Click here to switch to the map view.

The map label for this gene is frdB [H]

Identifier: 116626441

GI number: 116626441

Start: 9289091

End: 9289852

Strand: Direct

Name: frdB [H]

Synonym: Acid_7403

Alternate gene names: 116626441

Gene position: 9289091-9289852 (Clockwise)

Preceding gene: 116626440

Following gene: 116626443

Centisome position: 93.21

GC content: 62.34

Gene sequence:

>762_bases
ATGCGAATCATTCTCCATATCTGGCGGCAGCGCAACGCGAGCGATAAGGGCAAGATGGTGCGGTACGAGGTACCGGACGT
CAACCACGAAATGTCCTTTCTAGAGATGCTCGACGTTCTGAATGAGGATTTGATCGCCAGGAACGAAGACCCCGTGGCGT
TTGACCACGATTGCCGCGAAGGCATCTGCGGGACGTGCGGGGCCATGGTGAACGGCGTGGCGCACGGACCGCTGCCGGGC
ACGACGCTGTGCCAGCTGCACATGCGCCATTTCAAGGATGGCGATGAGCTCTACCTGGAACCGTGGCGGGCCAAAGCCTT
TCCGGTGGTGAAGGACCTGGTGGTTAACCGCGGCGCTTTCGACCGGATTATCGCGGCGGGCGGCTACATTTCCGTATCGA
CGGGCAGCGCGCAGGATGGCAATGCGATTCTGGTGCCGAAGGAGAATGCGGAGCGGAGCATGGACGCGGCGGCATGCATC
GGGTGCGGCGCGTGCGTCGCGATGTGTCCGAATGCGTCGGCGGCGTTGTTTACCGGCGCCAAGATCGCACACCTGGGATT
GCTGCCGCAGGGGCAGCCGGAGCGCGAGCAGCGGGCGATCGCGATGGTGGCGCAGGCGAAGCAGGAGCTATTCGGCAGCT
GCACCAATATCGGAGAATGCGAAGCGGTGTGCCCGAAGGAGATCAAGCTGGAAGTGATCGCCCGGATGAACCGGGATTTC
ATTAAGGCCAGCATCACGGGTCGCGGCGTACCGGTGGAGTAA

Upstream 100 bases:

>100_bases
CGGCGGCCTGGGAATACAAGGGCCCGGGCGCGGAGCCGGCGCTGAACAAGGAGCCGCTGACTTTCGAATACGTGCACCCC
TCGCAACGGAGCTACAAGTA

Downstream 100 bases:

>100_bases
GGCTGGGGCGAAGCAGGAGCGCGTTAGATCGCTCCCTTACTTTACGGTCGCGGCTCTTTGACCAGGGTCTGGGGGTCGAG
GAAGTGCTTGGGCTGGAAGG

Product: succinate dehydrogenase/fumarate reductase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MRIILHIWRQRNASDKGKMVRYEVPDVNHEMSFLEMLDVLNEDLIARNEDPVAFDHDCREGICGTCGAMVNGVAHGPLPG
TTLCQLHMRHFKDGDELYLEPWRAKAFPVVKDLVVNRGAFDRIIAAGGYISVSTGSAQDGNAILVPKENAERSMDAAACI
GCGACVAMCPNASAALFTGAKIAHLGLLPQGQPEREQRAIAMVAQAKQELFGSCTNIGECEAVCPKEIKLEVIARMNRDF
IKASITGRGVPVE

Sequences:

>Translated_253_residues
MRIILHIWRQRNASDKGKMVRYEVPDVNHEMSFLEMLDVLNEDLIARNEDPVAFDHDCREGICGTCGAMVNGVAHGPLPG
TTLCQLHMRHFKDGDELYLEPWRAKAFPVVKDLVVNRGAFDRIIAAGGYISVSTGSAQDGNAILVPKENAERSMDAAACI
GCGACVAMCPNASAALFTGAKIAHLGLLPQGQPEREQRAIAMVAQAKQELFGSCTNIGECEAVCPKEIKLEVIARMNRDF
IKASITGRGVPVE
>Mature_253_residues
MRIILHIWRQRNASDKGKMVRYEVPDVNHEMSFLEMLDVLNEDLIARNEDPVAFDHDCREGICGTCGAMVNGVAHGPLPG
TTLCQLHMRHFKDGDELYLEPWRAKAFPVVKDLVVNRGAFDRIIAAGGYISVSTGSAQDGNAILVPKENAERSMDAAACI
GCGACVAMCPNASAALFTGAKIAHLGLLPQGQPEREQRAIAMVAQAKQELFGSCTNIGECEAVCPKEIKLEVIARMNRDF
IKASITGRGVPVE

Specific function: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth [H]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790596, Length=234, Percent_Identity=27.3504273504274, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 27477; Mature: 27477

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS00197 2FE2S_FER_1 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
8.3 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
8.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIILHIWRQRNASDKGKMVRYEVPDVNHEMSFLEMLDVLNEDLIARNEDPVAFDHDCRE
CEEEEEEHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCHHHC
GICGTCGAMVNGVAHGPLPGTTLCQLHMRHFKDGDELYLEPWRAKAFPVVKDLVVNRGAF
CHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHCCCCH
DRIIAAGGYISVSTGSAQDGNAILVPKENAERSMDAAACIGCGACVAMCPNASAALFTGA
HHHHHCCCEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHCCC
KIAHLGLLPQGQPEREQRAIAMVAQAKQELFGSCTNIGECEAVCPKEIKLEVIARMNRDF
HHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCHHH
IKASITGRGVPVE
EEEEECCCCCCCC
>Mature Secondary Structure
MRIILHIWRQRNASDKGKMVRYEVPDVNHEMSFLEMLDVLNEDLIARNEDPVAFDHDCRE
CEEEEEEHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCEECCHHHC
GICGTCGAMVNGVAHGPLPGTTLCQLHMRHFKDGDELYLEPWRAKAFPVVKDLVVNRGAF
CHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHCCCCH
DRIIAAGGYISVSTGSAQDGNAILVPKENAERSMDAAACIGCGACVAMCPNASAALFTGA
HHHHHCCCEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHCCC
KIAHLGLLPQGQPEREQRAIAMVAQAKQELFGSCTNIGECEAVCPKEIKLEVIARMNRDF
HHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCHHH
IKASITGRGVPVE
EEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]