCCCCCEEEEEEEEECCCCCCEEEEEE
AGIGLDAHVVYNINAGLKAKTGKFAYWVAGWSLLGKRLAEFDVELAGQRRRCSFALLSKV
EECCCCEEEEEEECCCCEECCCCEEEEEHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHH
RNYGGDFEIARSVTLMDDEFEVVLFEGPNTTGYVKYFAGMALNKLVGMSGVTVLRASDIR
HHCCCCEEEEEEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCEE
VSKPADRRAYIQIDGEFLGHLPAEFKIVRDSLTVLVPAEYGSVKKS
ECCCCCCEEEEEECCHHCCCCCCCEEEEECCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]