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The map label for this gene is yhdN [H]

Identifier: 116625861

GI number: 116625861

Start: 8545918

End: 8546865

Strand: Direct

Name: yhdN [H]

Synonym: Acid_6815

Alternate gene names: 116625861

Gene position: 8545918-8546865 (Clockwise)

Preceding gene: 116625860

Following gene: 116625863

Centisome position: 85.75

GC content: 57.7

Gene sequence:

>948_bases
ATGGTCACCAAATTGTCACGGCGCGATTGGTTGAGCTGGAGTGCCGGCGCGTTAGCGGCACCGCTTTTCGGCAAGTTATT
CGACCACGAAAGAATGCTGACTAAGCCGATTCCGTCGAGCGGCGAGCAACTGCCGGTCATCGGATTAGGCAGCGCGGCTA
CCTTCGCGGTAACCGCGCAATCGGGAGAAATCGCCGATCTCCGCGAAGTGATGATGACGCTGGTGGAACACGGTGGCAAG
ATCTTCGACACTGCTCCGGATTATGGCGCTTCGGAAGCTGTCGCCGGCGAGATCGCGAGTGAAGAGTCGATGGGCAACAA
AATTTTTTGGGCAACCAAAGTAAACGTCGCGCCGGAAAACGGCCGCGCGAACCCGTTCGCCGCCATGTCGCAGATCACTC
GTTCTTTCCGCAGACTCCGGAGGCGCAAGATAGATCTCATCCAGGTCCACAACTTAGGCGATGTGCCGACTCAGTTAGGC
CTTCTGAAGGACCTCAAGGCGCAGGGGCGCGTACGCTACATAGGCGTCACTTCGACTATGTCAAGGCAGTACGACGATTT
GATCAAGATCATGAAATCCGAGCCACTCGATTTCATCGGCGTCAATTATGCAGTGGATGACCGCGCTGTGGAGGATACTA
TCCTGCCGCTAGCACGCGATCGAAAGTTCGCCGTGTTGGCGTATTCGCCGTTCGGGCGGACGCGGTTGTTTCACCGCGTT
GCCGGCCGACCCTTGCCCGATTGGGGGGCTGAGTTCGACGCGAAGACCTGGGCTCAGTTCTTCCTCAAATTCGTCGTGTC
GCATCCTTCGATCCTGGCCGCTACCCCTGCCACCAGCCAGGCAAAGAACATGCTCGATAATATTGGCGGTGGTCTAGGCA
AGATGCCCGATGAGGCAACGCGCAAACGCATGGCCGATTTCGTTGACGCACTTCCGTCGGCGTCCTGA

Upstream 100 bases:

>100_bases
AAGATGGATGGGGCGGGCAGCCCAGTCAGTCGCCAACGACACCTTAGCCCGAAAGGATCTTTCTACGATTGCCGCATCAC
GTTCCGGAAAGGAGAAAGAG

Downstream 100 bases:

>100_bases
ATTACGCAGAAAGAGACATGGCGTTCTCGTCTGATACCACCCGCCCAAGCAATTGATCCCGCTGGCCTATTTTCCAGCCT
CGCCGACTCCAATCTTCATT

Product: aldo/keto reductase

Products: NA

Alternate protein names: GSP69; AKR11B [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MVTKLSRRDWLSWSAGALAAPLFGKLFDHERMLTKPIPSSGEQLPVIGLGSAATFAVTAQSGEIADLREVMMTLVEHGGK
IFDTAPDYGASEAVAGEIASEESMGNKIFWATKVNVAPENGRANPFAAMSQITRSFRRLRRRKIDLIQVHNLGDVPTQLG
LLKDLKAQGRVRYIGVTSTMSRQYDDLIKIMKSEPLDFIGVNYAVDDRAVEDTILPLARDRKFAVLAYSPFGRTRLFHRV
AGRPLPDWGAEFDAKTWAQFFLKFVVSHPSILAATPATSQAKNMLDNIGGGLGKMPDEATRKRMADFVDALPSAS

Sequences:

>Translated_315_residues
MVTKLSRRDWLSWSAGALAAPLFGKLFDHERMLTKPIPSSGEQLPVIGLGSAATFAVTAQSGEIADLREVMMTLVEHGGK
IFDTAPDYGASEAVAGEIASEESMGNKIFWATKVNVAPENGRANPFAAMSQITRSFRRLRRRKIDLIQVHNLGDVPTQLG
LLKDLKAQGRVRYIGVTSTMSRQYDDLIKIMKSEPLDFIGVNYAVDDRAVEDTILPLARDRKFAVLAYSPFGRTRLFHRV
AGRPLPDWGAEFDAKTWAQFFLKFVVSHPSILAATPATSQAKNMLDNIGGGLGKMPDEATRKRMADFVDALPSAS
>Mature_315_residues
MVTKLSRRDWLSWSAGALAAPLFGKLFDHERMLTKPIPSSGEQLPVIGLGSAATFAVTAQSGEIADLREVMMTLVEHGGK
IFDTAPDYGASEAVAGEIASEESMGNKIFWATKVNVAPENGRANPFAAMSQITRSFRRLRRRKIDLIQVHNLGDVPTQLG
LLKDLKAQGRVRYIGVTSTMSRQYDDLIKIMKSEPLDFIGVNYAVDDRAVEDTILPLARDRKFAVLAYSPFGRTRLFHRV
AGRPLPDWGAEFDAKTWAQFFLKFVVSHPSILAATPATSQAKNMLDNIGGGLGKMPDEATRKRMADFVDALPSAS

Specific function: Unknown

COG id: COG0656

COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788070, Length=251, Percent_Identity=26.6932270916335, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1788081, Length=257, Percent_Identity=28.0155642023346, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34583; Mature: 34583

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTKLSRRDWLSWSAGALAAPLFGKLFDHERMLTKPIPSSGEQLPVIGLGSAATFAVTAQ
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEEEEEC
SGEIADLREVMMTLVEHGGKIFDTAPDYGASEAVAGEIASEESMGNKIFWATKVNVAPEN
CCCHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEEECCCC
GRANPFAAMSQITRSFRRLRRRKIDLIQVHNLGDVPTQLGLLKDLKAQGRVRYIGVTSTM
CCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEHHHH
SRQYDDLIKIMKSEPLDFIGVNYAVDDRAVEDTILPLARDRKFAVLAYSPFGRTRLFHRV
HHHHHHHHHHHHHCCCCEEECEEEECCHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHH
AGRPLPDWGAEFDAKTWAQFFLKFVVSHPSILAATPATSQAKNMLDNIGGGLGKMPDEAT
HCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCHHH
RKRMADFVDALPSAS
HHHHHHHHHHCCCCC
>Mature Secondary Structure
MVTKLSRRDWLSWSAGALAAPLFGKLFDHERMLTKPIPSSGEQLPVIGLGSAATFAVTAQ
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEEEEEC
SGEIADLREVMMTLVEHGGKIFDTAPDYGASEAVAGEIASEESMGNKIFWATKVNVAPEN
CCCHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEEECCCC
GRANPFAAMSQITRSFRRLRRRKIDLIQVHNLGDVPTQLGLLKDLKAQGRVRYIGVTSTM
CCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEHHHH
SRQYDDLIKIMKSEPLDFIGVNYAVDDRAVEDTILPLARDRKFAVLAYSPFGRTRLFHRV
HHHHHHHHHHHHHCCCCEEECEEEECCHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHH
AGRPLPDWGAEFDAKTWAQFFLKFVVSHPSILAATPATSQAKNMLDNIGGGLGKMPDEAT
HCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCHHH
RKRMADFVDALPSAS
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 9298659 [H]