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The map label for this gene is macB [H]

Identifier: 116626043

GI number: 116626043

Start: 8794979

End: 8797234

Strand: Direct

Name: macB [H]

Synonym: Acid_7001

Alternate gene names: 116626043

Gene position: 8794979-8797234 (Clockwise)

Preceding gene: 116626042

Following gene: 116626044

Centisome position: 88.25

GC content: 68.57

Gene sequence:

>2256_bases
ATGCTGACCGATCTCCGCCACGCCGTTCGCGGCCTTCGTAAAGCCCCAGCGCTCTCCGCGGTCGCGATCGCGTCCCTCGC
CCTCGGAATCGGCGCCAACGTCACCGCCTTTAGCGTCGCGCGCGAAATGATCTTCAACGATATCAGCGCCGTACAGCCCG
GTCGCCTCGCACGCATCGACACCGGCGTGACCTATACGCGCTACCAGGAACTGCGCGCCGCCGGAGTCTTCCAGGACCTC
GCCTTCGACTCTGGTTTTCACGATGCCGTATGGCAGCGCACCGGCCGCAATGAAGTCGTCTGGGTCATGGACACCAGCCC
CAACTTCTTCGAGGTGCTTCGCATTCATCCGGCTGCCGGACGCCTCTACACGCAGCACGACGAAGGCTTCCCGGTTGCGG
TCGTGAGCCACGGCTTCTGGCGCAAGCGCCTCGCCTCAGACCCCGCCGCGCTCGGTCGCACCCTGCAGGTGAACGGGCGC
CCGTACACTGTGGTCGGCGTGCTGCCGCCCGCATATCGCAGCGTGATGGGCCACAGCGTCGCGCCCGAAATCTATGCGCC
GGCGCGCTTGGATTCACAGCAGCGATGCCGTCCCTTCGGCCGCCTGCGCGACGGCATGACGCGTGAGCAGGCCCGCCAGT
CGCTAACTGGCGTTGCCAAGGAACCACCGGCGGTCCGCCCGCTCAGCGGCTTCTATTTCGGCCAGGGAGGCGACGACTAC
CGGATGTTCGTCTTCTTCCTGATGCTGCTCGGCATCGCCATGATCCTCGCCCTGATCGCTTGTTCCAACGTGGCCGGACT
CCTGCTCGCGCGCCGCGCCGCCCGCTTTCGCGAGATGACCATTCGCCAGGCCCTGGGCGCCAATCGCTGGCAGCTCGCCC
GCCCGCTGCTCGGCGAAGCGCTCGTGCTGGTCGCCTGCGGCGCCGCCTCCGGGCTCGCGCTCGATGCGTGGCTGCGCAGC
CACCTGCGCTACCTGCGGTGGCCCACCGCCTACAACATTCCCCTCGAGTTTCATTTCGAAAGCGACCACAGCCTCTTCCT
CTACGCGCTGCTTACGGCATGCGCCGCGCTGCTGGTCTGCTCCCCCACCGGAGCCGTCAAACCGCCTTCCACTCGTTGGA
ACCTGCGCAGCGGTTTCGTCGGCCTGCAAGTCGTGCTCTCCATGGTGCTGCTCACGCTCGGCGCGCTCTTCGCCCGGAGC
TTCCTGCACGTAGCCAACCTGGATGTTGGCTTCGATGCCGTCCACACCGTGATCGCCGCCGTCCATCCGCTGCCTCGCGC
GGAGCACGCGTGGGCGTGGCGCCAGCGCCTCGCCGATGCGATTCGCCGCGTTCCCGGCGTCGAGGCCGTCACCTCCACGG
ACCTGCTGCCGCTGATGGGTGAAGTCCATGACGCTCCGCTGCGCCGCGCGGGCGAGCCAGTTTCCGCCGCGCGCGAGATC
TACTCCATGGCCGAAGGCGAGCAGTACTTCAGGACTCTCCGCATCCCCATCCTGCGCGGCCGCGATTTCGAGATCGCCGA
TCGCGATCGAAATCCCACGCCGGCCATCATCAACCGCACGCTGGCCCTGCAACTTTTCCCTGGCGCCGACCCGGTCGGCC
AGCACCTGATCCGCGGACGCGAGAAGGAAGAGGTGCTGGAAATCATCGGCATCGCTGCCGATACTAAGATGCGTACGCTC
GGGGAAGCCGCCACTCCTGCCGTTTACACGCCCGATTACAACGGCCAGTTCCTCATCCGCGTTGCCGGCGACCCCGCGCA
ATGGGTCGAGCCCCTGCGCCGCGCGCTCGCCGCTTCCGACCCGGCGCCGGCGCTCGACATCCGCCCCCTGCGCGACGCCG
TCGCGGGCGCGCTCTTCCCCATGCGGATGGCGGCCGCCTTCGTCACTTCAATCGGCGGCATCGGCCTCGTGCTCGCGCTG
GTCGGCGTGTACGGGTCAGTCTCCTACGCGGTCAGCCGCCGCACCCGCGAGTTCGGCATCCGCGCCGCGCTCGGCGCCAC
CCGCGCGCGCATCCTGTGGACCGCCCTCCGCGATGGCGCGCTCCTCCTCATCGCCGGCTCCATTGCCGGCCTGCTGCTCG
CGATTTCCGCGATTCGTCCCGTGGTCGATCTTCTGCCCGATGGCATCGACCCGTGGGACCCGCGCCTCTTCGCCGCCGCT
GCCGTCGCCCTGATCGCTTCCGGCATCGCCGGCGCCGCTCTACCCGCCCGCCGCGCCGCCCAAGTCGATTGCACCGCCGC
TTTGCGTGAGGAGTAG

Upstream 100 bases:

>100_bases
ACGAACAGAACGCACCGGCCGCAGCCTCCGTCGCCGCATATTACAAAACCATTCCCTGAATCTCCACGCTTTTTCCCTTC
TGCATGTCATCCTCTTCTAG

Downstream 100 bases:

>100_bases
CGCCCGCGTTCGCTGCCCTCCTTCCGCGCCTGGCCCGCGATTTTCCGCGCTCGCCAGCCGCGCCCTGGACTCACCCCACC
CGGCATCGTTATCCTTGTGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 751; Mature: 751

Protein sequence:

>751_residues
MLTDLRHAVRGLRKAPALSAVAIASLALGIGANVTAFSVAREMIFNDISAVQPGRLARIDTGVTYTRYQELRAAGVFQDL
AFDSGFHDAVWQRTGRNEVVWVMDTSPNFFEVLRIHPAAGRLYTQHDEGFPVAVVSHGFWRKRLASDPAALGRTLQVNGR
PYTVVGVLPPAYRSVMGHSVAPEIYAPARLDSQQRCRPFGRLRDGMTREQARQSLTGVAKEPPAVRPLSGFYFGQGGDDY
RMFVFFLMLLGIAMILALIACSNVAGLLLARRAARFREMTIRQALGANRWQLARPLLGEALVLVACGAASGLALDAWLRS
HLRYLRWPTAYNIPLEFHFESDHSLFLYALLTACAALLVCSPTGAVKPPSTRWNLRSGFVGLQVVLSMVLLTLGALFARS
FLHVANLDVGFDAVHTVIAAVHPLPRAEHAWAWRQRLADAIRRVPGVEAVTSTDLLPLMGEVHDAPLRRAGEPVSAAREI
YSMAEGEQYFRTLRIPILRGRDFEIADRDRNPTPAIINRTLALQLFPGADPVGQHLIRGREKEEVLEIIGIAADTKMRTL
GEAATPAVYTPDYNGQFLIRVAGDPAQWVEPLRRALAASDPAPALDIRPLRDAVAGALFPMRMAAAFVTSIGGIGLVLAL
VGVYGSVSYAVSRRTREFGIRAALGATRARILWTALRDGALLLIAGSIAGLLLAISAIRPVVDLLPDGIDPWDPRLFAAA
AVALIASGIAGAALPARRAAQVDCTAALREE

Sequences:

>Translated_751_residues
MLTDLRHAVRGLRKAPALSAVAIASLALGIGANVTAFSVAREMIFNDISAVQPGRLARIDTGVTYTRYQELRAAGVFQDL
AFDSGFHDAVWQRTGRNEVVWVMDTSPNFFEVLRIHPAAGRLYTQHDEGFPVAVVSHGFWRKRLASDPAALGRTLQVNGR
PYTVVGVLPPAYRSVMGHSVAPEIYAPARLDSQQRCRPFGRLRDGMTREQARQSLTGVAKEPPAVRPLSGFYFGQGGDDY
RMFVFFLMLLGIAMILALIACSNVAGLLLARRAARFREMTIRQALGANRWQLARPLLGEALVLVACGAASGLALDAWLRS
HLRYLRWPTAYNIPLEFHFESDHSLFLYALLTACAALLVCSPTGAVKPPSTRWNLRSGFVGLQVVLSMVLLTLGALFARS
FLHVANLDVGFDAVHTVIAAVHPLPRAEHAWAWRQRLADAIRRVPGVEAVTSTDLLPLMGEVHDAPLRRAGEPVSAAREI
YSMAEGEQYFRTLRIPILRGRDFEIADRDRNPTPAIINRTLALQLFPGADPVGQHLIRGREKEEVLEIIGIAADTKMRTL
GEAATPAVYTPDYNGQFLIRVAGDPAQWVEPLRRALAASDPAPALDIRPLRDAVAGALFPMRMAAAFVTSIGGIGLVLAL
VGVYGSVSYAVSRRTREFGIRAALGATRARILWTALRDGALLLIAGSIAGLLLAISAIRPVVDLLPDGIDPWDPRLFAAA
AVALIASGIAGAALPARRAAQVDCTAALREE
>Mature_751_residues
MLTDLRHAVRGLRKAPALSAVAIASLALGIGANVTAFSVAREMIFNDISAVQPGRLARIDTGVTYTRYQELRAAGVFQDL
AFDSGFHDAVWQRTGRNEVVWVMDTSPNFFEVLRIHPAAGRLYTQHDEGFPVAVVSHGFWRKRLASDPAALGRTLQVNGR
PYTVVGVLPPAYRSVMGHSVAPEIYAPARLDSQQRCRPFGRLRDGMTREQARQSLTGVAKEPPAVRPLSGFYFGQGGDDY
RMFVFFLMLLGIAMILALIACSNVAGLLLARRAARFREMTIRQALGANRWQLARPLLGEALVLVACGAASGLALDAWLRS
HLRYLRWPTAYNIPLEFHFESDHSLFLYALLTACAALLVCSPTGAVKPPSTRWNLRSGFVGLQVVLSMVLLTLGALFARS
FLHVANLDVGFDAVHTVIAAVHPLPRAEHAWAWRQRLADAIRRVPGVEAVTSTDLLPLMGEVHDAPLRRAGEPVSAAREI
YSMAEGEQYFRTLRIPILRGRDFEIADRDRNPTPAIINRTLALQLFPGADPVGQHLIRGREKEEVLEIIGIAADTKMRTL
GEAATPAVYTPDYNGQFLIRVAGDPAQWVEPLRRALAASDPAPALDIRPLRDAVAGALFPMRMAAAFVTSIGGIGLVLAL
VGVYGSVSYAVSRRTREFGIRAALGATRARILWTALRDGALLLIAGSIAGLLLAISAIRPVVDLLPDGIDPWDPRLFAAA
AVALIASGIAGAALPARRAAQVDCTAALREE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 81504; Mature: 81504

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTDLRHAVRGLRKAPALSAVAIASLALGIGANVTAFSVAREMIFNDISAVQPGRLARID
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEC
TGVTYTRYQELRAAGVFQDLAFDSGFHDAVWQRTGRNEVVWVMDTSPNFFEVLRIHPAAG
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEEECCCCCEEHEEECCCCC
RLYTQHDEGFPVAVVSHGFWRKRLASDPAALGRTLQVNGRPYTVVGVLPPAYRSVMGHSV
CEEEECCCCCCEEEECCCHHHHHHCCCHHHCCCEEEECCCCEEEEEECCHHHHHHHCCCC
APEIYAPARLDSQQRCRPFGRLRDGMTREQARQSLTGVAKEPPAVRPLSGFYFGQGGDDY
CCCCCCCCCCCCHHHCCHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHH
RMFVFFLMLLGIAMILALIACSNVAGLLLARRAARFREMTIRQALGANRWQLARPLLGEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LVLVACGAASGLALDAWLRSHLRYLRWPTAYNIPLEFHFESDHSLFLYALLTACAALLVC
HHHHCCCCCCCHHHHHHHHHHHHHHCCCCEECCCEEEEECCCCCHHHHHHHHHHHHHHHC
SPTGAVKPPSTRWNLRSGFVGLQVVLSMVLLTLGALFARSFLHVANLDVGFDAVHTVIAA
CCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
VHPLPRAEHAWAWRQRLADAIRRVPGVEAVTSTDLLPLMGEVHDAPLRRAGEPVSAAREI
HCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHCCHHHHCCCCHHHHHHH
YSMAEGEQYFRTLRIPILRGRDFEIADRDRNPTPAIINRTLALQLFPGADPVGQHLIRGR
HHHHHHHHHHHHHHCEEECCCCCEECCCCCCCCHHHHCCEEEEEEECCCCHHHHHHHCCC
EKEEVLEIIGIAADTKMRTLGEAATPAVYTPDYNGQFLIRVAGDPAQWVEPLRRALAASD
CHHHHHHHHHHCCCCHHHHHCCCCCCCEECCCCCCEEEEEECCCHHHHHHHHHHHHHCCC
PAPALDIRPLRDAVAGALFPMRMAAAFVTSIGGIGLVLALVGVYGSVSYAVSRRTREFGI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAALGATRARILWTALRDGALLLIAGSIAGLLLAISAIRPVVDLLPDGIDPWDPRLFAAA
HHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
AVALIASGIAGAALPARRAAQVDCTAALREE
HHHHHHHCCHHHCCCHHHHCCCHHHHHHCCC
>Mature Secondary Structure
MLTDLRHAVRGLRKAPALSAVAIASLALGIGANVTAFSVAREMIFNDISAVQPGRLARID
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEC
TGVTYTRYQELRAAGVFQDLAFDSGFHDAVWQRTGRNEVVWVMDTSPNFFEVLRIHPAAG
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEEECCCCCEEHEEECCCCC
RLYTQHDEGFPVAVVSHGFWRKRLASDPAALGRTLQVNGRPYTVVGVLPPAYRSVMGHSV
CEEEECCCCCCEEEECCCHHHHHHCCCHHHCCCEEEECCCCEEEEEECCHHHHHHHCCCC
APEIYAPARLDSQQRCRPFGRLRDGMTREQARQSLTGVAKEPPAVRPLSGFYFGQGGDDY
CCCCCCCCCCCCHHHCCHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHH
RMFVFFLMLLGIAMILALIACSNVAGLLLARRAARFREMTIRQALGANRWQLARPLLGEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LVLVACGAASGLALDAWLRSHLRYLRWPTAYNIPLEFHFESDHSLFLYALLTACAALLVC
HHHHCCCCCCCHHHHHHHHHHHHHHCCCCEECCCEEEEECCCCCHHHHHHHHHHHHHHHC
SPTGAVKPPSTRWNLRSGFVGLQVVLSMVLLTLGALFARSFLHVANLDVGFDAVHTVIAA
CCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
VHPLPRAEHAWAWRQRLADAIRRVPGVEAVTSTDLLPLMGEVHDAPLRRAGEPVSAAREI
HCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHCCHHHHCCCCHHHHHHH
YSMAEGEQYFRTLRIPILRGRDFEIADRDRNPTPAIINRTLALQLFPGADPVGQHLIRGR
HHHHHHHHHHHHHHCEEECCCCCEECCCCCCCCHHHHCCEEEEEEECCCCHHHHHHHCCC
EKEEVLEIIGIAADTKMRTLGEAATPAVYTPDYNGQFLIRVAGDPAQWVEPLRRALAASD
CHHHHHHHHHHCCCCHHHHHCCCCCCCEECCCCCCEEEEEECCCHHHHHHHHHHHHHCCC
PAPALDIRPLRDAVAGALFPMRMAAAFVTSIGGIGLVLALVGVYGSVSYAVSRRTREFGI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAALGATRARILWTALRDGALLLIAGSIAGLLLAISAIRPVVDLLPDGIDPWDPRLFAAA
HHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
AVALIASGIAGAALPARRAAQVDCTAALREE
HHHHHHHCCHHHCCCHHHHCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA