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The map label for this gene is iolG [H]

Identifier: 116626050

GI number: 116626050

Start: 8807787

End: 8809124

Strand: Reverse

Name: iolG [H]

Synonym: Acid_7008

Alternate gene names: 116626050

Gene position: 8809124-8807787 (Counterclockwise)

Preceding gene: 116626052

Following gene: 116626049

Centisome position: 88.39

GC content: 65.99

Gene sequence:

>1338_bases
ATGCCGACGCGTCGCGCCGCGCTCGGCGCCCTGACCGCCTTCTCCTACAATCGAATCCTCGGCGCCAACGACCGCGTTCA
GGTCGGCTTCATCGGCTACGGCCTCATCGGCGGCCAGCACGTCTTCGATTTCAAGAACCAGAAGGACGCCGACCTCGCCG
CCATGTGCGACGTCTATCAGCCCCGCCTGGAACAAGGCGTCGCCGCCTGCGGCCAGACCGCCAAGCCCTATTCCGATTTC
CGCAAGCTCCTTGAGAACCGCGACCTGCAGGCTGTCATCGTCTGCACACCCGATCACTGGCACGCCCTCATGACCATGAT
GGCCTGCGCCGCCGGCAAGGACGTCTACGTCGAGAAGCCCCTCACCGTCTTCATCCGCGAAGGCCGCTGGATGACCAGCG
TCGCCCGCCGCCACAATCGCGTCGTGCAGGTCGGCACCCAGCAGCGCTCCGGCCGCCATTACCAGCACGCCCGCGACCTC
CTGCAATCCGGCTACATCGGCCAGATCATGAGCATGCGCGCCGCGTCCTATCGCAACATCATGCCCGGCTTTGGCTCGCC
GCCCGACACCGCCGCGCCCCACGAATTCGATTACGATATGTGGCTCGGCCCCGCGCCCGCGCGCCCCTACAACAAGCAGC
GCGGCATTTATCATTTCCGCTGGTTTTGGGACTACTCCGGCGGCCAGATGACCAATCTCGGCGCCCACGAAATCGACATC
ATGCAGTGGGTCATGAACGTCAAGGGCCCTACCGCCGTCTCCTCCAGCGGCGGCCGCTTCGCCATCAAGGATCTCGGTGA
GACTCCCGACACTCAGGACGCCACCTTCGAATACCCTGGCTTCACCGCCGCCTACGGATTCCGCGAAGCCTCCGCCGGAC
GCCGCGCGGGCGCCGGCCTCGAATTCTTCGGCACCAAGGGCAGCCTGCTCATCAGCCGCTCCGGCTTCGAAGTCTTCCCC
GACATGAAGGCCAACCCCGCCAACGCCATCCCCGTCTTCCAGGGACAACCCGCCGGCGGCCCCGAGCTCGTCACCGCAAA
GCCTGAACCTTGGATCGAGGCGATCAAGGAGCCCGGATCCTCCGCCGAGCAGTTCGACCTGCACGCACGCAACTTCCTCG
ATTGCGTCAAGTCCCGCCGGCGCCCCATCGCTGATGTCGAAGGCGGCCACCAGGTCACCACCGCCTGCCACCTCGCCAAC
CTCTCCCTCCGCCTCGGCCGCAAACTCAAATGGGACCCCGAGCGTGAAGAAATCTCCGGCGACCGCGAAGCCACCGCCAT
GCTCGAACGCCCCTACCGCAAACCCTGGGACGCAGTCCTCCGAGGCCTCCTCGCATGA

Upstream 100 bases:

>100_bases
GGCCGCCGCAACGAACAAGTATTCCCCCAACTAATGGGATACGTGTGCCCGCGCGATATACTGGCAGCAATCCTGCAAGG
AGGCATTCGTGAACGCATCC

Downstream 100 bases:

>100_bases
TCTCTGTACTACTGTGCATCTGTCTGTGTGGGGCAGGCAATCTTGCCTGCAGCCGCCTTTCAGGCGGGCTTCTCCGCTCA
CGCGCGCCCCTTATCGCAAC

Product: oxidoreductase domain-containing protein

Products: NA

Alternate protein names: Myo-inositol 2-dehydrogenase; MI 2-dehydrogenase [H]

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MPTRRAALGALTAFSYNRILGANDRVQVGFIGYGLIGGQHVFDFKNQKDADLAAMCDVYQPRLEQGVAACGQTAKPYSDF
RKLLENRDLQAVIVCTPDHWHALMTMMACAAGKDVYVEKPLTVFIREGRWMTSVARRHNRVVQVGTQQRSGRHYQHARDL
LQSGYIGQIMSMRAASYRNIMPGFGSPPDTAAPHEFDYDMWLGPAPARPYNKQRGIYHFRWFWDYSGGQMTNLGAHEIDI
MQWVMNVKGPTAVSSSGGRFAIKDLGETPDTQDATFEYPGFTAAYGFREASAGRRAGAGLEFFGTKGSLLISRSGFEVFP
DMKANPANAIPVFQGQPAGGPELVTAKPEPWIEAIKEPGSSAEQFDLHARNFLDCVKSRRRPIADVEGGHQVTTACHLAN
LSLRLGRKLKWDPEREEISGDREATAMLERPYRKPWDAVLRGLLA

Sequences:

>Translated_445_residues
MPTRRAALGALTAFSYNRILGANDRVQVGFIGYGLIGGQHVFDFKNQKDADLAAMCDVYQPRLEQGVAACGQTAKPYSDF
RKLLENRDLQAVIVCTPDHWHALMTMMACAAGKDVYVEKPLTVFIREGRWMTSVARRHNRVVQVGTQQRSGRHYQHARDL
LQSGYIGQIMSMRAASYRNIMPGFGSPPDTAAPHEFDYDMWLGPAPARPYNKQRGIYHFRWFWDYSGGQMTNLGAHEIDI
MQWVMNVKGPTAVSSSGGRFAIKDLGETPDTQDATFEYPGFTAAYGFREASAGRRAGAGLEFFGTKGSLLISRSGFEVFP
DMKANPANAIPVFQGQPAGGPELVTAKPEPWIEAIKEPGSSAEQFDLHARNFLDCVKSRRRPIADVEGGHQVTTACHLAN
LSLRLGRKLKWDPEREEISGDREATAMLERPYRKPWDAVLRGLLA
>Mature_444_residues
PTRRAALGALTAFSYNRILGANDRVQVGFIGYGLIGGQHVFDFKNQKDADLAAMCDVYQPRLEQGVAACGQTAKPYSDFR
KLLENRDLQAVIVCTPDHWHALMTMMACAAGKDVYVEKPLTVFIREGRWMTSVARRHNRVVQVGTQQRSGRHYQHARDLL
QSGYIGQIMSMRAASYRNIMPGFGSPPDTAAPHEFDYDMWLGPAPARPYNKQRGIYHFRWFWDYSGGQMTNLGAHEIDIM
QWVMNVKGPTAVSSSGGRFAIKDLGETPDTQDATFEYPGFTAAYGFREASAGRRAGAGLEFFGTKGSLLISRSGFEVFPD
MKANPANAIPVFQGQPAGGPELVTAKPEPWIEAIKEPGSSAEQFDLHARNFLDCVKSRRRPIADVEGGHQVTTACHLANL
SLRLGRKLKWDPEREEISGDREATAMLERPYRKPWDAVLRGLLA

Specific function: Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) [H]

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.1.18 [H]

Molecular weight: Translated: 49492; Mature: 49361

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTRRAALGALTAFSYNRILGANDRVQVGFIGYGLIGGQHVFDFKNQKDADLAAMCDVYQ
CCCHHHHHHHHHHHHHHHEECCCCCEEEEEEEEEEECCCEEECCCCCCCCHHHHHHHHHH
PRLEQGVAACGQTAKPYSDFRKLLENRDLQAVIVCTPDHWHALMTMMACAAGKDVYVEKP
HHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEECC
LTVFIREGRWMTSVARRHNRVVQVGTQQRSGRHYQHARDLLQSGYIGQIMSMRAASYRNI
EEEEEECCCHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHC
MPGFGSPPDTAAPHEFDYDMWLGPAPARPYNKQRGIYHFRWFWDYSGGQMTNLGAHEIDI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCEEECCCCHHHHH
MQWVMNVKGPTAVSSSGGRFAIKDLGETPDTQDATFEYPGFTAAYGFREASAGRRAGAGL
HHHHHHCCCCCEECCCCCEEEEEECCCCCCCCCCEEECCCCCHHHCCHHHCCCCCCCCCE
EFFGTKGSLLISRSGFEVFPDMKANPANAIPVFQGQPAGGPELVTAKPEPWIEAIKEPGS
EEECCCCCEEEECCCCEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHCCCC
SAEQFDLHARNFLDCVKSRRRPIADVEGGHQVTTACHLANLSLRLGRKLKWDPEREEISG
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCCCCHHHHCC
DREATAMLERPYRKPWDAVLRGLLA
CHHHHHHHHCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
PTRRAALGALTAFSYNRILGANDRVQVGFIGYGLIGGQHVFDFKNQKDADLAAMCDVYQ
CCHHHHHHHHHHHHHHHEECCCCCEEEEEEEEEEECCCEEECCCCCCCCHHHHHHHHHH
PRLEQGVAACGQTAKPYSDFRKLLENRDLQAVIVCTPDHWHALMTMMACAAGKDVYVEKP
HHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEECC
LTVFIREGRWMTSVARRHNRVVQVGTQQRSGRHYQHARDLLQSGYIGQIMSMRAASYRNI
EEEEEECCCHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHC
MPGFGSPPDTAAPHEFDYDMWLGPAPARPYNKQRGIYHFRWFWDYSGGQMTNLGAHEIDI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCEEECCCCHHHHH
MQWVMNVKGPTAVSSSGGRFAIKDLGETPDTQDATFEYPGFTAAYGFREASAGRRAGAGL
HHHHHHCCCCCEECCCCCEEEEEECCCCCCCCCCEEECCCCCHHHCCHHHCCCCCCCCCE
EFFGTKGSLLISRSGFEVFPDMKANPANAIPVFQGQPAGGPELVTAKPEPWIEAIKEPGS
EEECCCCCEEEECCCCEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHCCCC
SAEQFDLHARNFLDCVKSRRRPIADVEGGHQVTTACHLANLSLRLGRKLKWDPEREEISG
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCCCCHHHHCC
DREATAMLERPYRKPWDAVLRGLLA
CHHHHHHHHCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA