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The map label for this gene is dnaX [H]

Identifier: 116626371

GI number: 116626371

Start: 9204581

End: 9205609

Strand: Direct

Name: dnaX [H]

Synonym: Acid_7331

Alternate gene names: 116626371

Gene position: 9204581-9205609 (Clockwise)

Preceding gene: 116626370

Following gene: 116626375

Centisome position: 92.36

GC content: 64.04

Gene sequence:

>1029_bases
ATGTTTGAAAACTTCTGGGGTAATACCGCCGTCACCGAAGCGCTGGAACAGATGATCGCGCAGCAGCGCGTTTCGCAGAC
CCTGCTCTTCTCCGGCCCCGAAGGCGTCGGCAAGGCCACCCTCGCCCGCCGCCTCGGCGCCCGCCTTCTCGCCCATCCGG
AGTTGATCGAGCGGGACGACCTGGCCTTGCCCGAAAATCTGGAGACCATCGCCACCCGCGAAAAGTGGACCGCGGAGAAG
CGCAATGAGGATCCCCTTCAATTCGCGACTCACCCGGATTTCGTCACCTTCCCGCCCGATGGCCCTCTGCGCCAGATCTC
CATCCCGCAGACGCGCCGCCTCAAGGACGCCGCCCAGTACCTGCCCCATAAGGGCAGCCGCCGAATTTTCCTGATCGATC
ACGTGGACCGCGCCAACGATCAGGCCGCCAACTCCCTGCTCAAAACCCTGGAAGAGCCGCCCGACCACCTGATCCTGATC
ATGACCGCGCAAAACGCCTACGATCTGCTGCCCACCATCCGCTCGCGCGCCGTCCCTTTCTACTTCGCCCCGCTCGCCCC
CGCCGAGATGCGCGCCTTTGTGAAGGCCCGCGGCCTGGACCAGCCCGAGCGACGCATCGCGCTCGCCGCCGGCAGCCCCG
GCATCGCCATGTCACTCGATCTCGAGGCCTACGACAAACGCCGCGCCGCCATGCTGGTGCTGCTCAAAGCCGCCGCCGGC
GCCGCCCCCTTCTCCGCCTGGATCCCGATCGGTGAAACCATCGGCCGCAGCAAAAGCGAAAAGCTCGAGCTTTACCTCAA
GGTGCTCTACGAACTGTTGCGCGATCTTCTGATGCTCCATGAAGGCGGCGGCGAAATCCGCAATCAGGATATCCGCCGCG
ACCTCGAAGTCCTCTCCGCCAAGATCGAATTCACCTGGATCCGCAAAGCCGTCACACGTGTCGATGAGGTCGCCATGCTC
CTCCGCCGCAACATCCAGAAGACCATCGCCCTAGACGCCCTCATCCTCGAACTCCGCGGCATCTCATAA

Upstream 100 bases:

>100_bases
CACGCGCTCGCCGCCGCTGAACCAGAGCGCGTGAAGGTGGCCAACGGCCGCGCCGGAATGGACGAGATCGAACGCGAAAT
CTGGAGTATCGTAAGCGCGC

Downstream 100 bases:

>100_bases
CTTCTTCCGCGGTCGGAGCCGCGACCGTAAGGAAGCGGTCGGTAATCTGCCTTTGCGTGCTCAGCGGAGCAATTTAATTC
CGACCTATCTACTTCACCCA

Product: DNA polymerase III subunit delta'

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MFENFWGNTAVTEALEQMIAQQRVSQTLLFSGPEGVGKATLARRLGARLLAHPELIERDDLALPENLETIATREKWTAEK
RNEDPLQFATHPDFVTFPPDGPLRQISIPQTRRLKDAAQYLPHKGSRRIFLIDHVDRANDQAANSLLKTLEEPPDHLILI
MTAQNAYDLLPTIRSRAVPFYFAPLAPAEMRAFVKARGLDQPERRIALAAGSPGIAMSLDLEAYDKRRAAMLVLLKAAAG
AAPFSAWIPIGETIGRSKSEKLELYLKVLYELLRDLLMLHEGGGEIRNQDIRRDLEVLSAKIEFTWIRKAVTRVDEVAML
LRRNIQKTIALDALILELRGIS

Sequences:

>Translated_342_residues
MFENFWGNTAVTEALEQMIAQQRVSQTLLFSGPEGVGKATLARRLGARLLAHPELIERDDLALPENLETIATREKWTAEK
RNEDPLQFATHPDFVTFPPDGPLRQISIPQTRRLKDAAQYLPHKGSRRIFLIDHVDRANDQAANSLLKTLEEPPDHLILI
MTAQNAYDLLPTIRSRAVPFYFAPLAPAEMRAFVKARGLDQPERRIALAAGSPGIAMSLDLEAYDKRRAAMLVLLKAAAG
AAPFSAWIPIGETIGRSKSEKLELYLKVLYELLRDLLMLHEGGGEIRNQDIRRDLEVLSAKIEFTWIRKAVTRVDEVAML
LRRNIQKTIALDALILELRGIS
>Mature_342_residues
MFENFWGNTAVTEALEQMIAQQRVSQTLLFSGPEGVGKATLARRLGARLLAHPELIERDDLALPENLETIATREKWTAEK
RNEDPLQFATHPDFVTFPPDGPLRQISIPQTRRLKDAAQYLPHKGSRRIFLIDHVDRANDQAANSLLKTLEEPPDHLILI
MTAQNAYDLLPTIRSRAVPFYFAPLAPAEMRAFVKARGLDQPERRIALAAGSPGIAMSLDLEAYDKRRAAMLVLLKAAAG
AAPFSAWIPIGETIGRSKSEKLELYLKVLYELLRDLLMLHEGGGEIRNQDIRRDLEVLSAKIEFTWIRKAVTRVDEVAML
LRRNIQKTIALDALILELRGIS

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786676, Length=190, Percent_Identity=29.4736842105263, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 38453; Mature: 38453

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: PS00334 MYB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFENFWGNTAVTEALEQMIAQQRVSQTLLFSGPEGVGKATLARRLGARLLAHPELIERDD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCCHHHCCCC
LALPENLETIATREKWTAEKRNEDPLQFATHPDFVTFPPDGPLRQISIPQTRRLKDAAQY
CCCCCCHHHHHHHHHHHHHCCCCCCCEECCCCCEEEECCCCCCEEECCCHHHHHHHHHHH
LPHKGSRRIFLIDHVDRANDQAANSLLKTLEEPPDHLILIMTAQNAYDLLPTIRSRAVPF
CCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCE
YFAPLAPAEMRAFVKARGLDQPERRIALAAGSPGIAMSLDLEAYDKRRAAMLVLLKAAAG
EECCCCHHHHHHHHHHCCCCCHHHEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHCC
AAPFSAWIPIGETIGRSKSEKLELYLKVLYELLRDLLMLHEGGGEIRNQDIRRDLEVLSA
CCCCHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
KIEFTWIRKAVTRVDEVAMLLRRNIQKTIALDALILELRGIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFENFWGNTAVTEALEQMIAQQRVSQTLLFSGPEGVGKATLARRLGARLLAHPELIERDD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCCHHHCCCC
LALPENLETIATREKWTAEKRNEDPLQFATHPDFVTFPPDGPLRQISIPQTRRLKDAAQY
CCCCCCHHHHHHHHHHHHHCCCCCCCEECCCCCEEEECCCCCCEEECCCHHHHHHHHHHH
LPHKGSRRIFLIDHVDRANDQAANSLLKTLEEPPDHLILIMTAQNAYDLLPTIRSRAVPF
CCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCE
YFAPLAPAEMRAFVKARGLDQPERRIALAAGSPGIAMSLDLEAYDKRRAAMLVLLKAAAG
EECCCCHHHHHHHHHHCCCCCHHHEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHCC
AAPFSAWIPIGETIGRSKSEKLELYLKVLYELLRDLLMLHEGGGEIRNQDIRRDLEVLSA
CCCCHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
KIEFTWIRKAVTRVDEVAMLLRRNIQKTIALDALILELRGIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]