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The map label for this gene is xylS [H]

Identifier: 116626640

GI number: 116626640

Start: 9538891

End: 9541161

Strand: Direct

Name: xylS [H]

Synonym: Acid_7605

Alternate gene names: 116626640

Gene position: 9538891-9541161 (Clockwise)

Preceding gene: 116626639

Following gene: 116626641

Centisome position: 95.72

GC content: 61.73

Gene sequence:

>2271_bases
ATGAAGGACACAATCAGCCGCAGACATGCTCTCCGAAGCGCCGCGACTGCGGGCGCCGGAGCTCTGCTGCTACCGTCACT
GGCGCTGGCACAAGAAAGAACGCTGGAACTGACCGGCAAGCCGGTGGAAGTGACTATCACGCCGGTCACCGCACAGACCG
TGCGTATCACCATCCAGCCTGTCGAGAACGGCCAGCTCAAGCCTGGGCCGAAAGACGGCGCACTGGTGAAAGAGGATTTC
GGTAAAGCCGCCGCCAACGTTCGGGCCGTATCCGGATCTCTCACGGTGAAGTGCGGTGACCTGAATGTGAAAGTGAGTGT
CGACCCCATTGCCATCCGCGTCGAAGGCCAGGATAGGCGCGTGATTCAGGAATTGCGGGTCGATGGGAAAAGCGGCAACC
TGACCTTCCGAATCGGCGACTCTCCGGTCCTCGGGCTAGGGCAGGGCGGTCCGCAGTTCGATAAGCGGGGCAATCTCGAC
CGCATGGGAAGCGGCCAAGGCGGCTACCGGCTGGCAACCCATGGCGCCAAAGTTCCGGTGCAACTGCTCCTCGGAACTGC
GGGATGGGCGATGTACGTGCACCAGCCCCTTGGCTCCTTCGACCTCACTGGCAAAGAGGGTCTCTTCTTCCCTCCCGGCG
TCGACAACGCACTGCCGCTCGATCTATTCGTCATTGGGGCCAAAGATCCGACTGCCGTGATGCGCGAGTACGCTGCGATC
ACGGGGTTCCCTGAGATGCCTCCCTTGTGGTCGTTCGGCTATCAGCAGTCGCACCGCACTCTGGATTCCCCGGAGCAGAC
GATCCAGGAAGCCAAGATCTTCCGCGAGAAAAAACTGCCGTGCGACATGATGATCTATCTTGGGACGGACTTCTGCCTCA
ACGGCTGGAACACGCACAACGGCGAGTTCACGTGGAACGAAAAGGCGTTCCCGGATCCGAAGCAAATGGTGCAACAACTC
CACGACCTGAATTTCAAGGTGGTGGTGCACACCGTGGTGGAAGGCCACACGTTCAGTGGAACCGTGACAGACCTGTGCAC
CGCATCGCCGATTCCCAGCGGGCGGATGGCCGATGGACGGACCTGGCCTCCGGACCGCCAGGTACCGTGCTACTGGCCCG
CCCACAAGCCGCTGCTCGACATCGGGATCGATGGCTGGTGGCCGGACCAGGGCGACGGCTTCGATCCCCCGTCGCGCCTG
CTGCGTAATCGCATGTATTTCGAAGGGCACCAGATGTACCGGCCCAACGAGCGGGTCTACGCCCTGCACCGCAACGCCTA
CGCAGGAATGGCGCGCTACGCCGCCTTCCTGTGGTCGGGCGACGTGCGATCCACTTGGGAGACGTTAAGGACTCACGTCG
CGGTCGGAATCAACGCGGGGCTCAGCGGCATTCCGTACTGGGGCAGCGATATCGGCGGGTTTGTCCCGACGCAGGAATTC
ACCGGTGAACTCTACGCGCGGTGGTTCCAGTTCGCGGCATTCAATCCTTTGTTCCGGTCTCATGGCAGGGAGTGGCGGCT
GCGCCTGCCGTGGGGCTGGAATCGCGGCGAAATCGGCGGCTTCCGTGAGACTCCGGCCTACAATCCAGACCCGGCGGAAT
TGCATAATGCGGCCATCGAACCGGTGTGCAAGAAATACCTCGAATTACGCTACCAGATGATGCCGTACCTGTATTCCGCG
GTCCGGGAGACTTGCGAGACGGGTATGCCCATCATCCGCGCGATGTGGCTTCACTACCCAGGCGACGCCAAGGCCGTCGG
GATGGGCGATCAATACCTGTACGGCCGTGACATTCTGGTGGCGCCGGTGTTCGAGAAGGGCGCGACTTCGCGCGCGGTGT
ATCTGCCGCGCGGCACATGGTACGACTTCTGGACGCGGGAAAAGCTGGATGGCGGACGCGAGATCTCGCGCAAGGTGGAT
CTGGAGACGATTCCGCTGTACGTGCGCGCCGGGGCCATTGTTCCCATGGGTCCGGTCAAGCAGTATACGTGGGAAAAAGT
GGATGGGCCAATGACGGTTTGGGTTTATCCCGGAGCAGATGGGACATTCTCCTGGTACGAGGATGACGGCGCTTCATTCA
ACTTCCGCAACGGCGAGCTTATGCGCGTCAATCTGGCGTGGAGCCACAGCCAGCGGCGGTTGACGATGCGGTTGGCCAAC
GGTTCGAAAATGCTCACGCCCCAGAGGCGCGGCATCGTGGTCCGCGTTGCCGGCGAGTCGGTCTCCCGGAACGCAACCTT
TGATGGCAGACCGGTAGAGATTCAGCTCTAG

Upstream 100 bases:

>100_bases
CCAAGGGCGACGGCGCGGGGAATCCCAGAACACGTGACTGTTCGACCAGGAAGTCTCTCGGGGGGAAGAAAGGCAAGTCG
ACAATGTCGATGAACGAGCC

Downstream 100 bases:

>100_bases
GCCGGCCTACTTGGGTAAGGGGGCGTCTTGCTGTAGTGTGTGGCGGGGCGCAGAGCTTTGCTGATCACGGCAAAGCACGA
CGAGGGTAGCGATTGCGTTT

Product: glycoside hydrolase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 756; Mature: 756

Protein sequence:

>756_residues
MKDTISRRHALRSAATAGAGALLLPSLALAQERTLELTGKPVEVTITPVTAQTVRITIQPVENGQLKPGPKDGALVKEDF
GKAAANVRAVSGSLTVKCGDLNVKVSVDPIAIRVEGQDRRVIQELRVDGKSGNLTFRIGDSPVLGLGQGGPQFDKRGNLD
RMGSGQGGYRLATHGAKVPVQLLLGTAGWAMYVHQPLGSFDLTGKEGLFFPPGVDNALPLDLFVIGAKDPTAVMREYAAI
TGFPEMPPLWSFGYQQSHRTLDSPEQTIQEAKIFREKKLPCDMMIYLGTDFCLNGWNTHNGEFTWNEKAFPDPKQMVQQL
HDLNFKVVVHTVVEGHTFSGTVTDLCTASPIPSGRMADGRTWPPDRQVPCYWPAHKPLLDIGIDGWWPDQGDGFDPPSRL
LRNRMYFEGHQMYRPNERVYALHRNAYAGMARYAAFLWSGDVRSTWETLRTHVAVGINAGLSGIPYWGSDIGGFVPTQEF
TGELYARWFQFAAFNPLFRSHGREWRLRLPWGWNRGEIGGFRETPAYNPDPAELHNAAIEPVCKKYLELRYQMMPYLYSA
VRETCETGMPIIRAMWLHYPGDAKAVGMGDQYLYGRDILVAPVFEKGATSRAVYLPRGTWYDFWTREKLDGGREISRKVD
LETIPLYVRAGAIVPMGPVKQYTWEKVDGPMTVWVYPGADGTFSWYEDDGASFNFRNGELMRVNLAWSHSQRRLTMRLAN
GSKMLTPQRRGIVVRVAGESVSRNATFDGRPVEIQL

Sequences:

>Translated_756_residues
MKDTISRRHALRSAATAGAGALLLPSLALAQERTLELTGKPVEVTITPVTAQTVRITIQPVENGQLKPGPKDGALVKEDF
GKAAANVRAVSGSLTVKCGDLNVKVSVDPIAIRVEGQDRRVIQELRVDGKSGNLTFRIGDSPVLGLGQGGPQFDKRGNLD
RMGSGQGGYRLATHGAKVPVQLLLGTAGWAMYVHQPLGSFDLTGKEGLFFPPGVDNALPLDLFVIGAKDPTAVMREYAAI
TGFPEMPPLWSFGYQQSHRTLDSPEQTIQEAKIFREKKLPCDMMIYLGTDFCLNGWNTHNGEFTWNEKAFPDPKQMVQQL
HDLNFKVVVHTVVEGHTFSGTVTDLCTASPIPSGRMADGRTWPPDRQVPCYWPAHKPLLDIGIDGWWPDQGDGFDPPSRL
LRNRMYFEGHQMYRPNERVYALHRNAYAGMARYAAFLWSGDVRSTWETLRTHVAVGINAGLSGIPYWGSDIGGFVPTQEF
TGELYARWFQFAAFNPLFRSHGREWRLRLPWGWNRGEIGGFRETPAYNPDPAELHNAAIEPVCKKYLELRYQMMPYLYSA
VRETCETGMPIIRAMWLHYPGDAKAVGMGDQYLYGRDILVAPVFEKGATSRAVYLPRGTWYDFWTREKLDGGREISRKVD
LETIPLYVRAGAIVPMGPVKQYTWEKVDGPMTVWVYPGADGTFSWYEDDGASFNFRNGELMRVNLAWSHSQRRLTMRLAN
GSKMLTPQRRGIVVRVAGESVSRNATFDGRPVEIQL
>Mature_756_residues
MKDTISRRHALRSAATAGAGALLLPSLALAQERTLELTGKPVEVTITPVTAQTVRITIQPVENGQLKPGPKDGALVKEDF
GKAAANVRAVSGSLTVKCGDLNVKVSVDPIAIRVEGQDRRVIQELRVDGKSGNLTFRIGDSPVLGLGQGGPQFDKRGNLD
RMGSGQGGYRLATHGAKVPVQLLLGTAGWAMYVHQPLGSFDLTGKEGLFFPPGVDNALPLDLFVIGAKDPTAVMREYAAI
TGFPEMPPLWSFGYQQSHRTLDSPEQTIQEAKIFREKKLPCDMMIYLGTDFCLNGWNTHNGEFTWNEKAFPDPKQMVQQL
HDLNFKVVVHTVVEGHTFSGTVTDLCTASPIPSGRMADGRTWPPDRQVPCYWPAHKPLLDIGIDGWWPDQGDGFDPPSRL
LRNRMYFEGHQMYRPNERVYALHRNAYAGMARYAAFLWSGDVRSTWETLRTHVAVGINAGLSGIPYWGSDIGGFVPTQEF
TGELYARWFQFAAFNPLFRSHGREWRLRLPWGWNRGEIGGFRETPAYNPDPAELHNAAIEPVCKKYLELRYQMMPYLYSA
VRETCETGMPIIRAMWLHYPGDAKAVGMGDQYLYGRDILVAPVFEKGATSRAVYLPRGTWYDFWTREKLDGGREISRKVD
LETIPLYVRAGAIVPMGPVKQYTWEKVDGPMTVWVYPGADGTFSWYEDDGASFNFRNGELMRVNLAWSHSQRRLTMRLAN
GSKMLTPQRRGIVVRVAGESVSRNATFDGRPVEIQL

Specific function: Catalyzes the liberation of alpha-xylose from the non- reducing terminal glucose of xyloglucan oligosaccharides. Has high hydrolytic activity on the disaccharide isoprimeverose. Follows a retaining mechanism of substrate hydrolysis [H]

COG id: COG1501

COG function: function code G; Alpha-glucosidases, family 31 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 31 family [H]

Homologues:

Organism=Homo sapiens, GI88900491, Length=529, Percent_Identity=27.7882797731569, Blast_Score=181, Evalue=3e-45,
Organism=Homo sapiens, GI38202257, Length=529, Percent_Identity=27.7882797731569, Blast_Score=181, Evalue=3e-45,
Organism=Homo sapiens, GI66346737, Length=531, Percent_Identity=26.3653483992467, Blast_Score=166, Evalue=1e-40,
Organism=Homo sapiens, GI157364974, Length=622, Percent_Identity=24.7588424437299, Blast_Score=133, Evalue=6e-31,
Organism=Homo sapiens, GI119393895, Length=577, Percent_Identity=24.263431542461, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI119393893, Length=577, Percent_Identity=24.263431542461, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI119393891, Length=577, Percent_Identity=24.263431542461, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI221316699, Length=679, Percent_Identity=23.4167893961708, Blast_Score=123, Evalue=6e-28,
Organism=Homo sapiens, GI310115361, Length=240, Percent_Identity=28.75, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI153791946, Length=370, Percent_Identity=25.6756756756757, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI2367256, Length=664, Percent_Identity=25.3012048192771, Blast_Score=163, Evalue=5e-41,
Organism=Escherichia coli, GI2367323, Length=303, Percent_Identity=28.0528052805281, Blast_Score=108, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71991189, Length=539, Percent_Identity=24.860853432282, Blast_Score=163, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17560800, Length=567, Percent_Identity=22.9276895943563, Blast_Score=142, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI17560798, Length=567, Percent_Identity=22.9276895943563, Blast_Score=142, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI32563849, Length=283, Percent_Identity=31.8021201413428, Blast_Score=122, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI71985706, Length=243, Percent_Identity=30.0411522633745, Blast_Score=108, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6319706, Length=544, Percent_Identity=23.1617647058824, Blast_Score=131, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24643749, Length=551, Percent_Identity=27.2232304900181, Blast_Score=162, Evalue=6e-40,
Organism=Drosophila melanogaster, GI24643753, Length=551, Percent_Identity=27.2232304900181, Blast_Score=162, Evalue=6e-40,
Organism=Drosophila melanogaster, GI24643751, Length=551, Percent_Identity=27.2232304900181, Blast_Score=162, Evalue=6e-40,
Organism=Drosophila melanogaster, GI24643746, Length=551, Percent_Identity=27.2232304900181, Blast_Score=162, Evalue=6e-40,
Organism=Drosophila melanogaster, GI21357605, Length=551, Percent_Identity=27.2232304900181, Blast_Score=162, Evalue=6e-40,
Organism=Drosophila melanogaster, GI24650054, Length=398, Percent_Identity=23.1155778894472, Blast_Score=72, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011013
- InterPro:   IPR000322
- InterPro:   IPR017853 [H]

Pfam domain/function: PF01055 Glyco_hydro_31 [H]

EC number: NA

Molecular weight: Translated: 84433; Mature: 84433

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDTISRRHALRSAATAGAGALLLPSLALAQERTLELTGKPVEVTITPVTAQTVRITIQP
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEECCCEEEEEEEEEEEEEEEEEEEE
VENGQLKPGPKDGALVKEDFGKAAANVRAVSGSLTVKCGDLNVKVSVDPIAIRVEGQDRR
CCCCCCCCCCCCCCEEHHHHHHHHCCEEEECCEEEEEECCEEEEEEECEEEEEECCCHHH
VIQELRVDGKSGNLTFRIGDSPVLGLGQGGPQFDKRGNLDRMGSGQGGYRLATHGAKVPV
HHHHHHCCCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEE
QLLLGTAGWAMYVHQPLGSFDLTGKEGLFFPPGVDNALPLDLFVIGAKDPTAVMREYAAI
EEEEECCCEEEEEECCCCCCCCCCCCCEECCCCCCCCCCEEEEEECCCCHHHHHHHHHHH
TGFPEMPPLWSFGYQQSHRTLDSPEQTIQEAKIFREKKLPCDMMIYLGTDFCLNGWNTHN
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCEEECCCCCCC
GEFTWNEKAFPDPKQMVQQLHDLNFKVVVHTVVEGHTFSGTVTDLCTASPIPSGRMADGR
CEEEECCCCCCCHHHHHHHHHCCCEEEEEEEEECCCCCCCCHHHHHCCCCCCCCCCCCCC
TWPPDRQVPCYWPAHKPLLDIGIDGWWPDQGDGFDPPSRLLRNRMYFEGHQMYRPNERVY
CCCCCCCCCEECCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHEECCCCEECCCCEEE
ALHRNAYAGMARYAAFLWSGDVRSTWETLRTHVAVGINAGLSGIPYWGSDIGGFVPTQEF
EEECCCHHHHHHHHHHHCCCCHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCCCHHH
TGELYARWFQFAAFNPLFRSHGREWRLRLPWGWNRGEIGGFRETPAYNPDPAELHNAAIE
HHHHHHHHHHHHHCCHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
PVCKKYLELRYQMMPYLYSAVRETCETGMPIIRAMWLHYPGDAKAVGMGDQYLYGRDILV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHEECCCCCCEECCCCCEEECCCEEE
APVFEKGATSRAVYLPRGTWYDFWTREKLDGGREISRKVDLETIPLYVRAGAIVPMGPVK
EECCCCCCCCCEEEECCCCEECCCCHHHCCCCHHHHHCCCCEEEEEEEECCCCCCCCCCC
QYTWEKVDGPMTVWVYPGADGTFSWYEDDGASFNFRNGELMRVNLAWSHSQRRLTMRLAN
CCCHHHCCCCEEEEEECCCCCCEEEECCCCCEEEECCCCEEEEEEEECCCCEEEEEEEEC
GSKMLTPQRRGIVVRVAGESVSRNATFDGRPVEIQL
CCEECCCCCCCEEEEECCCCCCCCCCCCCCEEEEEC
>Mature Secondary Structure
MKDTISRRHALRSAATAGAGALLLPSLALAQERTLELTGKPVEVTITPVTAQTVRITIQP
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEECCCEEEEEEEEEEEEEEEEEEEE
VENGQLKPGPKDGALVKEDFGKAAANVRAVSGSLTVKCGDLNVKVSVDPIAIRVEGQDRR
CCCCCCCCCCCCCCEEHHHHHHHHCCEEEECCEEEEEECCEEEEEEECEEEEEECCCHHH
VIQELRVDGKSGNLTFRIGDSPVLGLGQGGPQFDKRGNLDRMGSGQGGYRLATHGAKVPV
HHHHHHCCCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEE
QLLLGTAGWAMYVHQPLGSFDLTGKEGLFFPPGVDNALPLDLFVIGAKDPTAVMREYAAI
EEEEECCCEEEEEECCCCCCCCCCCCCEECCCCCCCCCCEEEEEECCCCHHHHHHHHHHH
TGFPEMPPLWSFGYQQSHRTLDSPEQTIQEAKIFREKKLPCDMMIYLGTDFCLNGWNTHN
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCEEECCCCCCC
GEFTWNEKAFPDPKQMVQQLHDLNFKVVVHTVVEGHTFSGTVTDLCTASPIPSGRMADGR
CEEEECCCCCCCHHHHHHHHHCCCEEEEEEEEECCCCCCCCHHHHHCCCCCCCCCCCCCC
TWPPDRQVPCYWPAHKPLLDIGIDGWWPDQGDGFDPPSRLLRNRMYFEGHQMYRPNERVY
CCCCCCCCCEECCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHEECCCCEECCCCEEE
ALHRNAYAGMARYAAFLWSGDVRSTWETLRTHVAVGINAGLSGIPYWGSDIGGFVPTQEF
EEECCCHHHHHHHHHHHCCCCHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCCCHHH
TGELYARWFQFAAFNPLFRSHGREWRLRLPWGWNRGEIGGFRETPAYNPDPAELHNAAIE
HHHHHHHHHHHHHCCHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
PVCKKYLELRYQMMPYLYSAVRETCETGMPIIRAMWLHYPGDAKAVGMGDQYLYGRDILV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHEECCCCCCEECCCCCEEECCCEEE
APVFEKGATSRAVYLPRGTWYDFWTREKLDGGREISRKVDLETIPLYVRAGAIVPMGPVK
EECCCCCCCCCEEEECCCCEECCCCHHHCCCCHHHHHCCCCEEEEEEEECCCCCCCCCCC
QYTWEKVDGPMTVWVYPGADGTFSWYEDDGASFNFRNGELMRVNLAWSHSQRRLTMRLAN
CCCHHHCCCCEEEEEECCCCCCEEEECCCCCEEEECCCCEEEEEEEECCCCEEEEEEEEC
GSKMLTPQRRGIVVRVAGESVSRNATFDGRPVEIQL
CCEECCCCCCCEEEEECCCCCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10801892; 11427726 [H]