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The map label for this gene is tolB [H]

Identifier: 116626608

GI number: 116626608

Start: 9488080

End: 9489996

Strand: Direct

Name: tolB [H]

Synonym: Acid_7571

Alternate gene names: 116626608

Gene position: 9488080-9489996 (Clockwise)

Preceding gene: 116626602

Following gene: 116626611

Centisome position: 95.21

GC content: 60.72

Gene sequence:

>1917_bases
TTGGGCGAAACGTTGCCGTACGCCTTGAGAGCCATTTATGATTACTTGCGTCGAGATGACCGGGGGACTACAATCCCTCA
AATGCGCTCACTGATAATCGCCCTCACCGCGATGGCCATCCTGTTGGCCGAAACCCACACACGCCGGAAGATCGCGCTAG
CCCGCGTGTACCCGCAGCCCGGCCAGCTTGGTCTTTTCGTTGCCGCGTCCGATGGAAGTGACGAGCATCCCCTGCTCGCA
TCCGCCGACACTGATTACGACCCGGCCTGGGCTCCGGACGGCGGATCTATCGTCTTCACCTCCGAACGAAACGGATCGGC
TGATCTTTTCCGAGTCAATCCGGACGGCAGCGGATTAAAGCAGCTCACCGCGGACCCGGCTTACGACGATCAGGCGACAT
TCTCTAGCGACAGCAAACAGCTGGCGTTCGTCAGCACGCGCGGCGGTGGTACGGCGAACCTTTGGACGATGGACCTGGTT
ACGGGGCGCGCCAGGGCACTTACCTCCGGCCCGGGCGGCGATTTTCGTCCGTCGTGGTCGCCGGATGGAAAGTGGATCGC
GTTCTCCTCAGGCCGCGACAACCCAGTGCCGTTCGCCAGCGGCCGGTGGGAGCGGCTTCAATTGTCGGACATTTACGTCA
TCCGTCCCGACGGCTCCGGGTTGAAGAAGATCACGAAGAGCGGGAATTTTTGCGGCAGCCCGAAATGGATGGGCGACAGC
AGTCACGTCATCGCCTATTGCATGACTGCCGAACAGACACTCGCAAATCGAAGGGCGAGTCCCGATCCCGGGAACGACAC
GCGGTTGGTCTCGATCGACACAGGCACCGCGGCCTCCACCGAATTGAACACCGGCCCGGGCGTCAAAATCAATCCGTCCT
GGCTGCCGGGCAACGAAACCGGCTACATACGAAAGGACACGGCGGATCCGGGCATCTACTACTCGAGCGGCAGACGGGGA
CCAGCCGGCCAGATTCGCGGCGCATCCTGGTCGCCCGATGGCAAACTGGTCGTGTTTTGTAGGCGTGCTAACACTCCGCG
GCCAGCCGGAGGCGCCAAGAGGACGTTCAGCCGCAATTCCAAATACGAACTGAGCCTGACGGGAATCCTGCCGGCATTTA
GCCCGTCGGGTAGGGAACTGGTTACCAACAGCCCGCCTTCCGCCACTCCACGGGGTTCCAGCATCAGCGTAACCGCGCTG
GAGACGGGGATTTCCAAGGTGGTCTACGAGGACAAGAACCGGAATGTGCTGGTGGGCGGGTGGTCGCCTGACGGTAGGCG
GATCATCTTCGCCATCGGTGAATTCGCCGCGTTCTTCGATGGCTTCCATTCCCGTTTTCTGAAAGTCGGCGATCGTGCGG
AGACCGGCGCTCGGCTGGCGATCGTTAACGCGGACGGGACCGGGTTAACGGAACTCACGGCGGAGCCGGGCAATAACGCA
TTCCCGTCGTTTTCTCCCGATGGCAAGCGGTTTGTGTACCGCACCTTCACCGAAGACGGGTACGGCCTGCGCATCATGAA
CCTCGAGACGAAGACAGGCAAGATCCTGACCCGGCAGTACGATAATTTCCCACTGTGGTCACCGCGCGGGGATCTAATCA
CGTTCTCGCGCCAAATCGAGGGCGCCTATGAGATCTACACGATTAAACCAGATGGAAGCTCCTTGAAGCGCCTCACCTTC
ACTAAAGGGAACGATGCGCACATGGCGTGGTCGCCTGACGGCGAGTACATCGTATTCACCAGTTCGAGGATGGGCTTCAA
GGATGAAGTCGCCTATACCGATGCGCCGCAGCCCTATGGCGAGATTTTCGTGATGCGCTACGACGGCACCGGCGTTGAGC
AGCTCACCGATAACCAATGGGAGGAGGGCACTCCCGCCTGGCAGCCAATGGCCGCCAGCCACATAGGGGGCCGTTAA

Upstream 100 bases:

>100_bases
TGTCGCGAGTGTAAGAATCCCATGTGAGTCGGCTGGTGGTACGATCTGCTTCCAGGCTAAAGGACCCCCCTTAGCAAGGA
CATACCAGGAACAGGGTATT

Downstream 100 bases:

>100_bases
AGAGCACCACCCAAAGCGCGTCACCCGTCAGCGCAGGGCGATCCAGCCAGTTAGTGCACGGGCACGCGACGCCGCAACTC
ATCGAAAAAGTTCAGTAAAA

Product: WD40 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 638; Mature: 637

Protein sequence:

>638_residues
MGETLPYALRAIYDYLRRDDRGTTIPQMRSLIIALTAMAILLAETHTRRKIALARVYPQPGQLGLFVAASDGSDEHPLLA
SADTDYDPAWAPDGGSIVFTSERNGSADLFRVNPDGSGLKQLTADPAYDDQATFSSDSKQLAFVSTRGGGTANLWTMDLV
TGRARALTSGPGGDFRPSWSPDGKWIAFSSGRDNPVPFASGRWERLQLSDIYVIRPDGSGLKKITKSGNFCGSPKWMGDS
SHVIAYCMTAEQTLANRRASPDPGNDTRLVSIDTGTAASTELNTGPGVKINPSWLPGNETGYIRKDTADPGIYYSSGRRG
PAGQIRGASWSPDGKLVVFCRRANTPRPAGGAKRTFSRNSKYELSLTGILPAFSPSGRELVTNSPPSATPRGSSISVTAL
ETGISKVVYEDKNRNVLVGGWSPDGRRIIFAIGEFAAFFDGFHSRFLKVGDRAETGARLAIVNADGTGLTELTAEPGNNA
FPSFSPDGKRFVYRTFTEDGYGLRIMNLETKTGKILTRQYDNFPLWSPRGDLITFSRQIEGAYEIYTIKPDGSSLKRLTF
TKGNDAHMAWSPDGEYIVFTSSRMGFKDEVAYTDAPQPYGEIFVMRYDGTGVEQLTDNQWEEGTPAWQPMAASHIGGR

Sequences:

>Translated_638_residues
MGETLPYALRAIYDYLRRDDRGTTIPQMRSLIIALTAMAILLAETHTRRKIALARVYPQPGQLGLFVAASDGSDEHPLLA
SADTDYDPAWAPDGGSIVFTSERNGSADLFRVNPDGSGLKQLTADPAYDDQATFSSDSKQLAFVSTRGGGTANLWTMDLV
TGRARALTSGPGGDFRPSWSPDGKWIAFSSGRDNPVPFASGRWERLQLSDIYVIRPDGSGLKKITKSGNFCGSPKWMGDS
SHVIAYCMTAEQTLANRRASPDPGNDTRLVSIDTGTAASTELNTGPGVKINPSWLPGNETGYIRKDTADPGIYYSSGRRG
PAGQIRGASWSPDGKLVVFCRRANTPRPAGGAKRTFSRNSKYELSLTGILPAFSPSGRELVTNSPPSATPRGSSISVTAL
ETGISKVVYEDKNRNVLVGGWSPDGRRIIFAIGEFAAFFDGFHSRFLKVGDRAETGARLAIVNADGTGLTELTAEPGNNA
FPSFSPDGKRFVYRTFTEDGYGLRIMNLETKTGKILTRQYDNFPLWSPRGDLITFSRQIEGAYEIYTIKPDGSSLKRLTF
TKGNDAHMAWSPDGEYIVFTSSRMGFKDEVAYTDAPQPYGEIFVMRYDGTGVEQLTDNQWEEGTPAWQPMAASHIGGR
>Mature_637_residues
GETLPYALRAIYDYLRRDDRGTTIPQMRSLIIALTAMAILLAETHTRRKIALARVYPQPGQLGLFVAASDGSDEHPLLAS
ADTDYDPAWAPDGGSIVFTSERNGSADLFRVNPDGSGLKQLTADPAYDDQATFSSDSKQLAFVSTRGGGTANLWTMDLVT
GRARALTSGPGGDFRPSWSPDGKWIAFSSGRDNPVPFASGRWERLQLSDIYVIRPDGSGLKKITKSGNFCGSPKWMGDSS
HVIAYCMTAEQTLANRRASPDPGNDTRLVSIDTGTAASTELNTGPGVKINPSWLPGNETGYIRKDTADPGIYYSSGRRGP
AGQIRGASWSPDGKLVVFCRRANTPRPAGGAKRTFSRNSKYELSLTGILPAFSPSGRELVTNSPPSATPRGSSISVTALE
TGISKVVYEDKNRNVLVGGWSPDGRRIIFAIGEFAAFFDGFHSRFLKVGDRAETGARLAIVNADGTGLTELTAEPGNNAF
PSFSPDGKRFVYRTFTEDGYGLRIMNLETKTGKILTRQYDNFPLWSPRGDLITFSRQIEGAYEIYTIKPDGSSLKRLTFT
KGNDAHMAWSPDGEYIVFTSSRMGFKDEVAYTDAPQPYGEIFVMRYDGTGVEQLTDNQWEEGTPAWQPMAASHIGGR

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0823

COG function: function code U; Periplasmic component of the Tol biopolymer transport system

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tolB family [H]

Homologues:

Organism=Escherichia coli, GI1786961, Length=165, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011659
- InterPro:   IPR014167
- InterPro:   IPR007195
- InterPro:   IPR015943 [H]

Pfam domain/function: PF07676 PD40; PF04052 TolB_N [H]

EC number: NA

Molecular weight: Translated: 69365; Mature: 69234

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGETLPYALRAIYDYLRRDDRGTTIPQMRSLIIALTAMAILLAETHTRRKIALARVYPQP
CCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCC
GQLGLFVAASDGSDEHPLLASADTDYDPAWAPDGGSIVFTSERNGSADLFRVNPDGSGLK
CCEEEEEEECCCCCCCCEEEECCCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCHH
QLTADPAYDDQATFSSDSKQLAFVSTRGGGTANLWTMDLVTGRARALTSGPGGDFRPSWS
HHCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEEEECCCCEEEECCCCCCCCCCCC
PDGKWIAFSSGRDNPVPFASGRWERLQLSDIYVIRPDGSGLKKITKSGNFCGSPKWMGDS
CCCCEEEECCCCCCCCCCCCCCCCEEEECEEEEECCCCCCHHHHHHCCCCCCCCCCCCCC
SHVIAYCMTAEQTLANRRASPDPGNDTRLVSIDTGTAASTELNTGPGVKINPSWLPGNET
CCEEEEEEEHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEECCCCCCCCCC
GYIRKDTADPGIYYSSGRRGPAGQIRGASWSPDGKLVVFCRRANTPRPAGGAKRTFSRNS
CEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCC
KYELSLTGILPAFSPSGRELVTNSPPSATPRGSSISVTALETGISKVVYEDKNRNVLVGG
EEEEEEEEECCCCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCEEEEEECCCCEEEEEC
WSPDGRRIIFAIGEFAAFFDGFHSRFLKVGDRAETGARLAIVNADGTGLTELTAEPGNNA
CCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEECCCCCC
FPSFSPDGKRFVYRTFTEDGYGLRIMNLETKTGKILTRQYDNFPLWSPRGDLITFSRQIE
CCCCCCCCCEEEEEEECCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCEEEEEEECC
GAYEIYTIKPDGSSLKRLTFTKGNDAHMAWSPDGEYIVFTSSRMGFKDEVAYTDAPQPYG
CEEEEEEECCCCCCCEEEEEECCCCCEEEECCCCCEEEEECCCCCCCCCEEECCCCCCCC
EIFVMRYDGTGVEQLTDNQWEEGTPAWQPMAASHIGGR
CEEEEEECCCCHHHHCCCCCCCCCCCCCCCHHHHCCCC
>Mature Secondary Structure 
GETLPYALRAIYDYLRRDDRGTTIPQMRSLIIALTAMAILLAETHTRRKIALARVYPQP
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCC
GQLGLFVAASDGSDEHPLLASADTDYDPAWAPDGGSIVFTSERNGSADLFRVNPDGSGLK
CCEEEEEEECCCCCCCCEEEECCCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCHH
QLTADPAYDDQATFSSDSKQLAFVSTRGGGTANLWTMDLVTGRARALTSGPGGDFRPSWS
HHCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEEEECCCCEEEECCCCCCCCCCCC
PDGKWIAFSSGRDNPVPFASGRWERLQLSDIYVIRPDGSGLKKITKSGNFCGSPKWMGDS
CCCCEEEECCCCCCCCCCCCCCCCEEEECEEEEECCCCCCHHHHHHCCCCCCCCCCCCCC
SHVIAYCMTAEQTLANRRASPDPGNDTRLVSIDTGTAASTELNTGPGVKINPSWLPGNET
CCEEEEEEEHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEECCCCCCCCCC
GYIRKDTADPGIYYSSGRRGPAGQIRGASWSPDGKLVVFCRRANTPRPAGGAKRTFSRNS
CEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCC
KYELSLTGILPAFSPSGRELVTNSPPSATPRGSSISVTALETGISKVVYEDKNRNVLVGG
EEEEEEEEECCCCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCEEEEEECCCCEEEEEC
WSPDGRRIIFAIGEFAAFFDGFHSRFLKVGDRAETGARLAIVNADGTGLTELTAEPGNNA
CCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEECCCCCC
FPSFSPDGKRFVYRTFTEDGYGLRIMNLETKTGKILTRQYDNFPLWSPRGDLITFSRQIE
CCCCCCCCCEEEEEEECCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCEEEEEEECC
GAYEIYTIKPDGSSLKRLTFTKGNDAHMAWSPDGEYIVFTSSRMGFKDEVAYTDAPQPYG
CEEEEEEECCCCCCCEEEEEECCCCCEEEECCCCCEEEEECCCCCCCCCEEECCCCCCCC
EIFVMRYDGTGVEQLTDNQWEEGTPAWQPMAASHIGGR
CEEEEEECCCCHHHHCCCCCCCCCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA