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The map label for this gene is cusB [H]

Identifier: 116626550

GI number: 116626550

Start: 9412040

End: 9413284

Strand: Direct

Name: cusB [H]

Synonym: Acid_7513

Alternate gene names: 116626550

Gene position: 9412040-9413284 (Clockwise)

Preceding gene: 116626549

Following gene: 116626551

Centisome position: 94.44

GC content: 63.86

Gene sequence:

>1245_bases
ATGAAGACCTTGCTCGCCTTGGCGGCGATTGGCCTCGCCTGGGCCGGCGGTTACGGTTATGGACGCTGGTACGCCAAGCC
CGCCCCGGGGGAAAAGAAGCCGCTCTACTGGGTGGACCCGATGCATCCCTGGTACAAGAGCGACAAGCCCGGCGTCGCGC
CCGACTGCAATATGAAACTGGTGCCCGTGATGGCCGGAGACGAAGCGCGCTACGAACGCCGCGCCAACCGGATGCCCGAG
GGCAGCGTGCAGATCACCCCGGAGAAGCAGCAGCTGATCGGCGTTGAGTACGGCGCCGTGGAGTACGAGAATGTCTCCGG
CGCGCTGCGCGCGGCCGCGCGCGTCACGCTCGACGAGACCAAAATCTCGAAGGTGAACAGCAAGCTCGAAGGCTGGCTGG
AGCAGGTCTTCGTGGATTCCATCGGCCGGCAGGTGAACAAGGGCGAGCCGCTGGTGACGATCTACAGCCCCGAGGCCCTC
GCCACACAGCAGGAATACCTGTTGGCCATCAAGGGCCGCGACATGATGCACGATAGTCCGGTGCACGAGATGCTCGGCAG
CACGGAAAACCTGATCGCCGCCGCCAGAAAGCGCCTCGAGCTTTGGGATATCGGCGAGTCGCAGATCGCCGCCATCACCA
CTGCCGGCCAGGCGGTTAAGTACCTGACGCTGTACGCGCCGGCCTCGGGCGTCGTGATGGAGCGCAACGCCTTCGCCAAA
CAACGCATTATGCCGGACACCGTGCTCTACAACATCGCCGATCTCTCCACTGTTTGGGTTGTGGCCGACGTCTTTGAATA
CGAGGCCGCGGGTGTGCGGATCGGCCAGGCGGCGGCGCTCACGCTCGCGTATCTGCCGGGCCGCACTTTCCGCGGACACG
TGAGCTACATTCTCCCCACCATCGACCCTGCGACCCGTACGGTCAAAGTCCGCGTCGAATTTTCGAACCCCGAGTTCCTG
CTGAAGCCGGAGATGTACGGCGAAGTGGAGTTTCAGACCGGCGGCACGCGGCGGCTGGTGGTGCCTCAGACCGCCGTACT
CAACTCGGGCGACCGTCAGACGGTCTTCGTGGATCGCGGCAACGGATATTTCGAGCCGCGCGACGTGAAGATCGGCGCGC
AGAACTCGGGCCGCACCGAAATCCTGAGCGGTCTCAAGGCCGGCGAGCGTATCGTGATCTCCGGCAACTTCCTGATCGAT
TCCGAAAGTCAGCTCAAGACTGCGCTCGGCGGAGCCTCGAAATGA

Upstream 100 bases:

>100_bases
ATTTCATGAATGTTGTGGAGTACGAACTCATGGTGCACGAAGAAATCATGCAATTCCACGTGGCGCTGGCGCGCCTGGAA
GAACTCACCGGGGTGGCGTT

Downstream 100 bases:

>100_bases
TCGACCGGATTATCGAGTTCTCCGCGCACAATCGCTTCCTGGTCTTCCTGTTCGTGGCCGGGTTGGCGCTGGCGGGCTTC
TGGTCGATGAACCACATTCC

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MKTLLALAAIGLAWAGGYGYGRWYAKPAPGEKKPLYWVDPMHPWYKSDKPGVAPDCNMKLVPVMAGDEARYERRANRMPE
GSVQITPEKQQLIGVEYGAVEYENVSGALRAAARVTLDETKISKVNSKLEGWLEQVFVDSIGRQVNKGEPLVTIYSPEAL
ATQQEYLLAIKGRDMMHDSPVHEMLGSTENLIAAARKRLELWDIGESQIAAITTAGQAVKYLTLYAPASGVVMERNAFAK
QRIMPDTVLYNIADLSTVWVVADVFEYEAAGVRIGQAAALTLAYLPGRTFRGHVSYILPTIDPATRTVKVRVEFSNPEFL
LKPEMYGEVEFQTGGTRRLVVPQTAVLNSGDRQTVFVDRGNGYFEPRDVKIGAQNSGRTEILSGLKAGERIVISGNFLID
SESQLKTALGGASK

Sequences:

>Translated_414_residues
MKTLLALAAIGLAWAGGYGYGRWYAKPAPGEKKPLYWVDPMHPWYKSDKPGVAPDCNMKLVPVMAGDEARYERRANRMPE
GSVQITPEKQQLIGVEYGAVEYENVSGALRAAARVTLDETKISKVNSKLEGWLEQVFVDSIGRQVNKGEPLVTIYSPEAL
ATQQEYLLAIKGRDMMHDSPVHEMLGSTENLIAAARKRLELWDIGESQIAAITTAGQAVKYLTLYAPASGVVMERNAFAK
QRIMPDTVLYNIADLSTVWVVADVFEYEAAGVRIGQAAALTLAYLPGRTFRGHVSYILPTIDPATRTVKVRVEFSNPEFL
LKPEMYGEVEFQTGGTRRLVVPQTAVLNSGDRQTVFVDRGNGYFEPRDVKIGAQNSGRTEILSGLKAGERIVISGNFLID
SESQLKTALGGASK
>Mature_414_residues
MKTLLALAAIGLAWAGGYGYGRWYAKPAPGEKKPLYWVDPMHPWYKSDKPGVAPDCNMKLVPVMAGDEARYERRANRMPE
GSVQITPEKQQLIGVEYGAVEYENVSGALRAAARVTLDETKISKVNSKLEGWLEQVFVDSIGRQVNKGEPLVTIYSPEAL
ATQQEYLLAIKGRDMMHDSPVHEMLGSTENLIAAARKRLELWDIGESQIAAITTAGQAVKYLTLYAPASGVVMERNAFAK
QRIMPDTVLYNIADLSTVWVVADVFEYEAAGVRIGQAAALTLAYLPGRTFRGHVSYILPTIDPATRTVKVRVEFSNPEFL
LKPEMYGEVEFQTGGTRRLVVPQTAVLNSGDRQTVFVDRGNGYFEPRDVKIGAQNSGRTEILSGLKAGERIVISGNFLID
SESQLKTALGGASK

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=411, Percent_Identity=30.6569343065693, Blast_Score=177, Evalue=8e-46,
Organism=Escherichia coli, GI87081796, Length=191, Percent_Identity=29.8429319371728, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 45462; Mature: 45462

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLLALAAIGLAWAGGYGYGRWYAKPAPGEKKPLYWVDPMHPWYKSDKPGVAPDCNMKL
CHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEE
VPVMAGDEARYERRANRMPEGSVQITPEKQQLIGVEYGAVEYENVSGALRAAARVTLDET
EEEEECCHHHHHHHHCCCCCCCEEECCCHHHEEEEEECCEEECCCCHHHHHHEEEEECHH
KISKVNSKLEGWLEQVFVDSIGRQVNKGEPLVTIYSPEALATQQEYLLAIKGRDMMHDSP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHCCCCEEEEEECCCCCCCCCH
VHEMLGSTENLIAAARKRLELWDIGESQIAAITTAGQAVKYLTLYAPASGVVMERNAFAK
HHHHHCCHHHHHHHHHHCCEEEECCCCCEEEEEECCCEEEEEEEECCCCCEEEECCHHHH
QRIMPDTVLYNIADLSTVWVVADVFEYEAAGVRIGQAAALTLAYLPGRTFRGHVSYILPT
HHCCCHHHEEEHHHHHHHHHHHHHHHHHCCCEEECCHHEEEEEECCCCCEECEEEEEEEC
IDPATRTVKVRVEFSNPEFLLKPEMYGEVEFQTGGTRRLVVPQTAVLNSGDRQTVFVDRG
CCCCCEEEEEEEEECCCCEEECCCCCCEEEEECCCEEEEEECCHHHCCCCCCEEEEEECC
NGYFEPRDVKIGAQNSGRTEILSGLKAGERIVISGNFLIDSESQLKTALGGASK
CCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEEECCEEECCHHHHHHHHCCCCC
>Mature Secondary Structure
MKTLLALAAIGLAWAGGYGYGRWYAKPAPGEKKPLYWVDPMHPWYKSDKPGVAPDCNMKL
CHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEE
VPVMAGDEARYERRANRMPEGSVQITPEKQQLIGVEYGAVEYENVSGALRAAARVTLDET
EEEEECCHHHHHHHHCCCCCCCEEECCCHHHEEEEEECCEEECCCCHHHHHHEEEEECHH
KISKVNSKLEGWLEQVFVDSIGRQVNKGEPLVTIYSPEALATQQEYLLAIKGRDMMHDSP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHCCCCEEEEEECCCCCCCCCH
VHEMLGSTENLIAAARKRLELWDIGESQIAAITTAGQAVKYLTLYAPASGVVMERNAFAK
HHHHHCCHHHHHHHHHHCCEEEECCCCCEEEEEECCCEEEEEEEECCCCCEEEECCHHHH
QRIMPDTVLYNIADLSTVWVVADVFEYEAAGVRIGQAAALTLAYLPGRTFRGHVSYILPT
HHCCCHHHEEEHHHHHHHHHHHHHHHHHCCCEEECCHHEEEEEECCCCCEECEEEEEEEC
IDPATRTVKVRVEFSNPEFLLKPEMYGEVEFQTGGTRRLVVPQTAVLNSGDRQTVFVDRG
CCCCCEEEEEEEEECCCCEEECCCCCCEEEEECCCEEEEEECCHHHCCCCCCEEEEEECC
NGYFEPRDVKIGAQNSGRTEILSGLKAGERIVISGNFLIDSESQLKTALGGASK
CCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEEECCEEECCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]