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The map label for this gene is cocE [H]

Identifier: 116626109

GI number: 116626109

Start: 8883149

End: 8884954

Strand: Direct

Name: cocE [H]

Synonym: Acid_7067

Alternate gene names: 116626109

Gene position: 8883149-8884954 (Clockwise)

Preceding gene: 116626105

Following gene: 116626114

Centisome position: 89.14

GC content: 63.07

Gene sequence:

>1806_bases
ATGAAACGCGCGATCCTCCTCGGCCTGCTGGCCGGAATCCTGCTGCGGGCCAGTCCCCAGGATAACGAGCCCCGCGTCTA
TGTCGATTACCGCCTGGTCATGATCCCCATGCGCGACGGCGTACGGTTGGAGACCGTGATCCTGACGCCGAAGGGCGCCC
ACGGGCCTCTGCCTTTCCTGATCGACCGCACGCCCTACGGCGTCCCCGCCGAGGACACGGTCGCCAAGGGCTTTCCCGCT
CGCCAGCGCTGGCGCGCCGAGAATTACATCTTCGTCTCGCAGAACATTCGCGGGCGTTTTCAGAGCGAAGGCAAATTTGT
GATGTTTCACCCACCGCACGATCCCAAAGACGCCAAGGGCATCGATGAGACCACCGACGCCTGGGATACGGTGGACTGGC
TGATCAAGAACGTGTCCAACAACAACGGCCGCGCCGGTATCGCCGGGACATCCTACGACGGATGGACGGCCGTGATGGCT
GCGCTCAACCCGCACCCCGCGCTCAAAGCCGCGATCGAACAGGCCTCGCCCGCCGACCAGTTCCTGGGCGACGACTTCCA
TCACAACGGCGCCTTCCGCCTCAGCTACGGCTTCGAATATTCCGCCATGCTCGAGACCGCGTCCACCGAAAACTACCGCT
TCCAGTTCGACCGCGCCGATACCTATGATTGGTACCTCGGCCTGGGCCCGCTCACCAACGCCGACGAGAAGTATTTCCAC
GGCAAGGTGCCCACCTGGACGGACTTCATGCGCCATCCCAATTACGACGCCTTCTGGCAGCGCCAGGCCTTCGCGCCGTA
CCTGAACTCCGTGAAGATCCCGATCGTGCACACCGCCGGATGGTGGGACCAGGAGGATTTCTACGGCCCGCAGAAAATCT
ACGAACTGCTGGAGCGCAACGACCCGGAGCACCGTAATTATTTCGTCGCGGGCCCATGGAACCACGGCGGATGGAACGGC
AACGGCAGCAAACTTGGAAGCGTCGAGTTCGGCGGAGACACCGCGCTGCACTATCGCGAGACCATTTTCCAACCCTGGTT
CGACTACTGGCTGCGCGGCGAGGGCGAGTTGAAACTGGCCGAGGCCACCGTCTTCGAAACCGGTGCGAACCGCTGGCAGG
AGCACGAGGCCTGGCCGCCCAAGCGCGCCGTGGAGCCGCGCCGCCTTTACTTCCGCGAGGGCGGAAAGCTTGAGTTCACT
GGACCCGGCCCGTCCGGCGCGTTCGACGAGTACGTCAGCGACCCCGCCAACCCCGTGCCCTATCGTCCACGCCCAGTTCC
GGCCACCTATCCTGGGAATGATTGGCGCGTCTGGCTGGTGCAGGATCAGCGCTTCGTGGACCATCGGCCCGATGTGCTCA
CCTGGCAGACCGGGCCGCTCAAGGAAGACCTGCGCATCGCCGGTGACCTGCTGACCGAACTCGTAGCCTCGACCACCGGC
ACCGATAGCGACTGGGTGGTGAAGCTGATCGACGTCTATCCGGAGAATGCGAAGGACCTACCTGGCTATCAGCTCATGAT
CGCCGATGAGATCTTGCGTGCACGCTTCCGCAACGGCTTCGAGAAGCCCGAGCCCGTGCCCGCCGGAAAGCCGGTGAAGT
ATACGATCGACCTGCACACCAACGCGCACTCCTTCCTGAAAGGCCATCGCATCATGGTGCAGGTGCAAAGCACCTGGTTC
CCCGTCTACGACCGTAATCCGCAGAAGTTCGTGCCGAATATCTTTGAGGCGCACGCCGGCGATTACGTGAAGGCCACGCA
GCGCATCTACCGAGGCAGCGCCATCGTGCTACCGGTGCTCAAGTAA

Upstream 100 bases:

>100_bases
AGAAAATTACGCCGATTCAATTCGTCCGCCATGGGACCTCCAGTTTCTGATATTCCGATCATAGCAGCGGGCGGTATGAT
CGGGAGCAATGGAGAAGCCC

Downstream 100 bases:

>100_bases
GTTTCCACGGTTTCCGGTACTGCCGGGTCACGTAGCGATTGGCCTGCGTGCGCCCAGTGAAATGTTCGTGGGCGTCGTCC
CAGTGGAGTCGCTCGCCGGT

Product: X-Pro dipeptidyl-peptidase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 601; Mature: 601

Protein sequence:

>601_residues
MKRAILLGLLAGILLRASPQDNEPRVYVDYRLVMIPMRDGVRLETVILTPKGAHGPLPFLIDRTPYGVPAEDTVAKGFPA
RQRWRAENYIFVSQNIRGRFQSEGKFVMFHPPHDPKDAKGIDETTDAWDTVDWLIKNVSNNNGRAGIAGTSYDGWTAVMA
ALNPHPALKAAIEQASPADQFLGDDFHHNGAFRLSYGFEYSAMLETASTENYRFQFDRADTYDWYLGLGPLTNADEKYFH
GKVPTWTDFMRHPNYDAFWQRQAFAPYLNSVKIPIVHTAGWWDQEDFYGPQKIYELLERNDPEHRNYFVAGPWNHGGWNG
NGSKLGSVEFGGDTALHYRETIFQPWFDYWLRGEGELKLAEATVFETGANRWQEHEAWPPKRAVEPRRLYFREGGKLEFT
GPGPSGAFDEYVSDPANPVPYRPRPVPATYPGNDWRVWLVQDQRFVDHRPDVLTWQTGPLKEDLRIAGDLLTELVASTTG
TDSDWVVKLIDVYPENAKDLPGYQLMIADEILRARFRNGFEKPEPVPAGKPVKYTIDLHTNAHSFLKGHRIMVQVQSTWF
PVYDRNPQKFVPNIFEAHAGDYVKATQRIYRGSAIVLPVLK

Sequences:

>Translated_601_residues
MKRAILLGLLAGILLRASPQDNEPRVYVDYRLVMIPMRDGVRLETVILTPKGAHGPLPFLIDRTPYGVPAEDTVAKGFPA
RQRWRAENYIFVSQNIRGRFQSEGKFVMFHPPHDPKDAKGIDETTDAWDTVDWLIKNVSNNNGRAGIAGTSYDGWTAVMA
ALNPHPALKAAIEQASPADQFLGDDFHHNGAFRLSYGFEYSAMLETASTENYRFQFDRADTYDWYLGLGPLTNADEKYFH
GKVPTWTDFMRHPNYDAFWQRQAFAPYLNSVKIPIVHTAGWWDQEDFYGPQKIYELLERNDPEHRNYFVAGPWNHGGWNG
NGSKLGSVEFGGDTALHYRETIFQPWFDYWLRGEGELKLAEATVFETGANRWQEHEAWPPKRAVEPRRLYFREGGKLEFT
GPGPSGAFDEYVSDPANPVPYRPRPVPATYPGNDWRVWLVQDQRFVDHRPDVLTWQTGPLKEDLRIAGDLLTELVASTTG
TDSDWVVKLIDVYPENAKDLPGYQLMIADEILRARFRNGFEKPEPVPAGKPVKYTIDLHTNAHSFLKGHRIMVQVQSTWF
PVYDRNPQKFVPNIFEAHAGDYVKATQRIYRGSAIVLPVLK
>Mature_601_residues
MKRAILLGLLAGILLRASPQDNEPRVYVDYRLVMIPMRDGVRLETVILTPKGAHGPLPFLIDRTPYGVPAEDTVAKGFPA
RQRWRAENYIFVSQNIRGRFQSEGKFVMFHPPHDPKDAKGIDETTDAWDTVDWLIKNVSNNNGRAGIAGTSYDGWTAVMA
ALNPHPALKAAIEQASPADQFLGDDFHHNGAFRLSYGFEYSAMLETASTENYRFQFDRADTYDWYLGLGPLTNADEKYFH
GKVPTWTDFMRHPNYDAFWQRQAFAPYLNSVKIPIVHTAGWWDQEDFYGPQKIYELLERNDPEHRNYFVAGPWNHGGWNG
NGSKLGSVEFGGDTALHYRETIFQPWFDYWLRGEGELKLAEATVFETGANRWQEHEAWPPKRAVEPRRLYFREGGKLEFT
GPGPSGAFDEYVSDPANPVPYRPRPVPATYPGNDWRVWLVQDQRFVDHRPDVLTWQTGPLKEDLRIAGDLLTELVASTTG
TDSDWVVKLIDVYPENAKDLPGYQLMIADEILRARFRNGFEKPEPVPAGKPVKYTIDLHTNAHSFLKGHRIMVQVQSTWF
PVYDRNPQKFVPNIFEAHAGDYVKATQRIYRGSAIVLPVLK

Specific function: Hydrolyzes cocaine to benzoate and ecgonine methyl ester, endowing the bacteria with the ability to utilize cocaine as a sole source of carbon and energy for growth, as this bacterium lives in the rhizosphere of coca plants [H]

COG id: COG2936

COG function: function code R; Predicted acyl esterases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alpha/beta hydrolase family. Carboxylesterase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005674
- InterPro:   IPR008979
- InterPro:   IPR013736
- InterPro:   IPR000383 [H]

Pfam domain/function: PF02129 Peptidase_S15; PF08530 PepX_C [H]

EC number: NA

Molecular weight: Translated: 68650; Mature: 68650

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRAILLGLLAGILLRASPQDNEPRVYVDYRLVMIPMRDGVRLETVILTPKGAHGPLPFL
CCHHHHHHHHHHHHEECCCCCCCCEEEEEEEEEEEECCCCCEEEEEEEECCCCCCCCCEE
IDRTPYGVPAEDTVAKGFPARQRWRAENYIFVSQNIRGRFQSEGKFVMFHPPHDPKDAKG
ECCCCCCCCCCCHHHCCCCHHHHHCCCCEEEEECCCCCCCCCCCCEEEECCCCCCCCCCC
IDETTDAWDTVDWLIKNVSNNNGRAGIAGTSYDGWTAVMAALNPHPALKAAIEQASPADQ
CCCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHCCCCHHHHHHHHHCCCHHH
FLGDDFHHNGAFRLSYGFEYSAMLETASTENYRFQFDRADTYDWYLGLGPLTNADEKYFH
HCCCCCCCCCEEEEEECCCEEHEEECCCCCCEEEEECCCCCCEEEEECCCCCCCCCCEEC
GKVPTWTDFMRHPNYDAFWQRQAFAPYLNSVKIPIVHTAGWWDQEDFYGPQKIYELLERN
CCCCCHHHHHHCCCCCHHHHHHHHHHHHCCEEEEEEEECCCCCCHHCCCHHHHHHHHHCC
DPEHRNYFVAGPWNHGGWNGNGSKLGSVEFGGDTALHYRETIFQPWFDYWLRGEGELKLA
CCCCCCEEEECCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEE
EATVFETGANRWQEHEAWPPKRAVEPRRLYFREGGKLEFTGPGPSGAFDEYVSDPANPVP
EEEEEHHCCHHHHHCCCCCCHHCCCHHHHHEECCCEEEECCCCCCCCHHHHHCCCCCCCC
YRPRPVPATYPGNDWRVWLVQDQRFVDHRPDVLTWQTGPLKEDLRIAGDLLTELVASTTG
CCCCCCCCCCCCCCEEEEEEECCCHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCC
TDSDWVVKLIDVYPENAKDLPGYQLMIADEILRARFRNGFEKPEPVPAGKPVKYTIDLHT
CCCHHEEEEEECCCCCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEC
NAHSFLKGHRIMVQVQSTWFPVYDRNPQKFVPNIFEAHAGDYVKATQRIYRGSAIVLPVL
CHHHHHCCCEEEEEEECCEEEEECCCHHHHCCHHHHHCCCCHHHHHHHHHCCCEEEEEEC
K
C
>Mature Secondary Structure
MKRAILLGLLAGILLRASPQDNEPRVYVDYRLVMIPMRDGVRLETVILTPKGAHGPLPFL
CCHHHHHHHHHHHHEECCCCCCCCEEEEEEEEEEEECCCCCEEEEEEEECCCCCCCCCEE
IDRTPYGVPAEDTVAKGFPARQRWRAENYIFVSQNIRGRFQSEGKFVMFHPPHDPKDAKG
ECCCCCCCCCCCHHHCCCCHHHHHCCCCEEEEECCCCCCCCCCCCEEEECCCCCCCCCCC
IDETTDAWDTVDWLIKNVSNNNGRAGIAGTSYDGWTAVMAALNPHPALKAAIEQASPADQ
CCCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHCCCCHHHHHHHHHCCCHHH
FLGDDFHHNGAFRLSYGFEYSAMLETASTENYRFQFDRADTYDWYLGLGPLTNADEKYFH
HCCCCCCCCCEEEEEECCCEEHEEECCCCCCEEEEECCCCCCEEEEECCCCCCCCCCEEC
GKVPTWTDFMRHPNYDAFWQRQAFAPYLNSVKIPIVHTAGWWDQEDFYGPQKIYELLERN
CCCCCHHHHHHCCCCCHHHHHHHHHHHHCCEEEEEEEECCCCCCHHCCCHHHHHHHHHCC
DPEHRNYFVAGPWNHGGWNGNGSKLGSVEFGGDTALHYRETIFQPWFDYWLRGEGELKLA
CCCCCCEEEECCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEE
EATVFETGANRWQEHEAWPPKRAVEPRRLYFREGGKLEFTGPGPSGAFDEYVSDPANPVP
EEEEEHHCCHHHHHCCCCCCHHCCCHHHHHEECCCEEEECCCCCCCCHHHHHCCCCCCCC
YRPRPVPATYPGNDWRVWLVQDQRFVDHRPDVLTWQTGPLKEDLRIAGDLLTELVASTTG
CCCCCCCCCCCCCCEEEEEEECCCHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCC
TDSDWVVKLIDVYPENAKDLPGYQLMIADEILRARFRNGFEKPEPVPAGKPVKYTIDLHT
CCCHHEEEEEECCCCCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEC
NAHSFLKGHRIMVQVQSTWFPVYDRNPQKFVPNIFEAHAGDYVKATQRIYRGSAIVLPVL
CHHHHHCCCEEEEEEECCEEEEECCCHHHHCCHHHHHCCCCHHHHHHHHHCCCEEEEEEC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10698749; 11742345; 12369817 [H]