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The map label for this gene is kdsC [H]

Identifier: 116626125

GI number: 116626125

Start: 8898996

End: 8899583

Strand: Direct

Name: kdsC [H]

Synonym: Acid_7083

Alternate gene names: 116626125

Gene position: 8898996-8899583 (Clockwise)

Preceding gene: 116626124

Following gene: 116626126

Centisome position: 89.3

GC content: 60.88

Gene sequence:

>588_bases
ATGAGCGCGGACGTCCCTCGTCTCGCCTCCAAAATCCGCTTGCTGCTGATGGACGTCGATGGCGTCCTCACCGATGGCAA
GCTCTATAACGTGCCGGGACCCGACGGCAAGATGGCGGAGACCAAGGGCTTCGATTCCCAGGACGGCATCGCGCTCCAAT
GGATGGCGCGCCTGGGAATCGCCACCGGCCTGATCAGCGGGCGCGTCTCCCCGGCCACCGTGGAGCGCGCCCATCAATGC
AAATTCAAGTACATCTACCAGGGCCATACGGAGAAGATCCCGATTCTCAATGAGATCCTCGCCGATGCCAAACTCGACCC
CTCCGAAGTGGCCTACATTGGCGACGATTTCACCGACGTCGTCGTCATGCGCCGCGTCGGCCTCAGCTTTGCCACCGCCA
ACGCCCGCTCTGAAATGAAATCCATCGCTCACTACGTCACCGCCACACCGGGCGGTCAGGGCGCGGTCCGCGAGGTCGTC
GAAGTTATCTTGAAAGCGCAGGGCAAGTGGGATGAAATCCTGCGTCACTACGAAGTCATTACCGATCCGCGACCGGCAGG
GCGCGATGTAAGTCTAGGAGAAGCTTAA

Upstream 100 bases:

>100_bases
GCGCCCACACCTTCGAGCGCGTCGATCAGCCGCGCGGCAAGTTCTTCCACACCAATTGGACCGGCAAGGGCGGCAACGTC
TCGGCCGGAGTCTACACCGT

Downstream 100 bases:

>100_bases
TGTCTACCGGCCTCAATATTCGTAAAGAGGGCGCCCTCGATTTCCTCTCTCTCGGCGCCCTGGTTCACCGCCTCGATCCC
GGGATCATTCCCTTTCGTAA

Product: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MSADVPRLASKIRLLLMDVDGVLTDGKLYNVPGPDGKMAETKGFDSQDGIALQWMARLGIATGLISGRVSPATVERAHQC
KFKYIYQGHTEKIPILNEILADAKLDPSEVAYIGDDFTDVVVMRRVGLSFATANARSEMKSIAHYVTATPGGQGAVREVV
EVILKAQGKWDEILRHYEVITDPRPAGRDVSLGEA

Sequences:

>Translated_195_residues
MSADVPRLASKIRLLLMDVDGVLTDGKLYNVPGPDGKMAETKGFDSQDGIALQWMARLGIATGLISGRVSPATVERAHQC
KFKYIYQGHTEKIPILNEILADAKLDPSEVAYIGDDFTDVVVMRRVGLSFATANARSEMKSIAHYVTATPGGQGAVREVV
EVILKAQGKWDEILRHYEVITDPRPAGRDVSLGEA
>Mature_194_residues
SADVPRLASKIRLLLMDVDGVLTDGKLYNVPGPDGKMAETKGFDSQDGIALQWMARLGIATGLISGRVSPATVERAHQCK
FKYIYQGHTEKIPILNEILADAKLDPSEVAYIGDDFTDVVVMRRVGLSFATANARSEMKSIAHYVTATPGGQGAVREVVE
VILKAQGKWDEILRHYEVITDPRPAGRDVSLGEA

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=156, Percent_Identity=32.6923076923077, Blast_Score=79, Evalue=3e-15,
Organism=Escherichia coli, GI2367202, Length=172, Percent_Identity=41.2790697674419, Blast_Score=124, Evalue=6e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 21210; Mature: 21078

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSADVPRLASKIRLLLMDVDGVLTDGKLYNVPGPDGKMAETKGFDSQDGIALQWMARLGI
CCCCHHHHHHHHHHHEECCCCEEECCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
ATGLISGRVSPATVERAHQCKFKYIYQGHTEKIPILNEILADAKLDPSEVAYIGDDFTDV
HHHHHCCCCCHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHCCCCCHHHEEEECCCHHHH
VVMRRVGLSFATANARSEMKSIAHYVTATPGGQGAVREVVEVILKAQGKWDEILRHYEVI
HHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
TDPRPAGRDVSLGEA
CCCCCCCCCCCCCCC
>Mature Secondary Structure 
SADVPRLASKIRLLLMDVDGVLTDGKLYNVPGPDGKMAETKGFDSQDGIALQWMARLGI
CCCHHHHHHHHHHHEECCCCEEECCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
ATGLISGRVSPATVERAHQCKFKYIYQGHTEKIPILNEILADAKLDPSEVAYIGDDFTDV
HHHHHCCCCCHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHCCCCCHHHEEEECCCHHHH
VVMRRVGLSFATANARSEMKSIAHYVTATPGGQGAVREVVEVILKAQGKWDEILRHYEVI
HHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
TDPRPAGRDVSLGEA
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]