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The map label for this gene is hypB [H]

Identifier: 116625974

GI number: 116625974

Start: 8703413

End: 8704099

Strand: Direct

Name: hypB [H]

Synonym: Acid_6932

Alternate gene names: 116625974

Gene position: 8703413-8704099 (Clockwise)

Preceding gene: 116625973

Following gene: 116625975

Centisome position: 87.33

GC content: 61.43

Gene sequence:

>687_bases
ATGAGAATCGACATTGGCGAAAAGGTGCTGCAGGAGAACGCGAAGGTGGCTGCGGAATTGCGCGCCATGCTTACGGAACG
CGGCATCGTCTGCGTGAACCTGATTGGCTCTCCCGGCAGCGGCAAGACGGCGATCCTCGAGCGCACGCTGGCCAACCTGC
GCGAAACGCCATACCACGTGGCGGTCCTGACCGGGGATATCCAGACTGATGCGGACGCCCAACGGCTTTCGCGCTACGGC
TTCCCCGCGCGCCAGATCACCACTGGCGGCGCCTGCCATCTCGACGCACGCATGGTGCTGCGCGGCATGGATGGCTGGGA
CACCGACCAGATCGATCTGCTGTTGATTGAGAACGTCGGCAATCTGGTTTGTCCCACGAGCTACGATCTGGGAGAAGAAG
CAAAGATCGTCGTCCTCAGCGTCACCGAAGGCGAGGAGAAGCCCCTCAAGTATCCTGGTATCTTCTTCCGCAGCGCGCTG
ATGTTGATGAGTAAGTGCGACTTGCTGCCGTATGTGCCCTTTGACCCGGAACTGGCCGCTCGCAACGCGCGAACCATCCA
TCCCGAAATCGAAGTCGTGCGCCTGTCCGCGTCTAGCGGTGAGGGTTTTGGCGAGTGGATGCAGTGGCTGCACCGCCGGC
TGAGCAAGACTTGCGTAAGCGTGTCCAGCGGCACAGCCAGGCGTTAG

Upstream 100 bases:

>100_bases
CGGTCGCCGAGGGCCTGGTCTTGACGATTGAAACAGGGACCGGAGACCAGTTGGACATCAGTTTCGTAGAGTTGGACGAG
CCGGATTGCGAGGTCAATAA

Downstream 100 bases:

>100_bases
CGCTGCATCGACTCGGAGGCCTGCCTCCGATCTAAACCGAGCTATTGCAATCTGCAATTCACGCAAACACTAAAAATATT
TTCCCCTTCCTTTCAACCGT

Product: hydrogenase accessory protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MRIDIGEKVLQENAKVAAELRAMLTERGIVCVNLIGSPGSGKTAILERTLANLRETPYHVAVLTGDIQTDADAQRLSRYG
FPARQITTGGACHLDARMVLRGMDGWDTDQIDLLLIENVGNLVCPTSYDLGEEAKIVVLSVTEGEEKPLKYPGIFFRSAL
MLMSKCDLLPYVPFDPELAARNARTIHPEIEVVRLSASSGEGFGEWMQWLHRRLSKTCVSVSSGTARR

Sequences:

>Translated_228_residues
MRIDIGEKVLQENAKVAAELRAMLTERGIVCVNLIGSPGSGKTAILERTLANLRETPYHVAVLTGDIQTDADAQRLSRYG
FPARQITTGGACHLDARMVLRGMDGWDTDQIDLLLIENVGNLVCPTSYDLGEEAKIVVLSVTEGEEKPLKYPGIFFRSAL
MLMSKCDLLPYVPFDPELAARNARTIHPEIEVVRLSASSGEGFGEWMQWLHRRLSKTCVSVSSGTARR
>Mature_228_residues
MRIDIGEKVLQENAKVAAELRAMLTERGIVCVNLIGSPGSGKTAILERTLANLRETPYHVAVLTGDIQTDADAQRLSRYG
FPARQITTGGACHLDARMVLRGMDGWDTDQIDLLLIENVGNLVCPTSYDLGEEAKIVVLSVTEGEEKPLKYPGIFFRSAL
MLMSKCDLLPYVPFDPELAARNARTIHPEIEVVRLSASSGEGFGEWMQWLHRRLSKTCVSVSSGTARR

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=202, Percent_Identity=50, Blast_Score=201, Evalue=3e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 25116; Mature: 25116

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIDIGEKVLQENAKVAAELRAMLTERGIVCVNLIGSPGSGKTAILERTLANLRETPYHV
CCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEE
AVLTGDIQTDADAQRLSRYGFPARQITTGGACHLDARMVLRGMDGWDTDQIDLLLIENVG
EEEECCCCCCHHHHHHHHCCCCHHHCCCCCCEEEHHHHHEECCCCCCCCCEEEEEEECCC
NLVCPTSYDLGEEAKIVVLSVTEGEEKPLKYPGIFFRSALMLMSKCDLLPYVPFDPELAA
CEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHH
RNARTIHPEIEVVRLSASSGEGFGEWMQWLHRRLSKTCVSVSSGTARR
CCCEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHEECCCCCCCC
>Mature Secondary Structure
MRIDIGEKVLQENAKVAAELRAMLTERGIVCVNLIGSPGSGKTAILERTLANLRETPYHV
CCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEE
AVLTGDIQTDADAQRLSRYGFPARQITTGGACHLDARMVLRGMDGWDTDQIDLLLIENVG
EEEECCCCCCHHHHHHHHCCCCHHHCCCCCCEEEHHHHHEECCCCCCCCCEEEEEEECCC
NLVCPTSYDLGEEAKIVVLSVTEGEEKPLKYPGIFFRSALMLMSKCDLLPYVPFDPELAA
CEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHH
RNARTIHPEIEVVRLSASSGEGFGEWMQWLHRRLSKTCVSVSSGTARR
CCCEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486288 [H]