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The map label for this gene is gph [H]

Identifier: 116626115

GI number: 116626115

Start: 8888780

End: 8889427

Strand: Reverse

Name: gph [H]

Synonym: Acid_7073

Alternate gene names: 116626115

Gene position: 8889427-8888780 (Counterclockwise)

Preceding gene: 116626116

Following gene: 116626113

Centisome position: 89.2

GC content: 60.65

Gene sequence:

>648_bases
GTGATCCCCGCGTTCCCTGTCTACCTGTTTGATATAGACGGCACCCTGCTGGATAGCGCCCAGGATATCTGCGGCGCGGT
CCAGCAGGTGCTGGATACCCACCCATCCCCTTCTGTCTCGTACGAATTCCTCAAGAGCTACATCGGCCGTCACCTTAACG
ATCTCTTCTTGGACATCTGGCCGGAAGCTACTCCCGAACGTCTCGCAGAACTGCTGGCCGAATATCGCAGCTACTATCCG
GCCCGAGGCCACAAGCTGACGTCGATTTATCCGGGCGTGGTGGAAGGACTTTCGGTACTGGGCGGCCGCAAAGGCACCGC
CACTACCAAGGGTACGCCGACCACGCGTGCCATCCTCGAGCAGTTCGGGCTGATTCAATTCTTCGACCACGTGCAAGGCA
CAGATGGATTTCCGTGCAAACCGGCTCCCGATGTGATTTTCACGGCGCTCCAGGCGCTCGGGGCACAGCCGCAAGACTGC
CTGTTCGTGGGCGATTCGCCCGCTGATATGGAGGCGGGTCGCCGCGCGGGCGTGAAGACATGCGCGGTCACCTATGGCTA
CGGCAAGCGCGAAGACCTGGCGATCTTCACCCCCGATTATTGGGTAGACGATCTGCGCTCCTTGAGCGCGCTTGCGGCGA
CAGCTTAG

Upstream 100 bases:

>100_bases
TCGCGCCGCCGGCTCCCAAAGATTCGGGCGACACGCAGCAGGTGCTGCGCCCGGATAGCGGCCGGCGCGTCCCGGGCTTG
AACGAGGGCTCGGCGCCCGC

Downstream 100 bases:

>100_bases
ATCAGACTGTTTTCGTTATGCACGCTGCTGCCGGCGCATCTTGATGTAAAGCAGTCCGAACCCCGCGGCAGTCAACAGCA
CCGTACCAGGCTCGGGGGTG

Product: HAD family hydrolase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MIPAFPVYLFDIDGTLLDSAQDICGAVQQVLDTHPSPSVSYEFLKSYIGRHLNDLFLDIWPEATPERLAELLAEYRSYYP
ARGHKLTSIYPGVVEGLSVLGGRKGTATTKGTPTTRAILEQFGLIQFFDHVQGTDGFPCKPAPDVIFTALQALGAQPQDC
LFVGDSPADMEAGRRAGVKTCAVTYGYGKREDLAIFTPDYWVDDLRSLSALAATA

Sequences:

>Translated_215_residues
MIPAFPVYLFDIDGTLLDSAQDICGAVQQVLDTHPSPSVSYEFLKSYIGRHLNDLFLDIWPEATPERLAELLAEYRSYYP
ARGHKLTSIYPGVVEGLSVLGGRKGTATTKGTPTTRAILEQFGLIQFFDHVQGTDGFPCKPAPDVIFTALQALGAQPQDC
LFVGDSPADMEAGRRAGVKTCAVTYGYGKREDLAIFTPDYWVDDLRSLSALAATA
>Mature_215_residues
MIPAFPVYLFDIDGTLLDSAQDICGAVQQVLDTHPSPSVSYEFLKSYIGRHLNDLFLDIWPEATPERLAELLAEYRSYYP
ARGHKLTSIYPGVVEGLSVLGGRKGTATTKGTPTTRAILEQFGLIQFFDHVQGTDGFPCKPAPDVIFTALQALGAQPQDC
LFVGDSPADMEAGRRAGVKTCAVTYGYGKREDLAIFTPDYWVDDLRSLSALAATA

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=224, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 23413; Mature: 23413

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPAFPVYLFDIDGTLLDSAQDICGAVQQVLDTHPSPSVSYEFLKSYIGRHLNDLFLDIW
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHC
PEATPERLAELLAEYRSYYPARGHKLTSIYPGVVEGLSVLGGRKGTATTKGTPTTRAILE
CCCCHHHHHHHHHHHHHCCCCCCCCCHHCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
QFGLIQFFDHVQGTDGFPCKPAPDVIFTALQALGAQPQDCLFVGDSPADMEAGRRAGVKT
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHCCCCE
CAVTYGYGKREDLAIFTPDYWVDDLRSLSALAATA
EEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIPAFPVYLFDIDGTLLDSAQDICGAVQQVLDTHPSPSVSYEFLKSYIGRHLNDLFLDIW
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHC
PEATPERLAELLAEYRSYYPARGHKLTSIYPGVVEGLSVLGGRKGTATTKGTPTTRAILE
CCCCHHHHHHHHHHHHHCCCCCCCCCHHCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
QFGLIQFFDHVQGTDGFPCKPAPDVIFTALQALGAQPQDCLFVGDSPADMEAGRRAGVKT
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHCCCCE
CAVTYGYGKREDLAIFTPDYWVDDLRSLSALAATA
EEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA